aminoglutethimide (BioDeep_00000398945)
Main id: BioDeep_00000006551
natural product
代谢物信息卡片
Aminoglutethimide (Cytadren)
化学式: C13H16N2O2 (232.1212)
中文名称: 氨鲁米特, 氨基谷氨酰胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1(=CC=C(C=C1)N)C2(CCC(NC2=O)=O)CC
InChI: InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)
描述信息
L - Antineoplastic and immunomodulating agents > L02 - Endocrine therapy > L02B - Hormone antagonists and related agents > L02BG - Aromatase inhibitors
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D065088 - Steroid Synthesis Inhibitors
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D004965 - Estrogen Antagonists
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor
D004791 - Enzyme Inhibitors > D065088 - Steroid Synthesis Inhibitors > D047072 - Aromatase Inhibitors
C274 - Antineoplastic Agent > C129818 - Antineoplastic Hormonal/Endocrine Agent > C481 - Antiestrogen
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C1740 - Aromatase Inhibitor
C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist > C2355 - Anti-Adrenal
C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor
D000970 - Antineoplastic Agents
同义名列表
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:2654
- KEGG: C07617
- KEGGdrug: D00574
- KEGGdrug: D88489
- PubChem: 2145
- DrugBank: DB00357
- ChEMBL: CHEMBL488
- MeSH: Aminoglutethimide
- CAS: 125-84-8
- MoNA: CCMSLIB00000078234
- PubChem: 9819
- NIKKAJI: J5.378C
- KNApSAcK: 2654
- LOTUS: LTS0063950
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
9 个相关的物种来源信息
- 66379 - Broussonetia: LTS0063950
- 172644 - Broussonetia papyrifera: 10.1021/NP010288L
- 172644 - Broussonetia papyrifera: LTS0063950
- 2759 - Eukaryota: LTS0063950
- 3398 - Magnoliopsida: LTS0063950
- 3487 - Moraceae: LTS0063950
- 35493 - Streptophyta: LTS0063950
- 58023 - Tracheophyta: LTS0063950
- 33090 - Viridiplantae: LTS0063950
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Fenglin Luo, Yoshiaki Manse, Saowanee Chaipech, Yutana Pongpiriyadacha, Osamu Muraoka, Toshio Morikawa. Phytochemicals with Chemopreventive Activity Obtained from the Thai Medicinal Plant Mammea siamensis (Miq.) T. Anders.: Isolation and Structure Determination of New Prenylcoumarins with Inhibitory Activity against Aromatase.
International journal of molecular sciences.
2022 Sep; 23(19):. doi:
10.3390/ijms231911233. [PMID: 36232534] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Long Zhao, Mei-Hong Chai, Hong-Fei Yao, Yan-Ping Huang, Zhao-Sheng Liu. Molecularly Imprinted Polymers Doped with Carbon Nanotube with Aid of Metal-Organic Gel for Drug Delivery Systems.
Pharmaceutical research.
2020 Sep; 37(10):193. doi:
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Physiological research.
2020 07; 69(3):415-426. doi:
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Molecular pharmacology.
2019 11; 96(5):629-640. doi:
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Molecular human reproduction.
2018 01; 24(1):2-13. doi:
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Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2017 Sep; 69(7):424-429. doi:
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2007 Feb; 192(2):453-8. doi:
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2006 Jul; 22(1):62-8. doi:
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2006 Apr; 69(4):700-3. doi:
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2006 Jan; 142(1):1-8. doi:
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2005 Dec; 78(1-4):67-81. doi:
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2004 Nov; 91(9):1703-10. doi:
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Anti-cancer drugs.
2004 Oct; 15(9):843-7. doi:
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2004 Sep; 2(1):2-7. doi:
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2004 May; 58(4):255-9. doi:
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2003 Aug; 196(2):319-25. doi:
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2003 Jul; 178(1):127-35. doi:
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International journal of oncology.
2003 May; 22(5):1081-9. doi:
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Psychopharmacology.
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Life sciences.
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Urology.
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Biology of reproduction.
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2001 Jun; 20(2):175-82. doi:
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2001 May; 169(2):321-31. doi:
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