Taurocholic Acid (BioDeep_00000406031)

Main id: BioDeep_00000002590

 

natural product Bile acids PANOMIX_OTCML-2023 BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


N-(3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oyl)-taurine

化学式: C26H45NO7S (515.291658)
中文名称: 牛磺胆酸, 牛磺胆酸盐, 牛黄胆酸
谱图信息: 最多检出来源 Homo sapiens(natural_products) 11.11%

分子结构信息

SMILES: CC(CCC(=O)NCCS(=O)(=O)O)C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C
InChI: InChI=1S/C26H45NO7S/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34)/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-/m1/s1

描述信息

A bile acid taurine conjugate of cholic acid that usually occurs as the sodium salt of bile in mammals.
D005765 - Gastrointestinal Agents > D002756 - Cholagogues and Choleretics
D005765 - Gastrointestinal Agents > D001647 - Bile Acids and Salts
D005765 - Gastrointestinal Agents > D002793 - Cholic Acids
D013501 - Surface-Active Agents > D003902 - Detergents
MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; WBWWGRHZICKQGZ-HZAMXZRMSA-N_STSL_0093_Taurocholic acid_8000fmol_180416_S2_LC02_MS02_101; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
CONFIDENCE standard compound; INTERNAL_ID 59
Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.
Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.

同义名列表

5 个代谢物同义名

Taurocholic Acid; N-(3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oyl)-taurine; ST 24:1;O5;T; N-Choloyltaurine; Taurocholate



数据库引用编号

49 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

5 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ying Li, Ya-Nan Gao, Ying-Bao Zhu, Wen-Fang Lu, Jia-Yue Yu, Yuan-Yuan Dong, Meng-Yue Xu, Bo Peng, Jun-Zhe Wu, Qing Su, Juan Bai, Xiao-Lian Shi, Yu-Ming Kang, Hong-Bao Li, Meng-Lu Xu. Taurocholic acid ameliorates hypertension through the activation of TGR5 in the hypothalamic paraventricular nucleus. Food & function. 2024 May; 15(9):5088-5102. doi: 10.1039/d4fo00808a. [PMID: 38666497]
  • Ana Clara Sabbione, María Cristina Añón, Adriana Scilingo. Characterization and Bile Acid Binding Capacity of Dietary Fiber Obtained from Three Different Amaranth Products. Plant foods for human nutrition (Dordrecht, Netherlands). 2024 Mar; 79(1):38-47. doi: 10.1007/s11130-023-01116-z. [PMID: 37938455]
  • Zehui Qin, Minhua Li, Juanjuan Cheng, Ziwei Huang, Gaoxiang Ai, Chang Qu, Youliang Xie, Yucui Li, Huijun Liao, Jianhui Xie, Ziren Su. Self-Assembled nanoparticles Combining Berberine and Sodium Taurocholate for Enhanced Anti-Hyperuricemia Effect. International journal of nanomedicine. 2023; 18(?):4101-4120. doi: 10.2147/ijn.s409513. [PMID: 37525694]
  • Zongmei Zheng, Jiao Wei, Xinxin Hou, Fengjing Jia, Zhaozhou Zhang, Haidong Guo, Fuwen Yuan, Feng He, Zunji Ke, Yan Wang, Ling Zhao. A High Hepatic Uptake of Conjugated Bile Acids Promotes Colorectal Cancer-Associated Liver Metastasis. Cells. 2022 Nov; 11(23):. doi: 10.3390/cells11233810. [PMID: 36497071]
  • Tien S Dong, Jonathan P Jacobs, Vatche Agopian, Joseph R Pisegna, Walid Ayoub, Francisco Durazo, Pedram Enayati, Vinay Sundaram, Jihane N Benhammou, Mazen Noureddin, Gina Choi, Venu Lagishetty, Oliver Fiehn, Marc T Goodman, David Elashoff, Shehnaz K Hussain. Duodenal Microbiome and Serum Metabolites Predict Hepatocellular Carcinoma in a Multicenter Cohort of Patients with Cirrhosis. Digestive diseases and sciences. 2022 08; 67(8):3831-3841. doi: 10.1007/s10620-021-07299-2. [PMID: 34799768]
  • Jessica Y Idowu, Bruno Hagenbuch. Free Cholesterol Affects the Function and Localization of Human Na+/Taurocholate Cotransporting Polypeptide (NTCP) and Organic Cation Transporter 1 (OCT1). International journal of molecular sciences. 2022 Jul; 23(15):. doi: 10.3390/ijms23158457. [PMID: 35955590]
  • Dariusz Zakrzewicz, Regina Leidolf, Sebastian Kunz, Simon Franz Müller, Anita Neubauer, Silke Leiting, Nora Goldmann, Felix Lehmann, Dieter Glebe, Joachim Geyer. Tyrosine 146 of the Human Na+/Taurocholate Cotransporting Polypeptide (NTCP) Is Essential for Its Hepatitis B Virus (HBV) Receptor Function and HBV Entry into Hepatocytes. Viruses. 2022 06; 14(6):. doi: 10.3390/v14061259. [PMID: 35746730]
  • Jian Wu, Yanping Xu, Yubao Cui, Mariza Bortolanza, Minjie Wang, Bin Jiang, Meina Yan, Wei Liang, Yiwen Yao, Qiaoling Pan, Jinfeng Yang, Jiong Yu, Dawei Wang, Hongcui Cao, Lanjuan Li. Dynamic changes of serum metabolites associated with infection and severity of patients with acute hepatitis E infection. Journal of medical virology. 2022 06; 94(6):2714-2726. doi: 10.1002/jmv.27669. [PMID: 35199373]
  • Daisuke Watase, Shuichi Setoguchi, Nami Nagata-Akaho, Shotaro Goto, Hirofumi Yamakawa, Ayano Yamada, Mitsuhisa Koga, Yoshiharu Karube, Kazuhisa Matsunaga, Jiro Takata. Cationic N,N-Dimethylglycine Ester Prodrug of 2R-α-Tocotrienol Promotes Intestinal Absorption via Efficient Self-Micellization with Intrinsic Bile Acid Anion. Molecules (Basel, Switzerland). 2022 Apr; 27(9):. doi: 10.3390/molecules27092727. [PMID: 35566078]
  • Jia Xu, Shiwei Xie, Shuyan Chi, Shuang Zhang, Junming Cao, Beiping Tan. Protective effects of taurocholic acid on excessive hepatic lipid accumulation via regulation of bile acid metabolism in grouper. Food & function. 2022 Mar; 13(5):3050-3062. doi: 10.1039/d1fo04085e. [PMID: 35199809]
  • Ana Virseda-Berdices, David Rojo, Isidoro Martínez, Juan Berenguer, Juan González-García, Oscar Brochado-Kith, Amanda Fernández-Rodríguez, Cristina Díez, Víctor Hontañon, Leire Pérez-Latorre, Rafael Micán, Coral Barbas, Salvador Resino, María Angeles Jiménez-Sousa. Metabolomic changes after DAAs therapy are related to the improvement of cirrhosis and inflammation in HIV/HCV-coinfected patients. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Mar; 147(?):112623. doi: 10.1016/j.biopha.2022.112623. [PMID: 35032770]
  • A L Schneider, H Köhler, B Röthlisberger, R Grobholz, V A McLin. Sodium taurocholate co-transporting polypeptide deficiency. Clinics and research in hepatology and gastroenterology. 2022 03; 46(3):101824. doi: 10.1016/j.clinre.2021.101824. [PMID: 34757153]
  • Yun Wang, Yanjing Li, Shaojingya Gao, Xi Yu, Yu Chen, Yunfeng Lin. Tetrahedral Framework Nucleic Acids Can Alleviate Taurocholate-Induced Severe Acute Pancreatitis and Its Subsequent Multiorgan Injury in Mice. Nano letters. 2022 02; 22(4):1759-1768. doi: 10.1021/acs.nanolett.1c05003. [PMID: 35138113]
  • Anne-Margarethe Enge, Florian Kaltner, Christoph Gottschalk, Angelina Kin, Michael Kirstgen, Joachim Geyer, Anja These, Helen Hammer, Oliver Pötz, Albert Braeuning, Stefanie Hessel-Pras. Organic Cation Transporter I and Na+ /taurocholate Co-Transporting Polypeptide are Involved in Retrorsine- and Senecionine-Induced Hepatotoxicity in HepaRG cells. Molecular nutrition & food research. 2022 01; 66(2):e2100800. doi: 10.1002/mnfr.202100800. [PMID: 34826203]
  • L Liu, Y Yang, W Li, Y Li, X Jiang, L Wang. Tanshinone IIA alleviate rifampicin-induced cholestasis by regulating the expression and function of bile salt export pump. Human & experimental toxicology. 2022 Jan; 41(?):9603271221097365. doi: 10.1177/09603271221097365. [PMID: 35544702]
  • Yishuang Tang, Jing Kong, Bingduo Zhou, Xiaosu Wang, Xiaowen Liu, Yi Wang, Shengliang Zhu. Mesenteric Lymph Duct Ligation Alleviates Acute Lung Injury Caused by Severe Acute Pancreatitis Through Inhibition of High Mobility Group Box 1-Induced Inflammation in Rats. Digestive diseases and sciences. 2021 12; 66(12):4344-4353. doi: 10.1007/s10620-020-06801-6. [PMID: 33433807]
  • Liga Skarda, Julia Kowal, Kaspar P Locher. Structure of the Human Cholesterol Transporter ABCG1. Journal of molecular biology. 2021 10; 433(21):167218. doi: 10.1016/j.jmb.2021.167218. [PMID: 34461069]
  • Xuan Qin, Yuanjin Zhang, Jian Lu, Shengbo Huang, Zongjun Liu, Xin Wang. CYP3A deficiency alters bile acid homeostasis and leads to changes in hepatic susceptibility in rats. Toxicology and applied pharmacology. 2021 10; 429(?):115703. doi: 10.1016/j.taap.2021.115703. [PMID: 34461081]
  • Suzhen Lei, Lu Liu, Linyu Ding, Yi Zhang, Hongliang Zeng. Lotus seed resistant starch affects the conversion of sodium taurocholate by regulating the intestinal microbiota. International journal of biological macromolecules. 2021 Sep; 186(?):227-236. doi: 10.1016/j.ijbiomac.2021.07.031. [PMID: 34245735]
  • Yuki Takashima, Kazuki Ishikawa, Rina Miyawaki, Mana Ogawa, Takeshi Ishii, Takumi Misaka, Shoko Kobayashi. Modulatory Effect of Theaflavins on Apical Sodium-Dependent Bile Acid Transporter (ASBT) Activity. Journal of agricultural and food chemistry. 2021 Aug; 69(33):9585-9596. doi: 10.1021/acs.jafc.1c03483. [PMID: 34346218]
  • Anders Ø Petersen, Hanna Julienne, Tuulia Hyötyläinen, Partho Sen, Yong Fan, Helle Krogh Pedersen, Sirkku Jäntti, Tue H Hansen, Trine Nielsen, Torben Jørgensen, Torben Hansen, Pernille Neve Myers, H Bjørn Nielsen, S Dusko Ehrlich, Matej Orešič, Oluf Pedersen. Conjugated C-6 hydroxylated bile acids in serum relate to human metabolic health and gut Clostridia species. Scientific reports. 2021 06; 11(1):13252. doi: 10.1038/s41598-021-91482-y. [PMID: 34168163]
  • Shengchuan Chen, Jingfei Zhu, Li-Qiong Sun, Siying Liu, Tan Zhang, Yuepeng Jin, Chaohao Huang, Dapei Li, Haiping Yao, Jian Huang, Yanghua Qin, Mengtao Zhou, Gang Chen, Qiyu Zhang, Feng Ma. LincRNA-EPS alleviates severe acute pancreatitis by suppressing HMGB1-triggered inflammation in pancreatic macrophages. Immunology. 2021 06; 163(2):201-219. doi: 10.1111/imm.13313. [PMID: 33512718]
  • Hao-Wei Chang, Nathan P McNulty, Matthew C Hibberd, David O'Donnell, Jiye Cheng, Vincent Lombard, Bernard Henrissat, Olga Ilkayeva, Michael J Muehlbauer, Christopher B Newgard, Michael J Barratt, Xi Lin, Jack Odle, Jeffrey I Gordon. Gut microbiome contributions to altered metabolism in a pig model of undernutrition. Proceedings of the National Academy of Sciences of the United States of America. 2021 05; 118(21):. doi: 10.1073/pnas.2024446118. [PMID: 34001614]
  • Qiuju Tian, Ruiyuan Yang, Yan Wang, Jimin Liu, Aileen Wee, Romil Saxena, Lan Wang, Min Li, Liwei Liu, Shan Shan, Yuanyuan Kong, Hong Ma, Xiaojuan Ou, Hong You, Xinyan Zhao, Jidong Jia. A High Serum Level of Taurocholic Acid Is Correlated With the Severity and Resolution of Drug-induced Liver Injury. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2021 05; 19(5):1009-1019.e11. doi: 10.1016/j.cgh.2020.06.067. [PMID: 32634627]
  • Nikolaos N Koliakos, Georgios Renieris, Dimitrios Sotiropoulos, Kalliopi Pavlou, Dionysia-Eirini Droggiti, Theologia Gkavogianni, Anestis Charalampopoulos, Evangelos J Giamarellos-Bourboulis. Immunomodulation Through Beta-D-glucan in Chemically-induced Necrotizing Pancreatitis. The Journal of surgical research. 2021 05; 261(?):74-84. doi: 10.1016/j.jss.2020.12.020. [PMID: 33421796]
  • Toshihide Takagi, Takato Masada, Keiko Minami, Makoto Kataoka, Ken-Ichi Izutsu, Kazuki Matsui, Shinji Yamashita. In Vitro Sensitivity Analysis of the Gastrointestinal Dissolution Profile of Weakly Basic Drugs in the Stomach-to-Intestine Fluid Changing System: Explanation for Variable Plasma Exposure after Oral Administration. Molecular pharmaceutics. 2021 04; 18(4):1711-1719. doi: 10.1021/acs.molpharmaceut.0c01207. [PMID: 33629861]
  • Deliang Ma, Chang Li, Pengling Jiang, Yingjian Jiang, Jiang Wang, Dianliang Zhang. Inhibition of Ferroptosis Attenuates Acute Kidney Injury in Rats with Severe Acute Pancreatitis. Digestive diseases and sciences. 2021 02; 66(2):483-492. doi: 10.1007/s10620-020-06225-2. [PMID: 32219613]
  • Christine Wu, Maria-Elisabeth Smet, Susan Heath, Jennifer Curnow, Ming-Wei Lin, Jacob George, Thushari I Alahakoon. Pregnancy complicated by refractory severe hypercholanaemia from sodium taurocholate co-transporting polypeptide deficiency. The journal of obstetrics and gynaecology research. 2021 Feb; 47(2):822-826. doi: 10.1111/jog.14568. [PMID: 33174277]
  • Zhen Xun, Jinpiao Lin, Qingqing Yu, Can Liu, Jinlan Huang, Hongyan Shang, Jianhui Guo, Yuchen Ye, Wennan Wu, Yongbin Zeng, Songhang Wu, Siyi Xu, Tianbin Chen, Jing Chen, Qishui Ou. Taurocholic acid inhibits the response to interferon-α therapy in patients with HBeAg-positive chronic hepatitis B by impairing CD8+ T and NK cell function. Cellular & molecular immunology. 2021 02; 18(2):461-471. doi: 10.1038/s41423-020-00601-8. [PMID: 33432062]
  • Shuo Wang, Jiang Chen, Hongyu Li, Xingshun Qi, Xu Liu, Xiaozhong Guo. Metabolomic Detection Between Pancreatic Cancer and Liver Metastasis Nude Mouse Models Constructed by Using the PANC1-KAI1/CD82 Cell Line. Technology in cancer research & treatment. 2021 Jan; 20(?):15330338211045204. doi: 10.1177/15330338211045204. [PMID: 34605330]
  • Lauren E Hughes, Clare Ford, Matthew J Brookes, Rousseau Gama. Bile acid diarrhoea: Current and potential methods of diagnosis. Annals of clinical biochemistry. 2021 01; 58(1):22-28. doi: 10.1177/0004563220966139. [PMID: 32998535]
  • Chongyan Zhao, Fang Yang, Feng Lin, Qingsong Qu, Zhixun Li, Xing Liu, Lu Han, Xinyuan Shi. Process optimization in ginseng fermentation by Monascus ruber and study on bile acid-binding ability of fermentation products in vitro. Preparative biochemistry & biotechnology. 2021; 51(2):120-126. doi: 10.1080/10826068.2020.1799389. [PMID: 33342390]
  • Kai Wang, Martin Yan-Chun Chan, Jian Xu, Pik-Shan Li, Xing Liu, Angus Yiu-Fai Lee, Susanna Sau-Tuen Lee, Wing-Tai Cheung. Male-biased fasting-induced changes in hepatic tauro-cholic acid and plasma cholesterol in Sult2a8-haplodeficient mice. Transgenic research. 2020 12; 29(5-6):499-510. doi: 10.1007/s11248-020-00215-w. [PMID: 33029720]
  • Marianne Joseph Naguib, Amira Moustafa Kamel, Ahmed Thabet Negmeldin, Ahmed Hassen Elshafeey, Ibrahim Elsayed. Molecular docking and statistical optimization of taurocholate-stabilized galactose anchored bilosomes for the enhancement of sofosbuvir absorption and hepatic relative targeting efficiency. Drug delivery. 2020 Dec; 27(1):996-1009. doi: 10.1080/10717544.2020.1787557. [PMID: 32611266]
  • Michael Camilleri, Priya Vijayvargiya. The Role of Bile Acids in Chronic Diarrhea. The American journal of gastroenterology. 2020 10; 115(10):1596-1603. doi: 10.14309/ajg.0000000000000696. [PMID: 32558690]
  • Zhifu Xie, Haowen Jiang, Wei Liu, Xinwen Zhang, Dakai Chen, Shuimei Sun, Chendong Zhou, Jia Liu, Sheng Bao, Xiachang Wang, Yinan Zhang, Jia Li, Lihong Hu, Jingya Li. The triterpenoid sapogenin (2α-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling. Cell death & disease. 2020 09; 11(9):770. doi: 10.1038/s41419-020-02974-0. [PMID: 32943612]
  • Iván L Csanaky, Andrew J Lickteig, Youcai Zhang, Curtis D Klaassen. Effects of patent ductus venosus on bile acid homeostasis in aryl hydrocarbon receptor (AhR)-null mice. Toxicology and applied pharmacology. 2020 09; 403(?):115136. doi: 10.1016/j.taap.2020.115136. [PMID: 32679164]
  • Tomokazu Tokoro, Isamu Makino, Shinichi Harada, Koichi Okamoto, Shinichi Nakanuma, Seisho Sakai, Jun Kinoshita, Keishi Nakamura, Tomoharu Miyashita, Hidehiro Tajima, Itasu Ninomiya, Sachio Fushida, Tetsuo Ohta. Interactions Between Neutrophils and Platelets in the Progression of Acute Pancreatitis. Pancreas. 2020 07; 49(6):830-836. doi: 10.1097/mpa.0000000000001585. [PMID: 32541639]
  • Salma Alavi, Jonathan D Mitchell, Jennifer Y Cho, Rui Liu, John C Macbeth, Ansel Hsiao. Interpersonal Gut Microbiome Variation Drives Susceptibility and Resistance to Cholera Infection. Cell. 2020 06; 181(7):1533-1546.e13. doi: 10.1016/j.cell.2020.05.036. [PMID: 32631492]
  • Weiguo Sui, Qing Gan, Fuhua Liu, Minglin Ou, Bingguo Wang, Songbai Liao, Liusheng Lai, Huaizhou Chen, Ming Yang, Yong Dai. Dynamic Metabolomics Study of the Bile Acid Pathway During Perioperative Primary Hepatic Carcinoma Following Liver Transplantation. Annals of transplantation. 2020 Jun; 25(?):e921844. doi: 10.12659/aot.921844. [PMID: 32572018]
  • Monique D Appelman, Marion J D Robin, Esther W M Vogels, Christie Wolzak, Winnie G Vos, Harmjan R Vos, Robert M Van Es, Boudewijn M T Burgering, Stan F J Van de Graaf. The Lipid Raft Component Stomatin Interacts with the Na+ Taurocholate Cotransporting Polypeptide (NTCP) and Modulates Bile Salt Uptake. Cells. 2020 04; 9(4):. doi: 10.3390/cells9040986. [PMID: 32316189]
  • Laura E Russell, Yitian Zhou, Volker M Lauschke, Richard B Kim. In Vitro Functional Characterization and in Silico Prediction of Rare Genetic Variation in the Bile Acid and Drug Transporter, Na+-Taurocholate Cotransporting Polypeptide (NTCP, SLC10A1). Molecular pharmaceutics. 2020 04; 17(4):1170-1181. doi: 10.1021/acs.molpharmaceut.9b01200. [PMID: 32101444]
  • Sarah Farr, Bogdan Stankovic, Simon Hoffman, Hassan Masoudpoor, Chris Baker, Jennifer Taher, Angela E Dean, Sayeepriyadarshini Anakk, Khosrow Adeli. Bile acid treatment and FXR agonism lower postprandial lipemia in mice. American journal of physiology. Gastrointestinal and liver physiology. 2020 04; 318(4):G682-G693. doi: 10.1152/ajpgi.00386.2018. [PMID: 32003602]
  • Cassandra Warden, Joshua M Barnett, Milam A Brantley. Taurocholic acid inhibits features of age-related macular degeneration in vitro. Experimental eye research. 2020 04; 193(?):107974. doi: 10.1016/j.exer.2020.107974. [PMID: 32067977]
  • Chen Luo, Qilin Huang, Xiaohui Yuan, Yi Yang, Bing Wang, Zhu Huang, Lijun Tang, Hongyu Sun. Abdominal paracentesis drainage attenuates severe acute pancreatitis by enhancing cell apoptosis via PI3K/AKT signaling pathway. Apoptosis : an international journal on programmed cell death. 2020 04; 25(3-4):290-303. doi: 10.1007/s10495-020-01597-2. [PMID: 32100210]
  • Lilong Sun, Zhicheng Le, Shuran He, Jingyan Liu, Lixin Liu, Kam W Leong, Hai-Quan Mao, Zhijia Liu, Yongming Chen. Flash Fabrication of Orally Targeted Nanocomplexes for Improved Transport of Salmon Calcitonin across the Intestine. Molecular pharmaceutics. 2020 03; 17(3):757-768. doi: 10.1021/acs.molpharmaceut.9b00827. [PMID: 32011888]
  • Ian B Jeffery, Anubhav Das, Eileen O'Herlihy, Simone Coughlan, Katryna Cisek, Michael Moore, Fintan Bradley, Tom Carty, Meenakshi Pradhan, Chinmay Dwibedi, Fergus Shanahan, Paul W O'Toole. Differences in Fecal Microbiomes and Metabolomes of People With vs Without Irritable Bowel Syndrome and Bile Acid Malabsorption. Gastroenterology. 2020 03; 158(4):1016-1028.e8. doi: 10.1053/j.gastro.2019.11.301. [PMID: 31843589]
  • Ana Ferrero-Andrés, Arnau Panisello-Roselló, Anna Serafín, Joan Roselló-Catafau, Emma Folch-Puy. Polyethylene Glycol 35 (PEG35) Protects against Inflammation in Experimental Acute Necrotizing Pancreatitis and Associated Lung Injury. International journal of molecular sciences. 2020 Jan; 21(3):. doi: 10.3390/ijms21030917. [PMID: 32019239]
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  • Lu Li, Wang-Wei Fu, Rui-Ting Wu, Ye-Hao Song, Wen-Ying Wu, Shu-Hua Yin, Wen-Juan Li, Ming-Yong Xie. Protective effect of Ganoderma atrum polysaccharides in acute lung injury rats and its metabolomics. International journal of biological macromolecules. 2020 Jan; 142(?):693-704. doi: 10.1016/j.ijbiomac.2019.10.010. [PMID: 31739063]
  • Xiaoyu Zhang, Guang Xin, Shiyi Li, Zeliang Wei, Yue Ming, Jiyan Yuan, E Wen, Zhihua Xing, Kui Yu, Youping Li, Junhua Zhang, Boli Zhang, Hai Niu, Wen Huang. Dehydrocholic Acid Ameliorates Sodium Taurocholate-Induced Acute Biliary Pancreatitis in Mice. Biological & pharmaceutical bulletin. 2020; 43(6):985-993. doi: 10.1248/bpb.b20-00021. [PMID: 32475920]
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  • Olivia Pabois, Christian D Lorenz, Richard D Harvey, Isabelle Grillo, Myriam M-L Grundy, Peter J Wilde, Yuri Gerelli, Cécile A Dreiss. Molecular insights into the behaviour of bile salts at interfaces: a key to their role in lipid digestion. Journal of colloid and interface science. 2019 Nov; 556(?):266-277. doi: 10.1016/j.jcis.2019.08.010. [PMID: 31450021]
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