Bilobol (BioDeep_00000393887)

Main id: BioDeep_00000002758

 

natural product


代谢物信息卡片


5-[(8Z)-Pentadec-8-en-1-yl]benzene-1,3-diol

化学式: C21H34O2 (318.2559)
中文名称: 银杏酚
谱图信息: 最多检出来源 Homo sapiens(lipidomics) 32.52%

分子结构信息

SMILES: C1(O)C=C(CCCCCCC/C=C\CCCCCC)C=C(O)C=1
InChI: InChI=1S/C21H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-16-20(22)18-21(23)17-19/h7-8,16-18,22-23H,2-6,9-15H2,1H3/b8-7-



数据库引用编号

33 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

81 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 BCL2, CASP3, CASP9, MSMP, MX1, MX2, PLCG1, PTGS2, RHOA, SGCB
Peripheral membrane protein 2 MX1, PTGS2
Endoplasmic reticulum membrane 4 BCL2, MX1, PTGS2, RHOA
Nucleus 6 BCL2, CASP3, CASP9, MX1, MX2, RHOA
cytosol 7 BCL2, CASP3, CASP9, MX1, MX2, PLCG1, RHOA
nucleoplasm 1 CASP3
Cell membrane 1 RHOA
Lipid-anchor 1 RHOA
Cytoplasmic side 1 RHOA
Cleavage furrow 1 RHOA
lamellipodium 2 PLCG1, RHOA
ruffle membrane 2 PLCG1, RHOA
cell cortex 1 RHOA
cell junction 1 RHOA
glutamatergic synapse 3 CASP3, PLCG1, RHOA
lysosomal membrane 1 GAA
neuronal cell body 1 CASP3
postsynapse 1 RHOA
sarcolemma 1 SGCB
Lysosome 1 GAA
endosome 1 RHOA
plasma membrane 4 GAA, PLCG1, RHOA, SGCB
Membrane 4 BCL2, GAA, MX1, MX2
caveola 1 PTGS2
extracellular exosome 2 GAA, RHOA
Lysosome membrane 1 GAA
endoplasmic reticulum 2 BCL2, PTGS2
extracellular space 1 MSMP
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 1 MX1
Schaffer collateral - CA1 synapse 1 PLCG1
mitochondrion 2 BCL2, CASP9
protein-containing complex 3 BCL2, CASP9, PTGS2
intracellular membrane-bounded organelle 1 GAA
Microsome membrane 1 PTGS2
postsynaptic density 1 CASP3
Secreted 2 GAA, MSMP
extracellular region 1 GAA
cytoplasmic side of plasma membrane 1 RHOA
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 2 BCL2, MX1
dendritic spine 1 RHOA
midbody 1 RHOA
cell-cell junction 1 PLCG1
Single-pass type II membrane protein 1 SGCB
vesicle 1 RHOA
Cell membrane, sarcolemma 1 SGCB
Cell projection, lamellipodium 2 PLCG1, RHOA
Cytoplasm, perinuclear region 1 MX1
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 SGCB
focal adhesion 1 RHOA
microtubule 2 MX1, MX2
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Cell projection, ruffle 1 PLCG1
ruffle 1 PLCG1
neuron projection 1 PTGS2
cell projection 1 PLCG1
cell periphery 1 RHOA
cytoskeleton 2 RHOA, SGCB
COP9 signalosome 1 PLCG1
Cytoplasm, cell cortex 1 RHOA
Nucleus, nuclear pore complex 1 MX2
nuclear pore 1 MX2
Cell projection, dendrite 1 RHOA
tertiary granule membrane 1 GAA
myelin sheath 1 BCL2
secretory granule membrane 1 RHOA
endoplasmic reticulum lumen 1 PTGS2
azurophil granule membrane 1 GAA
apoptosome 1 CASP9
[Isoform 2]: Cytoplasm 1 MX1
ficolin-1-rich granule membrane 2 GAA, RHOA
death-inducing signaling complex 1 CASP3
apical junction complex 1 RHOA
dystrophin-associated glycoprotein complex 1 SGCB
sarcoglycan complex 1 SGCB
autolysosome lumen 1 GAA
BAD-BCL-2 complex 1 BCL2
caspase complex 1 CASP9


文献列表

  • Isaac Duah Boateng. Ginkgols and bilobols in Ginkgo biloba L. A review of their extraction and bioactivities. Phytotherapy research : PTR. 2023 May; ?(?):. doi: 10.1002/ptr.7877. [PMID: 37190926]
  • Heidi Luise Schulte, João Paulo Barreto Sousa, Diego Sousa-Moura, Cesar Koppe Grisolia, Laila Salmen Espindola. Degradation evaluation and toxicity profile of bilobol, a promising eco-friendly larvicide. Chemosphere. 2021 Jan; 263(?):128323. doi: 10.1016/j.chemosphere.2020.128323. [PMID: 33297255]
  • É V Beĭer, A A Skorniakov, É B Arushanian. [Chronotropic properties of adaptogenic drugs]. Eksperimental'naia i klinicheskaia farmakologiia. 2014; 77(10):3-5. doi: ". [PMID: 25518519]
  • É V Beĭer, A A Khazhbiev, É B Arushanian. [The optimizing influence of melatonin on the behavioral activity of cognitive enhancers]. Eksperimental'naia i klinicheskaia farmakologiia. 2013; 76(10):3-5. doi: ". [PMID: 24400380]
  • Chun-Po Chang, Hsun-Shuo Chang, Chien-Fang Peng, Shiow-Ju Lee, Ih-Sheng Chen. Antitubercular resorcinol analogs and benzenoid C-glucoside from the roots of Ardisia cornudentata. Planta medica. 2011 Jan; 77(1):60-5. doi: 10.1055/s-0030-1250094. [PMID: 20607650]
  • Pengcheng Lin, Shuai Li, Sujuan Wang, Yongchun Yang, Jiangong Shi. A nitrogen-containing 3-alkyl-1,4-benzoquinone and a gomphilactone derivative from Embelia ribes. Journal of natural products. 2006 Nov; 69(11):1629-32. doi: 10.1021/np060284m. [PMID: 17125236]
  • G Baron-Ruppert, N P Luepke. Evidence for toxic effects of alkylphenols from Ginkgo biloba in the hen's egg test (HET). Phytomedicine : international journal of phytotherapy and phytopharmacology. 2001 Mar; 8(2):133-8. doi: 10.1078/0944-7113-00022. [PMID: 11315756]
  • E D Zarnowska, R Zarnowski, A Kozubek. Alkylresorcinols in fruit pulp and leaves of Ginkgo biloba L. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2000 Nov; 55(11-12):881-5. doi: 10.1515/znc-2000-11-1206. [PMID: 11204190]
  • J S Lee, Y S Cho, E J Park, J Kim, W K Oh, H S Lee, J S Ahn. Phospholipase Cgamma1 inhibitory principles from the sarcotestas of Ginkgo biloba. Journal of natural products. 1998 Jul; 61(7):867-71. doi: 10.1021/np970367q. [PMID: 9677265]