Pterin (BioDeep_00000004141)

 

Secondary id: BioDeep_00000405370

natural product human metabolite PANOMIX_OTCML-2023 Endogenous BioNovoGene_Lab2019


代谢物信息卡片


2-amino-3,4-dihydropteridin-4-one

化学式: C6H5N5O (163.049408)
中文名称: 2-氨基-4-羟基蝶啶
谱图信息: 最多检出来源 Homo sapiens(blood) 0.42%

分子结构信息

SMILES: C1=CN=C2C(=N1)C(=O)N=C(N2)N
InChI: InChI=1S/C6H5N5O/c7-6-10-4-3(5(12)11-6)8-1-2-9-4/h1-2H,(H3,7,9,10,11,12)

描述信息

Pterin is a chemical compound composed of a pyrazine ring and a pyrimidine ring; Pterin is a heterocyclic compound composed of a pyrazine ring and a pyrimidine ring (a pteridine ring system); the pyrimidine ring has a carbonyl oxygen and an amino group. Several tautomers of pterin exist and are shown below. As a group, pterins are compounds that are derivatives of 2-amino-4-oxopteridine, with additional functional groups attached to the pyrazine ring.; the pyrimidine ring has a carbonyl oxygen and an amino group. Several tautomers of pterin exist and are shown below. Pterin belongs to the pteridine family of heterocycles. -- Wikipedia. Pterin is found in soy bean.
Pterin is a chemical compound composed of a pyrazine ring and a pyrimidine ring; the pyrimidine ring has a carbonyl oxygen and an amino group. Several tautomers of pterin exist and are shown below. Pterin belongs to the pteridine family of heterocycles. -- Wikipedia.

同义名列表

20 个代谢物同义名

2-amino-3,4-dihydropteridin-4-one; 2-Amino-quinonoid dihydropterin; 2-Amino-4-hydroxyaminopteridine; 2-Amino-4-hydroxypteridine; 2-Amino-4(1H)-pteridinone; 2-Amino-3H-pteridin-4-one; 2-Amino-4(3H)-pteridinone; 2-Amino-1H-pteridin-4-one; 2-Amino-4-oxopteridine; 4-oxo-2-Aminopteridine; 2-Aminopteridin-4-one; 2-aminopteridin-4-ol; 2-Amino-4-pteridinol; 2-Amino-4-pteridone; Pteridoxamine; 4-Oxopterin; Pterine; Pterin; AHAPT; Pterin



数据库引用编号

28 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Emi Sonemoto, Narumi Kono, Rie Ikeda, Mitsuhiro Wada, Yukitaka Ueki, Kenichiro Nakashima. Practical determination of methotrexate in serum of rheumatic patients by LC-MS/MS. Biomedical chromatography : BMC. 2012 Nov; 26(11):1297-300. doi: 10.1002/bmc.2700. [PMID: 22334305]
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  • Gabriella Allegri, Heleno José Bezerra Costa Netto, Luiz Nelson Lopes Ferreira Gomes, Maria Lúcia Costa de Oliveira, Fernanda Bertão Scalco, Francisco Radler de Aquino Neto. Determination of six pterins in urine by LC-MS/MS. Bioanalysis. 2012 Jul; 4(14):1739-46. doi: 10.4155/bio.12.131. [PMID: 22877220]
  • Svetlana E Nikoulina, Dietmar Fuchs, Phillip Moheno. Effect of orally administered dipterinyl calcium pentahydrate on oral glucose tolerance in diet-induced obese mice. Diabetes, metabolic syndrome and obesity : targets and therapy. 2012; 5(?):43-7. doi: 10.2147/dmso.s29159. [PMID: 22419880]
  • Carolyn Tam, Deborah O'Connor, Gideon Koren. Circulating unmetabolized folic Acid: relationship to folate status and effect of supplementation. Obstetrics and gynecology international. 2012; 2012(?):485179. doi: 10.1155/2012/485179. [PMID: 22529856]
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  • Sanjeewa Gamagedara, Stephen Gibbons, Yinfa Ma. Investigation of urinary pteridine levels as potential biomarkers for noninvasive diagnosis of cancer. Clinica chimica acta; international journal of clinical chemistry. 2011 Jan; 412(1-2):120-8. doi: 10.1016/j.cca.2010.09.015. [PMID: 20869359]
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  • Yoon-Jung Moon, Soo-Jung Kim, Young Mok Park, Young-Ho Chung. Sensing UV/blue: pterin as a UV-A absorbing chromophore of cryptochrome. Plant signaling & behavior. 2010 Sep; 5(9):1127-30. doi: 10.4161/psb.5.9.12567. [PMID: 21150334]
  • Yoon-Jung Moon, Eun-Mi Lee, Young Mok Park, Young Shik Park, Won-Il Chung, Young-Ho Chung. The role of cyanopterin in UV/blue light signal transduction of cyanobacterium Synechocystis sp. PCC 6803 phototaxis. Plant & cell physiology. 2010 Jun; 51(6):969-80. doi: 10.1093/pcp/pcq059. [PMID: 20418333]
  • Phillip Moheno, John Morrey, Dietmar Fuchs. Effect of dipterinyl calcium pentahydrate on hepatitis B virus replication in transgenic mice. Journal of translational medicine. 2010 Mar; 8(?):32. doi: 10.1186/1479-5876-8-32. [PMID: 20356392]
  • Julia Teschner, Nicole Lachmann, Jutta Schulze, Mirco Geisler, Kristina Selbach, Jose Santamaria-Araujo, Janneke Balk, Ralf R Mendel, Florian Bittner. A novel role for Arabidopsis mitochondrial ABC transporter ATM3 in molybdenum cofactor biosynthesis. The Plant cell. 2010 Feb; 22(2):468-80. doi: 10.1105/tpc.109.068478. [PMID: 20164445]
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  • Lada Beara-Lasic, Michael H Pillinger, David S Goldfarb. Advances in the management of gout: critical appraisal of febuxostat in the control of hyperuricemia. International journal of nephrology and renovascular disease. 2010; 3(?):1-10. doi: 10.2147/ijnrd.s5563. [PMID: 21694922]
  • Miriam Smutna, Martin Svoboda, Klara Breinekova. Pterins as sensors of response to the application of Fe3+ -dextran in piglets. Sensors (Basel, Switzerland). 2010; 10(1):890-900. doi: 10.3390/s100100890. [PMID: 22315574]
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  • Florentina Cañada-Cañada, Anunciación Espinosa-Mansilla, Arsenio Muñoz de la Peña, Alicia Mancha de Llanos. Determination of marker pteridins and biopterin reduced forms, tetrahydrobiopterin and dihydrobiopterin, in human urine, using a post-column photoinduced fluorescence liquid chromatographic derivatization method. Analytica chimica acta. 2009 Aug; 648(1):113-22. doi: 10.1016/j.aca.2009.06.045. [PMID: 19616696]
  • Nicola Longo. Disorders of biopterin metabolism. Journal of inherited metabolic disease. 2009 Jun; 32(3):333-42. doi: 10.1007/s10545-009-1067-2. [PMID: 19234759]
  • Rachel A Okrent, Matthew D Brooks, Mary C Wildermuth. Arabidopsis GH3.12 (PBS3) conjugates amino acids to 4-substituted benzoates and is inhibited by salicylate. The Journal of biological chemistry. 2009 Apr; 284(15):9742-54. doi: 10.1074/jbc.m806662200. [PMID: 19189963]
  • Phillip Moheno, Wolfgang Pfleiderer, Dietmar Fuchs. Plasma cytokine concentration changes induced by the antitumor agents dipterinyl calcium pentahydrate (DCP) and related calcium pterins. Immunobiology. 2009; 214(2):135-41. doi: 10.1016/j.imbio.2008.07.003. [PMID: 19167992]
  • Robert Terkeltaub. Gout. Novel therapies for treatment of gout and hyperuricemia. Arthritis research & therapy. 2009; 11(4):236. doi: 10.1186/ar2738. [PMID: 19664185]
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  • Phillip Moheno, Wolfgang Pfleiderer, Antonio G DiPasquale, Arnold L Rheingold, Dietmar Fuchs. Cytokine and IDO metabolite changes effected by calcium pterin during inhibition of MDA-MB-231 xenograph tumors in nude mice. International journal of pharmaceutics. 2008 May; 355(1-2):238-48. doi: 10.1016/j.ijpharm.2007.12.021. [PMID: 18272305]
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  • Gale G Bozzo, Gilles J C Basset, Valeria Naponelli, Alexandre Noiriel, Jesse F Gregory, Andrew D Hanson. Characterization of the folate salvage enzyme p-aminobenzoylglutamate hydrolase in plants. Phytochemistry. 2008 Jan; 69(1):29-37. doi: 10.1016/j.phytochem.2007.06.031. [PMID: 17698154]
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