Foscarnet (BioDeep_00000006162)
Secondary id: BioDeep_00001867901
human metabolite blood metabolite Chemicals and Drugs
代谢物信息卡片
Dihydroxyphosphinecarboxylic acid oxide
化学式: CH3O5P (125.97181180000001)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 1.32%
分子结构信息
SMILES: C(=O)(O)P(=O)(O)O
InChI: InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)
描述信息
Foscarnet is only found in individuals that have used or taken this drug. It is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV. [PubChem]Foscarnet exerts its antiviral activity by a selective inhibition at the pyrophosphate binding site on virus-specific DNA polymerases at concentrations that do not affect cellular DNA polymerases.
J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals > J05AD - Phosphonic acid derivatives
C471 - Enzyme Inhibitor > C1589 - Reverse Transcriptase Inhibitor > C97453 - Non-nucleoside Reverse Transcriptase Inhibitor
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D018894 - Reverse Transcriptase Inhibitors
D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors
C254 - Anti-Infective Agent > C281 - Antiviral Agent
同义名列表
31 个代谢物同义名
Dihydroxyphosphinecarboxylic acid oxide; Foscarnet manganese (2+) (2:3) salt; Foscarnet magnesium (2:3) salt; Sodium hexahydrate, foscarnet; Hexahydrate, foscarnet sodium; Tripotassium salt, foscarnet; Foscarnet calcium (2:3) salt; Foscarnet sodium hexahydrate; Foscarnet tripotassium salt; Phosphonoformate, trisodium; Foscarnet barium (2:3) salt; Trisodium phosphonoformate; Trilithium salt, foscarnet; Trisodium salt, foscarnet; Foscarnet trilithium salt; Phgosphonocarboxylic acid; Disodium salt, foscarnet; Foscarnet trisodium salt; Foscarnet disodium salt; Phosphonomethanoic acid; Carboxyphosphonic acid; Phosphonoformic acid; Phosphonomethanoate; Carboxyphosphonate; Sodium, foscarnet; Phosphonoformate; Foscarnet sodium; Foscarmet; foscarnet; Foscavir; PF
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:127780
- KEGG: C06456
- PubChem: 3415
- HMDB: HMDB0014670
- Metlin: METLIN2957
- DrugBank: DB00529
- ChEMBL: CHEMBL666
- Wikipedia: Foscarnet
- MeSH: Foscarnet
- KNApSAcK: C00000800
- chemspider: 3297
- CAS: 4428-95-9
- PMhub: MS000019155
- PubChem: 8689
- PDB-CCD: PPF
- 3DMET: B02031
- NIKKAJI: J11.016G
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yi Zhang, Lei Fang, Yi Zhou, Yongqing Zhang, Bing Liang, Chuanzhu Yan, Ling Li. A case report of long-delayed diagnosis of pseudorabies virus encephalitis with endophthalmitis: lessons from metagenomic next generation sequencing.
BMC neurology.
2023 May; 23(1):192. doi:
10.1186/s12883-023-03227-1. [PMID: 37194001] - Kei Irie, Nobuhiro Hiramoto, Takayuki Ishikawa, Shoji Fukushima. Use of liquid chromatography-tandem mass spectrometry for foscarnet quantification in human serum and cerebrospinal fluid.
Rapid communications in mass spectrometry : RCM.
2022 Apr; 36(7):e9255. doi:
10.1002/rcm.9255. [PMID: 35001441] - Ryo Inose, Katsuyuki Takahashi, Masaya Takahashi, Takashi Sugimoto, Satoru Nanno, Masayuki Hino, Katsuya Nagayama. Long-term use of foscarnet is associated with an increased incidence of acute kidney injury in hematopoietic stem cell transplant patients: A retrospective observational study.
Transplant infectious disease : an official journal of the Transplantation Society.
2022 Apr; 24(2):e13804. doi:
10.1111/tid.13804. [PMID: 35114030] - Minwen Ding, Qian Zhang, Minmin Zhang, Xinxin Jiang, Mengjing Wang, Li Ni, Wen Gong, Bihong Huang, Jing Chen. Phosphate Overload Stimulates Inflammatory Reaction via PiT-1 and Induces Vascular Calcification in Uremia.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation.
2022 03; 32(2):178-188. doi:
10.1053/j.jrn.2021.03.008. [PMID: 34688540] - Elena Rho, Bettina Näf, Thomas F Müller, Rudolf P Wüthrich, Thomas Schachter, Seraina von Moos. Use of letermovir-valganciclovir combination as a step-down treatment after foscarnet for ganciclovir-resistant CMV infection in kidney transplant recipients.
Clinical transplantation.
2021 11; 35(11):e14401. doi:
10.1111/ctr.14401. [PMID: 34181768] - Paul E Rosenstiel, Glen S Markowitz, Brigani Amante. An Unusual Cause of Kidney Allograft Dysfunction.
Kidney360.
2021 07; 2(7):1207-1208. doi:
10.34067/kid.0001062021. [PMID: 35368358] - Walter Domingo, Isabelle T Nguyen, Joyce J Johnsrud, Janice Wes Brown. Continuous-Infusion Foscarnet Facilitates Administration in Hematopoietic Stem Cell Transplantation Patients.
Transplantation and cellular therapy.
2021 07; 27(7):622.e1-622.e5. doi:
10.1016/j.jtct.2021.03.018. [PMID: 33891883] - Francesco Baldo, Nicolás M Suárez, Andrew J Davison, Davide Zanon, Egidio Barbi, Natalia Maximova. Post-HSCT graft failure due to refractory human cytomegalovirus successfully treated with haploidentical donor-derived immunoglobulins and stem cell graft infusion: A case report.
Antiviral research.
2021 04; 188(?):105024. doi:
10.1016/j.antiviral.2021.105024. [PMID: 33577809] - Jerica Pleško, Damjan Kovač, Zoran Arsov, Jelka Lindič, Andrej Škoberne, Dušan Ferluga, Nika Kojc. Glomerular and tubulointerstitial foscarnet nephropathy of kidney allograft with emphasis on ultrastructural findings: A case report.
Clinical nephrology.
2021 Sup; 96(1):127-132. doi:
10.5414/cnp96s23. [PMID: 34643504] - Gena G Foster, Michael J Grant, Samantha M Thomas, Blake Cameron, Doug Raiff, Kelly Corbet, Gavin Loitsch, Christopher Ferreri, Mitchell Horwitz. Treatment with Foscarnet after Allogeneic Hematopoietic Cell Transplant (Allo-HCT) Is Associated with Long-Term Loss of Renal Function.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2020 09; 26(9):1597-1606. doi:
10.1016/j.bbmt.2020.05.007. [PMID: 32450288] - Y Uwai, R Kondo, T Suzuki, T Kawasaki, T Nabekura. Potent Inhibition of Biphasic Tubular Reabsorption of Lithium by Acetazolamide and Foscarnet in Rats.
Physiological research.
2020 08; 69(4):645-651. doi:
10.33549/physiolres.934285. [PMID: 32584131] - Ryosuke Ota, Atsushi Hirata, Keisuke Noto, Satoshi Yokoyama, Kouichi Hosomi, Mitsutaka Takada, Hiroshi Matsuoka. Relationship between serum calcium and creatinine in hematopoietic stem cell transplantation patients treated with foscarnet
.
International journal of clinical pharmacology and therapeutics.
2020 May; 58(5):274-281. doi:
10.5414/cp203650. [PMID: 32101522] - Masaya Takahashi, Katsuyuki Takahashi, Ryo Inose, Takashi Sugimoto, Hideo Koh, Masayuki Hino, Katsuya Nagayama. Safety profile of the concomitant use of foscarnet and aerosolized pentamidine in allogeneic hematopoietic stem cell transplantation recipients.
Transplant infectious disease : an official journal of the Transplantation Society.
2020 Feb; 22(1):e13239. doi:
10.1111/tid.13239. [PMID: 31883423] - Po Yee Mia Leung, Thomas Tran, Adam Testro, Kathy Paizis, Jason Kwong, John B Whitlam. Ganciclovir-resistant post-transplant cytomegalovirus infection due to combined deletion mutation at codons 595-596 of the UL97 gene.
Transplant infectious disease : an official journal of the Transplantation Society.
2019 Dec; 21(6):e13168. doi:
10.1111/tid.13168. [PMID: 31498954] - Michael L Spinner, Simon W Lam, Christine E Koval, Vasilios Athans. Recommended foscarnet dose is not associated with improved outcomes in cytomegalovirus salvage therapy.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.
2019 11; 120(?):12-16. doi:
10.1016/j.jcv.2019.09.001. [PMID: 31514101] - Y Nawashiro, K Shiraki, S Yamamoto, K Takizawa, Y Sasada, M Suehiro, K Miura, M Hattori, T Daikoku, M Hisano. Persistent Primary Cytomegalovirus Infection After Deceased Donor Kidney Transplant: Ganciclovir Susceptibility of Human Cytomegalovirus With UL97 D605E Mutation: A Case Report.
Transplantation proceedings.
2018 Dec; 50(10):3932-3936. doi:
10.1016/j.transproceed.2018.09.010. [PMID: 30577289] - Masao Ogata, Kuniko Takano, Yukiyoshi Moriuchi, Tadakazu Kondo, Toshimitsu Ueki, Nobuaki Nakano, Takehiko Mori, Nobuhiko Uoshima, Koji Nagafuji, Satoshi Yamasaki, Yasuhiko Shibasaki, Rika Sakai, Koji Kato, Ilseung Choi, Yumi Jo, Tetsuya Eto, Shinichi Kako, Kumi Oshima, Takahiro Fukuda. Effects of Prophylactic Foscarnet on Human Herpesvirus-6 Reactivation and Encephalitis in Cord Blood Transplant Recipients: A Prospective Multicenter Trial with an Historical Control Group.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2018 06; 24(6):1264-1273. doi:
10.1016/j.bbmt.2018.02.008. [PMID: 29454651] - Kevin J Filipski, Matthew F Sammons, Samit K Bhattacharya, Jane Panteleev, Janice A Brown, Paula M Loria, Markus Boehm, Aaron C Smith, Andre Shavnya, Edward L Conn, Kun Song, Yan Weng, Carie Facemire, Harald Jüppner, Valerie Clerin. Discovery of Orally Bioavailable Selective Inhibitors of the Sodium-Phosphate Cotransporter NaPi2a (SLC34A1).
ACS medicinal chemistry letters.
2018 May; 9(5):440-445. doi:
10.1021/acsmedchemlett.8b00013. [PMID: 29795756] - M Cintra-Cabrera, A Suárez-Benjumea, G Bernal-Blanco, F M González-Roncero, N G Toapanta-Gaibor, M Súñer-Poblet, M Á Pérez-Valdivia, F Fernández-Cuenca, M Á Gentil-Govantes, J L Rocha-Castilla. Resistant Cytomegalovirus Infection After Renal Transplantation: Literature Review.
Transplantation proceedings.
2018 Mar; 50(2):575-577. doi:
10.1016/j.transproceed.2017.09.058. [PMID: 29579856] - Toshimitsu Ueki, Kenichi Hoshi, Yuki Hiroshima, Masahiko Sumi, Naoaki Ichikawa, Masao Ogata, Takako Satou, Takahiro Fukuda, Hikaru Kobayashi. Analysis of five cases of human herpesvirus-6 myelitis among 121 cord blood transplantations.
International journal of hematology.
2018 Mar; 107(3):363-372. doi:
10.1007/s12185-017-2347-5. [PMID: 29022282] - Yuichi Uwai, Tatsuya Kawasaki, Tomohiro Nabekura. Nonlinear disposition of lithium in rats and saturation of its tubular reabsorption by the sodium-phosphate cotransporter as a cause.
Biopharmaceutics & drug disposition.
2018 Feb; 39(2):83-87. doi:
10.1002/bdd.2116. [PMID: 29214648] - K M Baradhi, R L Aure, J-M El-Amm. High-dose Valganciclovir Treatment for Resistant Cytomegalovirus Colitis due to UL97 and UL54 Mutations.
Transplantation proceedings.
2018 Jan; 50(1):142-144. doi:
10.1016/j.transproceed.2017.11.013. [PMID: 29407298] - Lorraine Py Kwan, Maggie My Mok, Bo Ying Choy, Tak Mao Chan. Acute kidney injury in a renal transplant recipient due to concomitant use of vancomycin and foscarnet.
Nephrology (Carlton, Vic.).
2017 10; 22(10):821-822. doi:
10.1111/nep.12947. [PMID: 28921753] - I A Echenique, D Beltran, L Ramirez-Ruiz, N Najafian, N Agrawal. Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report.
Transplantation proceedings.
2017 Sep; 49(7):1560-1564. doi:
10.1016/j.transproceed.2017.02.046. [PMID: 28838440] - J Bruminhent, P Rotjanapan, S P Watcharananan. Epidemiology and Outcome of Ganciclovir-Resistant Cytomegalovirus Infection After Solid Organ Transplantation: A Single Transplant Center Experience in Thailand.
Transplantation proceedings.
2017 06; 49(5):1048-1052. doi:
10.1016/j.transproceed.2017.03.053. [PMID: 28583524] - Scott D Schoenberger, Stephen J Kim, Jennifer E Thorne, Prithvi Mruthyunjaya, Steven Yeh, Sophie J Bakri, Justis P Ehlers. Diagnosis and Treatment of Acute Retinal Necrosis: A Report by the American Academy of Ophthalmology.
Ophthalmology.
2017 03; 124(3):382-392. doi:
10.1016/j.ophtha.2016.11.007. [PMID: 28094044] - Janine Mihm, Sarah Leyking, Jan Dirks, Sigrun Smola, Danilo Fliser, Urban Sester, Martina Sester, Heinrike Wilkens, Jürgen Rissland. Immune-based guidance of foscarnet treatment duration in a transplant recipient with ganciclovir-resistant cytomegalovirus infection.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.
2016 09; 82(?):5-8. doi:
10.1016/j.jcv.2016.06.013. [PMID: 27389910] - Qinglan Guo, Adam D Tomich, Christi L McElheny, Vaughn S Cooper, Nicole Stoesser, Minggui Wang, Nicolas Sluis-Cremer, Yohei Doi. Glutathione-S-transferase FosA6 of Klebsiella pneumoniae origin conferring fosfomycin resistance in ESBL-producing Escherichia coli.
The Journal of antimicrobial chemotherapy.
2016 09; 71(9):2460-5. doi:
10.1093/jac/dkw177. [PMID: 27261267] - Tristan Delory, Emmanuelle Papot, Christophe Rioux, Charlotte Charpentier, Claire Auge-Courtoi, Florence Michard, Gilles Peytavin, Diane Descamps, Sophie Matheron, Yazdan Yazdanpanah. Foscarnet, zidovudine and dolutegravir combination efficacy and tolerability for late stage HIV salvage therapy: A case-series experience.
Journal of medical virology.
2016 Jul; 88(7):1204-10. doi:
10.1002/jmv.24442. [PMID: 26636432] - Daiki Iwami, Yayoi Ogawa, Hiromi Fujita, Ken Morita, Hajime Sasaki, Yuichiro Oishi, Haruka Higuchi, Kanako Hatanaka, Nobuo Shinohara. Successful treatment with foscarnet for ganciclovir-resistant cytomegalovirus infection in a kidney transplant recipient: A case report.
Nephrology (Carlton, Vic.).
2016 Jul; 21 Suppl 1(?):63-6. doi:
10.1111/nep.12767. [PMID: 26970406] - Isabelle Garrigue, Rémi Moulinas, Patricia Recordon-Pinson, Marie-Laure Delacour, Marie Essig, Hannah Kaminski, Jean-Philippe Rerolle, Pierre Merville, Hervé Fleury, Sophie Alain. Contribution of next generation sequencing to early detection of cytomegalovirus UL97 emerging mutants and viral subpopulations analysis in kidney transplant recipients.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.
2016 07; 80(?):74-81. doi:
10.1016/j.jcv.2016.04.017. [PMID: 27214758] - Yuichi Uwai, Tatsuya Kawasaki, Tomohiro Nabekura. Foscarnet, an inhibitor of the sodium-phosphate cotransporter NaPi-IIa, inhibits phosphorylation of glycogen synthase kinase-3β by lithium in the rat kidney cortex.
Drug metabolism and pharmacokinetics.
2016 Jun; 31(3):256-9. doi:
10.1016/j.dmpk.2016.02.003. [PMID: 27238574] - G W Kang, H L Hong, I H Lee, K S Ahn, J D Kim, D L Choi. Ganciclovir and Foscarnet Therapy of Cytomegalovirus-Associated Meningoencephalitis in a Hemodialysis Patient With Liver Transplantation: Case Report.
Transplantation proceedings.
2016 May; 48(4):1208-11. doi:
10.1016/j.transproceed.2016.01.021. [PMID: 27320588] - Rong Zhou, Xin Kang, Bo Tang, Chandra Mohan, Tianfu Wu, Ai Peng, Jun-Yan Liu. Ornithine is a key mediator in hyperphosphatemia-mediated human umbilical vein endothelial cell apoptosis: Insights gained from metabolomics.
Life sciences.
2016 Feb; 146(?):73-80. doi:
10.1016/j.lfs.2016.01.003. [PMID: 26773858] - Linto Thomas, Carsten A Wagner, Jürg Biber, Nati Hernando. Adaptation of Opossum Kidney Cells to Luminal Phosphate: Effects of Phosphonoformic Acid and Kinase Inhibitors.
Kidney & blood pressure research.
2016; 41(3):298-310. doi:
10.1159/000443432. [PMID: 27165344] - Madeleine S Didsbury, Fiona E Mackie, Sean E Kennedy. A systematic review of acute kidney injury in pediatric allogeneic hematopoietic stem cell recipients.
Pediatric transplantation.
2015 Aug; 19(5):460-70. doi:
10.1111/petr.12483. [PMID: 25963934] - Yu-Juei Hsu, Shih-Che Hsu, Shih-Ming Huang, Herng-Sheng Lee, Shih-Hua Lin, Chien-Sung Tsai, Chun-Che Shih, Chih-Yuan Lin. Hyperphosphatemia induces protective autophagy in endothelial cells through the inhibition of Akt/mTOR signaling.
Journal of vascular surgery.
2015 Jul; 62(1):210-221.e2. doi:
10.1016/j.jvs.2014.02.040. [PMID: 24797554] - M B Marzal-Alfaro, S Manrique-Rodríguez, A Alcaraz Romero, M García San Prudencio, C M Fernández-Llamazares. [Systemic cytomegalovirus infection: changes in serum calcium and magnesium levels with foscarnet treatment].
Anales de pediatria (Barcelona, Spain : 2003).
2015 Jan; 82(1):e170-4. doi:
10.1016/j.anpedi.2014.03.021. [PMID: 24785445] - Carole Philipponnet, Pierre-Antoine Michel, Michel Daudon, Isabelle Brocheriou, Jean-Jacques Boffa. Intravascular foscarnet crystal precipitation causing multiorgan failure.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2015 Jan; 65(1):152-5. doi:
10.1053/j.ajkd.2014.07.024. [PMID: 25301103] - Chandrav De, Dongmei Liu, Bo Zheng, Uma S Singh, Satish Chavre, Catherine White, Robert D Arnold, Fred K Hagen, Chung K Chu, Jennifer F Moffat. β-l-1-[5-(E-2-bromovinyl)-2-(hydroxymethyl)-1,3-(dioxolan-4-yl)] uracil (l-BHDU) prevents varicella-zoster virus replication in a SCID-Hu mouse model and does not interfere with 5-fluorouracil catabolism.
Antiviral research.
2014 Oct; 110(?):10-9. doi:
10.1016/j.antiviral.2014.07.007. [PMID: 25051026] - Yuichi Uwai, Ryosuke Arima, Chihiro Takatsu, Ryo Furuta, Tatsuya Kawasaki, Tomohiro Nabekura. Sodium-phosphate cotransporter mediates reabsorption of lithium in rat kidney.
Pharmacological research.
2014 Sep; 87(?):94-8. doi:
10.1016/j.phrs.2014.06.012. [PMID: 24997387] - Sunwen Chou, Ronald J Ercolani, Malaya K Sahoo, Martina I Lefterova, Lynne M Strasfeld, Benjamin A Pinsky. Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing.
Antimicrobial agents and chemotherapy.
2014 Aug; 58(8):4697-702. doi:
10.1128/aac.03214-14. [PMID: 24890586] - Ana Martín-Pardillos, Cecilia Sosa, Ángel Millán, Víctor Sorribas. Effect of water fluoridation on the development of medial vascular calcification in uremic rats.
Toxicology.
2014 Apr; 318(?):40-50. doi:
10.1016/j.tox.2014.01.012. [PMID: 24561004] - Lucio R Minces, M Hong Nguyen, Dimitra Mitsani, Ryan K Shields, Eun J Kwak, Fernanda P Silveira, Rima Abdel-Massih, Joseph M Pilewski, Maria M Crespo, Christian Bermudez, Jay K Bhama, Yoshiya Toyoda, Cornelius J Clancy. Ganciclovir-resistant cytomegalovirus infections among lung transplant recipients are associated with poor outcomes despite treatment with foscarnet-containing regimens.
Antimicrobial agents and chemotherapy.
2014; 58(1):128-35. doi:
10.1128/aac.00561-13. [PMID: 24145525] - Nicole A Nadlonek, Joon H Lee, Michael J Weyant, Xianzhong Meng, David A Fullerton. ox-LDL induces PiT-1 expression in human aortic valve interstitial cells.
The Journal of surgical research.
2013 Sep; 184(1):6-9. doi:
10.1016/j.jss.2013.05.001. [PMID: 23849774] - Scott H James, Nathan B Price, Caroll B Hartline, E Randall Lanier, Mark N Prichard. Selection and recombinant phenotyping of a novel CMX001 and cidofovir resistance mutation in human cytomegalovirus.
Antimicrobial agents and chemotherapy.
2013 Jul; 57(7):3321-5. doi:
10.1128/aac.00062-13. [PMID: 23650158] - Marios Papasotiriou, Evangelos Papachristou, Markos Marangos, Maria Koukoulaki, Eirini Savvidaki, Pantelitsa Kalliakmani, Dimitrios S Goumenos. Cytomegalovirus polyradiculopathy of late onset in a young renal transplant recipient.
Clinical nephrology.
2013 Jul; 80(1):75-8. doi:
10.5414/cn107479. [PMID: 23803598] - T Kawaguchi, M Takeuchi, C Kawajiri, D Abe, Y Nagao, A Yamazaki, Y Sugita, S Tsukamoto, S Sakai, Y Takeda, C Ohwada, E Sakaida, N Shimizu, K Yokote, T Iseki, C Nakaseko. Severe hyponatremia caused by syndrome of inappropriate secretion of antidiuretic hormone developed as initial manifestation of human herpesvirus-6-associated acute limbic encephalitis after unrelated bone marrow transplantation.
Transplant infectious disease : an official journal of the Transplantation Society.
2013 Apr; 15(2):E54-7. doi:
10.1111/tid.12029. [PMID: 23173742] - Ian C Forster, Nati Hernando, Jürg Biber, Heini Murer. Phosphate transporters of the SLC20 and SLC34 families.
Molecular aspects of medicine.
2013 Apr; 34(2-3):386-95. doi:
10.1016/j.mam.2012.07.007. [PMID: 23506879] - M Ogata, T Satou, Y Inoue, K Takano, T Ikebe, T Ando, J Ikewaki, K Kohno, A Nishida, M Saburi, Y Miyazaki, E Ohtsuka, Y Saburi, T Fukuda, J Kadota. Foscarnet against human herpesvirus (HHV)-6 reactivation after allo-SCT: breakthrough HHV-6 encephalitis following antiviral prophylaxis.
Bone marrow transplantation.
2013 Feb; 48(2):257-64. doi:
10.1038/bmt.2012.121. [PMID: 22750998] - Verena Tischler, Macé M Schuurmans, Annette Boehler, Ariana Gaspert. Crystal precipitation and granulomatous inflammation in multiple organs after foscarnet therapy in a lung transplant recipient.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
2012 Sep; 31(9):1037-40. doi:
10.1016/j.healun.2012.05.008. [PMID: 22766024] - Tomasz Tomasik, Barbara Zawilińska, Dorota Pawlik, Justyna Ferek, Justyna Ferek, Anna Wójtowicz, Magda Rybak-Krzyszkowska, Ryszard Lauterbach, Jacek J Pietrzyk. [Congenital cytomegaly in one twin - a case report].
Medycyna wieku rozwojowego.
2012 Jul; 16(3):252-60. doi:
NULL. [PMID: 23378403] - Irmeli Lautenschlager, Raymund R Razonable. Human herpesvirus-6 infections in kidney, liver, lung, and heart transplantation: review.
Transplant international : official journal of the European Society for Organ Transplantation.
2012 May; 25(5):493-502. doi:
10.1111/j.1432-2277.2012.01443.x. [PMID: 22356254] - Hart B Moss, Sai Chavala, Emil Say, Melissa B Miller. Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma.
Journal of clinical microbiology.
2012 May; 50(5):1796-9. doi:
10.1128/jcm.00029-12. [PMID: 22337988] - Petra M Goldsmith, Mir Mubariz Husain, Andrew Carmichael, Hongyi Zhang, Stephen J Middleton. Case report: Multidrug-resistant cytomegalovirus in a modified multivisceral transplant recipient.
Transplantation.
2012 Apr; 93(7):e30-2. doi:
10.1097/tp.0b013e318249b163. [PMID: 22450598] - Erin J Plosa, Jennifer C Esbenshade, M Paige Fuller, Jörn-Hendrik Weitkamp. Cytomegalovirus infection.
Pediatrics in review.
2012 Apr; 33(4):156-63; quiz 163. doi:
10.1542/pir.33-4-156. [PMID: 22474112] - K Ishiyama, T Katagiri, K Ohata, K Hosokawa, Y Kondo, H Yamazaki, A Takami, S Nakao. Safety of pre-engraftment prophylactic foscarnet administration after allogeneic stem cell transplantation.
Transplant infectious disease : an official journal of the Transplantation Society.
2012 Feb; 14(1):33-9. doi:
10.1111/j.1399-3062.2011.00662.x. [PMID: 21794043] - Ming Zeng, Xiaoyun Wang, Xiaobing Wang, Xiufen Zhao. Effects of phosphonoformic acid and renagel on renal type IIa sodium-dependent phosphate cotransporter mRNA expression in hyperphosphatemia rats.
Renal failure.
2012; 34(3):358-63. doi:
10.3109/0886022x.2011.647341. [PMID: 22260362] - Mitsutaka Nishimoto, Hirohisa Nakamae, Yoshiki Hayashi, Hideo Koh, Takahiko Nakane, Masahiro Yoshida, Masato Bingo, Hiroshi Okamura, Mizuki Aimoto, Satoru Nanno, Takuro Yoshimura, Akiko Inaba, Kiyoyuki Hagihara, Mika Nakamae, Asao Hirose, Yoshitaka Nakao, Yoshiki Terada, Masayuki Hino. Prolonged sinus tachycardia caused by human herpesvirus 6 (HHV6) encephalomyelitis after allogeneic bone marrow transplantation.
Internal medicine (Tokyo, Japan).
2012; 51(10):1265-7. doi:
10.2169/internalmedicine.51.6640. [PMID: 22687802] - Paula Faral-Tello, Santiago Mirazo, Carmelo Dutra, Andrés Pérez, Lucía Geis-Asteggiante, Sandra Frabasile, Elina Koncke, Danilo Davyt, Lucía Cavallaro, Horacio Heinzen, Juan Arbiza. Cytotoxic, virucidal, and antiviral activity of South American plant and algae extracts.
TheScientificWorldJournal.
2012; 2012(?):174837. doi:
10.1100/2012/174837. [PMID: 22619617] - Jovana Cukuranovic, Sladjana Ugrenovic, Ivan Jovanovic, Milan Visnjic, Vladisav Stefanovic. Viral infection in renal transplant recipients.
TheScientificWorldJournal.
2012; 2012(?):820621. doi:
10.1100/2012/820621. [PMID: 22654630] - Iti Som, Kashish Bhatia, Mohd Yasir. Status of surfactants as penetration enhancers in transdermal drug delivery.
Journal of pharmacy & bioallied sciences.
2012 Jan; 4(1):2-9. doi:
10.4103/0975-7406.92724. [PMID: 22368393] - Shin-Pung P Jen, Roopali Sharma, Sandeep Kochar. Probable acyclovir-induced angioedema in a patient with HIV infection and suspected varicella-zoster virus encephalitis.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
2011 Dec; 68(23):2257-60. doi:
10.2146/ajhp100639. [PMID: 22095814] - M Angeles Marcos. [Resistance studies: when are they indicated?].
Enfermedades infecciosas y microbiologia clinica.
2011 Dec; 29 Suppl 6(?):24-7. doi:
10.1016/s0213-005x(11)70053-2. [PMID: 22541918] - Angela Capobianchi, Anna Paola Iori, Francesca Romana Mauro, Giovanni Fernando Torelli, Alessandra Micozzi, Corrado Girmenia, Robin Foà, Giuseppe Gentile. Longitudinal analysis of human herpesvirus-8 DNA and antibodies in an Italian allogeneic stem cell transplant recipient.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.
2011 Nov; 52(3):247-50. doi:
10.1016/j.jcv.2011.07.003. [PMID: 21839673] - Garima Mishra, Sudha Rao Chandrashekhar. Management of diabetes insipidus in children.
Indian journal of endocrinology and metabolism.
2011 Sep; 15 Suppl 3(?):S180-7. doi:
10.4103/2230-8210.84858. [PMID: 22029022] - Hans-Arne Myhre, Dagny Haug Dorenberg, Knut Ivan Kristiansen, Halvor Rollag, Torbjørn Leivestad, Anders Asberg, Anders Hartmann. Incidence and outcomes of ganciclovir-resistant cytomegalovirus infections in 1244 kidney transplant recipients.
Transplantation.
2011 Jul; 92(2):217-23. doi:
10.1097/tp.0b013e31821fad25. [PMID: 21685829] - K Ishiyama, T Katagiri, T Hoshino, T Yoshida, M Yamaguchi, S Nakao. Preemptive therapy of human herpesvirus-6 encephalitis with foscarnet sodium for high-risk patients after hematopoietic SCT.
Bone marrow transplantation.
2011 Jun; 46(6):863-9. doi:
10.1038/bmt.2010.201. [PMID: 20838386] - Khalid A Enan, Hanna Rennert, Ali M El-Eragi, Abdel Rahim M El Hussein, Isam M Elkhidir. Comparison of Real-time PCR to ELISA for the detection of human cytomegalovirus infection in renal transplant patients in the Sudan.
Virology journal.
2011 May; 8(?):222. doi:
10.1186/1743-422x-8-222. [PMID: 21569506] - Antoinette A T P Brink, Michel van Gelder, Petra F Wolffs, Cathrien A Bruggeman, Inge H M van Loo. Compartmentalization of acyclovir-resistant varicella zoster virus: implications for sampling in molecular diagnostics.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2011 Apr; 52(8):982-7. doi:
10.1093/cid/cir079. [PMID: 21460310] - Eric J Tsang, Christopher K Arakawa, Patricia A Zuk, Benjamin M Wu. Osteoblast interactions within a biomimetic apatite microenvironment.
Annals of biomedical engineering.
2011 Apr; 39(4):1186-200. doi:
10.1007/s10439-010-0245-6. [PMID: 21234689] - Lilia I Melnik, Robert F Garry, Cindy A Morris. Peptide inhibition of human cytomegalovirus infection.
Virology journal.
2011 Feb; 8(?):76. doi:
10.1186/1743-422x-8-76. [PMID: 21342525] - Alexandra Heininger, Helene Haeberle, Imma Fischer, Robert Beck, Reimer Riessen, Frank Rohde, Christoph Meisner, Gerhard Jahn, Alfred Koenigsrainer, Klaus Unertl, Klaus Hamprecht. Cytomegalovirus reactivation and associated outcome of critically ill patients with severe sepsis.
Critical care (London, England).
2011; 15(2):R77. doi:
10.1186/cc10069. [PMID: 21362193] - Jason W Ashley, Zhenqi Shi, Haibo Zhao, Xingsheng Li, Robert A Kesterson, Xu Feng. Genetic ablation of CD68 results in mice with increased bone and dysfunctional osteoclasts.
PloS one.
2011; 6(10):e25838. doi:
10.1371/journal.pone.0025838. [PMID: 21991369] - Ai Peng, Tianfu Wu, Caihong Zeng, Dinesh Rakheja, Jiankun Zhu, Ting Ye, Jack Hutcheson, Nosratola D Vaziri, Zhihong Liu, Chandra Mohan, Xin J Zhou. Adverse effects of simulated hyper- and hypo-phosphatemia on endothelial cell function and viability.
PloS one.
2011; 6(8):e23268. doi:
10.1371/journal.pone.0023268. [PMID: 21858050] - Arnaud Dessombz, Dominique Bazin, Paul Dumas, Christophe Sandt, Josep Sule-Suso, Michel Daudon. Shedding light on the chemical diversity of ectopic calcifications in kidney tissues: diagnostic and research aspects.
PloS one.
2011; 6(11):e28007. doi:
10.1371/journal.pone.0028007. [PMID: 22125652] - Robert Kalyesubula, Mark A Perazella. Nephrotoxicity of HAART.
AIDS research and treatment.
2011; 2011(?):562790. doi:
10.1155/2011/562790. [PMID: 21860787] - Nada Madi, Widad Al-Nakib, Alexander Pacsa. Does Cytomegalovirus Develop Resistance following Antiviral Prophylaxis and Treatment in Renal Transplant Patients in Kuwait?.
Advances in virology.
2011; 2011(?):260561. doi:
10.1155/2011/260561. [PMID: 22312337] - Masako Shimamura, Joanne E Murphy-Ullrich, William J Britt. Human cytomegalovirus induces TGF-β1 activation in renal tubular epithelial cells after epithelial-to-mesenchymal transition.
PLoS pathogens.
2010 Nov; 6(11):e1001170. doi:
10.1371/journal.ppat.1001170. [PMID: 21079788] - Meav-Lang J Lay, Robyn M Lucas, Mala Ratnamohan, Janette Taylor, Anne-Louise Ponsonby, Dominic E Dwyer. Measurement of Epstein-Barr virus DNA load using a novel quantification standard containing two EBV DNA targets and SYBR Green I dye.
Virology journal.
2010 Sep; 7(?):252. doi:
10.1186/1743-422x-7-252. [PMID: 20860842] - Nicolas Picard, Paola Capuano, Gerti Stange, Marija Mihailova, Brigitte Kaissling, Heini Murer, Jürg Biber, Carsten A Wagner. Acute parathyroid hormone differentially regulates renal brush border membrane phosphate cotransporters.
Pflugers Archiv : European journal of physiology.
2010 Aug; 460(3):677-87. doi:
10.1007/s00424-010-0841-1. [PMID: 20526720] - Y Kanda, T Yamashita, T Mori, T Ito, K Tajika, S Mori, T Sakura, M Hara, K Mitani, M Kurokawa, K Akashi, M Harada. A randomized controlled trial of plasma real-time PCR and antigenemia assay for monitoring CMV infection after unrelated BMT.
Bone marrow transplantation.
2010 Aug; 45(8):1325-32. doi:
10.1038/bmt.2009.337. [PMID: 19966850] - Ying Jiang, Mei Wang. Overexpression of parathyroid pituitary-specific transcription factor (Pit)-1 in hyperphosphatemia-induced hyperparathyroidism of chronic renal failure rats.
Chinese medical journal.
2010 Jun; 123(12):1566-70. doi:
. [PMID: 20819513] - Shih-Hua Lin, Sung-Sen Yang, Tom Chau. A practical approach to genetic hypokalemia.
Electrolyte & blood pressure : E & BP.
2010 Jun; 8(1):38-50. doi:
10.5049/ebp.2010.8.1.38. [PMID: 21468196] - Albert J Eid, Raymund R Razonable. New developments in the management of cytomegalovirus infection after solid organ transplantation.
Drugs.
2010 May; 70(8):965-81. doi:
10.2165/10898540-000000000-00000. [PMID: 20481654] - Sophie Stegmann, Maria Elena Manea, Charlotte Charpentier, Florence Damond, Marina Karmochkine, Didier Laureillard, Ali Si-Mohamed, Laurence Weiss, Christophe Piketty. Foscarnet as salvage therapy in HIV-2-infected patient with antiretroviral treatment failure.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.
2010 Jan; 47(1):79-81. doi:
10.1016/j.jcv.2009.11.008. [PMID: 19962343] - Ali Akcay, Kultigin Turkmen, DongWon Lee, Charles L Edelstein. Update on the diagnosis and management of acute kidney injury.
International journal of nephrology and renovascular disease.
2010; 3(?):129-40. doi:
10.2147/ijnrd.s8641. [PMID: 21694939] - Kristel De Keyzer, Steven Van Laecke, Patrick Peeters, Raymond Vanholder. De novo thrombotic microangiopathy induced by cytomegalovirus infection leading to renal allograft loss.
American journal of nephrology.
2010; 32(5):491-6. doi:
10.1159/000321328. [PMID: 20975262] - Douglas A Jabs, Barbara K Martin, Michael S Forman. Mortality associated with resistant cytomegalovirus among patients with cytomegalovirus retinitis and AIDS.
Ophthalmology.
2010 Jan; 117(1):128-132.e2. doi:
10.1016/j.ophtha.2009.06.016. [PMID: 19818505] - Tomasz Tomasik, Agnieszka Opozda, Jacek Józef Pietrzyk. [Cytomegalovirus infection--diagnostic and therapeutic difficulties in neonatal intensive care unit].
Przeglad lekarski.
2010; 67(1):18-24. doi:
NULL. [PMID: 20509566] - T Mori, K Tanaka-Taya, H Satoh, Y Aisa, R Yamazaki, J Kato, Y Ikeda, S Okamoto. Transmission of chromosomally integrated human herpesvirsus 6 (HHV-6) variant A from a parent to children leading to misdiagnosis of active HHV-6 infection.
Transplant infectious disease : an official journal of the Transplantation Society.
2009 Dec; 11(6):503-6. doi:
10.1111/j.1399-3062.2009.00430.x. [PMID: 19656346] - P Rautenberg, L Grancicova, J Hillenkamp, B Nölle, J B Roider, H Fickenscher. [Acute retinal necrosis from the virologist's perspective].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft.
2009 Dec; 106(12):1065-73. doi:
10.1007/s00347-009-2048-4. [PMID: 19838711] - Ricardo Villa-Bellosta, Víctor Sorribas. Different effects of arsenate and phosphonoformate on P(i) transport adaptation in opossum kidney cells.
American journal of physiology. Cell physiology.
2009 Sep; 297(3):C516-25. doi:
10.1152/ajpcell.00186.2009. [PMID: 19553564] - Karen Yao, Christel Hoest, Farzin Rashti, Timm C Schott, Steven Jacobson. Effect of (r)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine (H2G) and AZT-lipid-PFA on human herpesvirus-6B infected cells.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.
2009 Sep; 46(1):10-4. doi:
10.1016/j.jcv.2009.05.014. [PMID: 19524486] - Magdalena Brzozowska, Benjamin P Oberts, Gary J Blanchard, Jaroslaw Majewski, Pawel Krysinski. Design and characterization of novel tether layer for coupling of a bilayer lipid membrane to the surface of gold.
Langmuir : the ACS journal of surfaces and colloids.
2009 Aug; 25(16):9337-45. doi:
10.1021/la900739v. [PMID: 19518134] - Manthena V S Varma, Bo Feng, R Scott Obach, Matthew D Troutman, Jonathan Chupka, Howard R Miller, Ayman El-Kattan. Physicochemical determinants of human renal clearance.
Journal of medicinal chemistry.
2009 Aug; 52(15):4844-52. doi:
10.1021/jm900403j. [PMID: 19445515] - Ting Zhou, Xi-Nan Cen, Zhi-Xiang Qiu, Jin-Ping Ou, Wen-Sheng Wang, Wei-Lin Xu, Yuan Li, Mang-Ju Wang, Li-Hong Wang, Yu-Jun Tong, Han-Yun Ren. [Clinical analysis of acute renal failure after allogeneic hematopoietic stem cell transplantation].
Zhongguo shi yan xue ye xue za zhi.
2009 Jun; 17(3):723-8. doi:
NULL. [PMID: 19549395] - Ricardo Villa-Bellosta, Victor Sorribas. On vascular calcification prevention with phosphonoformate and bisphosphonates.
Kidney international.
2009 06; 75(12):1355-1356. doi:
10.1038/ki.2009.108. [PMID: 19483753] - Muralikrishna Gopal, Archana Bhaskaran, Wissam I Khalife, Alejandro Barbagelata. Heart Disease in Patients with HIV/AIDS-An Emerging Clinical Problem.
Current cardiology reviews.
2009 May; 5(2):149-54. doi:
10.2174/157340309788166705. [PMID: 20436855]