Glucosamine 6-phosphate (BioDeep_00000405427)

   

natural product


代谢物信息卡片


Glucosamine 6-phosphate

化学式: C6H14NO8P (259.0457)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C1C(C(C(C(O1)O)N)O)O)OP(=O)(O)O
InChI: InChI=1S/C6H14NO8P/c7-3-5(9)4(8)2(15-6(3)10)1-14-16(11,12)13/h2-6,8-10H,1,7H2,(H2,11,12,13)/t2-,3-,4-,5-,6+/m1/s1

描述信息

同义名列表

1 个代谢物同义名

Glucosamine 6-phosphate



数据库引用编号

22 个数据库交叉引用编号

分类词条

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 AKT1, G6PD, GLUL, GNPDA1, GPI, MYC, NAGA, OGT, PPP1R8, RBMS3, TNK1
Peripheral membrane protein 3 G6PD, GNPNAT1, TNK1
Endosome membrane 1 GNPNAT1
Mitochondrion membrane 1 OGT
Nucleus 7 AKT1, AMDHD2, GLUL, MYC, OGT, PPP1R8, RBMS3
cytosol 13 AKT1, AMDHD2, G6PD, GFPT1, GLS, GLUL, GNPDA1, GNPNAT1, GPI, NAGK, OGT, PGM3, RBMS3
dendrite 1 NEGR1
mitochondrial membrane 1 OGT
nucleoplasm 4 AKT1, MYC, OGT, PPP1R8
Cell membrane 4 AKT1, GLUL, NEGR1, OGT
Lipid-anchor 1 GLUL
lamellipodium 1 AKT1
Golgi apparatus membrane 1 GBGT1
Synapse 1 GLS
cell cortex 1 AKT1
glutamatergic synapse 2 AKT1, OGT
Golgi apparatus 1 GBGT1
Golgi membrane 3 GBGT1, GNPNAT1, INS
neuronal cell body 1 NEGR1
postsynapse 1 AKT1
Cytoplasm, cytosol 3 G6PD, GLS, GLUL
Lysosome 1 NAGA
plasma membrane 5 AKT1, GLUL, NEGR1, OGT, TNK1
Membrane 7 AKT1, G6PD, GBGT1, GPI, MYC, OGT, TNK1
extracellular exosome 7 G6PD, GFPT1, GLUL, GNPDA1, GPI, NAGA, NAGK
endoplasmic reticulum 1 GLUL
extracellular space 2 GPI, INS
mitochondrion 2 GLS, GLUL
protein-containing complex 3 AKT1, MYC, OGT
intracellular membrane-bounded organelle 1 G6PD
postsynaptic density 1 NEGR1
Secreted 2 GPI, INS
extracellular region 3 GPI, INS, NEGR1
cytoplasmic side of plasma membrane 1 G6PD
mitochondrial matrix 1 GLS
centriolar satellite 1 G6PD
ciliary membrane 1 GPI
microtubule cytoskeleton 1 AKT1
nucleolus 1 MYC
cell-cell junction 1 AKT1
Single-pass type II membrane protein 1 GBGT1
vesicle 2 AKT1, GBGT1
spindle 1 AKT1
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
nuclear speck 1 PPP1R8
ciliary basal body 1 AKT1
chromatin 1 MYC
cell projection 1 OGT
[Isoform 1]: Mitochondrion 1 GLS
[Isoform 2]: Mitochondrion 1 OGT
Nucleus, nucleolus 1 MYC
Lipid-anchor, GPI-anchor 1 NEGR1
spliceosomal complex 1 PPP1R8
nuclear envelope 1 MYC
endosome lumen 1 INS
NSL complex 1 OGT
Nucleus, nucleoplasm 1 MYC
cell body 1 GLUL
side of membrane 1 NEGR1
[Isoform 3]: Cytoplasm 1 OGT
[Isoform 4]: Cytoplasm 1 OGT
Microsome 1 GLUL
ficolin-1-rich granule lumen 1 GPI
secretory granule lumen 2 GPI, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
transport vesicle 1 INS
RNA polymerase II transcription repressor complex 1 MYC
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
ribonucleoprotein complex 1 RBMS3
histone acetyltransferase complex 1 OGT
protein N-acetylglucosaminyltransferase complex 1 OGT
Sin3-type complex 1 OGT
Rough endoplasmic reticulum 1 MYC
[Isoform 3]: Mitochondrion 1 GLS
[Glutaminase kidney isoform, mitochondrial 68 kDa chain]: Mitochondrion matrix 1 GLS
[Glutaminase kidney isoform, mitochondrial 65 kDa chain]: Mitochondrion matrix 1 GLS
glial cell projection 1 GLUL
Myc-Max complex 1 MYC
nucleoplasmic reticulum 1 MYC


文献列表

  • Wongsakorn Suchaoin, Arshad Mahmood, Kesinee Netsomboon, Andreas Bernkop-Schnürch. Zeta-potential-changing nanoparticles conjugated with cell-penetrating peptides for enhanced transfection efficiency. Nanomedicine (London, England). 2017 May; 12(9):963-975. doi: 10.2217/nnm-2016-0345. [PMID: 28440703]
  • Mamoru Nozaki, Munetaka Sugiyama, Jun Duan, Hiroshi Uematsu, Tatsuya Genda, Yasushi Sato. A missense mutation in the glucosamine-6-phosphate N-acetyltransferase-encoding gene causes temperature-dependent growth defects and ectopic lignin deposition in Arabidopsis. The Plant cell. 2012 Aug; 24(8):3366-79. doi: 10.1105/tpc.112.102806. [PMID: 22932674]
  • Chang-Suk Kong, Jung-Ae Kim, Tae Kil Eom, Se-Kwon Kim. Phosphorylated glucosamine inhibits adipogenesis in 3T3-L1 adipocytes. The Journal of nutritional biochemistry. 2010 May; 21(5):438-43. doi: 10.1016/j.jnutbio.2009.01.018. [PMID: 19427183]
  • Juan Wang, Xiang Liu, Yu-He Liang, Lan-Fen Li, Xiao-Dong Su. Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1. FEBS letters. 2008 Sep; 582(20):2973-8. doi: 10.1016/j.febslet.2008.07.040. [PMID: 18675810]
  • Cong Liu, Dan Li, Yu-He Liang, Lan-Fen Li, Xiao-Dong Su. Ring-opening mechanism revealed by crystal structures of NagB and its ES intermediate complex. Journal of molecular biology. 2008 May; 379(1):73-81. doi: 10.1016/j.jmb.2008.03.031. [PMID: 18436239]
  • Davis W Cheng, Yan Jiang, Anath Shalev, Renu Kowluru, Errol D Crook, Lalit P Singh. An analysis of high glucose and glucosamine-induced gene expression and oxidative stress in renal mesangial cells. Archives of physiology and biochemistry. 2006 Oct; 112(4-5):189-218. doi: 10.1080/13813450601093518. [PMID: 17178593]
  • Lalit P Singh, Kenneith Green, Michelle Alexander, Shira Bassly, Errol D Crook. Hexosamines and TGF-beta1 use similar signaling pathways to mediate matrix protein synthesis in mesangial cells. American journal of physiology. Renal physiology. 2004 Feb; 286(2):F409-16. doi: 10.1152/ajprenal.00007.2003. [PMID: 14559714]
  • E D Crook, S T Simmons, M Daniels, L P Singh. Regulation of glutamine:fructose-6-phosphate amidotransferase activity by high glucose and transforming growth factor beta in rat mesangial cells. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 2000 Nov; 48(6):427-34. doi: NULL. [PMID: 11094865]
  • R Lara-Lemus, M L Calcagno. Glucosamine-6-phosphate deaminase from beef kidney is an allosteric system of the V-type. Biochimica et biophysica acta. 1998 Oct; 1388(1):1-9. doi: 10.1016/s0167-4838(98)00141-1. [PMID: 9774701]
  • J K Roberts, N Wade-Jardetzky, O Jardetzky. Intracellular pH measurements by 31P nuclear magnetic resonance. Influence of factors other than pH on 31P chemical shifts. Biochemistry. 1981 Sep; 20(19):5389-94. doi: 10.1021/bi00522a006. [PMID: 7295683]