Nitrosobenzene (BioDeep_00000006364)

 

Secondary id: BioDeep_00000786551

human metabolite blood metabolite


代谢物信息卡片


Nitrosobenzene, 14C-labeled

化学式: C6H5NO (107.0371)
中文名称: 亚硝基苯
谱图信息: 最多检出来源 Homo sapiens(blood) 32.75%

分子结构信息

SMILES: C1=CC=C(C=C1)N=O
InChI: InChI=1S/C6H5NO/c8-7-6-4-2-1-3-5-6/h1-5H

描述信息

同义名列表

5 个代谢物同义名

Nitrosobenzene, 14C-labeled; NITROSOBENZENE; NOB; Nitrosobenzene; Nitrosobenzene



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 CAT, GAPDH, NAT2, PMP2, XDH
Endoplasmic reticulum membrane 2 CD4, TKT
Nucleus 4 GAPDH, MND1, NAT2, PMP2
cytosol 10 AKR1A1, CAT, GAPDH, GSR, MB, NAT1, NAT2, PMP2, TKT, XDH
nuclear body 1 TKT
nucleoplasm 1 TKT
Cell membrane 6 CD4, CD8A, NAT1, NAT2, SLC38A5, TKT
Multi-pass membrane protein 5 CACNA1F, CACNA1I, NAT1, NAT2, SLC38A5
Synapse 2 AKR1A1, NAT1
cell surface 1 NAT1
neuronal cell body 1 NAT2
presynaptic membrane 1 NAT1
Cytoplasm, cytosol 2 AKR1A1, GAPDH
plasma membrane 8 CACNA1I, CD4, CD8A, GAPDH, NAT1, NAT2, SLC38A5, TKT
synaptic vesicle membrane 1 NAT1
Membrane 7 CACNA1F, CACNA1I, CAT, GAPDH, NAT1, NAT2, SLC38A5
apical plasma membrane 3 AKR1A1, NAT1, TKT
axon 2 NAT1, NAT2
basolateral plasma membrane 2 NAT1, NAT2
extracellular exosome 9 AKR1A1, CAT, GAPDH, GSR, LYZ, MB, NAT2, PMP2, TKT
extracellular space 6 AKR1A1, IL10, IL4, IL5, LYZ, XDH
perinuclear region of cytoplasm 1 GAPDH
mitochondrion 2 CAT, GSR
protein-containing complex 1 CAT
intracellular membrane-bounded organelle 2 CAT, GAPDH
Single-pass type I membrane protein 3 CD4, CD8A, TKT
Secreted 3 IL10, IL4, IL5
extracellular region 6 CAT, CD8A, IL10, IL4, IL5, LYZ
neuronal cell body membrane 1 NAT1
[Isoform 2]: Secreted 1 CD8A
mitochondrial matrix 2 CAT, GSR
transcription regulator complex 1 NAT2
photoreceptor outer segment 1 CACNA1F
nuclear membrane 1 GAPDH
external side of plasma membrane 3 CD4, CD8A, GSR
actin cytoskeleton 1 TKT
perikaryon 1 CACNA1F
microtubule cytoskeleton 1 GAPDH
sarcoplasm 1 MB
Early endosome 1 CD4
vesicle 2 GAPDH, TKT
Apical cell membrane 1 AKR1A1
Cytoplasm, perinuclear region 1 GAPDH
Membrane raft 1 CD4
Cytoplasm, cytoskeleton 1 GAPDH
focal adhesion 2 CAT, TKT
Peroxisome 3 CAT, TKT, XDH
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
receptor complex 2 CD8A, TKT
cytoskeleton 1 GAPDH
Basolateral cell membrane 1 NAT1
Lipid droplet 1 GAPDH
myelin sheath 1 PMP2
plasma membrane raft 1 CD8A
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 1 CD4
voltage-gated calcium channel complex 2 CACNA1F, CACNA1I
specific granule lumen 1 LYZ
tertiary granule lumen 1 LYZ
azurophil granule lumen 1 LYZ
clathrin-coated endocytic vesicle membrane 1 CD4
ribonucleoprotein complex 1 GAPDH
external side of apical plasma membrane 1 NAT2
[Isoform 1]: Cell membrane 1 CD8A
GAIT complex 1 GAPDH
T cell receptor complex 2 CD4, CD8A
Cytoplasm, sarcoplasm 1 MB
catalase complex 1 CAT
NatA complex 1 NAT2


文献列表

  • Subramanian Suganya, Dominic Sophia, Chinthamony Arul Raj, Muthaiyan Ahalliya Rathi, Lakshmanan Thirumoorthi, Periyasamy Meenakshi, Dugganaboyana Guru Kumar, Velliyur Kanniyapan Gopalakrishnan. Amelioration of nitrobenzene-induced nephrotoxicity by the ethanol extract of the herb Euphorbia hirta. Pharmacognosy research. 2011 Jul; 3(3):201-7. doi: 10.4103/0974-8490.85009. [PMID: 22022170]
  • Juan Peng, Jian-Ping Yuan, Chou-Fei Wu, Jiang-Hai Wang. Fucoxanthin, a marine carotenoid present in brown seaweeds and diatoms: metabolism and bioactivities relevant to human health. Marine drugs. 2011; 9(10):1806-1828. doi: 10.3390/md9101806. [PMID: 22072997]
  • Ryosuke Tatsunami, Tadao Yoshioka. Enzymatic and mechanistic studies on the formation of N-phenylglycolohydroxamic acid from nitrosobenzene and pyruvate in spinach leaf homogenate. Journal of agricultural and food chemistry. 2006 Jan; 54(2):590-6. doi: 10.1021/jf051969f. [PMID: 16417326]
  • M Wulferink, J González, C Goebel, E Gleichmann. T cells ignore aniline, a prohapten, but respond to its reactive metabolites generated by phagocytes: possible implications for the pathogenesis of toxic oil syndrome. Chemical research in toxicology. 2001 Apr; 14(4):389-97. doi: 10.1021/tx000214u. [PMID: 11304127]
  • M F Khan, X Wu, G A Ansari. Contribution of nitrosobenzene to splenic toxicity of aniline. Journal of toxicology and environmental health. Part A. 2000 Jun; 60(4):263-73. doi: . [PMID: 10914691]
  • H Iwahashi, C E Parker, R P Mason, K B Tomer. Radical adducts of nitrosobenzene and 2-methyl-2-nitrosopropane with 12,13-epoxylinoleic acid radical, 12,13-epoxylinolenic acid radical and 14,15-epoxyarachidonic acid radical. Identification by h.p.l.c.-e.p.r. and liquid chromatography-thermospray-m.s. The Biochemical journal. 1991 Jun; 276 ( Pt 2)(?):447-53. doi: 10.1042/bj2760447. [PMID: 1646600]