Nitrofurazone (BioDeep_00000413177)

代谢物信息卡片

Nitrofurazone-13C,15N2

化学式: C6H6N4O4 (198.0389)
中文名称: 呋喃西林-13C,15N2, 呋喃西林, 硝基呋喃酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=C(OC(=C1)[N+](=O)[O-])C=NNC(=O)N
InChI: InChI=1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+

描述信息

P - Antiparasitic products, insecticides and repellents > P01 - Antiprotozoals > P01C - Agents against leishmaniasis and trypanosomiasis > P01CC - Nitrofuran derivatives
B - Blood and blood forming organs > B05 - Blood substitutes and perfusion solutions > B05C - Irrigating solutions > B05CA - Antiinfectives
D - Dermatologicals > D08 - Antiseptics and disinfectants > D08A - Antiseptics and disinfectants > D08AF - Nitrofuran derivatives
D - Dermatologicals > D09 - Medicated dressings > D09A - Medicated dressings > D09AA - Medicated dressings with antiinfectives
S - Sensory organs > S02 - Otologicals > S02A - Antiinfectives > S02AA - Antiinfectives
C78272 - Agent Affecting Nervous System > C29698 - Antispasmodic Agent
S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives
D000890 - Anti-Infective Agents
CONFIDENCE standard compound; INTERNAL_ID 1286; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2678; ORIGINAL_PRECURSOR_SCAN_NO 2674
CONFIDENCE standard compound; INTERNAL_ID 1286; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2695; ORIGINAL_PRECURSOR_SCAN_NO 2692
CONFIDENCE standard compound; INTERNAL_ID 1286; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2685; ORIGINAL_PRECURSOR_SCAN_NO 2682
CONFIDENCE standard compound; INTERNAL_ID 1286; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2680; ORIGINAL_PRECURSOR_SCAN_NO 2676
CONFIDENCE standard compound; INTERNAL_ID 1286; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2704; ORIGINAL_PRECURSOR_SCAN_NO 2701
CONFIDENCE standard compound; INTERNAL_ID 1286; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2698; ORIGINAL_PRECURSOR_SCAN_NO 2695

同义名列表

4 个代谢物同义名

Nitrofurazone-13C,15N2; Nitrofurazone; Nitrofurazone; Nitrofurazone

数据库引用编号

22 个数据库交叉引用编号

ChEBI: CHEBI:44368
KEGG: C08042
KEGGdrug: D00862
PubChem: 5447130
DrugBank: DB00336
ChEMBL: CHEMBL869
MeSH: Nitrofurazone
CAS: 1217220-85-3
CAS: 1958113-24-0
CAS: 112574-44-4
CAS: 59-87-0
MoNA: LU128656
MoNA: LU128655
MoNA: LU128654
MoNA: LU128653
MoNA: LU128652
MoNA: LU128651
PubChem: 10242
PDB-CCD: NFZ
NIKKAJI: J1.921F
RefMet: Nitrofurazone
KNApSAcK: 44368

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表
Cytoplasm	10	BLVRB, CAT, G6PD, GSTA5, GSTP1, HPGDS, MYC, ODC1, PTGS2, XDH
Peripheral membrane protein	3	G6PD, HSD17B6, PTGS2
Endoplasmic reticulum membrane	2	MGST2, PTGS2
Nucleus	5	CTDSPL, FOXL2, GSTP1, MYC, PHF20
cytosol	12	BLVRB, CAT, G6PD, GCLC, GCLM, GSR, GSTA5, GSTP1, HPGDS, ODC1, PHF20, XDH
nucleoplasm	5	BLVRB, FOXL2, HPGDS, MYC, PHF20
Cell membrane	1	JAG1
Early endosome membrane	1	HSD17B6
Multi-pass membrane protein	1	MGST2
Cytoplasm, cytosol	1	G6PD
plasma membrane	3	BLVRB, JAG1, MGST2
Membrane	5	CAT, G6PD, JAG1, MGST2, MYC
apical plasma membrane	1	JAG1
caveola	1	PTGS2
extracellular exosome	7	BLVRB, CAT, CTDSPL, G6PD, GSR, GSTA5, GSTP1
Lumenal side	1	HSD17B6
endoplasmic reticulum	3	HSD17B6, MGST2, PTGS2
extracellular space	3	GNRH1, GSTP1, XDH
adherens junction	1	JAG1
mitochondrion	4	CAT, GCLC, GSR, GSTP1
protein-containing complex	3	CAT, MYC, PTGS2
intracellular membrane-bounded organelle	6	BLVRB, CAT, G6PD, HPGDS, HSD17B6, MGST2
Microsome membrane	3	HSD17B6, MGST2, PTGS2
Single-pass type I membrane protein	1	JAG1
extracellular region	4	CAT, GNRH1, GSTP1, JAG1
cytoplasmic side of plasma membrane	1	G6PD
mitochondrial matrix	2	CAT, GSR
centriolar satellite	1	G6PD
nuclear membrane	1	PHF20
external side of plasma membrane	1	GSR
nucleolus	1	MYC
vesicle	1	GSTP1
focal adhesion	1	CAT
Peroxisome	2	CAT, XDH
sarcoplasmic reticulum	1	XDH
Peroxisome matrix	1	CAT
peroxisomal matrix	1	CAT
peroxisomal membrane	1	CAT
Nucleus inner membrane	1	PTGS2
Nucleus outer membrane	1	PTGS2
nuclear inner membrane	1	PTGS2
nuclear outer membrane	1	PTGS2
neuron projection	1	PTGS2
chromatin	2	FOXL2, MYC
Flemming body	1	FOXL2
Nucleus, nucleolus	1	MYC
nuclear envelope	2	MGST2, MYC
NSL complex	1	PHF20
Nucleus, nucleoplasm	1	MYC
ficolin-1-rich granule lumen	2	CAT, GSTP1
secretory granule lumen	2	CAT, GSTP1
endoplasmic reticulum lumen	1	PTGS2
MLL1 complex	1	PHF20
RNA polymerase II transcription repressor complex	1	MYC
histone acetyltransferase complex	1	PHF20
Rough endoplasmic reticulum	1	MYC
Myc-Max complex	1	MYC
catalase complex	1	CAT
TRAF2-GSTP1 complex	1	GSTP1
glutamate-cysteine ligase complex	2	GCLC, GCLM
nucleoplasmic reticulum	1	MYC

文献列表

Aline de Souza, Cauê Benito Scarim, Paulo Cesar Cotrim, Fernando Barbosa Junior, Bruno Alves Rocha, Leandro Augusto Calixto, Cristiano Jesus Correia, Gabriel Lima de Barros Araújo, Raimar Löbenberg, Nádia Araci Bou-Chacra, Ana Cristina Breithaupt-Faloppa. Hydroxymethylnitrofurazone lymphatic uptake with nanostructured lipid carrier after oral administration in rats. Nanomedicine (London, England). 2024 02; 19(4):293-301. doi: 10.2217/nnm-2023-0263. [PMID: 38270378]
Jeyaraman Anupriya, Ramachandran Rajakumaran, Shen Ming Chen, Raj Karthik, Jeyaraj Vinoth Kumar, Jae-Jin Shim, P Muhammed Shafi, Jeong-Won Lee. Raspberry-like CuWO4 hollow spheres anchored on sulfur-doped g-C3N4 composite: An efficient electrocatalyst for selective electrochemical detection of antibiotic drug nitrofurazone. Chemosphere. 2022 Jun; 296(?):133997. doi: 10.1016/j.chemosphere.2022.133997. [PMID: 35167833]
Ramachandran Rajakumaran, Ramaraj Sukanya, Shen Ming Chen, Raj Karthik, Carmel B Breslin, P Muhammed Shafi. Synthesis and Characterization of Pyrochlore-Type Praseodymium Stannate Nanoparticles: An Effective Electrocatalyst for Detection of Nitrofurazone Drug in Biological Samples. Inorganic chemistry. 2021 Feb; 60(4):2464-2476. doi: 10.1021/acs.inorgchem.0c03377. [PMID: 33534999]
EunChae Ryu, Ji-Sung Park, Sib Sankar Giri, Se Chang Park. A simplified modification to rapidly determine the residues of nitrofurans and their metabolites in aquatic animals by HPLC triple quadrupole mass spectrometry. Environmental science and pollution research international. 2021 Feb; 28(6):7551-7563. doi: 10.1007/s11356-020-11074-7. [PMID: 33037540]
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Fernando Gatti Menezes, Luci Corrêa, Jose Osmar Medina-Pestana, Wilson Ferreira Aguiar, Luis Fernando Aranha Camargo. A randomized clinical trial comparing Nitrofurazone-coated and uncoated urinary catheters in kidney transplant recipients: Results from a pilot study. Transplant infectious disease : an official journal of the Transplantation Society. 2019 Apr; 21(2):e13031. doi: 10.1111/tid.13031. [PMID: 30451342]
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