Rutamarin (BioDeep_00000406802)

Main id: BioDeep_00000002794

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


2-[6-(2-methylbut-3-en-2-yl)-7-oxo-2,3-dihydrofuro[3,2-g]chromen-2-yl]propan-2-yl acetate

化学式: C21H24O5 (356.1624)
中文名称: 芸香呋喃香豆醇乙酸酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=CC(C)(C)c1cc2cc3c(cc2oc1=O)O[C@H](C(C)(C)OC(C)=O)C3
InChI: InChI=1S/C21H24O5/c1-7-20(3,4)15-9-13-8-14-10-18(21(5,6)26-12(2)22)24-16(14)11-17(13)25-19(15)23/h7-9,11,18H,1,10H2,2-6H3

描述信息

同义名列表

3 个代谢物同义名

2-[6-(2-methylbut-3-en-2-yl)-7-oxo-2,3-dihydrofuro[3,2-g]chromen-2-yl]propan-2-yl acetate; Rutamarin; Rutamarin



数据库引用编号

32 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ANXA5, BCL2, BCL2L1, BIRC5, CASP3, CASP9, XIAP
Peripheral membrane protein 1 ANXA5
Endoplasmic reticulum membrane 2 BCL2, TRPM8
Mitochondrion membrane 2 BCL2L1, MAOA
Nucleus 6 BCL2, BIRC5, CASP3, CASP9, PARP1, XIAP
cytosol 9 ANXA5, BCL2, BCL2L1, BIRC5, CASP3, CASP9, MAOA, PARP1, XIAP
dendrite 2 MAOB, TRPM5
nuclear body 1 PARP1
centrosome 1 BCL2L1
nucleoplasm 4 BIRC5, CASP3, PARP1, XIAP
Cell membrane 5 TNFRSF1A, TRPA1, TRPM5, TRPM8, TRPV1
Cytoplasmic side 3 BCL2L1, MAOA, MAOB
Multi-pass membrane protein 5 TAS2R20, TRPA1, TRPM5, TRPM8, TRPV1
Golgi apparatus membrane 1 TNFRSF1A
cell surface 2 TNFRSF10B, TNFRSF1A
glutamatergic synapse 1 CASP3
Golgi membrane 1 TNFRSF1A
mitochondrial inner membrane 1 BCL2L1
neuronal cell body 4 CASP3, MAOB, TRPM5, TRPV1
sarcolemma 1 ANXA5
Cytoplasm, cytosol 2 BCL2L1, PARP1
plasma membrane 9 BCHE, TAS2R10, TAS2R20, TNFRSF10B, TNFRSF1A, TRPA1, TRPM5, TRPM8, TRPV1
synaptic vesicle membrane 1 BCL2L1
Membrane 12 ANXA5, BCL2, MAOA, PARP1, TAS2R10, TAS2R20, TNFRSF10B, TNFRSF1A, TRPA1, TRPM5, TRPM8, TRPV1
extracellular exosome 1 ANXA5
endoplasmic reticulum 2 BCL2, BCL2L1
extracellular space 2 BCHE, TNFRSF1A
mitochondrion 6 BCL2, BCL2L1, CASP9, MAOA, MAOB, PARP1
protein-containing complex 4 BCL2, BIRC5, CASP9, PARP1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 TNFRSF1A
Secreted 2 BCHE, TNFRSF1A
extracellular region 3 ANXA5, BCHE, TNFRSF1A
Mitochondrion outer membrane 4 BCL2, BCL2L1, MAOA, MAOB
Single-pass membrane protein 3 BCL2, BCL2L1, MAOA
mitochondrial outer membrane 4 BCL2, BCL2L1, MAOA, MAOB
Mitochondrion matrix 1 BCL2L1
mitochondrial matrix 1 BCL2L1
transcription regulator complex 1 PARP1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 BCL2L1
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 BCL2L1
Nucleus membrane 2 BCL2, BCL2L1
Bcl-2 family protein complex 2 BCL2, BCL2L1
nuclear membrane 2 BCL2, BCL2L1
external side of plasma membrane 3 ANXA5, TRPM8, TRPV1
microtubule cytoskeleton 1 BIRC5
nucleolus 1 PARP1
midbody 1 BIRC5
postsynaptic membrane 1 TRPV1
Membrane raft 2 TNFRSF1A, TRPM8
pore complex 1 BCL2
Cytoplasm, cytoskeleton, spindle 1 BIRC5
focal adhesion 1 ANXA5
microtubule 1 BIRC5
spindle 1 BIRC5
GABA-ergic synapse 1 TRPV1
collagen-containing extracellular matrix 1 ANXA5
interphase microtubule organizing center 1 BIRC5
Postsynaptic cell membrane 1 TRPV1
receptor complex 1 TNFRSF1A
Cell projection, neuron projection 1 TRPV1
Zymogen granule membrane 1 ANXA5
chromatin 1 PARP1
stereocilium bundle 1 TRPA1
Chromosome 2 BIRC5, PARP1
centriole 1 BIRC5
Nucleus, nucleolus 1 PARP1
nuclear replication fork 1 PARP1
chromosome, telomeric region 1 PARP1
nuclear chromosome 1 BIRC5
blood microparticle 1 BCHE
site of double-strand break 1 PARP1
nuclear envelope 1 PARP1
Chromosome, centromere 1 BIRC5
Chromosome, centromere, kinetochore 1 BIRC5
monoatomic ion channel complex 1 TRPM5
myelin sheath 1 BCL2
plasma membrane raft 1 TRPM8
endoplasmic reticulum lumen 1 BCHE
kinetochore 1 BIRC5
mitochondrial envelope 1 MAOB
Single-pass type IV membrane protein 2 MAOA, MAOB
nuclear envelope lumen 1 BCHE
apoptosome 1 CASP9
chromosome, centromeric region 1 BIRC5
vesicle membrane 1 ANXA5
chromosome passenger complex 1 BIRC5
cytoplasmic microtubule 1 BIRC5
protein-DNA complex 1 PARP1
spindle microtubule 1 BIRC5
survivin complex 1 BIRC5
death-inducing signaling complex 1 CASP3
site of DNA damage 1 PARP1
Cell projection, dendritic spine membrane 1 TRPV1
dendritic spine membrane 1 TRPV1
endothelial microparticle 1 ANXA5
[Poly [ADP-ribose] polymerase 1, processed N-terminus]: Chromosome 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed C-terminus]: Cytoplasm 1 PARP1
BAD-BCL-2 complex 1 BCL2
tumor necrosis factor receptor superfamily complex 1 TNFRSF1A
caspase complex 1 CASP9
[Isoform Bcl-X(L)]: Mitochondrion inner membrane 1 BCL2L1


文献列表

  • Aldo Fabio Bazaldúa-Rodríguez, Ramiro Quintanilla-Licea, María Julia Verde-Star, Magda Elizabeth Hernández-García, Javier Vargas-Villarreal, Jesús Norberto Garza-González. Furanocoumarins from Ruta chalepensis with Amebicide Activity. Molecules (Basel, Switzerland). 2021 Jun; 26(12):. doi: 10.3390/molecules26123684. [PMID: 34208750]
  • Yongsheng Lin, Qian Wang, Qiong Gu, Hongao Zhang, Cheng Jiang, Jiayuan Hu, Yan Wang, Yuan Yan, Jun Xu. Semisynthesis of (-)-Rutamarin Derivatives and Their Inhibitory Activity on Epstein-Barr Virus Lytic Replication. Journal of natural products. 2017 01; 80(1):53-60. doi: 10.1021/acs.jnatprod.6b00415. [PMID: 28093914]
  • Ulrike Grienke, Judit Mihály-Bison, Daniela Schuster, Taras Afonyushkin, Markus Binder, Shu-hong Guan, Chun-ru Cheng, Gerhard Wolber, Hermann Stuppner, De-an Guo, Valery N Bochkov, Judith M Rollinger. Pharmacophore-based discovery of FXR-agonists. Part II: identification of bioactive triterpenes from Ganoderma lucidum. Bioorganic & medicinal chemistry. 2011 Nov; 19(22):6779-91. doi: 10.1016/j.bmc.2011.09.039. [PMID: 22014750]
  • Judith M Rollinger, Daniela Schuster, Birgit Danzl, Stefan Schwaiger, Patrick Markt, Michaela Schmidtke, Jürg Gertsch, Stefan Raduner, Gerhard Wolber, Thierry Langer, Hermann Stuppner. In silico target fishing for rationalized ligand discovery exemplified on constituents of Ruta graveolens. Planta medica. 2009 Feb; 75(3):195-204. doi: 10.1055/s-0028-1088397. [PMID: 19096995]
  • Aleksandra Orlita, Matylda Sidwa-Gorycka, Jolanta Kumirska, Edmund Maliński, Ewa M Siedlecka, Jerzy Gajdus, Ewa Lojkowska, Piotr Stepnowski. Identification of Ruta graveolens L. metabolites accumulated in the presence of abiotic elicitors. Biotechnology progress. 2008 Jan; 24(1):128-33. doi: 10.1021/bp070261d. [PMID: 18052337]