CHLORDIMEFORM (BioDeep_00000413037)

   


代谢物信息卡片


CHLORDIMEFORM

化学式: C10H13ClN2 (196.0767)
中文名称: 甲醇中杀虫脒溶液
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(C=CC(=C1)Cl)N=CN(C)C
InChI: InChI=1S/C10H13ClN2/c1-8-6-9(11)4-5-10(8)12-7-13(2)3/h4-7H,1-3H3

描述信息

CONFIDENCE standard compound; INTERNAL_ID 751; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5932; ORIGINAL_PRECURSOR_SCAN_NO 5931
D004791 - Enzyme Inhibitors > D008996 - Monoamine Oxidase Inhibitors
D004791 - Enzyme Inhibitors > D014475 - Uncoupling Agents
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals
CONFIDENCE standard compound; INTERNAL_ID 751; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5943; ORIGINAL_PRECURSOR_SCAN_NO 5942
CONFIDENCE standard compound; INTERNAL_ID 751; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5951; ORIGINAL_PRECURSOR_SCAN_NO 5949
CONFIDENCE standard compound; INTERNAL_ID 751; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5951; ORIGINAL_PRECURSOR_SCAN_NO 5949
CONFIDENCE standard compound; INTERNAL_ID 751; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5958; ORIGINAL_PRECURSOR_SCAN_NO 5956
CONFIDENCE standard compound; INTERNAL_ID 751; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5950; ORIGINAL_PRECURSOR_SCAN_NO 5948

同义名列表

3 个代谢物同义名

CHLORDIMEFORM; Chlordimeform; Chlordimeform



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ALB, ATG7, AXIN2, FKBP4, GGPS1, HPGDS, MAPK14, POMC, PTGS2
Peripheral membrane protein 2 ACHE, PTGS2
Endoplasmic reticulum membrane 2 PNPLA6, PTGS2
Nucleus 5 ACHE, ALB, AXIN2, FKBP4, MAPK14
cytosol 10 ALB, ATG7, AXIN2, FKBP4, GGPS1, HPGDS, MAPK14, PNPLA6, PRF1, TNNI3
centrosome 2 ALB, AXIN2
nucleoplasm 4 FKBP4, GGPS1, HPGDS, MAPK14
Cell membrane 5 ACHE, ADRB3, PRF1, PTPRU, TREH
Cell projection, axon 1 FKBP4
Multi-pass membrane protein 3 ADRB3, CACNA1I, PRF1
Synapse 2 ACHE, TAC1
cell junction 1 PTPRU
cell surface 1 ACHE
glutamatergic synapse 1 MAPK14
Golgi apparatus 2 ACHE, ALB
neuromuscular junction 1 ACHE
neuronal cell body 2 FKBP4, TAC1
Cytoplasm, cytosol 1 FKBP4
plasma membrane 7 ACHE, ADRB3, AXIN2, CACNA1I, PRF1, PTPRU, TREH
Membrane 5 ACHE, CACNA1I, PNPLA6, PRF1, TREH
axon 1 TAC1
caveola 1 PTGS2
extracellular exosome 3 ALB, FKBP4, TREH
endoplasmic reticulum 3 ALB, PNPLA6, PTGS2
extracellular space 5 ACHE, ALB, CXCL8, POMC, TAC1
perinuclear region of cytoplasm 3 ACHE, FKBP4, GGPS1
mitochondrion 2 FKBP4, MAPK14
protein-containing complex 3 ALB, FKBP4, PTGS2
intracellular membrane-bounded organelle 1 HPGDS
Microsome membrane 1 PTGS2
Single-pass type I membrane protein 1 PTPRU
Secreted 5 ACHE, ALB, CXCL8, POMC, PRF1
extracellular region 8 ACHE, ALB, ATG7, CXCL8, MAPK14, POMC, PRF1, TAC1
Extracellular side 1 ACHE
anchoring junction 1 ALB
Z disc 1 GGPS1
beta-catenin destruction complex 1 AXIN2
cell-cell junction 1 PTPRU
Cytoplasm, perinuclear region 1 GGPS1
Cytoplasm, cytoskeleton 1 FKBP4
microtubule 1 FKBP4
basement membrane 1 ACHE
secretory granule 1 POMC
axoneme 1 ATG7
nuclear speck 1 MAPK14
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
sarcomere 1 TNNI3
receptor complex 1 ADRB3
neuron projection 1 PTGS2
ciliary basal body 1 ALB
axonal growth cone 1 FKBP4
centriole 1 ALB
spindle pole 2 ALB, MAPK14
blood microparticle 1 ALB
Lipid-anchor, GPI-anchor 2 ACHE, TREH
endosome lumen 1 PRF1
phagophore assembly site 1 ATG7
side of membrane 2 ACHE, TREH
Cytoplasm, myofibril, sarcomere, Z line 1 GGPS1
ficolin-1-rich granule lumen 2 ATG7, MAPK14
secretory granule lumen 3 ATG7, MAPK14, POMC
endoplasmic reticulum lumen 2 ALB, PTGS2
platelet alpha granule lumen 1 ALB
voltage-gated calcium channel complex 1 CACNA1I
Single-pass type III membrane protein 1 PNPLA6
immunological synapse 1 PRF1
synaptic cleft 1 ACHE
Preautophagosomal structure 1 ATG7
cardiac myofibril 1 TNNI3
troponin complex 1 TNNI3
Cytolytic granule 1 PRF1
cytolytic granule lumen 1 PRF1
cardiac Troponin complex 1 TNNI3
[Isoform H]: Cell membrane 1 ACHE
ciliary transition fiber 1 ALB


文献列表

  • Yang-Mei-Qing Hu, Hua-Wei Feng, Shuai Liu, Chang Liu, Peng-Yan Zhao, Man Zhang, Li Zhang, Jian Zhao, Jia-Zeng Li, Xiao-Miao Yu, Hong-Sheng Liu, Jun-Feng Zhu. The preparation of polyclonal antibody against chlordimeform and establishment of detection by indirect competitive ELISA. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2022; 57(2):114-124. doi: 10.1080/03601234.2022.2029274. [PMID: 35049417]
  • Mohamed Ahmed Ibrahim Ahmed, Christoph Franz Adam Vogel. Toxicological Evaluation of Novel Butenolide Pesticide Flupyradifurone Against Culex quinquefasciatus (Diptera: Culicidae) Mosquitoes. Journal of medical entomology. 2020 11; 57(6):1857-1863. doi: 10.1093/jme/tjaa118. [PMID: 32566941]
  • Xue Gao, Yongbin Sun, Haidan You, Yannan Dai, Hao Guo, Qingbiao Zhao. Simultaneous determination of amitraz, chlordimeform, formetanate and metabolites in human blood by liquid chromatography tandem mass spectrometry with phospholipid-removal pretreatment. Biomedical chromatography : BMC. 2019 Apr; 33(4):e4477. doi: 10.1002/bmc.4477. [PMID: 30578570]
  • Xue Gao, Yanglan Tan, Hao Guo. Simultaneous determination of amitraz, chlordimeform, formetanate and their main metabolites in human urine by high performance liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 May; 1052(?):27-33. doi: 10.1016/j.jchromb.2017.03.004. [PMID: 28346886]
  • Mohamed Ahmed Ibrahim Ahmed, Christoph Franz Adam Vogel. The role of octopamine receptor agonists in the synergistic toxicity of certain insect growth regulators (IGRs) in controlling Dengue vector Aedes aegypti (Diptera: Culicidae) mosquito. Acta tropica. 2016 Mar; 155(?):1-5. doi: 10.1016/j.actatropica.2015.11.015. [PMID: 26672383]
  • Mohamed Ahmed Ibrahim Ahmed, Christoph Franz Adam Vogel. Synergistic action of octopamine receptor agonists on the activity of selected novel insecticides for control of dengue vector Aedes aegypti (Diptera: Culicidae) mosquito. Pesticide biochemistry and physiology. 2015 May; 120(?):51-6. doi: 10.1016/j.pestbp.2015.01.014. [PMID: 25987220]
  • Mohamed Ahmed Ibrahim Ahmed, Christoph F A Vogel, Fumio Matsumura. Unique biochemical and molecular biological mechanism of synergistic actions of formamidine compounds on selected pyrethroid and neonicotinoid insecticides on the fourth instar larvae of Aedes aegypti (Diptera: Culicidae). Pesticide biochemistry and physiology. 2015 May; 120(?):57-63. doi: 10.1016/j.pestbp.2015.01.008. [PMID: 25987221]
  • Ren-hui He, Yu-peng Bai. [Effect of scopolamine on the acute severe chlorphenamidine poisoning patients]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. 2012 Apr; 30(4):298-300. doi: . [PMID: 22804943]
  • Ranil Waliwitiya, Peter Belton, Russell A Nicholson, Carl A Lowenberger. Effects of the essential oil constituent thymol and other neuroactive chemicals on flight motor activity and wing beat frequency in the blowfly Phaenicia sericata. Pest management science. 2010 Mar; 66(3):277-89. doi: 10.1002/ps.1871. [PMID: 19890946]
  • Ann Gils, Jean-Marie Stassen, Herbert Nar, Joerg T Kley, Wolfgang Wienen, Uwe J Ries, Paul J Declerck. Characterization and comparative evaluation of a novel PAI-1 inhibitor. Thrombosis and haemostasis. 2002 Jul; 88(1):137-43. doi: 10.1055/s-0037-1613166. [PMID: 12152654]
  • J M Goldman, T E Stoker, S D Perreault, R L Cooper, M A Crider. Influence of the formamidine pesticide chlordimeform on ovulation in the female hamster: dissociable shifts in the luteinizing hormone surge and oocyte release. Toxicology and applied pharmacology. 1993 Aug; 121(2):279-90. doi: 10.1006/taap.1993.1155. [PMID: 8346544]
  • C Jurincic, R Horlbeck, K Metz, K F Klippel. [Acute hemorrhagic cystitis following chlordimeform poisoning ]. Deutsche medizinische Wochenschrift (1946). 1991 May; 116(21):816-8. doi: 10.1055/s-2008-1063684. [PMID: 2032533]
  • J M Goldman, R L Cooper, T L Edwards, G L Rehnberg, W K McElroy, J F Hein. Suppression of the luteinizing hormone surge by chlordimeform in ovariectomized, steroid-primed female rats. Pharmacology & toxicology. 1991 Feb; 68(2):131-6. doi: 10.1111/j.1600-0773.1991.tb02050.x. [PMID: 1852718]
  • T E Stoker, J M Goldman, R L Cooper, W K McElroy. Influence of chlordimeform on alpha-adrenergic receptor-associated mechanisms of hormonal regulation in the rat: pituitary and adrenocortical secretion. Toxicology. 1991; 69(3):257-68. doi: 10.1016/0300-483x(91)90185-4. [PMID: 1658985]
  • J M Goldman, R L Cooper, S C Laws, G L Rehnberg, T L Edwards, W K McElroy, J F Hein. Chlordimeform-induced alterations in endocrine regulation within the male rat reproductive system. Toxicology and applied pharmacology. 1990 Jun; 104(1):25-35. doi: 10.1016/0041-008x(90)90279-4. [PMID: 2113720]
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  • L G Costa, D S Wu, G Olibet, S D Murphy. Formamidine pesticides and alpha 2-adrenoceptors: studies with amitraz and chlordimeform in rats and development of a radioreceptor binding assay. Neurotoxicology and teratology. 1989 Jul; 11(4):405-11. doi: 10.1016/0892-0362(89)90014-7. [PMID: 2552275]
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  • P H Kurtz, G Shaw, A Kelter, R J Jackson. Assessment of potential acute health effects in agricultural workers exposed during the application of chlordimeform. Journal of occupational medicine. : official publication of the Industrial Medical Association. 1987 Jul; 29(7):592-5. doi: NULL. [PMID: 3612336]
  • R Geyer, F Fattal. HPLC determination of the metabolite 4-chloro-o-toluidine in the urine of workers occupationally exposed to chlordimeform. Journal of analytical toxicology. 1987 Jan; 11(1):24-6. doi: 10.1093/jat/11.1.24. [PMID: 3821074]
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  • H Iizuka, T Masuda. Residual fate of chlorphenamidine in rice plant and paddy soil. Bulletin of environmental contamination and toxicology. 1979 Aug; 22(6):745-9. doi: 10.1007/bf02027018. [PMID: 486779]
  • J T Pento, C P Robinson, J A Rieger, F A Horton. The influence of chlordimeform on calcium and glucose homeostasis. Research communications in chemical pathology and pharmacology. 1979 Apr; 24(1):127-42. doi: NULL. [PMID: 432430]
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  • D S Folland, R D Kimbrough, R E Cline, R C Swiggart, W Schaffner. Acute hemorrhagic cystitis. Industrial exposure to the pesticide chlordimeform. JAMA. 1978 Mar; 239(11):1052-5. doi: 10.1001/jama.239.11.1052. [PMID: 628051]
  • C O Knowles, H J Benezet. Mammalian metabolism of chlordimeform. Formation of metabolites containing the urea moiety. Journal of agricultural and food chemistry. 1977 Sep; 25(5):1022-6. doi: 10.1021/jf60213a058. [PMID: 893824]
  • T Arima, H Morooka, T Tanigawa, M Imai, T Tsunashima, S Kita. Methemoglobinemia induced by chlorphenamidine. Acta medica Okayama. 1976 Feb; 30(1):57-60. doi: . [PMID: 135479]
  • H J Benezet, C O Knowles. N'-(4-Chloro-o-tolyl)-N-methylformamidine (demethylchlordimeform) metabolism in the rat. Journal of agricultural and food chemistry. 1976 Jan; 24(1):152-4. doi: 10.1021/jf60203a011. [PMID: 1245660]