Viomycin (BioDeep_00000004707)

   


代谢物信息卡片


Tuberactinomycin B; Vinacetin A; Vioactane

化学式: C25H43N13O10 (685.3256)
中文名称: 紫霉素
谱图信息: 最多检出来源 Mus musculus(plant) 2.47%

分子结构信息

SMILES: C(C[C@@H](CC(=O)N[C@H]1CNC(=O)[C@H]([C@H]2C[C@@H](NC(=N)N2)O)NC(=O)/C(=C/NC(=O)N)/NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC1=O)N)CN
InChI: InChI=1S/C25H43N13O10/c26-3-1-2-10(27)4-16(41)32-12-6-30-23(47)18(11-5-17(42)37-24(28)36-11)38-20(44)13(7-31-25(29)48)33-21(45)14(8-39)35-22(46)15(9-40)34-19(12)43/h7,10-12,14-15,17-18,39-40,42H,1-6,8-9,26-27H2,(H,30,47)(H,32,41)(H,33,45)(H,34,43)(H,35,46)(H,38,44)(H3,28,36,37)(H3,29,31,48)/b13-7-/t10-,11+,12-,14-,15-,17-,18-/m0/s1

描述信息

A cyclic peptide antibiotic produced by the actinomycete Streptomyces puniceus, used in the treatment of tuberculosis.
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D000995 - Antitubercular Agents
C254 - Anti-Infective Agent > C52588 - Antibacterial Agent > C280 - Antitubercular Agent
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors

同义名列表

3 个代谢物同义名

Viomycin; Tuberactinomycin B; Vinacetin A; Vioactane; Viomycin



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ALB, CAT, CELF2, FTO, GRK5, LEF1, RPL27, SCP2, TUBB4B, TYR
Peripheral membrane protein 1 GUF1
Nucleus 9 ALB, CELF2, FTO, LEF1, MYB, PANK2, RPL27, SCP2, TUBB4B
cytosol 9 ALB, CAT, FTO, GRK5, MYB, PANK2, RPL27, SCP2, TUBB4B
centrosome 1 ALB
nucleoplasm 7 ATP2B1, CELF2, FTO, LEF1, MYB, RPL27, SCP2
RNA polymerase II transcription regulator complex 1 MYB
Cell membrane 1 ATP2B1
Multi-pass membrane protein 2 ATP2B1, CACNA1E
Synapse 3 ATP2B1, CACNA1E, RPL27
cell surface 2 AMELX, TNR
glutamatergic synapse 2 ATP2B1, TNR
Golgi apparatus 1 ALB
mitochondrial inner membrane 1 GUF1
neuronal cell body 2 CACNA1E, INHA
presynaptic membrane 1 ATP2B1
Cytoplasm, cytosol 1 RPL27
Lysosome 1 TYR
endosome 1 UEVLD
plasma membrane 4 ATP2B1, CACNA1E, FTO, GRK5
synaptic vesicle membrane 1 ATP2B1
Membrane 7 ATP2B1, CACNA1E, CAT, MYB, PANK2, RPL27, SCP2
basolateral plasma membrane 1 ATP2B1
extracellular exosome 7 ALB, ATP2B1, CAT, RPL27, SPINK1, TUBB4B, UEVLD
endoplasmic reticulum 3 ALB, RPL27, SCP2
extracellular space 3 ALB, INHA, TNR
perinuclear region of cytoplasm 1 TYR
Schaffer collateral - CA1 synapse 1 TNR
mitochondrion 4 CAT, GUF1, PANK2, SCP2
protein-containing complex 3 ALB, CAT, SCP2
intracellular membrane-bounded organelle 5 ATP2B1, CAT, CELF2, FTO, TYR
Single-pass type I membrane protein 1 TYR
Secreted 3 ALB, INHA, SPINK1
extracellular region 6 ALB, AMELX, CAT, INHA, TNR, TUBB4B
mitochondrial matrix 2 CAT, GUF1
anchoring junction 1 ALB
transcription regulator complex 1 LEF1
photoreceptor inner segment 1 INHA
photoreceptor outer segment 1 INHA
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
nuclear membrane 1 GRK5
Extracellular vesicle 1 TUBB4B
Secreted, extracellular space, extracellular matrix 2 AMELX, TNR
microtubule cytoskeleton 1 TUBB4B
nucleolus 1 RPL27
Melanosome membrane 1 TYR
Golgi-associated vesicle 1 TYR
Mitochondrion inner membrane 1 GUF1
Matrix side 1 GUF1
Membrane raft 1 TNR
Cytoplasm, cytoskeleton 1 TUBB4B
focal adhesion 2 CAT, RPL27
microtubule 1 TUBB4B
Peroxisome 2 CAT, SCP2
Peroxisome matrix 1 CAT
peroxisomal matrix 2 CAT, SCP2
peroxisomal membrane 1 CAT
Mitochondrion intermembrane space 1 PANK2
mitochondrial intermembrane space 1 PANK2
collagen-containing extracellular matrix 2 AMELX, TNR
lateral plasma membrane 1 ATP2B1
nuclear speck 2 FTO, GRK5
ciliary basal body 1 ALB
chromatin 1 LEF1
cell projection 1 ATP2B1
mitotic spindle 1 TUBB4B
Chromosome 1 SCP2
cytoskeleton 1 TUBB4B
centriole 1 ALB
Flemming body 1 CELF2
[Isoform 1]: Mitochondrion 1 PANK2
inhibin A complex 1 INHA
spindle pole 1 ALB
condensed chromosome, centromeric region 1 SCP2
blood microparticle 1 ALB
ESCRT I complex 1 UEVLD
Basolateral cell membrane 1 ATP2B1
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
axonemal microtubule 1 TUBB4B
lateral element 1 SCP2
monoatomic ion channel complex 1 CACNA1E
Melanosome 1 TYR
Nucleus speckle 1 FTO
Presynaptic cell membrane 1 ATP2B1
[Isoform 3]: Cytoplasm 1 PANK2
[Isoform 4]: Cytoplasm 1 PANK2
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 2 ALB, AMELX
nuclear matrix 1 MYB
platelet alpha granule lumen 1 ALB
voltage-gated calcium channel complex 1 CACNA1E
endocytic vesicle 1 AMELX
beta-catenin-TCF complex 1 LEF1
azurophil granule lumen 1 TUBB4B
immunological synapse 1 ATP2B1
perineuronal net 1 TNR
[Isoform 2]: Cytoplasm 1 PANK2
ribonucleoprotein complex 2 CELF2, RPL27
protein-DNA complex 1 LEF1
synaptonemal complex 1 SCP2
Rough endoplasmic reticulum 1 RPL27
cytosolic ribosome 1 RPL27
cytoplasmic side of rough endoplasmic reticulum membrane 1 RPL27
ribosome 1 RPL27
catalase complex 1 CAT
inhibin B complex 1 INHA
inhibin-betaglycan-ActRII complex 1 INHA
cytosolic large ribosomal subunit 1 RPL27
photoreceptor ribbon synapse 1 ATP2B1
tenascin complex 1 TNR
[Isoform SCP2]: Peroxisome 1 SCP2
[Isoform SCPx]: Peroxisome 1 SCP2
ciliary transition fiber 1 ALB


文献列表

  • L J Norcia, A M Silvia, J P Dirlam, R C Schnur, J M Bergeron, J A Retsema, S F Hayashi. In vitro microbiological characterization of novel cyclic homopentapeptides, CP-101,680 and CP-163,234, for animal health use. The Journal of antibiotics. 1999 Nov; 52(11):1007-16. doi: 10.7164/antibiotics.52.1007. [PMID: 10656573]
  • H Tanimori, T Kitagawa. A new liquid-phase enzyme immunoassay for rabbit IgM antibodies and its application for comparing the specificity of IgM and IgG antibodies contained in the same antiserum. Journal of immunological methods. 1990 May; 129(2):233-42. doi: 10.1016/0022-1759(90)90444-z. [PMID: 2161882]
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  • W Jao, J R Manaligod, L T Gerardo, M M Castillo. Myeloid bodies in drug-induced acute tubular necrosis. The Journal of pathology. 1983 Jan; 139(1):33-40. doi: 10.1002/path.1711390104. [PMID: 6298392]
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