5-hydroxylysine (BioDeep_00000398026)

Main id: BioDeep_00000001264

Secondary id: BioDeep_00000398318, BioDeep_00000400341, BioDeep_00000402979

natural product PANOMIX_OTCML-2023


代谢物信息卡片


L-Erythro-5-hydroxylysine

化学式: C6H14N2O3 (162.1004374)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 0.44%

分子结构信息

SMILES: C(CC(C(=O)O)N)C(CN)O
InChI: InChI=1S/C6H14N2O3/c7-3-4(9)1-2-5(8)6(10)11/h4-5,9H,1-3,7-8H2,(H,10,11)

描述信息

The lysine derivative that is 2,6-diamino-5-hydroxyhexanoic acid, a chiral alpha-amino acid.
KEIO_ID H064

同义名列表

5 个代谢物同义名

5-hydroxylysine; L-Erythro-5-hydroxylysine; (5R)-5-Hydroxy-L-lysine; 5-Hydroxy-L-lysine; L-hydroxylysine



数据库引用编号

48 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Dang Dang Wang, Guang Fu Tang, Yuan Yuan Li, Jun Jian Yu, Xin Jian Lei, Yang Chun Cao, Jun Hu Yao. Differences in serum metabolome profile explain individual variation in growth performance of young goats. Journal of proteomics. 2023 Jul; 288(?):104982. doi: 10.1016/j.jprot.2023.104982. [PMID: 37532014]
  • Shangqing Li, Guorong Lyu, Shaohui Li, Hainan Yang, Yiru Yang. Metabolic characterization of amniotic fluid of fetuses with isolated choroid plexus cyst. Journal of perinatal medicine. 2022 Oct; 50(8):1100-1106. doi: 10.1515/jpm-2022-0028. [PMID: 35607760]
  • Nina Patel, Philippa Mills, James Davison, Maureen Cleary, Paul Gissen, Blerida Banushi, Ivan Doykov, Megan Dorman, Kevin Mills, Wendy E Heywood. Free urinary glycosylated hydroxylysine as an indicator of altered collagen degradation in the mucopolysaccharidoses. Journal of inherited metabolic disease. 2020 03; 43(2):309-317. doi: 10.1002/jimd.12166. [PMID: 31452203]
  • Michael Behringer, Johannes Caspar Konrad Montag, Yvonne Kilian, Phil Heaton, Joachim Mester. Polyamines, myosin heavy chains, and collagen specific amino acids after a repeated bout of eccentric exercise. Research in sports medicine (Print). 2016 Jul; 24(3):287-97. doi: 10.1080/15438627.2016.1202830. [PMID: 27379471]
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  • Miquel Rojas-Cherto, Julio E Peironcely, Piotr T Kasper, Justin J J van der Hooft, Ric C H de Vos, Rob Vreeken, Thomas Hankemeier, Theo Reijmers. Metabolite identification using automated comparison of high-resolution multistage mass spectral trees. Analytical chemistry. 2012 Jul; 84(13):5524-34. doi: 10.1021/ac2034216. [PMID: 22612383]
  • Oliver Fricke, Christof Land, Ralf Beccard, Oliver Semler, Angelika Stabrey, Eckhard Schoenau. The relationship between body composition and the urinary excretion of deoxypyridinoline and galactosyl-hydroxylysine in children and adolescents. Journal of bone and mineral metabolism. 2009; 27(6):689-97. doi: 10.1007/s00774-009-0083-5. [PMID: 19526303]
  • Stephane Walrand, Eleni Chiotelli, Florence Noirt, Sandrine Mwewa, Taous Lassel. Consumption of a functional fermented milk containing collagen hydrolysate improves the concentration of collagen-specific amino acids in plasma. Journal of agricultural and food chemistry. 2008 Sep; 56(17):7790-5. doi: 10.1021/jf800691f. [PMID: 18707117]
  • Trifon Tofas, Athanasios Z Jamurtas, Ioannis Fatouros, Michalis G Nikolaidis, Yiannis Koutedakis, Efstathios A Sinouris, Nickoletta Papageorgakopoulou, Dimitrios A Theocharis. Plyometric exercise increases serum indices of muscle damage and collagen breakdown. Journal of strength and conditioning research. 2008 Mar; 22(2):490-6. doi: 10.1519/jsc.0b013e31816605a0. [PMID: 18550965]
  • Antti M Salo, Laura Sipilä, Raija Sormunen, Heli Ruotsalainen, Seppo Vainio, Raili Myllylä. The lysyl hydroxylase isoforms are widely expressed during mouse embryogenesis, but obtain tissue- and cell-specific patterns in the adult. Matrix biology : journal of the International Society for Matrix Biology. 2006 Oct; 25(8):475-83. doi: 10.1016/j.matbio.2006.08.260. [PMID: 16996725]
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  • P Collet, D Uebelhart, L Vico, L Moro, D Hartmann, M Roth, C Alexandre. Effects of 1- and 6-month spaceflight on bone mass and biochemistry in two humans. Bone. 1997 Jun; 20(6):547-51. doi: 10.1016/s8756-3282(97)00052-5. [PMID: 9177869]
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  • A Pecile, C Netti, V Sibilia, I Villa, G Calori, R Tenni, M Coluzzi, G L Moro, A Rubinacci. Comparison between urinary pyridinium cross-links and hydroxylysine glycosides in monitoring the effects of ovariectomy and 17 beta-estradiol replacement in aged rats. The Journal of endocrinology. 1996 Sep; 150(3):383-90. doi: 10.1677/joe.0.1500383. [PMID: 8882157]
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  • R Marabini, P Sirtori, R Chionna, L Barzizza, A Rubinacci. Galactosylhydroxylysine and pyridinium cross links in monitoring the bone response to hormone replacement therapy. Journal of endocrinological investigation. 1996 Mar; 19(3):154-8. doi: 10.1007/bf03349858. [PMID: 8743280]
  • P Bettica, A K Taylor, J Talbot, L Moro, R Talamini, D J Baylink. Clinical performances of galactosyl hydroxylysine, pyridinoline, and deoxypyridinoline in postmenopausal osteoporosis. The Journal of clinical endocrinology and metabolism. 1996 Feb; 81(2):542-6. doi: 10.1210/jcem.81.2.8636265. [PMID: 8636265]
  • M Romanello, K Noris Suarez, P Bettica, L Moro. Detection of pyridinium cross-links in human bile. Calcified tissue international. 1995 Dec; 57(6):415-8. doi: 10.1007/bf00301942. [PMID: 8581871]
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  • M Michalsky, J J Stepan, H Wilczek, J Formankova, L Moro. Galactosyl hydroxylysine in assessment of Paget's bone disease. Clinica chimica acta; international journal of clinical chemistry. 1995 Jan; 234(1-2):101-8. doi: 10.1016/0009-8981(94)05981-w. [PMID: 7758208]
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  • P Bettica, D J Baylink, L Moro. Galactosyl hydroxylysine and deoxypyridinoline: a methodological comparison. European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies. 1993 Jul; 31(7):459-65. doi: 10.1515/cclm.1993.31.7.459. [PMID: 8399787]
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