(3S)-3,6-Diaminohexanoate (BioDeep_00000004589)

 

Secondary id: BioDeep_00001869921

human metabolite Endogenous


代谢物信息卡片


(3S)-3,6-Diaminohexanoic acid

化学式: C6H14N2O2 (146.1055)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(otcml) 22.23%

分子结构信息

SMILES: C(CC(CC(=O)O)N)CN
InChI: InChI=1S/C6H14N2O2/c7-3-1-2-5(8)4-6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m0/s1

描述信息

(3S)-3,6-Diaminohexanoate is found in the lysine degradation pathway. (3S)-3,6-Diaminohexanoate is created from L-lysine through the action of lysine 2,3-aminomutase [EC:5.4.3.2]. (3S)-3,6-Diaminohexanoate is then reversibly converted to (3S,5S)-3,5-Diaminohexanoate by beta-lysine 5,6-aminomutase [EC:5.4.3.3].
(3S)-3,6-Diaminohexanoate is found in the lysine degradation pathway.

同义名列表

12 个代谢物同义名

(3S)-3,6-Diaminohexanoic acid; (3S)-3,6-Diaminohexanoate; 3,6-diamino-Hexanoic acid; 3,6-Diaminohexanoic acid; beta-Lysine, (R)-isomer; beta-Lysine, (S)-isomer; 3,6-diamino-Hexanoate; 3,6-Diaminohexanoate; L-beta-Lysine; beta-Lysine; L-Β-lysine; L-b-Lysine



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 BPIFB3, CAT, DMD, EIF3K, EIF5A, KARS1, MMUT, MTR
Peripheral membrane protein 3 DMD, EIF5A, KARS1
Endoplasmic reticulum membrane 1 EIF5A
Nucleus 5 DMD, EIF3K, EIF5A, KARS1, YBEY
cytosol 8 CAT, DMD, EIF3K, EIF5A, GPT, KARS1, MTR, NAT1
nucleoplasm 2 ATP2B1, KARS1
Cell membrane 3 ATP2B1, KARS1, NAT1
Cytoplasmic side 2 DMD, EIF5A
Multi-pass membrane protein 2 ATP2B1, NAT1
Synapse 3 ATP2B1, DMD, NAT1
cell surface 2 DMD, NAT1
glutamatergic synapse 1 ATP2B1
presynaptic membrane 2 ATP2B1, NAT1
sarcolemma 1 DMD
plasma membrane 4 ATP2B1, DMD, KARS1, NAT1
synaptic vesicle membrane 2 ATP2B1, NAT1
Membrane 6 ATP2B1, CAT, DMD, EIF3K, EIF5A, NAT1
apical plasma membrane 1 NAT1
axon 1 NAT1
basolateral plasma membrane 2 ATP2B1, NAT1
extracellular exosome 5 ATP2B1, CAT, DEFA1, GPT, LYZ
extracellular space 6 BMP8B, DEFA1, IL6, INHBE, KARS1, LYZ
mitochondrion 4 CAT, KARS1, MMUT, YBEY
protein-containing complex 2 CAT, DMD
intracellular membrane-bounded organelle 2 ATP2B1, CAT
filopodium 1 DMD
Secreted 5 BMP8B, BPIFB3, IL6, INHBE, KARS1
extracellular region 5 BPIFB3, CAT, DEFA1, IL6, LYZ
neuronal cell body membrane 1 NAT1
Mitochondrion matrix 1 MMUT
mitochondrial matrix 3 CAT, KARS1, MMUT
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
Z disc 1 DMD
postsynaptic membrane 1 DMD
Cell membrane, sarcolemma 1 DMD
Membrane raft 1 DMD
Cytoplasm, cytoskeleton 1 DMD
focal adhesion 1 CAT
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 2 DEFA1, INHBE
lateral plasma membrane 1 ATP2B1
Nucleus outer membrane 1 DMD
nuclear outer membrane 1 DMD
Postsynaptic cell membrane 1 DMD
cell projection 1 ATP2B1
cytoskeleton 1 DMD
Basolateral cell membrane 2 ATP2B1, NAT1
nuclear pore 1 EIF5A
Presynaptic cell membrane 1 ATP2B1
filopodium membrane 1 DMD
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
Golgi lumen 1 DEFA1
endoplasmic reticulum lumen 1 IL6
eukaryotic 43S preinitiation complex 1 EIF3K
eukaryotic 48S preinitiation complex 1 EIF3K
eukaryotic translation initiation factor 3 complex 1 EIF3K
specific granule lumen 1 LYZ
tertiary granule lumen 1 LYZ
azurophil granule lumen 2 DEFA1, LYZ
immunological synapse 1 ATP2B1
Single-pass type IV membrane protein 1 DMD
annulate lamellae 1 EIF5A
costamere 1 DMD
aminoacyl-tRNA synthetase multienzyme complex 1 KARS1
dystrophin-associated glycoprotein complex 1 DMD
cell-substrate junction 1 DMD
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
[Isoform Mitochondrial]: Mitochondrion 1 KARS1
[Isoform Cytoplasmic]: Cytoplasm, cytosol 1 KARS1
neuron projection terminus 1 DMD
photoreceptor ribbon synapse 1 ATP2B1
syntrophin complex 1 DMD
organelle 1 DMD
plasma membrane bounded cell projection 1 DMD


文献列表

  • E S Kynina, A V Nikitin, S T Dziubak, V M Vitvitskiĭ, V V Viktorovskiĭ. [Use of antibiotics and their combinations with immunomodulators in treatment of experimental salmonellosis in albino rats]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 1993 Jul; 38(7):26-9. doi: NULL. [PMID: 8161272]
  • J Bíres, M Harvan, P Hudák, L Mucha, Z Juhásová. [The effect of Zindep inj. preparation on levels of zinc, T-lymphocytes and beta-lysine in the blood of pregnant dairy cows]. Veterinarni medicina. 1991 Nov; 36(11):641-8. doi: NULL. [PMID: 1841475]
  • Y Inamori, H Amino, M Tsuboi, S Yamaguchi, H Tsujibo. Biological activities of racemomycin-B, beta-lysine rich streptothricin antibiotic, the main component of Streptomyces lavendulae OP-2. Chemical & pharmaceutical bulletin. 1990 Aug; 38(8):2296-8. doi: 10.1248/cpb.38.2296. [PMID: 2177682]
  • A B Chemnyĭ, A I Smoliagin. [Various indices of immunity in patients with alcoholic delirium]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). 1986; 86(2):232-6. doi: NULL. [PMID: 3085414]
  • N I Balakliets, A Ia Tsyganenko. [Effect of benzylpenicillin and tetracycline on the phagocytic, nonspecific humoral and biochemical activity of uninfected animals]. Antibiotiki. 1984 May; 29(5):350-3. doi: . [PMID: 6204584]
  • S T Dziubak. [The effect of Pseudomonas aeruginosa exotoxin on various nonspecific factors of immunologic reactivity in an experiment]. Zhurnal mikrobiologii, epidemiologii i immunobiologii. 1983 Jun; ?(6):69-72. doi: NULL. [PMID: 6412491]
  • P V Baranovskii, N D Lobanova. [Content of serum lysozyme, beta-lysines and heterophilic antibodies in heart decompensation]. Laboratornoe delo. 1981; ?(12):750-1. doi: NULL. [PMID: 6172657]
  • O A Abdyldaev. [Certain problems of diagnosis and clinical course of nephroptosis]. Zdravookhranenie Kirgizii. 1975 Jul; ?(4):32-4. doi: NULL. [PMID: 1923]