Cycloleucine (BioDeep_00000400183)
Main id: BioDeep_00000003348
natural product PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C6H11NO2 (129.079)
中文名称: 1-氨基环戊烷甲酸, 环亮氨酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CCC(C1)(C(=O)O)N
InChI: InChI=1S/C6H11NO2/c7-6(5(8)9)3-1-2-4-6/h1-4,7H2,(H,8,9)
描述信息
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant
同义名列表
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:40547
- KEGG: C03969
- PubChem: 2901
- DrugBank: DB04620
- ChEMBL: CHEMBL295830
- MeSH: Cycloleucine
- CAS: 52-52-8
- MoNA: PT100043
- MoNA: PT100040
- PubChem: 6689
- PDB-CCD: AC5
- NIKKAJI: J4.131I
- KNApSAcK: 40547
- LOTUS: LTS0216657
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
5 个相关的物种来源信息
- 2 - Bacteria: LTS0216657
- 1883 - Streptomyces: LTS0216657
- 1873719 - Streptomyces hydrogenans: 10.1007/BF00446556
- 1873719 - Streptomyces hydrogenans: LTS0216657
- 2062 - Streptomycetaceae: LTS0216657
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Tianhang Niu, Jing Zhang, Jing Li, Xiaoping Gao, Hongyan Ma, Yanqiang Gao, Youlin Chang, Jianming Xie. Effects of exogenous glycine betaine and cycloleucine on photosynthetic capacity, amino acid composition, and hormone metabolism in Solanum melongena L.
Scientific reports.
2023 May; 13(1):7626. doi:
10.1038/s41598-023-34509-w
. [PMID: 37165051] - Huifang Kang, Zhiwang Zhang, Lin Yu, Yixing Li, Mingzhen Liang, Lei Zhou. FTO reduces mitochondria and promotes hepatic fat accumulation through RNA demethylation.
Journal of cellular biochemistry.
2018 07; 119(7):5676-5685. doi:
10.1002/jcb.26746
. [PMID: 29384213] - Xinxia Wang, Linna Zhu, Jingqing Chen, Yizhen Wang. mRNA m⁶A methylation downregulates adipogenesis in porcine adipocytes.
Biochemical and biophysical research communications.
2015 Apr; 459(2):201-207. doi:
10.1016/j.bbrc.2015.02.048
. [PMID: 25725156] - Takuma Kato, Makoto Oba, Koyo Nishida, Masakazu Tanaka. Cell-penetrating helical peptides having l-arginines and five-membered ring α,α-disubstituted α-amino acids.
Bioconjugate chemistry.
2014 Oct; 25(10):1761-8. doi:
10.1021/bc5003949
. [PMID: 25188671] - Anne S Henkel, Marc S Elias, Richard M Green. Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis.
The Journal of biological chemistry.
2009 Nov; 284(46):31807-16. doi:
10.1074/jbc.m109.017970
. [PMID: 19762918] - Cristina Setim Freitas, Cristiane Hatsuko Baggio, André Twardowschy, Ana Cristina dos Santos, Bárbara Mayer, Ana Paula Luiz, Cid Aimbiré Moraes dos Santos, Maria Consuelo Andrade Marques, Adair Roberto Soares dos Santos. Involvement of glutamate and cytokine pathways on antinociceptive effect of Pfaffia glomerata in mice.
Journal of ethnopharmacology.
2009 Apr; 122(3):468-72. doi:
10.1016/j.jep.2009.01.033
. [PMID: 19429314] - Suzan Wopereis, Carina M Rubingh, Marjan J van Erk, Elwin R Verheij, Trinette van Vliet, Nicole H P Cnubben, Age K Smilde, Jan van der Greef, Ben van Ommen, Henk F J Hendriks. Metabolic profiling of the response to an oral glucose tolerance test detects subtle metabolic changes.
PloS one.
2009; 4(2):e4525. doi:
10.1371/journal.pone.0004525
. [PMID: 19242536] - Jian Zhuge. A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1.
Molecular and cellular biochemistry.
2008 Jul; 314(1-2):105-12. doi:
10.1007/s11010-008-9770-0
. [PMID: 18414994] - A Kuhl, M G Hahn, M Dumić, J Mittendorf. Alicyclic beta-amino acids in Medicinal Chemistry.
Amino acids.
2005 Aug; 29(2):89-100. doi:
10.1007/s00726-005-0212-y
. [PMID: 15986181] - Ron A Salzman, Jeff A Brady, Scott A Finlayson, Christina D Buchanan, Elizabeth J Summer, Feng Sun, Patricia E Klein, Robert R Klein, Lee H Pratt, Marie-Michèle Cordonnier-Pratt, John E Mullet. Transcriptional profiling of sorghum induced by methyl jasmonate, salicylic acid, and aminocyclopropane carboxylic acid reveals cooperative regulation and novel gene responses.
Plant physiology.
2005 May; 138(1):352-68. doi:
10.1104/pp.104.058206
. [PMID: 15863699] - Ruta Petraitiene, Vidmantas Petraitis, Amy M Kelaher, Alia A Sarafandi, Diana Mickiene, Andreas H Groll, Tin Sein, John Bacher, Thomas J Walsh. Efficacy, plasma pharmacokinetics, and safety of icofungipen, an inhibitor of Candida isoleucyl-tRNA synthetase, in treatment of experimental disseminated candidiasis in persistently neutropenic rabbits.
Antimicrobial agents and chemotherapy.
2005 May; 49(5):2084-92. doi:
10.1128/aac.49.5.2084-2092.2005
. [PMID: 15855534] - Barbra de Vrijer, Timothy R H Regnault, Randall B Wilkening, Giacomo Meschia, Frederick C Battaglia. Placental uptake and transport of ACP, a neutral nonmetabolizable amino acid, in an ovine model of fetal growth restriction.
American journal of physiology. Endocrinology and metabolism.
2004 Dec; 287(6):E1114-24. doi:
10.1152/ajpendo.00259.2004
. [PMID: 15315907] - Vidmantas Petraitis, Ruta Petraitiene, Amy M Kelaher, Alia A Sarafandi, Tin Sein, Diana Mickiene, John Bacher, Andreas H Groll, Thomas J Walsh. Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans.
Antimicrobial agents and chemotherapy.
2004 Oct; 48(10):3959-67. doi:
10.1128/aac.48.10.3959-3967.2004
. [PMID: 15388459] - Micaela Zonta, Annalisa Sebelin, Sara Gobbo, Tommaso Fellin, Tullio Pozzan, Giorgio Carmignoto. Glutamate-mediated cytosolic calcium oscillations regulate a pulsatile prostaglandin release from cultured rat astrocytes.
The Journal of physiology.
2003 Dec; 553(Pt 2):407-14. doi:
10.1113/jphysiol.2003.046706
. [PMID: 14500777] - Tadashi Miyagawa, Takamitsu Oku, Toshio Sasajima, Rovathi Dasai, Bradley Beattie, Ronald Finn, Juri Gelovani Tjuvajev, Ronald Blasberg. Assessment of treatment response by autoradiography with (14)C-aminocyclopentane carboxylic acid, (67)Ga-DTPA, and (18)F-FDG in a herpes simplex virus thymidine kinase/ganciclovir brain tumor model.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2003 Nov; 44(11):1845-54. doi:
. [PMID: 14602869]
- Maciej A Pszczolkowski, Adam Zahand, Sandye M Bushman, John J Brown. Effects of calcium and glutamate receptor agonists on leaf consumption by lepidopteran neonates.
Pharmacology, biochemistry, and behavior.
2003 Jan; 74(2):389-94. doi:
10.1016/s0091-3057(02)01005-5
. [PMID: 12479959] - Barton R Harris, Mark A Prendergast, D Alex Gibson, D Trent Rogers, John A Blanchard, Robert C Holley, May C Fu, Stewart R Hart, Norman W Pedigo, John M Littleton. Acamprosate inhibits the binding and neurotoxic effects of trans-ACPD, suggesting a novel site of action at metabotropic glutamate receptors.
Alcoholism, clinical and experimental research.
2002 Dec; 26(12):1779-93. doi:
10.1097/01.alc.0000042011.99580.98
. [PMID: 12500101] - Remi Tsuchiya, Fumito Yoshiki, Yoshihisa Kudo, Mitsuhiro Morita. Cell type-selective expression of green fluorescent protein and the calcium indicating protein, yellow cameleon, in rat cortical primary cultures.
Brain research.
2002 Nov; 956(2):221-9. doi:
10.1016/s0006-8993(02)03518-7
. [PMID: 12445689] - Rick B Meeker. Metabotropic and NMDA glutamate receptor interactions with osmotic stimuli in supraoptic neurons.
Pharmacology, biochemistry, and behavior.
2002 Sep; 73(2):475-84. doi:
10.1016/s0091-3057(02)00836-5
. [PMID: 12117603] - J Y Lan , V A Skeberdis, T Jover, X Zheng, M V Bennett, R S Zukin. Activation of metabotropic glutamate receptor 1 accelerates NMDA receptor trafficking.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2001 Aug; 21(16):6058-68. doi:
10.1523/jneurosci.21-16-06058.2001
. [PMID: 11487629] - M P Johnson, G Kelly, M Chamberlain. Changes in rat serum corticosterone after treatment with metabotropic glutamate receptor agonists or antagonists.
Journal of neuroendocrinology.
2001 Aug; 13(8):670-7. doi:
10.1046/j.1365-2826.2001.00678.x
. [PMID: 11489083] - F Yuan, T Wang, L Luo, Y Sun, L Zhang, B Qu. Development of cytotoxic cerebral edema in rats following intracaudatum injection of tACPD, an agonist of metabotropic glutamate receptors.
Chinese medical journal.
2000 Aug; 113(8):728-32. doi:
NULL
. [PMID: 11776058] - J F Perrier, J Noraberg, M Simon, J Hounsgaard. Dedifferentiation of intrinsic response properties of motoneurons in organotypic cultures of the spinal cord of the adult turtle.
The European journal of neuroscience.
2000 Jul; 12(7):2397-404. doi:
10.1046/j.1460-9568.2000.00134.x
. [PMID: 10947818] - A Copani, C Romano, V Di Giorgi Gerevini, A Nicosia, G Casabona, M Storto, V Mutel, F Nicoletti. Reducing conditions differentially affect the functional and structural properties of group-I and -II metabotropic glutamate receptors.
Brain research.
2000 Jun; 867(1-2):165-72. doi:
10.1016/s0006-8993(00)02293-9
. [PMID: 10837810] - T L Pannabecker, K Völker, S Silbernagl, W H Dantzler. Cycloleucine fluxes during rat vasa recta and loop microinfusions in vivo and loop microperfusions in vitro.
Pflugers Archiv : European journal of physiology.
2000 Mar; 439(5):517-23. doi:
10.1007/s004249900219
. [PMID: 10764209] - R Bianchi, F Calzi, S Savaresi, R Sciarretta-Birolo, R Bellasio, V Tsankova, M T Tacconi. Biochemical analysis of myelin lipids and proteins in a model of methyl donor pathway deficit: effect of S-adenosylmethionine.
Experimental neurology.
1999 Sep; 159(1):258-66. doi:
10.1006/exnr.1999.7132
. [PMID: 10486194] - W M Al-Ghoul, R B Meeker, R S Greenwood. Kindled seizures increase metabotropic glutamate receptor expression and function in the rat supraoptic nucleus.
Journal of neuroscience research.
1998 Nov; 54(3):412-23. doi:
10.1002/(sici)1097-4547(19981101)54:3<412::aid-jnr12>3.0.co;2-e
. [PMID: 9819146] - J Becker, Z Li, C R Noe. Molecular and pharmacological characterization of recombinant rat/mice N-methyl-D-aspartate receptor subtypes in the yeast Saccharomyces cerevisiae.
European journal of biochemistry.
1998 Sep; 256(2):427-35. doi:
10.1046/j.1432-1327.1998.2560427.x
. [PMID: 9760184] - R Balázs, S Miller, Y Chun, J O'Toole, C W Cotman. Metabotropic glutamate receptor agonists potentiate cyclic AMP formation induced by forskolin or beta-adrenergic receptor activation in cerebral cortical astrocytes in culture.
Journal of neurochemistry.
1998 Jun; 70(6):2446-58. doi:
10.1046/j.1471-4159.1998.70062446.x
. [PMID: 9603209] - A P Kozikowski, D Steensma, G L Araldi, W Tückmantel, S Wang, S Pshenichkin, E Surina, J T Wroblewski. Synthesis and biology of the conformationally restricted ACPD analogue, 2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid-I, a potent mGluR agonist.
Journal of medicinal chemistry.
1998 May; 41(10):1641-50. doi:
10.1021/jm970719q
. [PMID: 9572889] - L M Console-Bram, D H Baird, S G Fitzpatrick-McElligott, J G McElligott. Modulation of GAP-43 mRNA by GABA and glutamate in cultured cerebellar granule cells.
Brain research.
1998 Feb; 783(2):316-25. doi:
10.1016/s0006-8993(97)01386-3
. [PMID: 9507175] - R Saunders, S R Nahorski, R A Challiss. A modulatory effect of extracellular Ca2+ on type 1alpha metabotropic glutamate receptor-mediated signalling.
Neuropharmacology.
1998; 37(2):273-6. doi:
10.1016/s0028-3908(98)00027-6
. [PMID: 9680253] - M R Young, S M Fleetwood-Walker, T Dickinson, G Blackburn-Munro, H Sparrow, P J Birch, C Bountra. Behavioural and electrophysiological evidence supporting a role for group I metabotropic glutamate receptors in the mediation of nociceptive inputs to the rat spinal cord.
Brain research.
1997 Nov; 777(1-2):161-9. doi:
. [PMID: 9449425]
- B Wroblewska, J T Wroblewski, S Pshenichkin, A Surin, S E Sullivan, J H Neale. N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells.
Journal of neurochemistry.
1997 Jul; 69(1):174-81. doi:
10.1046/j.1471-4159.1997.69010174.x
. [PMID: 9202308] - P J Flor, J Gomeza, M A Tones, R Kuhn, J P Pin, T Knöpfel. The C-terminal domain of the mGluR1 metabotropic glutamate receptor affects sensitivity to agonists.
Journal of neurochemistry.
1996 Jul; 67(1):58-63. doi:
10.1046/j.1471-4159.1996.67010058.x
. [PMID: 8667026] - C Thomsen, V Bruno, F Nicoletti, M Marinozzi, R Pellicciari. (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine, a potent and selective antagonist of type 2 metabotropic glutamate receptors.
Molecular pharmacology.
1996 Jul; 50(1):6-9. doi:
NULL
. [PMID: 8700119] - A Pintor, S Fortuna, P Lorenzini, A Pascale, F Battaini, C Avellino, L Malvezzi Campeggi, S Salvati. Influences of hypothyroidism on lipid composition and inositol lipid-linked receptors responsiveness and protein kinase C (PKC) activity in the cerebral cortex of Lewis rats.
Neurochemical research.
1996 May; 21(5):541-5. doi:
10.1007/bf02527750
. [PMID: 8726960] - G Lombardi, P Leonardi, F Moroni. Metabotropic glutamate receptors, transmitter output and fatty acids: studies in rat brain slices.
British journal of pharmacology.
1996 Jan; 117(1):189-95. doi:
10.1111/j.1476-5381.1996.tb15173.x
. [PMID: 8825362] - M Tanimoto, K Roberts, L Dolan. Ethylene is a positive regulator of root hair development in Arabidopsis thaliana.
The Plant journal : for cell and molecular biology.
1995 Dec; 8(6):943-8. doi:
10.1046/j.1365-313x.1995.8060943.x
. [PMID: 8580964] - R K Lee, R J Wurtman, A J Cox, R M Nitsch. Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors.
Proceedings of the National Academy of Sciences of the United States of America.
1995 Aug; 92(17):8083-7. doi:
10.1073/pnas.92.17.8083
. [PMID: 7644542] - M R Young, S M Fleetwood-Walker, R Mitchell, T Dickinson. The involvement of metabotropic glutamate receptors and their intracellular signalling pathways in sustained nociceptive transmission in rat dorsal horn neurons.
Neuropharmacology.
1995 Aug; 34(8):1033-41. doi:
10.1016/0028-3908(95)00071-d
. [PMID: 8532152] - M Zanol, R Hermann, A Bernareggi, M Borgonovi, E Taglietti, L F Zerilli. HPLC method for the quantitation of cispentacin enantiomers in rat urine.
Bollettino chimico farmaceutico.
1995 Jul; 134(7):390-3. doi:
NULL
. [PMID: 7546543] - C Joly, J Gomeza, I Brabet, K Curry, J Bockaert, J P Pin. Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
1995 May; 15(5 Pt 2):3970-81. doi:
10.1523/jneurosci.15-05-03970.1995
. [PMID: 7751958] - C H Lang, M Ajmal. Metabolic, hormonal, and hemodynamic changes induced by metabotropic excitatory amino acid agonist (1S,3R)-ACPD.
The American journal of physiology.
1995 Apr; 268(4 Pt 2):R1026-33. doi:
10.1152/ajpregu.1995.268.4.r1026
. [PMID: 7733385] - A Copani, V M Bruno, V Barresi, G Battaglia, D F Condorelli, F Nicoletti. Activation of metabotropic glutamate receptors prevents neuronal apoptosis in culture.
Journal of neurochemistry.
1995 Jan; 64(1):101-8. doi:
10.1046/j.1471-4159.1995.64010101.x
. [PMID: 7798903] - C Thomsen, A Bau, P Faarup, C Foged, A Kanstrup, P D Suzdak. Effects of bromohomoibotenate on metabotropic glutamate receptors.
Neuroreport.
1994 Dec; 5(18):2417-20. doi:
10.1097/00001756-199412000-00003
. [PMID: 7696571] - C Thomsen, L Hansen, P D Suzdak. L-glutamate uptake inhibitors may stimulate phosphoinositide hydrolysis in baby hamster kidney cells expressing mGluR1a via heteroexchange with L-glutamate without direct activation of mGluR1a.
Journal of neurochemistry.
1994 Dec; 63(6):2038-47. doi:
10.1046/j.1471-4159.1994.63062038.x
. [PMID: 7964721] - P M Bungay, J D Fenstermacher, P Krindel, R L Dedrick, C S Patlak. Cross-flow membrane plasmapheresis technique for continuous ex vivo plasma sampling.
Journal of pharmacological and toxicological methods.
1994 Nov; 32(3):177-85. doi:
10.1016/1056-8719(94)90072-8
. [PMID: 7858312] - N Gabellini, R M Manev, H Manev. Is the heterologous expression of metabotropic glutamate receptors (mGluRs) an appropriate method to study the mGluR function? Experience with human embryonic kidney 293 cells transfected with mGluR1.
Neurochemistry international.
1994 Jun; 24(6):533-9. doi:
10.1016/0197-0186(94)90004-3
. [PMID: 7981634] - G Lombardi, G Mannaioni, P Leonardi, G Cherici, V Carlà, F Moroni. Ammonium acetate inhibits ionotropic receptors and differentially affects metabotropic receptors for glutamate.
Journal of neural transmission. General section.
1994; 97(3):187-96. doi:
10.1007/bf02336140
. [PMID: 7532952] - S Miller, R J Bridges, C W Cotman. Stimulation of phosphoinositide hydrolysis by trans-(+/-)-ACPD is greatly enhanced when astrocytes are cultured in a serum-free defined medium.
Brain research.
1993 Jul; 618(1):175-8. doi:
10.1016/0006-8993(93)90443-q
. [PMID: 8402173] - M Favaron, R M Manev, P Candeo, R Arban, N Gabellini, A P Kozikowski, H Manev. Trans-azetidine-2,4-dicarboxylic acid activates neuronal metabotropic receptors.
Neuroreport.
1993 Jul; 4(7):967-70. doi:
10.1097/00001756-199307000-00033
. [PMID: 8369491] - R M Manev, N Gabellini, H Manev. Polyamines modulate the function of transfected glutamate receptor mGluR1a.
Neuroreport.
1993 Jun; 4(6):830-2. doi:
10.1097/00001756-199306000-00059
. [PMID: 8394160] - R M Manev, M Favaron, N Gabellini, P Candeo, H Manev. Functional evidence for a L-AP3-sensitive metabotropic receptor different from glutamate metabotropic receptor mGluR1.
Neuroscience letters.
1993 May; 155(1):73-6. doi:
10.1016/0304-3940(93)90676-c
. [PMID: 8361667] - R Muñíz, L Burguillo, J R del Castillo. Effect of starvation on neutral amino acid transport in isolated small-intestinal cells from guinea pigs.
Pflugers Archiv : European journal of physiology.
1993 Apr; 423(1-2):59-66. doi:
10.1007/bf00374961
. [PMID: 8488093] - E C Foulkes, S Blanck. Volume of renal cortical cytoplasm in rabbits, and basolateral transport gradients of cycloleucine and p-aminohippurate.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1993 Mar; 202(3):302-6. doi:
10.3181/00379727-202-43539
. [PMID: 8437985] - H C Winter, T Ueda. Glutamate uptake system in the presynaptic vesicle: glutamic acid analogs as inhibitors and alternate substrates.
Neurochemical research.
1993 Jan; 18(1):79-85. doi:
10.1007/bf00966925
. [PMID: 8096630] - Y W Tang, Y M Yu, J F Burke. Uptake of alpha-aminoisobutyric acid and cycloleucine on skeletal muscles in burned rats.
Burns : journal of the International Society for Burn Injuries.
1992 Feb; 18(1):9-14. doi:
10.1016/0305-4179(92)90111-7
. [PMID: 1558687] - E C Foulkes, S Blanck. Cadmium inhibition of basolateral solute fluxes in rabbit renal tubules and the nature of cycloleucine uptake.
Toxicology and applied pharmacology.
1991 Mar; 108(1):150-6. doi:
10.1016/0041-008x(91)90278-m
. [PMID: 2006502] - M J Courtney, J J Lambert, D G Nicholls. The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium in cultured cerebellar granule cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
1990 Dec; 10(12):3873-9. doi:
10.1523/jneurosci.10-12-03873.1990
. [PMID: 1980131] - M Lakshmanan, E Goncalves, G Lessly, D Foti, J Robbins. The transport of thyroxine into mouse neuroblastoma cells, NB41A3: the effect of L-system amino acids.
Endocrinology.
1990 Jun; 126(6):3245-50. doi:
10.1210/endo-126-6-3245
. [PMID: 2351115] - E C Foulkes, S Blanck. Site of uptake of nonfiltered amino acid in the rabbit kidney.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1990 Jan; 193(1):56-9. doi:
10.3181/00379727-193-42990
. [PMID: 2294522] - T Fujiwara, T Matsuzawa, H Kawai, R Kawashima, M Itoh, S Watanuki, T Takahashi, R Iwata, T Ido. Kinetic evaluation of 11C-1-aminocyclopentane carboxylic acid in rabbits bearing VX-2 tumors using positron emission tomography.
Japanese journal of cancer research : Gann.
1989 Dec; 80(12):1257-60. doi:
10.1111/j.1349-7006.1989.tb01663.x
. [PMID: 2516853] - E C Foulkes. Role of basolateral cell membranes in organic solute reabsorption in rabbit kidneys.
The American journal of physiology.
1987 Jun; 252(6 Pt 2):F1042-7. doi:
10.1152/ajprenal.1987.252.6.f1042
. [PMID: 3591952] - B J Maroni, G Karapanos, W E Mitch. System ASC and sodium-independent neutral amino acid transport in muscle of uremic rats.
The American journal of physiology.
1986 Jul; 251(1 Pt 2):F81-6. doi:
10.1152/ajprenal.1986.251.1.f81
. [PMID: 3524267] - C Cheeks, R P Wedeen. Renal tubular transport of delta-aminolevulinic acid in rat.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1986 Apr; 181(4):596-601. doi:
10.3181/00379727-181-42297
. [PMID: 3081910] - H Davson, D J Begley, D G Chain, F O Briggs, M T Shepherd. Steady-state distribution of cycloleucine and alpha-aminoisobutyric acid between plasma and cerebrospinal fluid.
Experimental neurology.
1986 Jan; 91(1):163-73. doi:
10.1016/0014-4886(86)90034-8
. [PMID: 3940873] - D L Prince, R M Kotin, D T Dubin. Evidence that the methylation inhibitor cycloleucine causes accumulation of a discrete ribosomal RNA precursor in hamster mitochondria.
Molecular biology reports.
1986; 11(1):51-5. doi:
10.1007/bf00417596
. [PMID: 3633018] - E C Foulkes. Tubular reabsorption delay of amino acids in the rabbit kidney.
The American journal of physiology.
1985 Dec; 249(6 Pt 2):F878-83. doi:
10.1152/ajprenal.1985.249.6.f878
. [PMID: 4073270] - A C Kroes, J Lindemans, J Abels. Synergistic growth inhibiting effect of nitrous oxide and cycloleucine in experimental rat leukaemia.
British journal of cancer.
1984 Dec; 50(6):793-800. doi:
10.1038/bjc.1984.258
. [PMID: 6498076] - E C Foulkes, S Blanck. The selective action of nickel on tubule function in rabbit kidneys.
Toxicology.
1984 Dec; 33(3-4):245-9. doi:
10.1016/0300-483x(84)90041-6
. [PMID: 6515659] - J A Schafer, M L Watkins. Transport of L-cystine in isolated perfused proximal straight tubules.
Pflugers Archiv : European journal of physiology.
1984 Jun; 401(2):143-51. doi:
10.1007/bf00583874
. [PMID: 6433321] - M Stern, W A Walker. Food proteins and gut mucosal barrier I. Binding and uptake of cow's milk proteins by adult rat jejunum in vitro.
The American journal of physiology.
1984 May; 246(5 Pt 1):G556-62. doi:
10.1152/ajpgi.1984.246.5.g556
. [PMID: 6720953] - B Elsenhans, D Zenker, W F Caspary. Guaran effect on rat intestinal absorption. A perfusion study.
Gastroenterology.
1984 Apr; 86(4):645-53. doi:
10.1016/s0016-5085(84)80112-2
. [PMID: 6321290] - E C Foulkes. Nature of inhibition of renal aspartate reabsorption in experimental Fanconi syndrome.
Toxicology and applied pharmacology.
1983 Dec; 71(3):445-50. doi:
10.1016/0041-008x(83)90033-9
. [PMID: 6658792] - M A Gray, K J Micklem, F Brown, C A Pasternak. Effect of vesicular stomatitis virus and Semliki Forest Virus on uptake of nutrients and intracellular cation concentration.
The Journal of general virology.
1983 Jul; 64 (Pt 7)(?):1449-56. doi:
10.1099/0022-1317-64-7-1449
. [PMID: 6306146] - E W Chideckel, D Edwards. Non-metabolizable amino acids are potent stimulators of hepatic and renal ornithine decarboxylase activity.
The Biochemical journal.
1983 Feb; 210(2):617-9. doi:
10.1042/bj2100617
. [PMID: 6860314] - E C Foulkes, S Blanck. Mechanism of inhibition of renal amino acid reabsorption in rabbits by heavy metals.
Toxicology and applied pharmacology.
1982 Jun; 64(1):103-7. doi:
10.1016/0041-008x(82)90327-1
. [PMID: 7112573] - D W Barfuss, J A Schafer. Collection and analysis of absorbate from proximal straight tubules.
The American journal of physiology.
1981 Dec; 241(6):F597-604. doi:
10.1152/ajprenal.1981.241.6.f597
. [PMID: 7325231] - J M Lingard. The effect of changes in osmolality on amino acid transport in the proximal convoluted tubule of the rat kidney.
The Australian journal of experimental biology and medical science.
1981 Oct; 59(Pt 5):609-15. doi:
10.1038/icb.1981.53
. [PMID: 7325891] - M J Tisdale. Effect of methionine deprivation on S-adenosylmethionine decarboxylase of tumour cells.
Biochimica et biophysica acta.
1981 Jul; 675(3-4):366-72. doi:
10.1016/0304-4165(81)90027-1
. [PMID: 6268191] - M G Costantini, G S Johnson. Disproportionate accumulation of 18S and 28S ribosomal RNA in cultured normal rat kidney cells treated with picolinic acid or 5-methylnicotinamide.
Experimental cell research.
1981 Apr; 132(2):443-51. doi:
10.1016/0014-4827(81)90119-1
. [PMID: 6452285] - R Ahl. Effect of inhibitors of methylation on early and late interferon synthesis in bovine kidney cell cultures.
Journal of interferon research.
1981 Feb; 1(2):203-18. doi:
10.1089/jir.1981.1.203
. [PMID: 6180052] - A G Craan. Cystinuria: the disease and its models.
Life sciences.
1981 Jan; 28(1):5-22. doi:
10.1016/0024-3205(81)90360-x
. [PMID: 6783799] - C M Greco, H C Powell, R S Garrett, P W Lampert. Cycloleucine encephalopathy.
Neuropathology and applied neurobiology.
1980 Sep; 6(5):349-60. doi:
10.1111/j.1365-2990.1980.tb00671.x
. [PMID: 6256679] - H Hydén, P W Lange, S Larsson. S100-glia regulation of GABA transport across the nerve cell membrane.
Journal of the neurological sciences.
1980 Mar; 45(2-3):303-16. doi:
10.1016/0022-510x(80)90173-2
. [PMID: 7365505] - R Teschner, S Postius, M Löffler, F Schneider. Cell proliferation and metabolism of Ehrlich ascites tumor cells grown in chemically defined albumin medium for several passages.
Zeitschrift fur Naturforschung. Section C, Biosciences.
1980 Jan; 35(1-2):117-23. doi:
10.1515/znc-1980-1-222
. [PMID: 7405356] - A G Craan, M Bergeron. Nonparticipation of extracellular glutathione in renal transport of dibasic amino acids.
Canadian journal of physiology and pharmacology.
1979 Oct; 57(10):1168-71. doi:
10.1139/y79-172
. [PMID: 509369] - T C Rainbow, J B Flexner, L B Flexner, P L Hoffman, R Walter. Distribution, survival and biological effects in mice of a behaviorally active, enzymatically stable peptide: pharmacokinetics of cyclo(Leu-Gly) and puromycin-induced amnesia.
Pharmacology, biochemistry, and behavior.
1979 May; 10(5):787-93. doi:
10.1016/0091-3057(79)90334-4
. [PMID: 573901] - M Caboche, J Hatzfeld. Methionine metabolism in BHK cells: preliminary characterization of the physiological effects of cycloleucine, an inhibitor of s-adenosylmethionine biosynthesis.
Journal of cellular physiology.
1978 Dec; 97(3 Pt 1):361-70. doi:
10.1002/jcp.1040970311
. [PMID: 730775] - A G Craan, M Bergeron. Experimental cystinuria: the cycloleucine model. II. Amino acid efflux from intestinal and renal tissues.
Metabolism: clinical and experimental.
1978 Nov; 27(11):1613-25. doi:
10.1016/0026-0495(78)90284-6
. [PMID: 703604] - L C Washburn, T T Sun, J B Anon, R L Hayes. Effect of structure on tumor specificity of alicyclic alpha-amino acids.
Cancer research.
1978 Aug; 38(8):2271-3. doi:
. [PMID: 208763]
- N Moatti, M Feneant, F Lemonnier, M Gautier, A Lemonnier. Effect of cycloleucine on amino acid accumulation by human diploid fibroblasts.
Clinica chimica acta; international journal of clinical chemistry.
1978 Jun; 86(3):245-9. doi:
10.1016/0009-8981(78)90378-9
. [PMID: 668116] - P A Friedman, J Torretti. Regional glucose metabolism in the cat kidney in vivo.
The American journal of physiology.
1978 May; 234(5):F415-23. doi:
10.1152/ajprenal.1978.234.5.f415
. [PMID: 645912] - S Levine, R Sowinski. Synergistic suppression of the hyperacute form of experimental allergic encephalomyelitis by tilorone and cycloleucine.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1977 Dec; 156(3):457-60. doi:
10.3181/00379727-156-39956
. [PMID: 594075] - E Li, S Kronfeld. Effects of wheat germ agglutinin on membrane transport.
Biochimica et biophysica acta.
1977 Sep; 469(2):202-10. doi:
10.1016/0005-2736(77)90182-1
. [PMID: 561616] - M Burg, C Patlak, N Green, D Villey. Organic solutes in fluid absorption by renal proximal convoluted tubules.
The American journal of physiology.
1976 Aug; 231(2):627-37. doi:
10.1152/ajplegacy.1976.231.2.627
. [PMID: 961916] - R A Nixon. Neurotoxicity of a non-metabolizable amino acid, 1-aminocyclopentane-1-carboxylic acid: regional protein levels and lipid composition of nervous tissue.
Journal of neurochemistry.
1976 Jul; 27(1):237-44. doi:
10.1111/j.1471-4159.1976.tb01570.x
. [PMID: 956826] - R A Reynolds, S Segal. Regulatory characteristics of amino acid transport in newborn rat renal cortex cells.
Biochimica et biophysica acta.
1976 Mar; 426(3):513-25. doi:
10.1016/0005-2736(76)90395-3
. [PMID: 1268209]