rifamycin B (BioDeep_00000004772)
代谢物信息卡片
化学式: C39H49NO14 (755.3153)
中文名称: 利福霉素B
谱图信息:
最多检出来源 Macaca mulatta(otcml) 66.04%
分子结构信息
SMILES: C12=C3C(=CC(=C1O)NC(=O)C(=CC=C[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@H]([C@H](OC(=O)C)[C@H](C)[C@@H](OC)C=CO[C@]1(C)C(C3=C(C(C)=C2O)O1)=O)C)C)OCC(=O)O
InChI: InChI=1S/C39H49NO14/c1-17-11-10-12-18(2)38(49)40-24-15-26(51-16-27(42)43)28-29(34(24)47)33(46)22(6)36-30(28)37(48)39(8,54-36)52-14-13-25(50-9)19(3)35(53-23(7)41)21(5)32(45)20(4)31(17)44/h10-15,17,19-21,25,31-32,35,44-47H,16H2,1-9H3,(H,40,49)(H,42,43)/b11-10+,14-13+,18-12-/t17-,19+,20+,21+,25-,31-,32+,35+,39-/m0/s1
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D012294 - Rifamycins
同义名列表
3 个代谢物同义名
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:17876
- KEGG: C01848
- PubChem: 5459948
- PubChem: 26340
- Metlin: METLIN40965
- LipidMAPS: LMPK05000003
- CAS: 13929-35-6
- PMhub: MS000017365
- MetaboLights: MTBLC17876
- PubChem: 4965
- 3DMET: B01506
- NIKKAJI: J14.966G
- KNApSAcK: 17876
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Feifei Qi, Chao Lei, Fengwei Li, Xingwang Zhang, Jin Wang, Wei Zhang, Zhen Fan, Weichao Li, Gong-Li Tang, Youli Xiao, Guoping Zhao, Shengying Li. Deciphering the late steps of rifamycin biosynthesis.
Nature communications.
2018 06; 9(1):2342. doi:
10.1038/s41467-018-04772-x. [PMID: 29904078] - Chao Lei, Jingzhi Wang, Yuanyuan Liu, Xinqiang Liu, Guoping Zhao, Jin Wang. A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei.
Microbial cell factories.
2018 Jan; 17(1):14. doi:
10.1186/s12934-018-0863-5. [PMID: 29375035] - Hua Yuan, Wei Zhao, Yi Zhong, Jin Wang, Zhongjun Qin, Xiaoming Ding, Guo-Ping Zhao. Two genes, rif15 and rif16, of the rifamycin biosynthetic gene cluster in Amycolatopsis mediterranei likely encode a transketolase and a P450 monooxygenase, respectively, both essential for the conversion of rifamycin SV into B.
Acta biochimica et biophysica Sinica.
2011 Dec; 43(12):948-56. doi:
10.1093/abbs/gmr091. [PMID: 21986914] - L M Kuz'mina, T P Krasnova, A V Lysko, V N Vostrikova, A E Rychkov, N A Kolesnikova, N I Mal'tsev. [Method for developing a controlled process. Study of the possible regulation of rifamycin B biosynthesis].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic].
1990 Jul; 35(7):5-8. doi:
. [PMID: 2285341] - L M Kuz'mina, T P Krasnova, A V Lysko, V N Vostrikova, O A Bushueva, N I Mal'tsev. [A method for developing a controlled process. Development and execution of a program supplying culture medium components for rifamycin B biosynthesis].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic].
1990 Jul; 35(7):8-12. doi:
. [PMID: 2285343] - S Tsuji, K Nakagawa, T Fukushima. Genetically controlled quantitative variation of ornithine transcarbamylase in the chick kidney.
Biochemical genetics.
1983 Oct; 21(9-10):857-69. doi:
10.1007/bf00483945. [PMID: 6419722] - M Sano. Subcellular localizations of guanylate cyclase and 3',5'-cyclic nucleotide phosphodiesterase in sea urchin sperm.
Biochimica et biophysica acta.
1976 Apr; 428(2):525-31. doi:
10.1016/0304-4165(76)90061-1. [PMID: 6049] - H H Borden, R W Harris, W E Mosher. A waterborne outbreak of gastroenteritis in western New York State.
American journal of public health and the nation's health.
1970 Feb; 60(2):283-8. doi:
10.2105/ajph.60.2.283. [PMID: 5460971]
