N4-Acetylaminobutanal (BioDeep_00000006007)

 

Secondary id: BioDeep_00001869249

human metabolite Endogenous


代谢物信息卡片


N-Acetyl-4-aminobutanal

化学式: C6H11NO2 (129.079)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 7.81%

分子结构信息

SMILES: CC(=O)NCCCC=O
InChI: InChI=1S/C6H11NO2/c1-6(9)7-4-2-3-5-8/h5H,2-4H2,1H3,(H,7,9)

描述信息

N4-Acetylaminobutanal is an intermediate of the urea cycle and metabolism of amino groups, the product of the enzyme monoamine oxidase A [EC:1.4.3.4] and the substrate of the enzyme aldehyde dehydrogenase 2 family (mitochondrial) [EC:1.2.1.3].
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

5 个代谢物同义名

N-Acetyl-4-aminobutanal; N-(4-oxobutyl)acetamide; 4-(Acetylamino)butanal; N4-Acetylaminobutanal; 4-acetamidobutanal



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

7 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(4)

WikiPathways(1)

Plant Reactome(0)

INOH(1)

PlantCyc(0)

COVID-19 Disease Map(1)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 3 CASP3, EGFR, PIK3CA
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 1 EGFR
Nucleus 2 CASP3, EGFR
cytosol 2 CASP3, PIK3CA
nucleoplasm 1 CASP3
Cell membrane 2 EGFR, TNF
lamellipodium 1 PIK3CA
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
cell junction 1 EGFR
cell surface 2 EGFR, TNF
glutamatergic synapse 2 CASP3, EGFR
Golgi membrane 1 EGFR
lysosomal membrane 1 GAA
neuronal cell body 2 CASP3, TNF
Lysosome 1 GAA
endosome 1 EGFR
plasma membrane 4 EGFR, GAA, PIK3CA, TNF
Membrane 2 EGFR, GAA
apical plasma membrane 1 EGFR
basolateral plasma membrane 1 EGFR
extracellular exosome 2 GAA, MMP9
Lysosome membrane 1 GAA
extracellular space 3 EGFR, MMP9, TNF
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 2 EGFR, PIK3CA
intercalated disc 1 PIK3CA
protein-containing complex 1 EGFR
intracellular membrane-bounded organelle 1 GAA
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 EGFR
Secreted 1 GAA
extracellular region 3 GAA, MMP9, TNF
nuclear membrane 1 EGFR
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 1 MMP9
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 2 EGFR, TNF
focal adhesion 1 EGFR
intracellular vesicle 1 EGFR
collagen-containing extracellular matrix 1 MMP9
receptor complex 1 EGFR
phagocytic cup 1 TNF
tertiary granule membrane 1 GAA
basal plasma membrane 1 EGFR
synaptic membrane 1 EGFR
ficolin-1-rich granule lumen 1 MMP9
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
tertiary granule lumen 1 MMP9
azurophil granule membrane 1 GAA
clathrin-coated endocytic vesicle membrane 1 EGFR
ficolin-1-rich granule membrane 1 GAA
death-inducing signaling complex 1 CASP3
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
autolysosome lumen 1 GAA
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Louis M T Bradbury, Susan A Gillies, Donald J Brushett, Daniel L E Waters, Robert J Henry. Inactivation of an aminoaldehyde dehydrogenase is responsible for fragrance in rice. Plant molecular biology. 2008 Nov; 68(4-5):439-49. doi: 10.1007/s11103-008-9381-x. [PMID: 18704694]