Bis(2-ethylhexyl) phthalate (BioDeep_00000399859)

Main id: BioDeep_00000001128

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


Bis(2-ethylhexyl) phthalate

化学式: C24H38O4 (390.2769948)
中文名称: 邻苯二甲酸二辛酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC
InChI: InChI=1S/C24H38O4/c1-5-9-13-19(7-3)17-27-23(25)21-15-11-12-16-22(21)24(26)28-18-20(8-4)14-10-6-2/h11-12,15-16,19-20H,5-10,13-14,17-18H2,1-4H3

描述信息

D010968 - Plasticizers
DEHP (Bis(2-ethylhexyl) phthalate) is an endogenous metabolite.
DEHP (Bis(2-ethylhexyl) phthalate) is an endogenous metabolite.

同义名列表

4 个代谢物同义名

Bis(2-ethylhexyl) phthalate; Ergoplast FDO; ESBO-D 82; DEHP



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

14 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yu Hao, Xuan'en Tian, Fengmei Yan, Xiuqin Wang, Jing Huang, Ling Li. Effect of MEHP on testosterone synthesis via Sirt1/Foxo1/Rab7 signaling pathway inhibition of lipophagy in TM3 cells. Ecotoxicology and environmental safety. 2024 Jun; 277(?):116394. doi: 10.1016/j.ecoenv.2024.116394. [PMID: 38663197]
  • Kai Li, Yiping Zhang, Ludi Li, Kanglong Cui, Yingzi Li, Chunying Li, Yufei Dai, Wusheng Xiao, Qi Wang. Identification of sensitive endpoints for the assessment of phthalates-induced reproductive and developmental toxicity: A literature mining study. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024 Jun; 188(?):114686. doi: 10.1016/j.fct.2024.114686. [PMID: 38663762]
  • Xiaowen Sun, Xue Zhang, Zhi Li, Tan Wang, Jie Zeng, Yongxuan Liu, Zhe Li, Lin Li. Efficient remediation of di-(2-ethylhexyl) phthalate and plant-growth promotion with the application of a phosphate-solubilizing compound microbial agent. The Science of the total environment. 2024 May; 926(?):171904. doi: 10.1016/j.scitotenv.2024.171904. [PMID: 38527548]
  • Shucong Chen, Hang Liu, Yulian Sun, Shuxian Li, Yixuan Shi, Zhipeng Cheng, Hongkai Zhu, Hongwen Sun. Phthalate Biomarkers Composition in Relation to Fatty Liver: Evidence from Epidemiologic and in vivo studies. The Science of the total environment. 2024 May; 924(?):171607. doi: 10.1016/j.scitotenv.2024.171607. [PMID: 38461993]
  • Jiten Singh, Ashok Jangra, Dinesh Kumar. Recent advances in toxicological research of di-(2-ethylhexyl)-phthalate: Focus on endoplasmic reticulum stress pathway. Chemosphere. 2024 May; 356(?):141922. doi: 10.1016/j.chemosphere.2024.141922. [PMID: 38593956]
  • Gül Kaplan, Merih Beler, Ismail Ünal, Atakan Karagöz, Gizem Eğilmezer, Ünsal Veli Üstündağ, Derya Cansız, A Ata Alturfan, Ebru Emekli-Alturfan. Diethylhexyl phthalate exposure amplifies oxidant and inflammatory response in fetal hyperglycemia model predisposing insulin resistance in zebrafish embryos. Toxicology and industrial health. 2024 May; 40(5):232-243. doi: 10.1177/07482337241238475. [PMID: 38467557]
  • Xianxu Li, Shichang Hu, Nan Jiang, Xiangfeng Yao, Can Wang, Qian Wang, Zhongkang Yang, Jun Wang. Biotoxicity responses of zebrafish in environmentally relevant concentration of di (2-ethylhexyl) phthalate. Environmental toxicology and pharmacology. 2024 Apr; 107(?):104423. doi: 10.1016/j.etap.2024.104423. [PMID: 38521434]
  • Yu Zhu, Xiang-Yu Ma, Ling-Ge Cui, Ya-Ru Xu, Chen-Xi Li, Milton Talukder, Xue-Nan Li, Jin-Long Li. Di (2-ethylhexyl) phthalate induced lipophagy-related renal ferroptosis in quail (Coturnix japonica). The Science of the total environment. 2024 Apr; 919(?):170724. doi: 10.1016/j.scitotenv.2024.170724. [PMID: 38325449]
  • Yun Bo Zhang, Jiang Li Li, Jie Tian, Xiao Lin Na. Effect of Maternal DEHP Exposure on Lipid Metabolism in Adult Male Rats and the Antagonistic Effect of Genistein. Biomedical and environmental sciences : BES. 2024 Mar; 37(3):315-319. doi: 10.3967/bes2024.034. [PMID: 38582995]
  • Xia Wang, Dinggang Li, Xiangqin Zheng, Yifan Hong, Jie Zhao, Wei Deng, Mingxin Wang, Lianju Shen, Chunlan Long, Guanghui Wei, Shengde Wu. Di-(2-ethylhexyl) phthalate induces ferroptosis in prepubertal mouse testes via the lipid metabolism pathway. Environmental toxicology. 2024 Mar; 39(3):1747-1758. doi: 10.1002/tox.24065. [PMID: 38050670]
  • Xiaoping Liang, Jiehua Liang, Shengqi Zhang, Haowei Yan, Tiangang Luan. Di-2-ethylhexyl phthalate disrupts hepatic lipid metabolism in obese mice by activating the LXR/SREBP-1c and PPAR-α signaling pathways. The Science of the total environment. 2024 Mar; 914(?):169919. doi: 10.1016/j.scitotenv.2024.169919. [PMID: 38199361]
  • Yu-Shun Lu, Zheng-Bo Liu, Yan-Yang Xu, Ji-Yue Sha, Di Qu, Yin-Shi Sun. Uptake and accumulation of di(2-ethylhexyl) phthalate (DEHP) in a soil-ginseng system and toxicological mechanisms on ginseng (Panax ginseng C.A. Meyer). The Science of the total environment. 2024 Mar; 914(?):170040. doi: 10.1016/j.scitotenv.2024.170040. [PMID: 38215853]
  • Jawad Ali Shah, Saif Ullah, Deyun Chen, Jianping Wu. Di-(2-ethylhexyl) phthalate (DEHP) contamination suppressed soil microbial biomass carbon and mitigated CO2 emissions against the background of alfalfa from different soils. Ecotoxicology and environmental safety. 2024 Mar; 272(?):116073. doi: 10.1016/j.ecoenv.2024.116073. [PMID: 38335580]
  • Yiyun Liu, Naima Hamid, Rakia Manzoor, Bao-Fu Zhang, Yan-Ling Liao, Jin-Xia Wang, De-Sheng Pei. PPARβ/δ-ANGPTL4 axis mediates the promotion of mono-2-ethylhexyl phthalic acid on MYCN-amplified neuroblastoma development. The Science of the total environment. 2024 Feb; 912(?):168949. doi: 10.1016/j.scitotenv.2023.168949. [PMID: 38042186]
  • Kajal Gaur, Himanshi Varshney, Iqra Subhan, Javeria Fatima, Smita Jyoti, Yasir Hasan Siddique. Evaluation of Bis(2-ethylhexyl) phthalate toxicity on the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024 Feb; 184(?):114425. doi: 10.1016/j.fct.2023.114425. [PMID: 38160779]
  • Kévin Bernal, Charbel Touma, Béatrice Le-Grand, Sophie Rose, Selenay Degerli, Valentine Genêt, Dominique Lagadic-Gossmann, Xavier Coumoul, Corinne Martin-Chouly, Sophie Langouët, Etienne B Blanc. Assessment of endocrine disruptor impacts on lipid metabolism in a fatty acid-supplemented HepaRG human hepatic cell line. Chemosphere. 2024 Feb; 349(?):140883. doi: 10.1016/j.chemosphere.2023.140883. [PMID: 38092172]
  • Yang Yang, Yue Tao, Rongyi Yang, Xiaodong Yi, Guanyu Zhong, Yanyan Gu, Ying Zhang. Ca2+ homeostasis imbalance induced by Pparg: A key factor in di (2-ethylhexyl) phthalate (DEHP)-induced cardiac dysfunction in zebrafish larvae. The Science of the total environment. 2024 Jan; ?(?):170436. doi: 10.1016/j.scitotenv.2024.170436. [PMID: 38281650]
  • Sean M Harris, Anthony L Su, John F Dou, Rita Loch-Caruso, Elana R Elkin, Sammy Jaber, Kelly M Bakulski. Placental cell conditioned media modifies hematopoietic stem cell transcriptome invitro. Placenta. 2024 Jan; 145(?):117-125. doi: 10.1016/j.placenta.2023.12.016. [PMID: 38128222]
  • Fulya Dal Yöntem, Sinem Ayaz, Şeyma Bulut, Ebru Hacıosmanoğlu Aldoğan, Müfide Aydoğan Ahbab. Endoplasmic reticulum stress and pro-inflammatory responses induced by phthalate metabolites monoethylhexyl phthalate and monobutyl phthalate in 1.1B4 pancreatic beta cells. Toxicology. 2024 Jan; 501(?):153695. doi: 10.1016/j.tox.2023.153695. [PMID: 38048874]
  • Hung-Yuan Su, Ching-Shu Lai, Kuo-Hsin Lee, Yu-Wei Chiang, Chia-Chi Chen, Ping-Chi Hsu. Prenatal exposure to low-dose di-(2-ethylhexyl) phthalate (DEHP) induces potentially hepatic lipid accumulation and fibrotic changes in rat offspring. Ecotoxicology and environmental safety. 2024 Jan; 269(?):115776. doi: 10.1016/j.ecoenv.2023.115776. [PMID: 38056127]
  • Hao Cai, Ke Li, Yilin Yin, Xiaotong Ni, Shiwen Xu. Quercetin alleviates DEHP exposure-induced pyroptosis and cytokine expression changes in grass carp L8824 cell line by inhibiting ROS/MAPK/NF-κB pathway. Fish & shellfish immunology. 2023 Dec; 143(?):109223. doi: 10.1016/j.fsi.2023.109223. [PMID: 37972744]
  • Hao-Ran Wang, Mu-Zi Li, Jia-Gen Cui, Hao Zhang, Yi Zhao, Jin-Long Li. Lycopene Prevents Phthalate-Induced Cognitive Impairment via Modulating Ferroptosis. Journal of agricultural and food chemistry. 2023 Nov; 71(44):16727-16738. doi: 10.1021/acs.jafc.3c04801. [PMID: 37871231]
  • Minling Gao, Linsen Bai, Ling Xiao, Hongchang Peng, Qiaoting Chen, Weiwen Qiu, Zhengguo Song. Micro (nano)plastics and phthalate esters drive endophytic bacteria alteration and inhibit wheat root growth. The Science of the total environment. 2023 Oct; ?(?):167734. doi: 10.1016/j.scitotenv.2023.167734. [PMID: 37827310]
  • Hongping Liao, Dandan Gao, Chunmiao Kong, Muhammad Junaid, Ye Li, Xikun Chen, Qingzhi Zheng, Guanglong Chen, Jun Wang. Trophic transfer of nanoplastics and di(2-ethylhexyl) phthalate in a freshwater food chain (Chlorella Pyrenoidosa-Daphnia magna-Micropterus salmoides) induced disturbance of lipid metabolism in fish. Journal of hazardous materials. 2023 Oct; 459(?):132294. doi: 10.1016/j.jhazmat.2023.132294. [PMID: 37591169]
  • Heng Shi, Xinhai Zhao, Peng Qin, Xianling Zhou, Sisi Liu, Chuanchuan Sun, Qiuyu Cao, Shiping Zhu, Shengyun Sun. Green tea polyphenols alleviate kidney injury induced by di(2-ethylhexyl) phthalate in mice. American journal of nephrology. 2023 Sep; ?(?):. doi: 10.1159/000534106. [PMID: 37734331]
  • Heng Shi, Xin-Hai Zhao, Qin Peng, Xian-Ling Zhou, Si-Si Liu, Chuan-Chuan Sun, Qiu-Yu Cao, Shi-Ping Zhu, Sheng-Yun Sun. Green tea polyphenols alleviate di-(2-ethylhexyl) phthalate-induced liver injury in mice. World journal of gastroenterology. 2023 Sep; 29(34):5054-5074. doi: 10.3748/wjg.v29.i34.5054. [PMID: 37753369]
  • Shivani Popli Goyal, Chakkaravarthi Saravanan. An insight into the critical role of gut microbiota in triggering the phthalate-induced toxicity and its mitigation using probiotics. The Science of the total environment. 2023 Sep; 904(?):166889. doi: 10.1016/j.scitotenv.2023.166889. [PMID: 37683852]
  • Sabir Khan, Shafia Arshad, Imran Masood, Amina Arif, Saba Abbas, Asma Waheed Qureshi, Asia Parveen, Zeemal Seemab Ameen. GC-MS Analysis of Persicaria bistorta: Uncovering the Molecular Basis of Its Traditional Medicinal Use. Applied biochemistry and biotechnology. 2023 Jul; ?(?):. doi: 10.1007/s12010-023-04580-0. [PMID: 37515679]
  • Ayoub Kdimy, Seong Jong Kim, Zulfiqar Ali, Md Imdadul H Khan, Siddharth K Tripathi, Souad El Hajjaji, Hoang V Le. Isolation of Two Plasticizers, Bis(2-Ethylhexyl) Terephthalate and Bis(2-Ethylhexyl) Phthalate, from Capparis spinosa L. Leaves. Chemistry & biodiversity. 2023 Jul; ?(?):e202300903. doi: 10.1002/cbdv.202300903. [PMID: 37505806]
  • Fitra Fauziah, Hirowati Ali, Cimi Ilmiawati, Eko Fuji Ariyanto, Dwi Dinni Aulia Bakhtra, Deslina Setria Mita, Nova Syafni, Dian Handayani. Non-monotonic dose-response of di-(2-ethylhexyl) phthalate isolated from Penicillium citrinum XT6 on adipogenesis and expression of PPARγ and GLUT4 in 3T3-L1 adipocytes. Journal of complementary & integrative medicine. 2023 Jul; ?(?):. doi: 10.1515/jcim-2023-0137. [PMID: 37474486]
  • Sammani Ramanayaka, Meththika Vithanage, Hao Zhang, Kirk T Semple. Role of soil organic matter on the retention and mobility of common plastic additives, Di(2-ethylhexyl) phthalate, bisphenol A and benzophenone, in soil. Environmental research. 2023 Jul; 236(Pt 1):116725. doi: 10.1016/j.envres.2023.116725. [PMID: 37487922]
  • Chenghong Long, Zhenru Li, Shijin Liang, Sitong Yao, Songqi Zhu, Lin Lu, Rui Cao, Yingni Chen, Yuxin Huang, Yongjiang Ma, Wei Lei, Xiaohuan Liang. Resveratrol reliefs DEHP-induced defects during human decidualization. Ecotoxicology and environmental safety. 2023 Jun; 258(?):114931. doi: 10.1016/j.ecoenv.2023.114931. [PMID: 37121080]
  • Haoyan Xiao, Yanji Liu, Hanxia Yu, Niraj Yadav, Jing He, Lige Zhang, Wenbing Tan. Combined toxicity influence of polypropylene microplastics and di-2-ethylhexyl phthalate on physiological-biochemical characteristics of cucumber (Cucumis sativus L.). Plant physiology and biochemistry : PPB. 2023 Jun; 201(?):107811. doi: 10.1016/j.plaphy.2023.107811. [PMID: 37307719]
  • Wenjie Ren, Rui Zhao, Ying Teng, Yongming Luo. Collection of Alfalfa Root Exudates to Study the Impact of Di(2-ethylhexyl) Phthalate on Metabolite Production. Journal of visualized experiments : JoVE. 2023 06; ?(196):. doi: 10.3791/64470. [PMID: 37335114]
  • Huanhuan Xing, Xiaolong Yu, Jianteng Sun, Guining Lu, Minghan Zhu, Jiahao Liang, Ling Jin, Lizhong Zhu. Interaction between Phthalate Ester and Rice Plants: Novel Transformation Pathways and Metabolic-Network Perturbations. Environmental science & technology. 2023 Jun; ?(?):. doi: 10.1021/acs.est.2c09737. [PMID: 37260373]
  • Hang Liu, Hongyang Cui, Yixuan Huang, Yi Yang, Ling Jiao, Yulan Zhou, Jianying Hu, Yi Wan. Enzyme-Catalyzed Hydrogen-Deuterium Exchange between Environmental Pollutants and Enzyme-Regulated Endogenous Metabolites. Environmental science & technology. 2023 05; 57(17):6844-6853. doi: 10.1021/acs.est.2c08056. [PMID: 37080910]
  • Qi Xu, Shuang Ding, Wen Qi, Xueting Zhang, Meng Zhang, Jiqiang Xing, Aipeng Ju, Liting Zhou, Lin Ye. JAK3/STAT5b/PPARγ Pathway Mediates the Association between Di(2-ethylhexyl) Phthalate Exposure and Lipid Metabolic Disorder in Chinese Adolescent Students. Chemical research in toxicology. 2023 Apr; ?(?):. doi: 10.1021/acs.chemrestox.2c00365. [PMID: 37093692]
  • Juan Wu, Yugang Lai, Haofeng Zhu, Xindong Yang, Xintao Ye, Anping Zhang, Jianqiang Sun. Phthalate esters and their metabolites in paired soil-crop systems from farmland in major provinces of eastern China: Pollution characteristics and implications for human exposure. The Science of the total environment. 2023 Apr; 882(?):163645. doi: 10.1016/j.scitotenv.2023.163645. [PMID: 37088394]
  • L Earl Gray. Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats. Toxicology and applied pharmacology. 2023 04; 465(?):116454. doi: 10.1016/j.taap.2023.116454. [PMID: 36921846]
  • Jones B Graceli, Charles S da Costa, Mary J Laws, Ashley R K Deviney, Daryl Meling, Jodi A Flaws. Chronic exposure to a mixture of phthalates shifts the white and brown adipose tissue phenotype in female mice. Toxicological sciences : an official journal of the Society of Toxicology. 2023 Apr; ?(?):. doi: 10.1093/toxsci/kfad032. [PMID: 37021957]
  • Huiyan Yang, Mingsheng Li, Cui Zhang, Na Li, Xiangfeng Yao, Xianxu Li, Fang Li, Jun Wang. Ecotoxicological and biochemical effects of di(2-ethylhexyl)phthalate on wheat (Jimai 22, Triticum aestivum L.). Journal of hazardous materials. 2023 04; 447(?):130816. doi: 10.1016/j.jhazmat.2023.130816. [PMID: 36680896]
  • Xiaolong Yu, Huanhuan Xing, Jianteng Sun, Xiaodong Du, Guining Lu, Lizhong Zhu. New insight into phytometabolism and phytotoxicity mechanism of widespread plasticizer di (2-ethylhexyl) phthalate in rice plants. The Science of the total environment. 2023 Apr; 880(?):163254. doi: 10.1016/j.scitotenv.2023.163254. [PMID: 37019237]
  • Rui Wang, Jingyue Chen, Zhaokang Cui, Yu Li, Qian Gao, Yilong Miao, Huili Wang, Bo Xiong. Exposure to diisononyl phthalate deteriorates the quality of porcine oocytes by inducing the apoptosis. Ecotoxicology and environmental safety. 2023 Apr; 254(?):114768. doi: 10.1016/j.ecoenv.2023.114768. [PMID: 36917878]
  • Xianxu Li, Min'an Li, Nan Jiang, Xiangfeng Yao, Qian Wang, Huijuan Lv, Can Wang, Jun Wang. Evaluation of soil ecological health after exposure to environmentally relevant doses of Di (2-ethylhexyl) phthalate: Insights from toxicological studies of earthworms at different ecological niches. Environmental pollution (Barking, Essex : 1987). 2023 Apr; 322(?):121204. doi: 10.1016/j.envpol.2023.121204. [PMID: 36754202]
  • Qiang-Qiang Shi, Xiao-Qian Zhang, Ze-Ming Zhang, Ning-Bo Wang, Hua Liu, Rong-Rong Zhang, Ai-Li Sun, Jiong Chen, Xi-Zhi Shi. Transcriptome sequencing and metabolite analysis reveal the single and combined effects of microplastics and di-(2-ethylhexyl) phthalate on Peneaus vannamei. The Science of the total environment. 2023 Apr; 867(?):161549. doi: 10.1016/j.scitotenv.2023.161549. [PMID: 36640892]
  • Yuezhu Zhang, Honghao Qian, Jia Wang, Ying Zhu, Xiaohan Miao, Xu Li, Jianli Yin, Ruxuan Zhang, Jiaming Ye, Chuanyi Huo, Weisen Zhao, Lin Ye. Di-(2-ethylhexyl) phthalate (DEHP) promoted hepatic lipid accumulation by activating Notch signaling pathway. Environmental toxicology. 2023 Mar; ?(?):. doi: 10.1002/tox.23792. [PMID: 36988346]
  • Zongyi Sun, Dejun Li, Haibin Wang, Yu Ding, Chun Zhang, Shuyue Wang, Xuejiao Wang, Bingxin Li, Danning Xu. Polysaccharide of Atractylodes macrocephala Koidz(PAMK) protects against DEHP-induced apoptosis in grass carp hepatocytes. Fish & shellfish immunology. 2023 Mar; 134(?):108587. doi: 10.1016/j.fsi.2023.108587. [PMID: 36773714]
  • Yifan Zhang, Heping Feng, Ao Tian, Cuili Zhang, Fuyong Song, Tao Zeng, Xiulan Zhao. Long-term exposure to low-dose Di(2-ethylhexyl) phthalate aggravated high fat diet-induced obesity in female mice. Ecotoxicology and environmental safety. 2023 Feb; 253(?):114679. doi: 10.1016/j.ecoenv.2023.114679. [PMID: 36841080]
  • Samuel Thomas, William A Ricke, Lingjun Li. Toxicoproteomics of Mono(2-ethylhexyl) phthalate and Perfluorooctanesulfonic Acid in Models of Prostatic Diseases. Chemical research in toxicology. 2023 Feb; 36(2):251-259. doi: 10.1021/acs.chemrestox.2c00328. [PMID: 36749316]
  • Dan Zhang, Kai Zhou, Chenqi Liu, Xiujuan Li, Siyi Pan, Lan Zhong. Dissipation, uptake, translocation and accumulation of five phthalic acid esters in sediment-Zizania latifolia system. Chemosphere. 2023 Feb; 315(?):137651. doi: 10.1016/j.chemosphere.2022.137651. [PMID: 36584829]
  • Yi Zhao, Hao Zhang, Jia-Gen Cui, Jia-Xin Wang, Ming-Shan Chen, Hao-Ran Wang, Xue-Nan Li, Jin-Long Li. Ferroptosis is critical for phthalates driving the blood-testis barrier dysfunction via targeting transferrin receptor. Redox biology. 2023 02; 59(?):102584. doi: 10.1016/j.redox.2022.102584. [PMID: 36580806]
  • You-Lin Tain, Chih-Yao Hou, Guo-Ping Chang-Chien, Sufan Lin, Chien-Ning Hsu. Resveratrol Butyrate Ester Supplementation Blunts the Development of Offspring Hypertension in a Maternal Di-2-ethylhexyl Phthalate Exposure Rat Model. Nutrients. 2023 Jan; 15(3):. doi: 10.3390/nu15030697. [PMID: 36771404]
  • Lucas Panneel, Paulien Cleys, Camille Breugelmans, Christina Christia, Govindan Malarvannan, Giulia Poma, Philippe G Jorens, Antonius Mulder, Adrian Covaci. Neonatal exposure to phthalate and alternative plasticizers via parenteral nutrition. International journal of pharmaceutics. 2023 Jan; 631(?):122472. doi: 10.1016/j.ijpharm.2022.122472. [PMID: 36526146]
  • Jia-Xin Wang, Yi Zhao, Ming-Shan Chen, Hao Zhang, Jia-Gen Cui, Jin-Long Li. Heme-oxygenase-1 as a target for phthalate-induced cardiomyocytes ferroptosis. Environmental pollution (Barking, Essex : 1987). 2023 Jan; 317(?):120717. doi: 10.1016/j.envpol.2022.120717. [PMID: 36423886]
  • Ralph E T Vanstreels, Isadora N L Piccinin, Marcelo Maraschin, Luciana Gallo, Patricia P Serafini, Alice Pereira, Allan P Santos, Leandro Egert, Marcela M Uhart. PHTHALATE ESTERS (PLASTICIZERS) IN THE UROPYGIAL GLAND AND THEIR RELATIONSHIP TO PLASTICS INGESTION IN SEABIRDS ALONG THE COAST OF ESPÍRITO SANTO, EASTERN BRAZIL. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2023 Jan; 53(4):733-743. doi: 10.1638/2022-0053. [PMID: 36640075]
  • Yu-Ri Kim, Mee Kyung Sang. Effects of di-(2-ethylhexyl) phthalate on growth, metabolism, and virulence of the plant pathogenic bacterium Acidovorax citrulli. Frontiers in cellular and infection microbiology. 2023; 13(?):1228713. doi: 10.3389/fcimb.2023.1228713. [PMID: 37692166]
  • Long Wang, Jianyong Li, Jiazuo Zheng, Jing Liang, Rongli Li, Zhenbin Gong. Source tracing and health risk assessment of phthalate esters in household tap-water: A case study of the urban area of Quanzhou, Southeast China. Ecotoxicology and environmental safety. 2022 Dec; 248(?):114277. doi: 10.1016/j.ecoenv.2022.114277. [PMID: 36371886]
  • Hannah Gardener, Chela Wallin, Jaclyn Bowen. Heavy metal and phthalate contamination and labeling integrity in a large sample of US commercially available cannabidiol (CBD) products. The Science of the total environment. 2022 Dec; 851(Pt 1):158110. doi: 10.1016/j.scitotenv.2022.158110. [PMID: 35987236]
  • Xiao Gu, Haixia Liu, Wei Luo, Xietong Wang, Hongying Wang, Lei Li. Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP/PKA signaling pathway in human trophoblastic HTR-8/Svneo cells. Reproductive toxicology (Elmsford, N.Y.). 2022 12; 114(?):22-31. doi: 10.1016/j.reprotox.2022.10.001. [PMID: 36206922]
  • Juan Cruz Carrizo, Sung Vo Duy, Gabriel Munoz, Guido Marconi, María Valeria Amé, Sébastien Sauvé. Suspect screening of pharmaceuticals, illicit drugs, pesticides, and other emerging contaminants in Argentinean Piaractus mesopotamicus, a fish species used for local consumption and export. Chemosphere. 2022 Dec; 309(Pt 1):136769. doi: 10.1016/j.chemosphere.2022.136769. [PMID: 36209849]
  • Chao Liu, Qin Qin, Jinghan Xu, Ximing Li, Hongliang Cong. Phthalate promotes atherosclerosis through interacting with long-non coding RNA and induces macrophage foam cell formation and vascular smooth muscle damage. Chemosphere. 2022 Dec; 308(Pt 2):136383. doi: 10.1016/j.chemosphere.2022.136383. [PMID: 36088979]
  • Anran Liu, Wenjing Wang, Xiancao Chen, Xiaoyan Zheng, Wenting Fu, Gang Wang, Jing Ji, Chunfeng Guan. Phytoremediation of DEHP and heavy metals co-contaminated soil by rice assisted with a PGPR consortium: Insights into the regulation of ion homeostasis, improvement of photosynthesis and enrichment of beneficial bacteria in rhizosphere soil. Environmental pollution (Barking, Essex : 1987). 2022 Dec; 314(?):120303. doi: 10.1016/j.envpol.2022.120303. [PMID: 36181940]
  • Longfei Jiang, Xiaoping Zhu, Chunling Luo, Dandan Song, Mengke Song. The synergistic toxicity effect of di(2-ethylhexyl)phthalate and plant growth disturbs the structure and function of soil microbes in the rhizosphere. Environment international. 2022 12; 170(?):107629. doi: 10.1016/j.envint.2022.107629. [PMID: 36395556]
  • Chenming Zhang, Shiqi Wang, Zulong Wang, Qi Zhang, Rubing Chen, Hao Zhang, Zhong Hua, Sicheng Ma. Repair mechanism of Wuwei Fuzheng Yijing formula in di-2-ethylhexyl phthalate-induced sperm DNA fragmentation in mice. Pharmaceutical biology. 2022 Dec; 60(1):1286-1302. doi: 10.1080/13880209.2022.2089694. [PMID: 35797467]
  • Ryan S Babadi, Anne M Riederer, Paul D Sampson, Sheela Sathyanarayana, Terrance J Kavanagh, Jennifer E Krenz, Syam S Andra, Seunghee Kim-Schulze, Karen L Jansen, Elizabeth Torres, Adriana Perez, Lisa R Younglove, Maria I Tchong-French, Catherine J Karr. Associations between repeated measures of urinary phthalate metabolites and biomarkers of oxidative stress in a rural agricultural cohort of children with asthma. The Science of the total environment. 2022 Nov; 848(?):157493. doi: 10.1016/j.scitotenv.2022.157493. [PMID: 35878846]
  • Chenchen Wang, Yaqi Guo, Lixia Feng, Weiliang Pang, Jingjie Yu, Shaopo Wang, Chunsheng Qiu, Chaocan Li, Yufei Wang. Fate of phthalates in a river receiving wastewater treatment plant effluent based on a multimedia model. Water science and technology : a journal of the International Association on Water Pollution Research. 2022 Nov; 86(9):2124-2137. doi: 10.2166/wst.2022.347. [PMID: 36378170]
  • Nadeem G Khan, Sangavi Eswaran, Divya Adiga, S Sriharikrishnaa, Sanjiban Chakrabarty, Padmalatha S Rai, Shama Prasada Kabekkodu. Integrated bioinformatic analysis to understand the association between phthalate exposure and breast cancer progression. Toxicology and applied pharmacology. 2022 Nov; 457(?):116296. doi: 10.1016/j.taap.2022.116296. [PMID: 36328110]
  • Qiong Liu, Chang Liu, Zhe Zhao, Shu-Xuan Liang. Prioritization of micropollutants in municipal wastewater and the joint inhibitory effects of priority organic pollutants on Vibrio qinghaiensis sp.-Q67. Aquatic toxicology (Amsterdam, Netherlands). 2022 Nov; 252(?):106288. doi: 10.1016/j.aquatox.2022.106288. [PMID: 36156356]
  • Ming-Huang Wang, Chih-Feng Chen, Frank Paolo Jay B Albarico, Chiu-Wen Chen, Cheng-Di Dong. Occurrence and distribution of phthalate esters and microplastics in wastewater treatment plants in Taiwan and their toxicological risks. Chemosphere. 2022 Nov; 307(Pt 2):135857. doi: 10.1016/j.chemosphere.2022.135857. [PMID: 35940417]
  • Yingjie Liu, Zhongxiang Chen, Shanwei Li, Lu Ding, Xiaofeng Wei, Shicheng Han, Peng Wang, Yanchun Sun. Multi-omics profiling and biochemical assays reveal the acute toxicity of environmental related concentrations of Di-(2-ethylhexyl) phthalate (DEHP) on the gill of crucian carp (Carassius auratus). Chemosphere. 2022 Nov; 307(Pt 2):135814. doi: 10.1016/j.chemosphere.2022.135814. [PMID: 35921887]
  • Xiangjuan Wei, Daqian Yang, Boya Zhang, Xingpei Fan, Haining Du, Ruijiao Zhu, Xiaotong Sun, Meimei Zhao, Ning Gu. Di-(2-ethylhexyl) phthalate increases plasma glucose and induces lipid metabolic disorders via FoxO1 in adult mice. The Science of the total environment. 2022 Oct; 842(?):156815. doi: 10.1016/j.scitotenv.2022.156815. [PMID: 35750186]
  • Haifeng Sun, Chunli Lei, Yihao Yuan, Jianhong Xu, Ming Han. Nanoplastic impacts on the foliar uptake, metabolism and phytotoxicity of phthalate esters in corn (Zea mays L.) plants. Chemosphere. 2022 Oct; 304(?):135309. doi: 10.1016/j.chemosphere.2022.135309. [PMID: 35709832]
  • Bélinda Crobeddu, Antoine Jutras-Carignan, Élise Kolasa, Catherine Mounier, Bernard Robaire, Isabelle Plante. Gestational and Lactational Exposure to the Emergent Alternative Plasticizer 1,2-Cyclohexane Dicarboxylic Acid Diisononyl Ester (DINCH) Impairs Lipid Metabolism to a Greater Extent Than the Commonly Used Di(2-Ethylhexyl) Phthalate (DEHP) in the Adult Rat Mammary Gland. Toxicological sciences : an official journal of the Society of Toxicology. 2022 09; 189(2):268-286. doi: 10.1093/toxsci/kfac076. [PMID: 35861430]
  • Senyuan Huang, Shengtao Ma, Dongwu Wang, Hongli Liu, Guiying Li, Yingxin Yu. National-scale urinary phthalate metabolites in the general urban residents involving 26 provincial capital cities in China and the influencing factors as well as non-carcinogenic risks. The Science of the total environment. 2022 Sep; 838(Pt 2):156062. doi: 10.1016/j.scitotenv.2022.156062. [PMID: 35597362]
  • Pengfei Hou, Wenting Dai, Yanshan Jin, Fengqi Zhao, Jianxin Liu, Hongyun Liu. Maternal exposure to di-2-ethylhexyl phthalate (DEHP) depresses lactation capacity in mice. The Science of the total environment. 2022 Sep; 837(?):155813. doi: 10.1016/j.scitotenv.2022.155813. [PMID: 35550907]
  • Ruxianguli Aimuzi, Senyuan Huang, Kai Luo, Shengtao Ma, Xiaona Huo, Guiying Li, Ying Tian, Jun Zhang, Yingxin Yu. Levels and health risks of urinary phthalate metabolites and the association between phthalate exposure and unexplained recurrent spontaneous abortion: a large case-control study from China. Environmental research. 2022 09; 212(Pt C):113393. doi: 10.1016/j.envres.2022.113393. [PMID: 35504341]
  • Hongxiu Liu, Yuyan Wang, Kurunthachalam Kannan, Mengling Liu, Hongkai Zhu, Yu Chen, Linda G Kahn, Melanie H Jacobson, Bo Gu, Shilpi Mehta-Lee, Sara G Brubaker, Akhgar Ghassabian, Leonardo Trasande. Determinants of phthalate exposures in pregnant women in New York City. Environmental research. 2022 09; 212(Pt A):113203. doi: 10.1016/j.envres.2022.113203. [PMID: 35358547]
  • Taylor M Etzel, Joseph M Braun, Jordan R Kuiper, Antonia M Calafat, Kim M Cecil, Aimin Chen, Bruce P Lanphear, Kimberly Yolton, Heidi J Kalkwarf, Jessie P Buckley. Gestational and childhood phthalate exposures and adolescent body composition: The HOME study. Environmental research. 2022 Sep; 212(Pt B):113320. doi: 10.1016/j.envres.2022.113320. [PMID: 35461845]
  • Jane S Burns, Oleg Sergeyev, Mary M Lee, Paige L Williams, Lidia Mínguez-Alarcón, Bora Plaku-Alakbarova, Sergey Sokolov, Sergey Kovalev, Holger M Koch, Albert T Lebedev, Russ Hauser, Susan A Korrick. Associations of prepubertal urinary phthalate metabolite concentrations with pubertal onset among a longitudinal cohort of boys. Environmental research. 2022 09; 212(Pt A):113218. doi: 10.1016/j.envres.2022.113218. [PMID: 35390299]
  • Fatima Iram, Sajida Batool, Sitara Shameem, Iqra Aslam, Saira Batool, Marrium Shaheen, Riqza Aziz. Effect of aqueous garlic (Allium sativum) extract against di-(2-ethylhexyl) phthalate induced reproductive toxicity in male mice. Andrologia. 2022 Sep; 54(8):e14480. doi: 10.1111/and.14480. [PMID: 35670728]
  • Fuxin Huang, Rui Guan, Jingyi Wang, Lei Wang, Ying Zhang, Shiyu Wang, Lei Wang, Jianhua Qu, Maofeng Dong, Shaowen Rong. Interference between di(2-ethylhexyl) phthalate and heavy metals (Cd and Cu) in a Mollisol during aging and mobilization. The Science of the total environment. 2022 Aug; 836(?):155635. doi: 10.1016/j.scitotenv.2022.155635. [PMID: 35513158]
  • Md Saidur Rahman, Won-Ki Pang, Shehreen Amjad, Do-Yeal Ryu, Elikanah Olusayo Adegoke, Yoo-Jin Park, Myung-Geol Pang. Hepatic consequences of a mixture of endocrine-disrupting chemicals in male mice. Journal of hazardous materials. 2022 08; 436(?):129236. doi: 10.1016/j.jhazmat.2022.129236. [PMID: 35739755]
  • Chun Ming How, Vivian Hsiu-Chuan Liao. Chronic exposure to environmentally relevant levels of di(2-ethylhexyl) phthalate (DEHP) disrupts lipid metabolism associated with SBP-1/SREBP and ER stress in C. elegans. Environmental pollution (Barking, Essex : 1987). 2022 Aug; 307(?):119579. doi: 10.1016/j.envpol.2022.119579. [PMID: 35671893]
  • Huanhuan Xing, Xiaolong Yu, Jiahui Huang, Xiaodong Du, Mengting Wang, Jianteng Sun, Guining Lu, Xueqin Tao. Characteristics and Health Risks of Phthalate Ester Contamination in Soil and Plants in Coastal Areas of South China. International journal of environmental research and public health. 2022 08; 19(15):. doi: 10.3390/ijerph19159516. [PMID: 35954873]
  • B Ogunlade, S C Gbotolorun, O A Adedotun, K A Itiere, J A Adejayi. VANILLIC ACID AND VITAMIN C ATTENUATED DEHP-INDUCED TESTICULAR TOXICITY IN MALE RATS. Reproduction & fertility. 2022 Aug; ?(?):. doi: 10.1530/raf-22-0045. [PMID: 35980228]
  • Saira Batool, Sajida Batool, Sitara Shameem, Tahira Batool, Saima Batool. Effects of dibutyl phthalate and di (2-ethylhexyl) phthalate on hepatic structure and function of adult male mice. Toxicology and industrial health. 2022 Aug; 38(8):470-480. doi: 10.1177/07482337221108578. [PMID: 35700117]
  • Hyunki Cho, Yohan Seol, Seungyun Baik, Baeckkyoung Sung, Chang Seon Ryu, Young Jun Kim. Mono(2-ethylhexyl) phthalate modulates lipid accumulation and reproductive signaling in Daphnia magna. Environmental science and pollution research international. 2022 Aug; 29(37):55639-55650. doi: 10.1007/s11356-022-19701-1. [PMID: 35320476]
  • Qian Chen, Qingmin Kong, Peijun Tian, Yufeng He, Jianxin Zhao, Hao Zhang, Gang Wang, Wei Chen. Lactic acid bacteria alleviate di-(2-ethylhexyl) phthalate-induced liver and testis toxicity via their bio-binding capacity, antioxidant capacity and regulation of the gut microbiota. Environmental pollution (Barking, Essex : 1987). 2022 Jul; 305(?):119197. doi: 10.1016/j.envpol.2022.119197. [PMID: 35378196]
  • Yue-Qiang Huang, Yi-Xi Tang, Bai-Hao Qiu, Milton Talukder, Xue-Nan Li, Jin-Long Li. Di-2-ethylhexyl phthalate (DEHP) induced lipid metabolism disorder in liver via activating the LXR/SREBP-1c/PPARα/γ and NF-κB signaling pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022 Jul; 165(?):113119. doi: 10.1016/j.fct.2022.113119. [PMID: 35537648]
  • Hongping Liao, Shulin Liu, Muhammad Junaid, Dandan Gao, Wenjie Ai, Guanglong Chen, Jun Wang. Di-(2-ethylhexyl) phthalate exacerbated the toxicity of polystyrene nanoplastics through histological damage and intestinal microbiota dysbiosis in freshwater Micropterus salmoides. Water research. 2022 Jul; 219(?):118608. doi: 10.1016/j.watres.2022.118608. [PMID: 35605397]
  • Jordan R Kuiper, Katie M O'Brien, Barrett M Welch, Emily S Barrett, Ruby H N Nguyen, Sheela Sathyanarayana, Ginger L Milne, Shanna H Swan, Kelly K Ferguson, Jessie P Buckley. Combining Urinary Biomarker Data From Studies With Different Measures of Urinary Dilution. Epidemiology (Cambridge, Mass.). 2022 Jul; 33(4):533-540. doi: 10.1097/ede.0000000000001496. [PMID: 35473917]
  • Tsu-I Hsia, Po-Chin Huang, Hsin-Chang Chen, Yuan-Ting C Lo, Wan-Ting Chang, Yann-Yuh Jou, Han-Bin Huang. Relationships among phthalate exposure, oxidative stress, and insulin resistance in young military soldiers: A cumulative risk assessment and mediation approach. Environment international. 2022 07; 165(?):107316. doi: 10.1016/j.envint.2022.107316. [PMID: 35635958]
  • Zhaoqing Lyu, Kouji H Harada, Sungmin Kim, Tomoko Fujitani, Yang Cao, Toshiaki Hitomi, Yukiko Fujii, Younglim Kho, Kyungho Choi. Exposure to phthalate esters in Japanese females in Kyoto, Japan from 1993 to 2016: Temporal trends and associated health risks. Environment international. 2022 07; 165(?):107288. doi: 10.1016/j.envint.2022.107288. [PMID: 35588674]
  • Wei-Jie Wang, Chia-Sung Wang, Chi-Kang Wang, An-Ming Yang, Chien-Yu Lin. Urine Di-(2-ethylhexyl) Phthalate Metabolites Are Independently Related to Body Fluid Status in Adults: Results from a U.S. Nationally Representative Survey. International journal of environmental research and public health. 2022 Jun; 19(12):. doi: 10.3390/ijerph19126964. [PMID: 35742214]
  • Ling Yang, Liping Jiang, Xiance Sun, Jing Li, Ningning Wang, Xiaofang Liu, Xiaofeng Yao, Cong Zhang, Haoyuan Deng, Shaopeng Wang, Guang Yang. DEHP induces ferroptosis in testes via p38α-lipid ROS circulation and destroys the BTB integrity. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022 Jun; 164(?):113046. doi: 10.1016/j.fct.2022.113046. [PMID: 35447293]
  • Dongxu Han, Yujie Yao, Lu Chen, Zhiying Miao, Shiwen Xu. Apigenin ameliorates di(2-ethylhexyl) phthalate-induced ferroptosis: The activation of glutathione peroxidase 4 and suppression of iron intake. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022 Jun; 164(?):113089. doi: 10.1016/j.fct.2022.113089. [PMID: 35500696]
  • Sori Mok, Jae-Eun Lim, Aram Lee, Sungmin Kim, Sunmi Kim, Inae Lee, Younglim Kho, Jeongim Park, Sungkyoon Kim, Kyungho Choi, Hyo-Bang Moon. Within- and between-person variability of urinary phthalate metabolites and bisphenol analogues over seven days: Considerations of biomonitoring study design. Environmental research. 2022 06; 209(?):112885. doi: 10.1016/j.envres.2022.112885. [PMID: 35131323]
  • Alexandra Schaffert, Isabel Karkossa, Elke Ueberham, Rita Schlichting, Katharina Walter, Josi Arnold, Matthias Blüher, John T Heiker, Jörg Lehmann, Martin Wabitsch, Beate I Escher, Martin von Bergen, Kristin Schubert. Di-(2-ethylhexyl) phthalate substitutes accelerate human adipogenesis through PPARγ activation and cause oxidative stress and impaired metabolic homeostasis in mature adipocytes. Environment international. 2022 06; 164(?):107279. doi: 10.1016/j.envint.2022.107279. [PMID: 35567983]
  • Yujia Shen, Zhaoyang Jiang, Xinyi Zhong, Hemei Wang, Yutian Liu, Xinyi Li. Manipulation of cadmium and diethylhexyl phthalate on Rana chensinensis tadpoles affects the intestinal microbiota and fatty acid metabolism. The Science of the total environment. 2022 May; 821(?):153455. doi: 10.1016/j.scitotenv.2022.153455. [PMID: 35093358]