Dichloromethane (BioDeep_00000004889)

 

Secondary id: BioDeep_00000868792, BioDeep_00001867640

human metabolite Endogenous


代谢物信息卡片


Dichloride, methylene

化学式: CH2Cl2 (83.9533552)
中文名称: 二氯甲烷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(Cl)Cl
InChI: InChI=1S/CH2Cl2/c2-1-3/h1H2

描述信息

Dichloromethane is used as an extraction solvent in the preparation of decaffeinated coffee, hop extracts and spice oleoresins. Diluent for colour additives and inks for marking fruit and vegetables The output of these processes is a mixture of methyl chloride, dichloromethane, chloroform, and carbon tetrachloride. These compounds are separated by distillation

同义名列表

30 个代谢物同义名

Dichloride, methylene; Chlorure de methylene; Bichloride, methylene; Methylene dichloride; Dichloromethane, acs; Methylene bichloride; Dichloromethane, NF; Chloride, methylene; Methane dichloride; Methylene chloride; Dichloro-methane; Metylenu chlorek; DICHLOROMETHANE; Methylenchlorid; Distillex DS3; Dichlormethan; Aerothene MM; Solmethine; Methoklone; Solaesthin; m-Clean D; Salesthin; Aerothene; Driverit; Narkotil; Freon 30; Nevolin; CH2CL2; R 30; DCM



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

7 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Melissa G Morais, Aline A Saldanha, Iara C Mendes, João Paulo C Rodrigues, Lucas S Azevedo, Letícia M Ferreira, Paula A Amado, Vanessa S S Zanuncio, Katyuce S Farias, Denise B Silva, Flávia C H Pinto, Adriana C Soares, Luciana A R S Lima. Antinociceptive and anti-inflammatory potential, and chemical characterization of the dichloromethane fraction of Solanum lycocarpum (Solanaceae) ripe fruits by LC-DAD-MS. Journal of ethnopharmacology. 2024 Mar; 322(?):117640. doi: 10.1016/j.jep.2023.117640. [PMID: 38135235]
  • Khawlah Shari, Osama G Mohamed, Khaled M Meselhy, Ashootosh Tripathi, Amal E Khaleel, Essam Abdel-Sattar, Rania A El Gedaily. Cytotoxic and antiviral activities of Jatropha variegata and Jatropha spinosa in relation to their metabolite profile. Scientific reports. 2024 02; 14(1):4846. doi: 10.1038/s41598-024-55196-1. [PMID: 38418513]
  • Jimena Borgo, Mariel S Wagner, Laura C Laurella, Orlando G Elso, Mariana G Selener, María Clavin, Hernán Bach, César A N Catalán, Augusto E Bivona, Claudia S Sepúlveda, Valeria P Sülsen. Plant Extracts and Phytochemicals from the Asteraceae Family with Antiviral Properties. Molecules (Basel, Switzerland). 2024 Feb; 29(4):. doi: 10.3390/molecules29040814. [PMID: 38398567]
  • Abdirahman Elmi, A Said Mohamed, Ali Mérito, Sébastien Charneau, Mohamed Amina, Philippe Grellier, Mohammed Bouachrine, Ata M Lawson, Fatouma M Abdoul-Latif, Maha A Y Kordofani. The ethnopharmacological study of plant drugs used traditionally in Djibouti for malaria treatment. Journal of ethnopharmacology. 2024 Feb; ?(?):117839. doi: 10.1016/j.jep.2024.117839. [PMID: 38310984]
  • Salima Haddou, Amal Elrherabi, El Hassania Loukili, Rhizlan Abdnim, Asmae Hbika, Mohamed Bouhrim, Omkulthom Al Kamaly, Asmaa Saleh, Abdelaaty A Shahat, Mohamed Bnouham, Belkheir Hammouti, Abdelkrim Chahine. Chemical Analysis of the Antihyperglycemic, and Pancreatic α-Amylase, Lipase, and Intestinal α-Glucosidase Inhibitory Activities of Cannabis sativa L. Seed Extracts. Molecules (Basel, Switzerland). 2023 Dec; 29(1):. doi: 10.3390/molecules29010093. [PMID: 38202676]
  • Andreja Komnenić, Zorica Lazarević, Zoran Jovović, Katarina Šavikin, Dejan Pljevljakušić. Multiple liquid-liquid extraction of dissolved compounds in immortelle hydrosol with four different solvents. Chemistry & biodiversity. 2023 Dec; ?(?):e202301528. doi: 10.1002/cbdv.202301528. [PMID: 38116850]
  • Peng Zhang, Xiaoou Ma, Qian Zhang, Ziyu Guo, Junyi Hao, Zhixuan Zhang, Ming Sun, Yan Liu. Determination of Volatile Organic Compounds and Endogenous Extracts and Study of Expression Patterns of TPS and BSMT in the Flowers of Seven Lilium Cultivars. Molecules (Basel, Switzerland). 2023 Dec; 28(24):. doi: 10.3390/molecules28247938. [PMID: 38138428]
  • W M Al-Madhagi, O Sharhan, B Jadan, N M Hashim, N Awadh, R Othman. New peperomin and polyketides from dichloromethane extract of Peperomia blanda Jack. (Kunth). Tropical biomedicine. 2023 Dec; 40(4):486-496. doi: 10.47665/tb.40.4.015. [PMID: 38308837]
  • Hafize Yuca, Mehmet Karadayı, Songül Karakaya, Ayşe Civaş, Enes Tekman, Zuhal Guvenalp. Phytochemical Analysis and Evaluation of Genotoxic, Antigenotoxic Effects in Bacterial Models, and Hypoglycemic Activity of Epilobium angustifolium L. with Bioguided Isolation of Active Compounds. Chemistry & biodiversity. 2023 Dec; 20(12):e202300922. doi: 10.1002/cbdv.202300922. [PMID: 37997279]
  • Margarita Aguilar-Espinosa, José Enrique Ek-Ku, Renata Rivera-Madrid, Marina Vera-Ku. Advancing carotenoid Quantification: A new method for semi-quantitative assessment of β -Carotene and lycopene content in food extracts. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2023 Dec; 1231(?):123929. doi: 10.1016/j.jchromb.2023.123929. [PMID: 38035540]
  • Gustavo Galo Marcheafave, Elis Daiane Pauli, Cláudia Domiciano Tormena, Leonardo José Duarte, Ivar Wendling, Miroslava Rakocevic, Amanda Lemos Quintela, Maria de Fátima Costa Santos, Cláudio Francisco Tormena, Ieda Spacino Scarminio, Roy Edward Bruns. 1H NMR Mixture Design-Fingerprints and ASCA Analysis in Ilex paraguariensis: Model Stability in Search of a Global Metabolome. Analytical chemistry. 2023 11; 95(46):16850-16860. doi: 10.1021/acs.analchem.3c02592. [PMID: 37947492]
  • Rana M Ibrahim, Passent M Abdel-Baki, Ghada F Elmasry, Ahmed A El-Rashedy, Nariman E Mahdy. Combinative effects of akarkara root-derived metabolites on anti-inflammatory and anti-alzheimer key enzymes: integrating bioassay-guided fractionation, GC-MS analysis, and in silico studies. BMC complementary medicine and therapies. 2023 Nov; 23(1):413. doi: 10.1186/s12906-023-04210-6. [PMID: 37978514]
  • Mst Suraiya Khatun, Nuhu Mia, Mahci Al Bashera, Murshadul Alam Murad, Ronok Zahan, Shumaia Parvin, Most Afia Akhtar. Evaluation of anti-inflammatory potential and GC-MS profiling of leaf extracts from Clerodendrum infortunatum L. Journal of ethnopharmacology. 2023 Nov; ?(?):117366. doi: 10.1016/j.jep.2023.117366. [PMID: 37944873]
  • Aya S ElNagar, Mohamed M Mohyeldin, Nada M Mostafa, Sherihan Salaheldin Abdelhamid Ibrahim, Gaber El-Saber Batiha, Mohamed H Mahmoud, Lucian Hritcu, Omayma A Eldahshan. Antioxidant and anti-Alzheimer activities of Clivia miniata (Lindl) roots, bulbs, and aerial parts: In-vitro and in-silico studies. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Sep; 167(?):115382. doi: 10.1016/j.biopha.2023.115382. [PMID: 37778271]
  • Hong-Fei Shi, Bo-Peng Xu, Cheng-Xin Xu, Xiu-Qi Zhou, Hong-Fu Xu. [Rapid extraction and detection of five alkaloids in dried khat by solvent extraction-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry]. Se pu = Chinese journal of chromatography. 2023 Sep; 41(9):771-780. doi: 10.3724/sp.j.1123.2023.03009. [PMID: 37712541]
  • Shuang Yu, Yuan Gao, Xiu-Hua Zhu, Ning-Bo Geng, Yu-Bing Dai, Jian-Yao Hong, Ji-Ping Chen. [Determination of short- and medium-chain chlorinated paraffins in different components of human blood using gas chromatography-electron capture negative ion-low resolution mass spectrometry]. Se pu = Chinese journal of chromatography. 2023 Aug; 41(8):698-706. doi: 10.3724/sp.j.1123.2022.11012. [PMID: 37534557]
  • Louise Merquiol, Giovanna Romano, Adele Cutignano, Isabella D'Ambra. Chemical markers in marine food web: A simple workflow based on methyl tert-butyl ether extraction for fatty acids and stable isotopes assessment in plankton samples. Marine environmental research. 2023 Jul; 190(?):106087. doi: 10.1016/j.marenvres.2023.106087. [PMID: 37473598]
  • Tuba Aydin, Ruya Saglamtas, Mehmet Gumustas, Mucip Genisel, Cavit Kazaz, Ahmet Cakir. Lavandula stoechas L. subsp. stoechas, a New Herbal Source for Ursolic Acid: Quantitative Analysis, Purification and Bioactivity Studies. Chemistry & biodiversity. 2023 Jun; ?(?):e202300414. doi: 10.1002/cbdv.202300414. [PMID: 37338138]
  • Truong Quynh Nhu, Hang Bui Thi Bich, Huong Do Thi Thanh, Marie-Louise Scippo, Phuong Nguyen Thanh, Joëlle Quetin-Leclercq, Patrick Kestemont. Psidium guajava L.- dichloromethane and ethyl acetate fractions ameliorate striped catfish (Pangasianodon hypophthalmus) status via immune response, inflammatory, and apoptosis pathways. Fish & shellfish immunology. 2023 May; ?(?):108851. doi: 10.1016/j.fsi.2023.108851. [PMID: 37245678]
  • Rafael Short Ferreira, Paulo Roberto Ribeiro, Juliana Helena Castro E Silva, Juliana Bender Hoppe, Monique Marylin Alves de Almeida, Beatriz Correia de Lima Ferreira, Gustavo Borges Andrade, Suzana Braga de Souza, Luzimar Gonzaga Ferdandez, Maria de Fátima Dias Costa, Christianne Gazzana Salbego, Andrea Domenico Rivera, Aline Longoni, Adriano Martimbianco de Assis, Francesca Pieropan, José Cláudio Fonseca Moreira, Silvia Lima Costa, Arthur Morgan Butt, Victor Diogenes Amaral da Silva. Amburana cearensis seed extract stimulates astrocyte glutamate homeostatic mechanisms in hippocampal brain slices and protects oligodendrocytes against ischemia. BMC complementary medicine and therapies. 2023 May; 23(1):154. doi: 10.1186/s12906-023-03959-0. [PMID: 37170258]
  • Manal M Sabry, Rehab F Abdel-Rahman, Hany M Fayed, Azza T Taher, Hanan A Ogaly, Amgad Albohy, Sabah H El-Gayed, Rana M Ibrahim. Impact of Eucalyptus maculata Hook resin exudate constituents on reducing COX-2 gene expression: In-vivo anti-inflammatory, molecular docking and dynamics studies. Journal of ethnopharmacology. 2023 May; 314(?):116631. doi: 10.1016/j.jep.2023.116631. [PMID: 37172920]
  • Haleh Forouhandeh, Vahideh Tarhriz, Masoumeh Zadehkamand, Parina Asgharian. Anti-proliferative activity of Artemisia marschalliana on cancerous cell lines. BMC complementary medicine and therapies. 2023 Apr; 23(1):119. doi: 10.1186/s12906-023-03887-z. [PMID: 37059982]
  • Lian-Chun Li, Yu-Xia Fu, De-Sheng Ning, Ling-Ling Yu, Zhi-Qi Zou, Zheng-Hong Pan. The dichloromethane extract of Callicarpa longissima rich in diterpenoid phenols exerts anti-inflammatory effect via inhibiting the TLR4/NF-κB signaling pathway. Journal of ethnopharmacology. 2023 Apr; 305(?):116124. doi: 10.1016/j.jep.2022.116124. [PMID: 36587880]
  • Laura C Laurella, Orlando G Elso, Rachel Nápoles Rodriguez, Juan M Viecenz, María Rosario Alonso, Esteban J Bontempi, Emilio Malchiodi, Cesar A N Catalán, Silvia I Cazorla, Valeria P Sülsen. Antiprotozoal compounds from Mikania periplocifolia. Fitoterapia. 2023 Apr; ?(?):105499. doi: 10.1016/j.fitote.2023.105499. [PMID: 37019368]
  • Pitsinee Inthi, Hataichanok Pandith, Prachya Kongtawelert, Ratana Banjerdpongchai. Anti-cancer Effect and Active Phytochemicals of Houttuynia cordata Thunb. against Human Breast Cancer Cells. Asian Pacific journal of cancer prevention : APJCP. 2023 Apr; 24(4):1265-1274. doi: 10.31557/apjcp.2023.24.4.1265. [PMID: 37116149]
  • Teresa Pirker, Eva-Maria Pferschy-Wenzig, Evangelia Bampali, Valery Bochkov, Rudolf Bauer. Glycolipid-enriched fraction of Osmanthus fragrans inhibits LPS-induced expression of inflammatory genes, COX-2, E-selectin, and Interleukin-8. Journal of ethnopharmacology. 2023 Mar; ?(?):116328. doi: 10.1016/j.jep.2023.116328. [PMID: 36870464]
  • Md Ariful Islam, Sania Ashrafi, Khondaker Miraz Rahman, Shamim Ahmed, A H M Shofiul Islam Molla Jamal, Monira Ahsan. Isolation and Characterization of One New Natural Compound with Other Potential Bioactive Secondary Metabolites from Glycosmis cyanocarpa (Blume) Spreng. (Family: Rutaceae). Molecules (Basel, Switzerland). 2023 Feb; 28(5):. doi: 10.3390/molecules28052207. [PMID: 36903452]
  • Wafaa H B Hassan, Zeinab I El Sayed, Lamya H Al-Wahaibi, Mahmoud M Abdel-Aal, Wael M Abdel-Mageed, Eman Abdelsalam, Sahar Abdelaziz. Metabolites Profiling and In Vitro Biological Characterization of Different Fractions of Cliona sp. Marine Sponge from the Red Sea Egypt. Molecules (Basel, Switzerland). 2023 Feb; 28(4):. doi: 10.3390/molecules28041643. [PMID: 36838631]
  • Chen Jin, Ling Zhang, Cheng-Jun Yuan, Yi Liu, Hui-Zhen Liu, Bo-Lun Xu, Ji-Cheng Shu, Xiao-Yu Zhang, Si-Yi Wang, Hui-Lian Huang. New compounds from the stems of Fissistigma acuminatissimum Merr. and their in vitro anti-inflammatory activity. Natural product research. 2023 Feb; 37(4):551-559. doi: 10.1080/14786419.2022.2076231. [PMID: 35574640]
  • Xiaoling Yu, Tongchun Su, Bing Liu. Two new triterpenoids preventing the hydrocortisone-induced injury in HMEC-1 cells from Momordica charantia L. Natural product research. 2023 Feb; 37(4):663-668. doi: 10.1080/14786419.2022.2075863. [PMID: 35546104]
  • Xia'nan Sang, Xuedong Wan, Han Zhang, Jialiang Ying, Lu Wang, Qiao Yang, Qiyuan Shan, Min Hao, Minjing Qin, Qitong Zheng, Quan Chen, Xin Han, Gang Cao. The most bioactive fraction of stir-fried Radix Paeoniae Alba regulating IL-6/STAT3 signaling pathway in allergic asthma mouse. Journal of ethnopharmacology. 2023 Jan; 301(?):115821. doi: 10.1016/j.jep.2022.115821. [PMID: 36220510]
  • M Madiba, B B Oluremi, Z Gulube, O O Oderinlo, M Marimani, P M Osamudiamen, M Patel. Anti-Streptococcus mutans, anti-adherence and anti-acidogenic activity of Uvaria chamae P. Beauv. Journal of ethnopharmacology. 2023 Jan; 300(?):115673. doi: 10.1016/j.jep.2022.115673. [PMID: 36096348]
  • Lucía Bada, Renato B Pereira, David M Pereira, Marta Lores, María Celeiro, Elías Quezada, Eugenio Uriarte, José Gil-Longo, Dolores Viña. Phytochemical Analysis and Antiproliferative Activity of Ulex gallii Planch. (Fabaceae), a Medicinal Plant from Galicia (Spain). Molecules (Basel, Switzerland). 2023 Jan; 28(1):. doi: 10.3390/molecules28010351. [PMID: 36615543]
  • Bethel Kwansa-Bentum, Beatrice Awuradwoa Okine, Alberta D Dayie, Patience B Tetteh-Quarcoo, Fleischer C N Kotey, Eric S Donkor, Nicholas T K D Dayie. In Vitro effects of petroleum ether, dichloromethane, methanolic and aqueous leaf extracts of Eucalyptus grandis on selected multidrug-resistant bacteria. PloS one. 2023; 18(3):e0283706. doi: 10.1371/journal.pone.0283706. [PMID: 36996141]
  • S N Abd El-Rahmana, S A Abubshaitb, H A Abubshaitc, A M Elsharifb, M Kamound. The anti-aging, anti-tuberculosis and antioxidant potential benefits of Saudi Arabia Olea-Europaea Leaves extracts. Brazilian journal of biology = Revista brasleira de biologia. 2023; 84(?):e270885. doi: 10.1590/1519-6984.270885. [PMID: 37132677]
  • Vincenzo Musolino, Mariangela Marrelli, Maria Rosaria Perri, Martina Palermo, Micaela Gliozzi, Vincenzo Mollace, Filomena Conforti. Centranthus ruber (L.) DC. and Tropaeolum majus L.: Phytochemical Profile, In Vitro Anti-Denaturation Effects and Lipase Inhibitory Activity of Two Ornamental Plants Traditionally Used as Herbal Remedies. Molecules (Basel, Switzerland). 2022 Dec; 28(1):. doi: 10.3390/molecules28010032. [PMID: 36615228]
  • Othman Al Musaimi, Varshitha Gavva, Daryl R Williams. Greener Cleavage of Protected Peptide Fragments from Sieber Amide Resin. ChemistryOpen. 2022 12; 11(12):e202200236. doi: 10.1002/open.202200236. [PMID: 36564351]
  • Yaraset López-Lorenzo, María Elena Sánchez-Mendoza, Daniel Arrieta-Baez, Adriana Guadalupe Perez-Ruiz, Jesús Arrieta. Gastroprotective activity of (E)-ethyl-12-cyclohexyl-4,5-dihydroxydodec-2-enoate, a compound isolated from Heliotropium indicum: role of nitric oxide, prostaglandins, and sulfhydryls in its mechanism of action. Pharmaceutical biology. 2022 Dec; 60(1):1207-1213. doi: 10.1080/13880209.2022.2087690. [PMID: 35764528]
  • S Rahamouz-Haghighi, Kh Bagheri, N Mohsen-Pour, A Sharafi. in vitro Evaluation of Cytotoxicity and Antibacterial Activities of Ribwort Plantain (Plantago Lanceolata L.) Root Fractions and Phytochemical Analysis by Gas Chromatography-Mass Spectrometry. Archives of Razi Institute. 2022 12; 77(6):2131-2143. doi: 10.22092/ari.2022.358045.2143. [PMID: 37274901]
  • J Mcebisi Mabuza, Marcel Kaiser, M Johanna Bapela. In vitro antiplasmodial activity and cytotoxicity of extracts and chromatographic fractions of twigs from Pappea capensis EckI & Zeyh. (Sapindaceae). Journal of ethnopharmacology. 2022 Nov; 298(?):115659. doi: 10.1016/j.jep.2022.115659. [PMID: 36041692]
  • Angela Ethelis Jimenez Martinez, Sandro Froehner, Daniel Macedo Neto, Carlos Eduardo Galoski. Detailing the organic matter in suspended sediments as a tool to assess the impact of land occupation in water bodies: a case of Barigui Watershed (Southern Brazil). Environmental geochemistry and health. 2022 Nov; 44(11):4141-4156. doi: 10.1007/s10653-021-01167-8. [PMID: 35022876]
  • Noor Zafirah Ismail, Salwani Md Saad, Ismail Abiola Adebayo, Zaleha Md Toha, Rafedah Abas, Nur Nadhirah Mohamad Zain, Hasni Arsad. The antiproliferative and apoptotic potential of Clinacanthus nutans against human breast cancer cells through targeted apoptosis pathway. Environmental science and pollution research international. 2022 Nov; 29(54):81685-81702. doi: 10.1007/s11356-022-20858-y. [PMID: 35737268]
  • Never Zekeya, Bertha Mamiro, Humphrey Ndossi, Rehema Chande Mallya, Mhuji Kilonzo, Alex Kisingo, Mkumbukwa Mtambo, Jafari Kideghesho, Jaffu Chilongola. Screening and evaluation of cytotoxicity and antiviral effects of secondary metabolites from water extracts of Bersama abyssinica against SARS-CoV-2 Delta. BMC complementary medicine and therapies. 2022 Oct; 22(1):280. doi: 10.1186/s12906-022-03754-3. [PMID: 36289484]
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  • Luísa Nathália Bolda Mariano, Daiane Aline Pontioli, Ana Aline da Silva, Rivaldo Niero, Valdir Cechinel-Filho, Priscila de Souza. Diuretic and Antiurolithic Effect of Garcinia humilis (Vahl) C.D. Adams Leaves, a Medicinal Plant Native to South American Countries. Chemistry & biodiversity. 2022 Oct; 19(10):e202200022. doi: 10.1002/cbdv.202200022. [PMID: 35997661]
  • Madison Patrick, Yilue Zhang, Angela I Calderón. Combination of HRLC-MS with MPP and GNPS data analysis to identify major constituents of MtSK inhibitory Alpinia galanga extract. Natural product research. 2022 Oct; 36(19):5064-5068. doi: 10.1080/14786419.2021.1916015. [PMID: 33951985]
  • Le Canh Viet Cuong, Nguyen Phuc Khanh Nhi, Tran Phuong Ha, Le Tuan Anh, Ton That Huu Dat, Phung Thi Thuy Oanh, Nguyen Thi Minh Phuong, Vo Thi Kim Thu, Ho Viet Duc, Hoang Le Tuan Anh. A new steroidal saponin from the aerial parts of Solanum torvum. Natural product research. 2022 Oct; 36(19):4892-4897. doi: 10.1080/14786419.2021.1908282. [PMID: 33813958]
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