Nitrite (BioDeep_00000004379)

 

Secondary id: BioDeep_00001867951

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite


代谢物信息卡片


Nitrosyl hydroxide

化学式: HNO2 (47.0007286)
中文名称: 亚硝酸
谱图信息: 最多检出来源 Macaca mulatta(otcml) 25%

分子结构信息

SMILES: N(=O)O
InChI: InChI=1S/HNO2/c2-1-3/h(H,2,3)

描述信息

Nitrite is a nitrite compound is either a salt or an ester of nitrous acid. Sodium nitrite is used for the curing of meat because it prevents bacterial growth and, in a reaction with the meats myoglobin, gives the product a desirable dark red color. Nitrite can be reduced to nitric oxide or ammonia by many species of bacteria. Under hypoxic conditions, nitrite may release nitric oxide, which causes potent vasodilation. Several mechanisms for nitrite conversion to NO have been described including enzymatic reduction by xanthine oxidoreductase, the mitochondria, and NO synthase (NOS), as well as nonenzymatic acidic disproportionation. -- Wikipedia.
A nitrite compound is either a salt or an ester of nitrous acid. Sodium nitrite is used for the curing of meat because it prevents bacterial growth and, in a reaction with the meats myoglobin, gives the product a desirable dark red color. Nitrite can be reduced to nitric oxide or ammonia by many species of bacteria.

同义名列表

6 个代谢物同义名

Nitrosyl hydroxide; Acid, nitrous; NITROUS ACID; [NO(OH)]; Nitrite; HNO2



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(3)

BioCyc(0)

PlantCyc(1)

代谢反应

142 个相关的代谢反应过程信息。

Reactome(3)

BioCyc(0)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(138)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Siddharth Seshan, Johann Poinapen, Marcel H Zandvoort, Jules B van Lier, Zoran Kapelan. Limitations of a biokinetic model to predict the seasonal variations of nitrous oxide emissions from a full-scale wastewater treatment plant. The Science of the total environment. 2024 Mar; 917(?):170370. doi: 10.1016/j.scitotenv.2024.170370. [PMID: 38280609]
  • Reun-Ping Goh, Xing-Yun Xie, Ya-Chi Lin, Hao-Wen Cheng, Joseph A J Raja, Shyi-Dong Yeh. Rapid selection of potyviral cross-protection effective mutants from the local lesion host after nitrous acid mutagenesis. Molecular plant pathology. 2023 08; 24(8):973-988. doi: 10.1111/mpp.13346. [PMID: 37158451]
  • Yunju Zhang, Meilian Zhao, Yongguo Liu, Yuxi Sun. The influence of a single water molecule on the reaction of BrO + HONO. Journal of molecular graphics & modelling. 2022 11; 116(?):108261. doi: 10.1016/j.jmgm.2022.108261. [PMID: 35926333]
  • Alexandra Maria Kratz, Stefanie Maier, Jens Weber, Minsu Kim, Giacomo Mele, Laura Gargiulo, Anna Lena Leifke, Maria Prass, Raeid M M Abed, Yafang Cheng, Hang Su, Ulrich Pöschl, Bettina Weber. Reactive Nitrogen Hotspots Related to Microscale Heterogeneity in Biological Soil Crusts. Environmental science & technology. 2022 08; 56(16):11865-11877. doi: 10.1021/acs.est.2c02207. [PMID: 35929951]
  • Umeo Takahama, Sachiko Hirota. Further slowing down of hydrolysis of amylose heated with black soybean extract by treating with nitrite under gastric conditions. Scientific reports. 2022 08; 12(1):13212. doi: 10.1038/s41598-022-17476-6. [PMID: 35918428]
  • Aurélie Marion, Julien Morin, Elena Ormeño, Sylvie Dupouyet, Barbara D'Anna, Séverine Boiry, Henri Wortham. Nitrous acid production and uptake by Zea mays plants in growth chambers in the presence of nitrogen dioxide. The Science of the total environment. 2022 Feb; 806(Pt 2):150696. doi: 10.1016/j.scitotenv.2021.150696. [PMID: 34597576]
  • Angelica Guerrero Calderon, Haoran Duan, Kai Yee Seo, Catherine Macintosh, Sergi Astals, Kaili Li, Jingjing Wan, Huijuan Li, Nova Maulani, Zhuan Khai Lim, Zhiguo Yuan, Shihu Hu. The origin of waste activated sludge affects the enhancement of anaerobic digestion by free nitrous acid pre-treatment. The Science of the total environment. 2021 Nov; 795(?):148831. doi: 10.1016/j.scitotenv.2021.148831. [PMID: 34246135]
  • Aurélie Marion, Julien Morin, Adrien Gandolfo, Elena Ormeño, Barbara D'Anna, Henri Wortham. Nitrous acid formation on Zea mays leaves by heterogeneous reaction of nitrogen dioxide in the laboratory. Environmental research. 2021 02; 193(?):110543. doi: 10.1016/j.envres.2020.110543. [PMID: 33253704]
  • Yongchun Liu, Shuangying Ni, Tao Jiang, Shubin Xing, Yusheng Zhang, Xiaolei Bao, Zeming Feng, Xiaolong Fan, Liang Zhang, Haibo Feng. Influence of Chinese New Year overlapping COVID-19 lockdown on HONO sources in Shijiazhuang. The Science of the total environment. 2020 Nov; 745(?):141025. doi: 10.1016/j.scitotenv.2020.141025. [PMID: 32738691]
  • Haoran Duan, Shuhong Gao, Xuan Li, Nur Hafizah Ab Hamid, Guangming Jiang, Min Zheng, Xue Bai, Philip L Bond, Xuanyu Lu, Mariella M Chislett, Shihu Hu, Liu Ye, Zhiguo Yuan. Improving wastewater management using free nitrous acid (FNA). Water research. 2020 Mar; 171(?):115382. doi: 10.1016/j.watres.2019.115382. [PMID: 31855696]
  • Moo Joon Shim, Tae Yoon Jung, Dong Hyck Yoon, Yun Mo Yang, Jannatul Rumky, Yi Yong Yoon. HNO2 treatment of sludge: An alternative way of sludge usage as fertilizer. Journal of environmental management. 2020 Mar; 258(?):110016. doi: 10.1016/j.jenvman.2019.110016. [PMID: 31929058]
  • Magdalena Kowacz, Piotr Warszyński. Beyond esterase-like activity of serum albumin. Histidine-(nitro)phenol radical formation in conversion cascade of p-nitrophenyl acetate and the role of infrared light. Journal of molecular recognition : JMR. 2019 08; 32(8):e2780. doi: 10.1002/jmr.2780. [PMID: 30779238]
  • Maycoll Romero-Güiza, Soraya Zahedi, Victor Monsalvo, Pilar Icaran, Maite Pijuan. Nitrite and free nitrous acid sludge pre-treatments to enhance methane production in continuous anaerobic digestion: Comparing process performance and associated costs. Waste management (New York, N.Y.). 2019 Jul; 95(?):526-534. doi: 10.1016/j.wasman.2019.06.043. [PMID: 31351638]
  • Shu-Hong Gao, Jun Yuan Ho, Lu Fan, Amanda Nouwens, Robert D Hoelzle, Benjamin Schulz, Jianhua Guo, Jizhong Zhou, Zhiguo Yuan, Philip L Bond. A comparative proteomic analysis of Desulfovibrio vulgaris Hildenborough in response to the antimicrobial agent free nitrous acid. The Science of the total environment. 2019 Jul; 672(?):625-633. doi: 10.1016/j.scitotenv.2019.03.442. [PMID: 30974354]
  • Liguo Zhang, Haoran Duan, Liu Ye, Lei Liu, Damien J Batstone, Zhiguo Yuan. Increasing capacity of an anaerobic sludge digester through FNA pre-treatment of thickened waste activated sludge. Water research. 2019 02; 149(?):406-413. doi: 10.1016/j.watres.2018.11.008. [PMID: 30472542]
  • Misa Takahashi, Gen-Ichiro Arimura, Hiromichi Morikawa. Dual nitrogen species involved in foliar uptake of nitrogen dioxide in Arabidopsis thaliana. Plant signaling & behavior. 2019; 14(4):e1582263. doi: 10.1080/15592324.2019.1582263. [PMID: 30810449]
  • Min Zheng, Zhiqiang Zuo, Yizhen Zhang, Yujia Cui, Qian Dong, Yanchen Liu, Xia Huang, Zhiguo Yuan. Nitrite production from urine for sulfide control in sewers. Water research. 2017 10; 122(?):447-454. doi: 10.1016/j.watres.2017.05.048. [PMID: 28624728]
  • Chunxiang Ye, Honglian Gao, Ning Zhang, Xianliang Zhou. Photolysis of Nitric Acid and Nitrate on Natural and Artificial Surfaces. Environmental science & technology. 2016 Apr; 50(7):3530-6. doi: 10.1021/acs.est.5b05032. [PMID: 26936001]
  • Tingting Zhang, Qilin Wang, Liu Ye, Damien Batstone, Zhiguo Yuan. Combined free nitrous acid and hydrogen peroxide pre-treatment of waste activated sludge enhances methane production via organic molecule breakdown. Scientific reports. 2015 Nov; 5(?):16631. doi: 10.1038/srep16631. [PMID: 26565653]
  • Peter J Rix, Andrew Vick, Neil J Attkins, Geoffrey E Barker, Adrian W Bott, Harry Alcorn, Mark T Gladwin, Sruti Shiva, Stephen Bradley, Azra Hussaini, William L Hoye, Ed L Parsley, Hiroko Masamune. Pharmacokinetics, pharmacodynamics, safety, and tolerability of nebulized sodium nitrite (AIR001) following repeat-dose inhalation in healthy subjects. Clinical pharmacokinetics. 2015 Mar; 54(3):261-72. doi: 10.1007/s40262-014-0201-y. [PMID: 25421879]
  • Mauro Tiso, Alan N Schechter. Nitrate reduction to nitrite, nitric oxide and ammonia by gut bacteria under physiological conditions. PloS one. 2015; 10(3):e0119712. doi: 10.1371/journal.pone.0119712. [PMID: 25803049]
  • Filis Morina, Umeo Takahama, Ryo Yamauchi, Sachiko Hirota, Sonja Veljovic-Jovanovic. Quercetin 7-O-glucoside suppresses nitrite-induced formation of dinitrosocatechins and their quinones in catechin/nitrite systems under stomach simulating conditions. Food & function. 2015 Jan; 6(1):219-29. doi: 10.1039/c4fo00695j. [PMID: 25375233]
  • Qilin Wang, Guangming Jiang, Liu Ye, Zhiguo Yuan. Enhancing methane production from waste activated sludge using combined free nitrous acid and heat pre-treatment. Water research. 2014 Oct; 63(?):71-80. doi: 10.1016/j.watres.2014.06.010. [PMID: 24981745]
  • Xue Bai, Forough Ghasemi Naghdi, Liu Ye, Paul Lant, Steven Pratt. Enhanced lipid extraction from algae using free nitrous acid pretreatment. Bioresource technology. 2014 May; 159(?):36-40. doi: 10.1016/j.biortech.2014.01.133. [PMID: 24632439]
  • Vojtech Kouba, Michael Catrysse, Hana Stryjova, Ivana Jonatova, Eveline I P Volcke, Pavel Svehla, Jan Bartacek. The impact of influent total ammonium nitrogen concentration on nitrite-oxidizing bacteria inhibition in moving bed biofilm reactor. Water science and technology : a journal of the International Association on Water Pollution Research. 2014; 69(6):1227-33. doi: 10.2166/wst.2013.757. [PMID: 24647188]
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  • Longyan Zhao, Sensen Lai, Rong Huang, Mingyi Wu, Na Gao, Li Xu, Hongbo Qin, Wenlie Peng, Jinhua Zhao. Structure and anticoagulant activity of fucosylated glycosaminoglycan degraded by deaminative cleavage. Carbohydrate polymers. 2013 Nov; 98(2):1514-23. doi: 10.1016/j.carbpol.2013.07.063. [PMID: 24053834]
  • Jia Zhang, Cheng Yang, Chuanxia Chen, Xiurong Yang. Determination of nitrite and glucose in water and human urine with light-up chromogenic response based on the expeditious oxidation of 3,3',5,5'-tetramethylbenzidine by peroxynitrous acid. The Analyst. 2013 Apr; 138(8):2398-404. doi: 10.1039/c3an00080j. [PMID: 23463362]
  • J Claros, E Jiménez, D Aguado, J Ferrer, A Seco, J Serralta. Effect of pH and HNO2 concentration on the activity of ammonia-oxidizing bacteria in a partial nitritation reactor. Water science and technology : a journal of the International Association on Water Pollution Research. 2013; 67(11):2587-94. doi: 10.2166/wst.2013.132. [PMID: 23752393]
  • M Pijuan, L Ye, Z Yuan. Could nitrite/free nitrous acid favour GAOs over PAOs in enhanced biological phosphorus removal systems?. Water science and technology : a journal of the International Association on Water Pollution Research. 2011; 63(2):345-51. doi: 10.2166/wst.2011.062. [PMID: 21252441]
  • Xiao-Yu Han, Shu-Jun Zhang, Yi-Ping Gan, Hong-Chen Wang, Yong-Zhen Peng. [Start up and maintain of nitritation by the inhibition of FA and FNA]. Huan jing ke xue= Huanjing kexue. 2009 Mar; 30(3):809-14. doi: ". [PMID: 19432333]
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  • Corina Costachel, Bernadette Coddeville, Jean-Paul Latgé, Thierry Fontaine. Glycosylphosphatidylinositol-anchored fungal polysaccharide in Aspergillus fumigatus. The Journal of biological chemistry. 2005 Dec; 280(48):39835-42. doi: 10.1074/jbc.m510163200. [PMID: 16204227]
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