Succinyl-CoA (BioDeep_00000004380)
Secondary id: BioDeep_00001868805
human metabolite PANOMIX_OTCML-2023 Endogenous
代谢物信息卡片
化学式: C25H40N7O19P3S (867.1312)
中文名称: 琥珀酰辅酶A
谱图信息:
最多检出来源 Homo sapiens(otcml) 8.86%
Last reviewed on 2024-09-14.
Cite this Page
Succinyl-CoA. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/succinyl-coa (retrieved
2024-12-27) (BioDeep RN: BioDeep_00000004380). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: CC(C)(COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)C(C(=O)NCCC(=O)NCCSC(=O)CCC(=O)O)O
InChI: InChI=1S/C25H40N7O19P3S/c1-25(2,20(38)23(39)28-6-5-14(33)27-7-8-55-16(36)4-3-15(34)35)10-48-54(45,46)51-53(43,44)47-9-13-19(50-52(40,41)42)18(37)24(49-13)32-12-31-17-21(26)29-11-30-22(17)32/h11-13,18-20,24,37-38H,3-10H2,1-2H3,(H,27,33)(H,28,39)(H,34,35)(H,43,44)(H,45,46)(H2,26,29,30)(H2,40,41,42)/t13-,18-,19-,20+,24-/m1/s1
描述信息
Succinyl-CoA is an important intermediate in the citric acid cycle, where it is synthesized from α-Ketoglutarate by α-ketoglutarate dehydrogenase (EC 1.2.4.2) through decarboxylation, and is converted into succinate through the hydrolytic release of coenzyme A by succinyl-CoA synthetase (EC 6.2.1.5). Succinyl-CoA may be an end product of peroxisomal beta-oxidation of dicarboxylic fatty acids; the identification of an apparently specific succinyl-CoA thioesterase (ACOT4, EC 3.1.2.3, hydrolyzes succinyl-CoA) in peroxisomes strongly suggests that succinyl-CoA is formed in peroxisomes. Acyl-CoA thioesterases (ACOTs) are a family of enzymes that catalyze the hydrolysis of the CoA esters of various lipids to the free acids and coenzyme A, thereby regulating levels of these compounds. (PMID: 16141203) [HMDB]. Succinyl-CoA is found in many foods, some of which are fruits, sea-buckthornberry, pomegranate, and sweet orange.
Succinyl-CoA is an important intermediate in the citric acid cycle, where it is synthesized from α-Ketoglutarate by α-ketoglutarate dehydrogenase (EC 1.2.4.2) through decarboxylation, and is converted into succinate through the hydrolytic release of coenzyme A by succinyl-CoA synthetase (EC 6.2.1.5). Succinyl-CoA may be an end product of peroxisomal beta-oxidation of dicarboxylic fatty acids; the identification of an apparently specific succinyl-CoA thioesterase (ACOT4, EC 3.1.2.3, hydrolyzes succinyl-CoA) in peroxisomes strongly suggests that succinyl-CoA is formed in peroxisomes. Acyl-CoA thioesterases (ACOTs) are a family of enzymes that catalyze the hydrolysis of the CoA esters of various lipids to the free acids and coenzyme A, thereby regulating levels of these compounds. (PMID: 16141203).
同义名列表
38 个代谢物同义名
4-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido}ethyl)sulfanyl]-4-oxobutanoic acid; 4-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]-4-oxobutanoic acid; coenzyme A, S-(Hydrogen butanedioic acid); coenzyme A, S-(Hydrogen butanedioate); S-(hydrogen butanedioate) Coenzyme A; S-(3-Carboxy-propionyl)-coenzym-a; Coenzyme A S-(hydrogen succinate); S-(3-Carboxypropionyl)-coenzyme A; S-(Hydrogen succinyl)coenzyme A; S-(hydrogen butanedioate) CoA; S-(hydrogen butanedioic acid; S-(3-Carboxy-propionyl)-CoA; CoA S-(hydrogen succinate); S-(Hydrogen succinyl)-CoA; S-(hydrogen butanedioate; succino-1-yl-coenzyme a; Coenzyme A S-succinate; succinyl-S-coenzyme-A; S-Succinoylcoenzyme A; succinyl-S-Coenzyme A; Succinyl-coenzyme A; Succinyl coenzyme A; succinylcoenzyme-A; succ-S-coenzyme-A; succ-S-Coenzyme A; CoA S-succinate; succ-Coenzyme A; succ-coenzyme-A; SCHEMBL4364428; succinyl-S-CoA; Succinyl CoA; Succinyl-CoA; succ-S-CoA; succ-CoA; suc-co-A; suc-coa; Succinyl-CoA; Succinyl-CoA
数据库引用编号
22 个数据库交叉引用编号
- ChEBI: CHEBI:15380
- KEGG: C00091
- PubChem: 439161
- PubChem: 92133
- PubChem: 1111
- HMDB: HMDB0001022
- Metlin: METLIN444
- DrugBank: DB03699
- Wikipedia: Succinyl-CoA
- MetaCyc: SUC-COA
- KNApSAcK: C00019546
- foodb: FDB022375
- chemspider: 83179
- CAS: 604-98-8
- PMhub: MS000016795
- PubChem: 3391
- LipidMAPS: LMFA07050370
- PDB-CCD: SCA
- 3DMET: B04629
- NIKKAJI: J252.493G
- RefMet: Succinyl-CoA
- KNApSAcK: 15380
分类词条
相关代谢途径
Reactome(0)
BioCyc(10)
- aromatic compound degradation
- TCA cycle, aerobic respiration
- phenylacetate degradation
- superpathway of central carbon metabolism
- superpathway of lysine, threonine and methionine biosynthesis I
- methionine biosynthesis I
- acetyl-CoA degradation to acetate
- superpathway of glycolysis, pyruvate dehydrogenase and TCA cycle
- 2-keto glutarate dehydrogenase complex
- lysine biosynthesis I
PlantCyc(0)
代谢反应
885 个相关的代谢反应过程信息。
Reactome(24)
- Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA
- The citric acid (TCA) cycle and respiratory electron transport:
ETF:FAD + FADH2 ⟶ ETF:FADH2 + FAD
- Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA
- The citric acid (TCA) cycle and respiratory electron transport:
ETF:FAD + FADH2 ⟶ ETF:FADH2 + FAD
- Pyruvate metabolism and Citric Acid (TCA) cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Citric acid cycle (TCA cycle):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Ketone body metabolism:
ACA + H+ + NADH ⟶ NAD + bHBA
- Ketone body catabolism:
NAD + bHBA ⟶ ACA + H+ + NADH
- The citric acid (TCA) cycle and respiratory electron transport:
CoQ + ETF:FADH2 ⟶ ETF:FAD + ubiquinol
- Pyruvate metabolism and Citric Acid (TCA) cycle:
CIT ⟶ ISCIT
- Citric acid cycle (TCA cycle):
CIT ⟶ ISCIT
- Fatty acid metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Mitochondrial Fatty Acid Beta-Oxidation:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi
- Propionyl-CoA catabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi
- Metabolism of vitamins and cofactors:
H2O + Oxygen + PXL ⟶ H2O2 + PDXate
- Metabolism of water-soluble vitamins and cofactors:
H2O + Oxygen + PXL ⟶ H2O2 + PDXate
- Cobalamin (Cbl, vitamin B12) transport and metabolism:
Cbl + H+ + Homologues of MMACHC + TPNH ⟶ MMACHC:cob(II)alamin + TPN
- Heme synthesis:
H2O + PBG ⟶ HMBL + ammonia
- Porphyrin metabolism:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN
- Heme biosynthesis:
H2O + PBG ⟶ HMBL + ammonia
BioCyc(21)
- aromatic compound degradation:
NADPH + O2 + phenol ⟶ H2O + NADP+ + catechol
- phenylacetate degradation:
ATP + coenzyme A + phenylacetate ⟶ AMP + phenylacetyl-CoA + pyrophosphate
- TCA cycle, aerobic respiration:
H2O + cis-aconitate ⟶ isocitrate
- 3-oxoadipate degradation:
3-oxoadipate + succinyl-CoA ⟶ 3-oxoadipyl-CoA + succinate
- phenylacetate degradation I (aerobic):
ATP + coenzyme A + phenylacetate ⟶ AMP + H+ + diphosphate + phenylacetyl-CoA
- benzoyl-CoA degradation I (aerobic):
2,3-dihydro-2,3-dihydroxybenzoyl-CoA + H2O + H+ ⟶ 3,4-dehydroadipyl-CoA semialdehyde + formate
- aspartate superpathway:
ATP + ammonia + nicotinate adenine dinucleotide ⟶ AMP + H+ + NAD+ + diphosphate
- superpathway of lysine, threonine and methionine biosynthesis I:
H2O + L-cystathionine ⟶ H+ + L-homocysteine + ammonia + pyruvate
- methionine biosynthesis I:
H2O + L-cystathionine ⟶ H+ + L-homocysteine + ammonia + pyruvate
- pyruvate fermentation to propionate I:
(S)-methylmalonyl-CoA + pyruvate ⟶ oxaloacetate + propanoyl-CoA
- acetyl-CoA degradation to acetate:
ATP + acetate + coenzyme A ⟶ AMP + H+ + acetyl-CoA + diphosphate
- methylmalonyl pathway:
ATP + bicarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate
- tetrapyrrole biosynthesis:
H2O + porphobilinogen ⟶ ammonia + hydroxymethylbilane
- superpathway of central carbon metabolism:
ATP + H2O + pyruvate ⟶ AMP + H+ + phosphate + phosphoenolpyruvate
- TCA cycle:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH
- superpathway of glycolysis, pyruvate dehydrogenase and TCA cycle:
ATP + H2O + pyruvate ⟶ AMP + H+ + phosphate + phosphoenolpyruvate
- superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass:
ATP + H2O + pyruvate ⟶ AMP + H+ + phosphate + phosphoenolpyruvate
- TCA cycle:
2-oxoglutarate + NAD+ + coenzyme A ⟶ CO2 + NADH + succinyl-CoA
- superpathway of glyoxylate bypass and TCA:
2-oxoglutarate + NAD+ + coenzyme A ⟶ CO2 + NADH + succinyl-CoA
- 2-keto glutarate dehydrogenase complex:
α-ketoglutarate + enzyme N6-(lipoyl)lysine ⟶ CO2 + enzyme N6-(S-succinyldihydrolipoyl)lysine
- lysine biosynthesis I:
2-oxoglutarate + N-succinyl-L,L-2,6-diaminopimelate ⟶ N-succinyl-2-amino-6-ketopimelate + glt
WikiPathways(9)
- TCA cycle (Krebs cycle):
citrate ⟶ isocitrate
- Metabolism overview:
NH3 ⟶ Glutamic acid
- TCA cycle (aka Krebs or citric acid cycle):
cis-aconitate ⟶ citrate
- Metabolic reprogramming in pancreatic cancer:
lactate ⟶ pyruvate
- Hemesynthesis defects and porphyrias:
protoporphyrin IX ⟶ Protoheme
- Vitamin B12 disorders:
Homocysteine ⟶ Methionine
- Krebs cycle disorders:
alpha-ketoglutarate ⟶ Succinyl coenzyme A
- TCA cycle:
D-threo-Isocitrate ⟶ 2-oxoglutarate
- Metabolic reprogramming in colon cancer:
KG ⟶ S-CoA
Plant Reactome(612)
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + SACN ⟶ L-Glu + NADH + allysine
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
H2O + L-Asn ⟶ L-Asp + ammonia
- Lysine degradation II:
LIPAM + aKADA ⟶ S-glutaryldihydrolipoamide + carbon dioxide
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
2OG + L-Lys + TPNH ⟶ H2O + SACN + TPN
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate
- Amino acid metabolism:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + SACN ⟶ L-Glu + NADH + allysine
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
2OG + L-Val ⟶ Glu + KIV
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
2OG + L-Lys + TPNH ⟶ H2O + SACN + TPN
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
H2O + L-Asn ⟶ L-Asp + ammonia
- Lysine degradation II:
LIPAM + aKADA ⟶ S-glutaryldihydrolipoamide + carbon dioxide
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
H2O + L-Asn ⟶ L-Asp + ammonia
- Lysine degradation II:
LIPAM + aKADA ⟶ S-glutaryldihydrolipoamide + carbon dioxide
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate
- Amino acid metabolism:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + SACN ⟶ L-Glu + NADH + allysine
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
2OG + L-Lys + TPNH ⟶ H2O + SACN + TPN
- Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate
- Amino acid metabolism:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate
- Amino acid catabolism:
2OG + L-Val ⟶ Glu + KIV
- Lysine degradation II:
H2O + NAD + SACN ⟶ L-Glu + NADH + allysine
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
2OG + L-Lys + TPNH ⟶ H2O + SACN + TPN
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
2OG + L-Lys + TPNH ⟶ H2O + SACN + TPN
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Lysine degradation II:
H2O + NAD + allysine ⟶ NADH + alpha-aminoadipate
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Generation of precursor metabolites and energy:
ISCIT + NAD ⟶ 2OG + H+ + NADH + carbon dioxide
- TCA cycle (plant):
ISCIT + NAD ⟶ 2OG + H+ + NADH + carbon dioxide
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
CIT ⟶ ISCIT
- TCA cycle (plant):
CIT ⟶ ISCIT
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
CIT ⟶ ISCIT
- TCA cycle (plant):
CIT ⟶ ISCIT
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Glutamate synthase cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
ISCIT + NAD ⟶ 2OG + H+ + NADH + carbon dioxide
- TCA cycle (plant):
ISCIT + NAD ⟶ 2OG + H+ + NADH + carbon dioxide
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Glutamate synthase cycle:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
CIT ⟶ ISCIT
- TCA cycle (plant):
CIT ⟶ ISCIT
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Generation of precursor metabolites and energy:
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- TCA cycle (plant):
Ac-CoA + H2O + OAA ⟶ CIT + CoA
- Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
- Glutamate synthase cycle:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi
INOH(10)
- Butanoate metabolism ( Butanoate metabolism ):
Acetoacetic acid + NADH ⟶ (R)-3-Hydroxy-butanoic acid + NAD+
- Succinyl-CoA + Acetoacetic acid = Succinic acid + Acetoacetyl-CoA ( Valine,Leucine and Isoleucine degradation ):
Acetoacetic acid + Succinyl-CoA ⟶ Acetoacetyl-CoA + Succinic acid
- Citrate cycle ( Citrate cycle ):
H2O + cis-Aconitic acid ⟶ Isocitric acid
- CoA + GTP + Succinic acid = Succinyl-CoA + GDP + Orthophosphate ( Citrate cycle ):
GDP + Orthophosphate + Succinyl-CoA ⟶ CoA + GTP + Succinic acid
- CoA + ATP + Succinic acid = Succinyl-CoA + ADP + Orthophosphate ( Citrate cycle ):
ATP + CoA + Succinic acid ⟶ ADP + Orthophosphate + Succinyl-CoA
- Valine,Leucine and Isoleucine degradation ( Valine,Leucine and Isoleucine degradation ):
2-Methyl-3-acetoacetyl-CoA + CoA ⟶ Acetyl-CoA + Propanoyl-CoA
- Glycine and Serine metabolism ( Glycine and Serine metabolism ):
Guanidino-acetic acid + S-Adenosyl-L-methionine ⟶ Creatine + S-Adenosyl-L-homocysteine
- Succinyl-CoA + Dihydro-lipoamide = CoA + S-Succinyl-dihydro-lipoamide ( Citrate cycle ):
CoA + S-Succinyl-dihydro-lipoamide ⟶ Dihydro-lipoamide + Succinyl-CoA
- Propanoate metabolism ( Propanoate metabolism ):
ATP + CoA + Propanoic acid ⟶ AMP + Propanoyl-CoA + Pyrophosphate
- (R)-Methyl-malonyl-CoA = Succinyl-CoA ( Propanoate metabolism ):
Succinyl-CoA ⟶ (R)-Methyl-malonyl-CoA
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(209)
- Citric Acid Cycle:
Citric acid ⟶ Water + cis-Aconitic acid
- Congenital Lactic Acidosis:
Citric acid ⟶ Water + cis-Aconitic acid
- Fumarase Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid
- Mitochondrial Complex II Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid
- 2-Ketoglutarate Dehydrogenase Complex Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid
- Pyruvate Dehydrogenase Deficiency (E3):
Citric acid ⟶ Water + cis-Aconitic acid
- Pyruvate Dehydrogenase Deficiency (E2):
Citric acid ⟶ Water + cis-Aconitic acid
- Warburg Effect:
L-Glutamic acid + NAD + Water ⟶ Ammonia + NADH + Oxoglutaric acid
- The Oncogenic Action of 2-Hydroxyglutarate:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid
- The Oncogenic Action of Succinate:
Citric acid ⟶ Water + cis-Aconitic acid
- The Oncogenic Action of Fumarate:
Citric acid ⟶ Water + cis-Aconitic acid
- Glutaminolysis and Cancer:
L-Glutamine ⟶ Ammonia + L-Glutamic acid
- TCA Cycle:
Citric acid ⟶ Water + cis-Aconitic acid
- The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxyglutaric aciduria:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid
- The Oncogenic Action of D-2-Hydroxyglutarate in Hydroxyglutaric aciduria:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid
- TCA Cycle:
Citric acid ⟶ Water + cis-Aconitic acid
- Citric Acid Cycle:
Citric acid ⟶ Water + cis-Aconitic acid
- Congenital Lactic Acidosis:
Citric acid ⟶ Water + cis-Aconitic acid
- Fumarase Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid
- Mitochondrial Complex II Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid
- 2-Ketoglutarate Dehydrogenase Complex Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid
- Pyruvate Dehydrogenase Deficiency (E3):
Citric acid ⟶ Water + cis-Aconitic acid
- Pyruvate Dehydrogenase Deficiency (E2):
Citric acid ⟶ Water + cis-Aconitic acid
- Warburg Effect:
L-Glutamic acid + NAD + Water ⟶ Ammonia + NADH + Oxoglutaric acid
- Citric Acid Cycle:
Citric acid ⟶ Water + cis-Aconitic acid
- Warburg Effect:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid
- Citric Acid Cycle:
Citric acid ⟶ Water + cis-Aconitic acid
- Warburg Effect:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid
- Citric Acid Cycle:
Citric acid ⟶ Water + cis-Aconitic acid
- Warburg Effect:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid
- Citric Acid Cycle:
Citric acid ⟶ Water + cis-Aconitic acid
- Warburg Effect:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid
- The Oncogenic Action of 2-Hydroxyglutarate:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid
- Glutaminolysis and Cancer:
L-Glutamine ⟶ Ammonia + L-Glutamic acid
- The Oncogenic Action of 2-Hydroxyglutarate:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid
- Glutaminolysis and Cancer:
L-Glutamine ⟶ Ammonia + L-Glutamic acid
- Congenital Lactic Acidosis:
Citric acid ⟶ Water + cis-Aconitic acid
- Fumarase Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid
- Mitochondrial Complex II Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid
- 2-Ketoglutarate Dehydrogenase Complex Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid
- Pyruvate Dehydrogenase Deficiency (E3):
Citric acid ⟶ Water + cis-Aconitic acid
- Pyruvate Dehydrogenase Deficiency (E2):
Citric acid ⟶ Water + cis-Aconitic acid
- Citrate Cycle:
Isocitric acid ⟶ Water + cis-Aconitic acid
- Valine, Leucine, and Isoleucine Degradation:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- Propanoate Metabolism:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Threonine and 2-Oxobutanoate Degradation:
L-Threonine ⟶ 2-Ketobutyric acid + Ammonia
- beta-Ketothiolase Deficiency:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- 2-Methyl-3-hydroxybutyryl-CoA Dehydrogenase Deficiency:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- Propionic Acidemia:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- Maple Syrup Urine Disease:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- 3-Methylglutaconic Aciduria Type I:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- 3-Methylglutaconic Aciduria Type III:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- Methylmalonate Semialdehyde Dehydrogenase Deficiency:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- Methylmalonic Aciduria:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- Isovaleric Aciduria:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- Malonic Aciduria:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Methylmalonic Aciduria Due to Cobalamin-Related Disorders:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- 3-Methylglutaconic Aciduria Type IV:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- Malonyl-CoA Decarboxylase Deficiency:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- 3-Hydroxyisobutyric Acid Dehydrogenase Deficiency:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- 3-Hydroxyisobutyric Aciduria:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- Isobutyryl-CoA Dehydrogenase Deficiency:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- Isovaleric Acidemia:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
- Propanoyl-CoA Degradation:
Adenosine triphosphate + Hydrogen carbonate + Propionyl-CoA ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + S-Methylmalonyl-CoA
- Conversion of Succinate to Propanoate:
Hydrogen Ion + R-Methylmalonyl-CoA ⟶ Carbon dioxide + Propionyl-CoA
- Propanoate Metabolism:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Threonine and 2-Oxobutanoate Degradation:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Valine, Leucine, and Isoleucine Degradation:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- 3-Methylglutaconic Aciduria Type I:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- 3-Methylglutaconic Aciduria Type III:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- 3-Methylglutaconic Aciduria Type IV:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- beta-Ketothiolase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Isovaleric Aciduria:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Malonic Aciduria:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Maple Syrup Urine Disease:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Methylmalonate Semialdehyde Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Methylmalonic Aciduria:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Methylmalonic Aciduria Due to Cobalamin-Related Disorders:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Propionic Acidemia:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Malonyl-CoA Decarboxylase Deficiency:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- 3-Hydroxyisobutyric Acid Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- 3-Hydroxyisobutyric Aciduria:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Isobutyryl-CoA Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Isovaleric Acidemia:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Valine, Leucine, and Isoleucine Degradation:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Propanoate Metabolism:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Threonine and 2-Oxobutanoate Degradation:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Valine, Leucine, and Isoleucine Degradation:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Propanoate Metabolism:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Threonine and 2-Oxobutanoate Degradation:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Propanoate Metabolism:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Threonine and 2-Oxobutanoate Degradation:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Propanoate Metabolism:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Threonine and 2-Oxobutanoate Degradation:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- 3-Methylglutaconic Aciduria Type I:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- 3-Methylglutaconic Aciduria Type III:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- 3-Methylglutaconic Aciduria Type IV:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- beta-Ketothiolase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Isovaleric Aciduria:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Malonic Aciduria:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Maple Syrup Urine Disease:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Methylmalonate Semialdehyde Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Methylmalonic Aciduria:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Methylmalonic Aciduria Due to Cobalamin-Related Disorders:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- Propionic Acidemia:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Malonyl-CoA Decarboxylase Deficiency:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA
- 3-Hydroxyisobutyric Acid Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- 3-Hydroxyisobutyric Aciduria:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Isobutyryl-CoA Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Isovaleric Acidemia:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid
- Lysine Biosynthesis:
Hydrogen Ion + meso-diaminopimelate ⟶ Carbon dioxide + L-Lysine
- Lysine Biosynthesis:
Hydrogen Ion + meso-diaminopimelate ⟶ Carbon dioxide + L-Lysine
- Ketone Body Metabolism:
(R)-3-Hydroxybutyric acid + NAD ⟶ Acetoacetic acid + NADH
- Butyrate Metabolism:
Adenosine triphosphate + Butyric acid + Coenzyme A ⟶ Adenosine monophosphate + Butyryl-CoA + Pyrophosphate
- Succinyl CoA: 3-Ketoacid CoA Transferase Deficiency:
(R)-3-Hydroxybutyric acid + NAD ⟶ Acetoacetic acid + NADH
- TCA Cycle:
Citric acid ⟶ Water + cis-Aconitic acid
- Propanoate Metabolism:
2-iminobutanoate + Hydrogen Ion + Water ⟶ 2-Ketobutyric acid + Ammonium
- TCA cycle (ubiquinol-2):
Citric acid ⟶ Water + cis-Aconitic acid
- TCA cycle (ubiquinol-3):
Citric acid ⟶ Water + cis-Aconitic acid
- TCA cycle (ubiquinol-4):
Citric acid ⟶ Water + cis-Aconitic acid
- TCA cycle (ubiquinol-5):
Citric acid ⟶ Water + cis-Aconitic acid
- TCA cycle (ubiquinol-6):
Citric acid ⟶ Water + cis-Aconitic acid
- TCA cycle (ubiquinol-7):
Citric acid ⟶ Water + cis-Aconitic acid
- TCA cycle (ubiquinol-8):
Citric acid ⟶ Water + cis-Aconitic acid
- TCA cycle (ubiquinol-9):
Citric acid ⟶ Water + cis-Aconitic acid
- TCA cycle (ubiquinol-10):
Citric acid ⟶ Water + cis-Aconitic acid
- TCA cycle (ubiquinol-0):
Citric acid ⟶ Water + cis-Aconitic acid
- Butyrate Metabolism:
Adenosine triphosphate + Butyric acid + Coenzyme A ⟶ Adenosine monophosphate + Butyryl-CoA + Pyrophosphate
- Ketone Body Metabolism:
(R)-3-Hydroxybutyric acid + NAD ⟶ Acetoacetic acid + NADH
- Succinyl CoA: 3-Ketoacid CoA Transferase Deficiency:
(R)-3-Hydroxybutyric acid + NAD ⟶ Acetoacetic acid + NADH
- Butyrate Metabolism:
Adenosine triphosphate + Butyric acid + Coenzyme A ⟶ Adenosine monophosphate + Butyryl-CoA + Pyrophosphate
- Ketone Body Metabolism:
(R)-3-Hydroxybutyric acid + NAD ⟶ Acetoacetic acid + NADH
- Butyrate Metabolism:
Adenosine triphosphate + Butyric acid + Coenzyme A ⟶ Adenosine monophosphate + Butyryl-CoA + Pyrophosphate
- Ketone Body Metabolism:
(R)-3-Hydroxybutyric acid + NAD ⟶ Acetoacetic acid + NADH
- Succinyl CoA: 3-Ketoacid CoA Transferase Deficiency:
(R)-3-Hydroxybutyric acid + NAD ⟶ Acetoacetic acid + NADH
- Ketone Body Metabolism:
Acetoacetic acid + Succinyl-CoA ⟶ Acetoacetyl-CoA + Succinic acid
- TCA Cycle:
Water + cis-Aconitic acid ⟶ D-threo-Isocitric acid
- Propanoate Metabolism:
2-Ketobutyric acid + Coenzyme A ⟶ Formic acid + Propionyl-CoA
- TCA Cycle (Ubiquinol-2):
Water + cis-Aconitic acid ⟶ D-threo-Isocitric acid
- TCA Cycle (Ubiquinol-3):
Water + cis-Aconitic acid ⟶ D-threo-Isocitric acid
- TCA Cycle (Ubiquinol-4):
Water + cis-Aconitic acid ⟶ D-threo-Isocitric acid
- TCA Cycle (Ubiquinol-5):
Water + cis-Aconitic acid ⟶ D-threo-Isocitric acid
- TCA Cycle (Ubiquinol-6):
Water + cis-Aconitic acid ⟶ D-threo-Isocitric acid
- TCA Cycle (Ubiquinol-7):
Water + cis-Aconitic acid ⟶ D-threo-Isocitric acid
- TCA Cycle (Ubiquinol-8):
Water + cis-Aconitic acid ⟶ D-threo-Isocitric acid
- TCA Cycle (Ubiquinol-9):
Water + cis-Aconitic acid ⟶ D-threo-Isocitric acid
- TCA Cycle (Ubiquinol-10):
Water + cis-Aconitic acid ⟶ D-threo-Isocitric acid
- TCA Cycle (Ubiquinol-0):
Water + cis-Aconitic acid ⟶ D-threo-Isocitric acid
- Sphingolipid Metabolism:
L-Serine + Palmityl-CoA ⟶ 3-Dehydrosphinganine + Carbon dioxide
- fatty acid oxidation (Butanoate):
Adenosine triphosphate + Butyric acid + Coenzyme A ⟶ Adenosine triphosphate + Butyryl-CoA
- Phenylethylamine Metabolism:
Adenosine triphosphate + Coenzyme A + Phenylacetic acid ⟶ Adenosine monophosphate + Phenylacetyl-CoA + Pyrophosphate
- Methionine Biosynthesis:
L-Cysteine + O-succinyl-L-homoserine ⟶ Hydrogen Ion + L-Cystathionine + Succinic acid
- Methionine Biosynthesis:
L-Cysteine + O-succinyl-L-homoserine ⟶ Hydrogen Ion + L-Cystathionine + Succinic acid
- Glycolysis and Pyruvate Dehydrogenase:
Adenosine monophosphate + Hydrogen Ion + Phosphate + Phosphoenolpyruvic acid ⟶ Adenosine triphosphate + Pyruvic acid + Water
- Glycine and Serine Metabolism:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Porphyrin Metabolism:
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Acute Intermittent Porphyria:
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Porphyria Variegata (PV):
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Congenital Erythropoietic Porphyria (CEP) or Gunther Disease:
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Dimethylglycine Dehydrogenase Deficiency:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Dihydropyrimidine Dehydrogenase Deficiency (DHPD):
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Sarcosinemia:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Non-Ketotic Hyperglycinemia:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Hereditary Coproporphyria (HCP):
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Dimethylglycine Dehydrogenase Deficiency:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Hyperglycinemia, Non-Ketotic:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- 3-Phosphoglycerate Dehydrogenase Deficiency:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Porphyrin Metabolism:
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Glycine and Serine Metabolism:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Porphyrin Metabolism:
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- 3-Phosphoglycerate Dehydrogenase Deficiency:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Acute Intermittent Porphyria:
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Congenital Erythropoietic Porphyria (CEP) or Gunther Disease:
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Dihydropyrimidine Dehydrogenase Deficiency (DHPD):
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Dimethylglycine Dehydrogenase Deficiency:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Hereditary Coproporphyria (HCP):
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Sarcosinemia:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Non-Ketotic Hyperglycinemia:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Porphyria Variegata (PV):
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Hyperglycinemia, Non-Ketotic:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- 3-Phosphoglycerate Dehydrogenase Deficiency:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Porphyrin Metabolism:
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Glycine and Serine Metabolism:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Porphyrin Metabolism:
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Glycine and Serine Metabolism:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Porphyrin Metabolism:
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Glycine and Serine Metabolism:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Glycine and Serine Metabolism:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Acute Intermittent Porphyria:
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Congenital Erythropoietic Porphyria (CEP) or Gunther Disease:
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Dihydropyrimidine Dehydrogenase Deficiency (DHPD):
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Dimethylglycine Dehydrogenase Deficiency:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Hereditary Coproporphyria (HCP):
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Sarcosinemia:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Non-Ketotic Hyperglycinemia:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Porphyria Variegata (PV):
AH2 + Heme + Oxygen ⟶ A + Biliverdin + Carbon monoxide + Fe2+ + Water
- Hyperglycinemia, Non-Ketotic:
Guanidoacetic acid + S-Adenosylhomocysteine ⟶ Creatine + S-Adenosylmethionine
- Arginine Metabolism:
N-Acetylornithine + Water ⟶ Acetic acid + Ornithine
- 2-Oxoglutarate Decarboxylation to Succinyl-CoA:
Hydrogen Ion + Oxoglutaric acid + a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine ⟶ Carbon dioxide + a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine
- Arginine Metabolism:
N-Acetylornithine + Water ⟶ Acetic acid + Ornithine
- 2-Oxoglutarate Decarboxylation to Succinyl-CoA:
Hydrogen Ion + Oxoglutaric acid + a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine ⟶ Carbon dioxide + a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine
PharmGKB(0)
2 个相关的物种来源信息
- 9606 - Homo sapiens: -
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Lin Tan, Sara A Martinez, Philip L Lorenzi, Anja Karlstaedt. Quantitative Analysis of Acetyl-CoA, Malonyl-CoA, and Succinyl-CoA in Myocytes.
Journal of the American Society for Mass Spectrometry.
2023 Oct; ?(?):. doi:
10.1021/jasms.3c00278
. [PMID: 37812744] - Ioannis Skalidis, Fotis L Kyrilis, Christian Tüting, Farzad Hamdi, Toni K Träger, Jaydeep Belapure, Gerd Hause, Marta Fratini, Francis J O'Reilly, Ingo Heilmann, Juri Rappsilber, Panagiotis L Kastritis. Structural analysis of an endogenous 4-megadalton succinyl-CoA-generating metabolon.
Communications biology.
2023 May; 6(1):552. doi:
10.1038/s42003-023-04885-0
. [PMID: 37217784] - Yuanyuan Hu, John E Cronan. α-proteobacteria synthesize biotin precursor pimeloyl-ACP using BioZ 3-ketoacyl-ACP synthase and lysine catabolism.
Nature communications.
2020 11; 11(1):5598. doi:
10.1038/s41467-020-19251-5
. [PMID: 33154364] - Xiaoxi Meng, Hana Mujahid, Yadong Zhang, Xiaojun Peng, Edilberto D Redoña, Cailin Wang, Zhaohua Peng. Comprehensive Analysis of the Lysine Succinylome and Protein Co-modifications in Developing Rice Seeds.
Molecular & cellular proteomics : MCP.
2019 12; 18(12):2359-2372. doi:
10.1074/mcp.ra119.001426
. [PMID: 31492684] - Yunhe Zhao, Kaidi Cui, Chunmei Xu, Qiuhong Wang, Yao Wang, Zhengqun Zhang, Feng Liu, Wei Mu. Proteomic profile of the Bradysia odoriphaga in response to the microbial secondary metabolite benzothiazole.
Scientific reports.
2016 11; 6(?):37730. doi:
10.1038/srep37730
. [PMID: 27883048] - Bosko M Stojanovski, Gregory A Hunter, Martina Jahn, Dieter Jahn, Gloria C Ferreira. Unstable reaction intermediates and hysteresis during the catalytic cycle of 5-aminolevulinate synthase: implications from using pseudo and alternate substrates and a promiscuous enzyme variant.
The Journal of biological chemistry.
2014 Aug; 289(33):22915-22925. doi:
10.1074/jbc.m114.574731
. [PMID: 24920668] - Sankha S Basu, Eric C Deutsch, Alec A Schmaier, David R Lynch, Ian A Blair. Human platelets as a platform to monitor metabolic biomarkers using stable isotopes and LC-MS.
Bioanalysis.
2013 Dec; 5(24):3009-21. doi:
10.4155/bio.13.269
. [PMID: 24320127] - Teresa A Garrett, Christian R H Raetz, Jennifer D Son, Travis D Richardson, Craig Bartling, Ziqiang Guan. Non-enzymatically derived minor lipids found in Escherichia coli lipid extracts.
Biochimica et biophysica acta.
2011 Nov; 1811(11):827-37. doi:
10.1016/j.bbalip.2011.08.012
. [PMID: 21925285] - Ludek Koreny, Roman Sobotka, Jan Janouskovec, Patrick J Keeling, Miroslav Oborník. Tetrapyrrole synthesis of photosynthetic chromerids is likely homologous to the unusual pathway of apicomplexan parasites.
The Plant cell.
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