Tolazoline (BioDeep_00000003486)
Secondary id: BioDeep_00000016562, BioDeep_00000861505
human metabolite blood metabolite
代谢物信息卡片
Ciba vision brand OF tolazoline hydrochloride
化学式: C10H12N2 (160.1)
中文名称: 2-苄基咪唑啉
谱图信息:
最多检出来源 Mus musculus(blood) 32.4%
分子结构信息
SMILES: C(C1=NCCN1)C1=CC=CC=C1
InChI: InChI=1S/C10H12N2/c1-2-4-9(5-3-1)8-10-11-6-7-12-10/h1-5H,6-8H2,(H,11,12)
描述信息
A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn. [PubChem]
M - Musculo-skeletal system > M02 - Topical products for joint and muscular pain > M02A - Topical products for joint and muscular pain
C - Cardiovascular system > C04 - Peripheral vasodilators > C04A - Peripheral vasodilators > C04AB - Imidazoline derivatives
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
同义名列表
18 个代谢物同义名
Ciba vision brand OF tolazoline hydrochloride; Novartis brand OF tolazoline hydrochloride; 4,5-Dihydro-2-(phenylmethyl)-1H-imidazole; 2-benzyl-4,5-dihydro-1H-imidazole; Tolazoline Monohydrochloride; Tolazoline hydrochloride; 2-Benzyl-4,5-imidazoline; 2-Benzyl-2-imidazoline; 2-Benzylimidazoline; Tolazoline; Benzalolin; Priscoline; Pridazole; Tolazine; Divascol; Priscol; Tolazoline; Tolazoline
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:28502
- KEGG: C07147
- KEGGdrug: D08614
- PubChem: 5504
- HMDB: HMDB0014935
- Metlin: METLIN2867
- DrugBank: DB00797
- ChEMBL: CHEMBL770
- Wikipedia: Tolazoline
- MeSH: Tolazoline
- chemspider: 5303
- CAS: 59-98-3
- PMhub: MS000009750
- PubChem: 9356
- NIKKAJI: J4.796A
- KNApSAcK: 28502
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lisa L Wolfe, Travis Mays, Mark C Fisher, Michael W Miller. Tissue Residue Levels of the Tranquilizer Combination of Butorphanol, Azaperone, and Medetomidine, and the Antagonists, Naltrexone, Atipamezole, and Tolazoline, in Black Bears (Ursus americanus) Postimmobilization.
Journal of wildlife diseases.
2020 10; 56(4):933-936. doi:
10.7589/jwd-d-19-00012. [PMID: 32348204] - Lisa L Wolfe, Pauline Nol, Matthew P McCollum, Travis Mays, Morgan E Wehtje, William R Lance, Mark C Fisher, Michael W Miller. Tissue Residue Levels after Immobilization of Rocky Mountain Elk ( Cervus elaphus nelsoni) using a Combination of Nalbuphine, Medetomidine, and Azaperone Antagonized with Naltrexone, Atipamezole, and Tolazoline.
Journal of wildlife diseases.
2018 04; 54(2):362-365. doi:
10.7589/2017-06-132. [PMID: 29148888] - Heather K Knych, Scott D Stanley. Effects of three antagonists on selected pharmacodynamic effects of sublingually administered detomidine in the horse.
Veterinary anaesthesia and analgesia.
2014 Jan; 41(1):36-47. doi:
10.1111/vaa.12081. [PMID: 24134603] - Stephen G Carter, Zhen Zhu, Gyula Varadi, Aristidis Veves, Jim E Riviere. Vasomodulation influences on the transdermal delivery of Ibuprofen.
Journal of pharmaceutical sciences.
2013 Nov; 102(11):4072-8. doi:
10.1002/jps.23719. [PMID: 23996466] - H C Casbeer, H K Knych. Pharmacokinetics and pharmacodynamic effects of tolazoline following intravenous administration to horses.
Veterinary journal (London, England : 1997).
2013 Jun; 196(3):504-9. doi:
10.1016/j.tvjl.2012.12.006. [PMID: 23321455] - Daniel J Warner, Hongming Chen, Louis-David Cantin, J Gerry Kenna, Simone Stahl, Clare L Walker, Tobias Noeske. Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Drug metabolism and disposition: the biological fate of chemicals.
2012 Dec; 40(12):2332-41. doi:
10.1124/dmd.112.047068. [PMID: 22961681] - Yasuto Kido, Pär Matsson, Kathleen M Giacomini. Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.
Journal of medicinal chemistry.
2011 Jul; 54(13):4548-58. doi:
10.1021/jm2001629. [PMID: 21599003] - Heather A Hostetler, Lindsay R Syler, Lindy N Hall, Guan Zhu, Friedhelm Schroeder, Ann B Kier. A novel high-throughput screening assay for putative antidiabetic agents through PPARalpha interactions.
Journal of biomolecular screening.
2008 Oct; 13(9):855-61. doi:
10.1177/1087057108323127. [PMID: 18812576] - Hanno Huwer, J Winning, U Straub, H Isringhaus, G Kalweit. Clinically diagnosed nonocclusive mesenteric ischemia after cardiopulmonary bypass: retrospective study.
Vascular.
2004 Mar; 12(2):114-20. doi:
10.1258/rsmvasc.12.2.114. [PMID: 15248641] - R O Akomolafe, I O Adeoshun, A O Ayoka, A A Elujoba, E O Iwalewa. An in vitro study of the effects of Cassia podocarpa fruit on the intestinal motility of rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2004 Feb; 11(2-3):249-54. doi:
10.1078/0944-7113-00330. [PMID: 15070180] - K J Stafford, D J Mellor, S E Todd, R N Ward, C M McMeekan. The effect of different combinations of lignocaine, ketoprofen, xylazine and tolazoline on the acute cortisol response to dehorning in calves.
New Zealand veterinary journal.
2003 Oct; 51(5):219-26. doi:
10.1080/00480169.2003.36370. [PMID: 16032330] - Todd M Delehant, Joseph W Denhart, W Eugene Lloyd, J D Powell. Pharmacokinetics of xylazine, 2,6-dimethylaniline, and tolazoline in tissues from yearling cattle and milk from mature dairy cows after sedation with xylazine hydrochloride and reversal with tolazoline hydrochloride.
Veterinary therapeutics : research in applied veterinary medicine.
2003; 4(2):128-34. doi:
NULL. [PMID: 14506588] - Pracha Nuntnarumit, Sheldon B Korones, Wenjian Yang, Henrietta S Bada. Efficacy and safety of tolazoline for treatment of severe hypoxemia in extremely preterm infants.
Pediatrics.
2002 May; 109(5):852-6. doi:
10.1542/peds.109.5.852. [PMID: 11986446] - J P Guignard. [Aggression to the immature kidney].
La Pediatria medica e chirurgica : Medical and surgical pediatrics.
2002 Mar; 24(2):105-10. doi:
. [PMID: 11987507] - T Hussein, T Clarke, H A Girim, T Matthews. Questionnaire on practices and priorities in neonatal care in Ireland.
Irish medical journal.
2001 Mar; 94(3):74-6, 78. doi:
NULL. [PMID: 11354687] - G Paret, O Eyal, H Mayan, E Gilad, R Ben-Abraham, D Ezra, Z Barzilay. Endotracheal tolazoline: pharmacokinetics and pharmacodynamics in dogs.
Acta paediatrica (Oslo, Norway : 1992).
1999 Sep; 88(9):1020-3. doi:
10.1080/08035259950168559. [PMID: 10519347] - G Paret, O Eyal, H Mayan, R Ben-Abraham, A Vardi, Y Manisterski, Z Barzilay, D Ezra. Pharmacokinetics of endobronchial tolazoline administration in dogs.
American journal of perinatology.
1999; 16(1):1-6. doi:
10.1055/s-2007-993827. [PMID: 10362074] - A Hercegová, J Sádecká, J Polonský. Isotachophoretic determination of bisoprolol, clonidine, disopyramide and tolazoline in human fluids.
Acta poloniae pharmaceutica.
1998 May; 55(3):167-71. doi:
NULL. [PMID: 9735699] - P J Havel, C Valverde. Autonomic mediation of glucagon secretion during insulin-induced hypoglycemia in rhesus monkeys.
Diabetes.
1996 Jul; 45(7):960-6. doi:
10.2337/diab.45.7.960. [PMID: 8666149] - J P Guignard. Effect of drugs on the immature kidney.
Advances in nephrology from the Necker Hospital.
1993; 22(?):193-211. doi:
NULL. [PMID: 8093987] - J C Jonas, T D Plant, J C Henquin. Imidazoline antagonists of alpha 2-adrenoceptors increase insulin release in vitro by inhibiting ATP-sensitive K+ channels in pancreatic beta-cells.
British journal of pharmacology.
1992 Sep; 107(1):8-14. doi:
10.1111/j.1476-5381.1992.tb14456.x. [PMID: 1358388] - J B Gouyon, J P Guignard. [Vasomotor kidney failure in the newborn infant. Physiopathology and treatment].
Archives francaises de pediatrie.
1989 Feb; 46(2):137-41. doi:
. [PMID: 2735793] - B V Venkataraman, A Hamada, G Shams, D D Miller, D R Feller, P N Patil. Paradoxical effects of isothiocyanate analog of tolazoline on rat aorta and human platelets.
Blood vessels.
1989; 26(6):335-46. doi:
10.1159/000158784. [PMID: 2577124] - A C Meeks, D G Sims. Treatment of renal failure in neonates.
Archives of disease in childhood.
1988 Nov; 63(11):1372-6. doi:
10.1136/adc.63.11.1372. [PMID: 3202646] - K R Murthy, A E Vakil. Elevation of plasma angiotensin levels in dogs by Indian red scorpion (Buthus tamulus) venom & its reversal by administration of insulin+tolazoline.
The Indian journal of medical research.
1988 Oct; 88(?):376-9. doi:
. [PMID: 3066753] - J P Guignard, J B Gouyon. Adverse effects of drugs on the immature kidney.
Biology of the neonate.
1988; 53(4):243-52. doi:
10.1159/000242797. [PMID: 2901276] - I Zebrowska-Lupina, G Szurska, B Klenk-Majewska. Involvement of alpha 2-adrenoceptors in the activation of kininogenesis by clonidine.
Polish journal of pharmacology and pharmacy.
1987 May; 39(3):267-72. doi:
. [PMID: 2830605] - M Duarte-Silva, S Naujoks, J P Guignard. Renal effects of tolazoline in newborn and adult rabbits.
Developmental pharmacology and therapeutics.
1987; 10(4):301-6. doi:
10.1159/000457756. [PMID: 3608753] - P Monin, C Dubruc, P Vert, P L Morselli. Treatment of persistent fetal circulation syndrome of the newborn. Comparison of different doses of tolazoline.
European journal of clinical pharmacology.
1987; 31(5):569-73. doi:
10.1007/bf00606632. [PMID: 3104058] - L M Todesco, J J Thoma, R D Barth, N J Myers, R White, R M Ward. Quantitative determination of tolazoline in human serum by high performance liquid chromatography.
Therapeutic drug monitoring.
1987; 9(1):78-84. doi:
10.1097/00007691-198703000-00014. [PMID: 3576663] - R M Ward, C H Daniel, J W Kendig, M A Wood. Oliguria and tolazoline pharmacokinetics in the newborn.
Pediatrics.
1986 Mar; 77(3):307-15. doi:
NULL. [PMID: 3951911] - E G John, R Bhat, F K Assadi, D Vidyasagar, L Fornell. Effect of tolazoline on renal function in newborn puppies.
Developmental pharmacology and therapeutics.
1986; 9(6):402-11. doi:
10.1159/000457264. [PMID: 3816493] - M J Cwik, G P Chiu, J H Fischer, E Chow-Tung, B L Currie. Quantitative determination of tolazoline in serum and urine.
Journal of chromatography.
1985 Feb; 338(1):123-30. doi:
10.1016/0378-4347(85)80076-1. [PMID: 4019639] - C F Ward. Congenital diaphragmatic hernia: association between pulmonary vascular resistance and plasma thromboxane concentrations.
Archives of disease in childhood.
1984 Nov; 59(11):1108. doi:
10.1136/adc.59.11.1108. [PMID: 6508348] - R Safirstein, P Miller, J B Guttenplan. Uptake and metabolism of cisplatin by rat kidney.
Kidney international.
1984 May; 25(5):753-8. doi:
10.1038/ki.1984.86. [PMID: 6540826] - G G Sandor, A J Macnab, F A Akesode, V J Ebelt, M R Pendray, W Y Ling, M W Patterson, M A Tipple. Clinical and echocardiographic evidence suggesting afterload reduction as a mechanism of action of tolazoline in neonatal hypoxemia.
Pediatric cardiology.
1984 Apr; 5(2):93-9. doi:
10.1007/bf02424957. [PMID: 6473128] - W D Ford, M J James, J A Walsh. Congenital diaphragmatic hernia: association between pulmonary vascular resistance and plasma thromboxane concentrations.
Archives of disease in childhood.
1984 Feb; 59(2):143-6. doi:
10.1136/adc.59.2.143. [PMID: 6546658] - R M Ward, C H Daniel, S R Willes, K J Gallaher. Tolazoline pharmacokinetics in lambs.
Pediatric pharmacology (New York, N.Y.).
1984; 4(2):101-7. doi:
NULL. [PMID: 6483501] - J P Guignard. [Renal disorders in the newborn infant].
La Pediatria medica e chirurgica : Medical and surgical pediatrics.
1984 Jan; 6(1):45-50. doi:
. [PMID: 6397726] - H Huland, D Gonnermann, H P Leichtweiss, R Dietrich-Hennings. Reversibility of preglomerular active vasoconstriction in the first weeks after complete unilateral ureteral obstruction by inhibition of prostaglandin synthesis.
The Journal of urology.
1983 Oct; 130(4):820-4. doi:
10.1016/s0022-5347(17)51473-1. [PMID: 6887428] - J W Flacke, W E Flacke, B C Bloor, S Olewine. Effects of fentanyl, naloxone, and clonidine on hemodynamics and plasma catecholamine levels in dogs.
Anesthesia and analgesia.
1983 Mar; 62(3):305-13. doi:
NULL. [PMID: 6829930] - T Tulassay, J Kiszel, I Seri, T Machay, P Sembery, J Varga. [The effect of tolazoline on kidney function in sick newborn infants].
Orvosi hetilap.
1982 Dec; 123(51):3133-5. doi:
NULL. [PMID: 6891768] - R M Ward, M J Cooper, B L Mirkin. Determination of tolazoline in plasma by gas chromatography-mass spectrometry.
Journal of chromatography.
1982 Sep; 231(2):445-50. doi:
10.1016/s0378-4347(00)81870-8. [PMID: 7130322] - V Rovei, G Remones, J P Thenot, P L Morselli. Determination of tolazoline in plasma by high-performance liquid chromatography.
Journal of chromatography.
1982 Aug; 231(1):210-5. doi:
10.1016/s0378-4347(00)80529-0. [PMID: 7119061] - J P Guignard. Drugs and the neonatal kidney.
Developmental pharmacology and therapeutics.
1982; 4 Suppl(?):19-27. doi:
10.1159/000457355. [PMID: 6751726] - Z Q Chen. [A new combined therapy of intra-arterial drug injection and oral traditional Chinese medicines in treatment of thromboangiitis obliterans (author's transl)].
Zhonghua wai ke za zhi [Chinese journal of surgery].
1981 Sep; 19(9):558-60. doi:
". [PMID: 7338116] - T D McKinney, P Myers, K V Speeg. Cimetidine secretion by rabbit renal tubules in vitro.
The American journal of physiology.
1981 Jul; 241(1):F69-76. doi:
10.1152/ajprenal.1981.241.1.f69. [PMID: 7246776] - W Oh. Renal functions and clinical disorders in the neonate.
Clinics in perinatology.
1981 Jun; 8(2):215-23. doi:
10.1016/s0095-5108(18)31075-3. [PMID: 7273583] - R S Trompeter, C Chantler, G B Haycock. Tolazoline and acute renal failure in the newborn.
Lancet (London, England).
1981 May; 1(8231):1219. doi:
10.1016/s0140-6736(81)92393-x. [PMID: 6112562] - B Sutphin, R T Schweizer, S A Bartus. Reversal of renal vasospasm by venous perfusion.
Transplantation proceedings.
1981 Mar; 13(1 Pt 2):702-6. doi:
NULL. [PMID: 7022936] - A Veselková, V Brodan. [Elimination of urinary catecholamines and their metabolites after administration of atropine and of alpha and beta sympatholytics in healthy volunteers (author's transl)].
Casopis lekaru ceskych.
1981; 120(50):1533-6. doi:
NULL. [PMID: 6120042] - T Yamato, M Yamagishi, M Mizuki, M Morita, S Kitamura, Y Ishihara. [The treatment of asthmatic patients using an alpha-adrenoreceptor blocking agents--changes of various pulmonary function tests and plasma cyclic AMP levels (author's transl)].
Nihon Kyobu Shikkan Gakkai zasshi.
1981 Jan; 19(1):18-24. doi:
NULL. [PMID: 6262546] - S Naujoks, J P Guignard. Renal effects of tolazoline in rabbits.
Lancet (London, England).
1979 Nov; 2(8151):1075-6. doi:
10.1016/s0140-6736(79)92472-3. [PMID: 91812] - A Orts, J L Martí, J Marco, I Baltar, J Castejón. Effects of adrenergic blockers on platelet aggregation.
Revista espanola de fisiologia.
1979 Sep; 35(3):269-72. doi:
. [PMID: 41294] - D Jezová-Repceková, I Klimes, J Jurcovicová, M Vigas. Effect of adrenergic receptor blockade on cortisol and GH response to insulin-induced hypoglycemia in man.
International journal of clinical pharmacology and biopharmacy.
1979 Feb; 17(2):64-7. doi:
. [PMID: 422303] - V P Chuang, A M Fried. High-dose renal pharmacoangiography in the assessment of hypovascular renal neoplasms.
AJR. American journal of roentgenology.
1978 Nov; 131(5):807-11. doi:
10.2214/ajr.131.5.807. [PMID: 101032] - D Friedburg, B Meissner. Fluorescein angiography of the corneal limbus--drug effects on capillary blood flow.
Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology.
1978 Aug; 207(3):213-9. doi:
10.1007/bf00411055. [PMID: 309738] - L C Waite, M D Lineberry. Hypocalcemic effect of phentolamine.
Research communications in chemical pathology and pharmacology.
1978 Mar; 19(3):403-16. doi:
. [PMID: 653098] - T Brecht, J P Hedde, R Felix, G Trübestein, C Winkler. [The effect of drugs on the perfusion distribution of the terminal vascular bed in upper extremity arterial circulatory disorders. Scintigraphic studies including a double radionuclide procedure].
Verhandlungen der Deutschen Gesellschaft fur Innere Medizin.
1977 Apr; 83(?):1753-5. doi:
NULL. [PMID: 25530] - R A Scherrer, S M Howard. Use of distribution coefficients in quantitative structure-activity relationships.
Journal of medicinal chemistry.
1977 Jan; 20(1):53-8. doi:
10.1021/jm00211a010. [PMID: 13215] - L Ekelund, J Göthlin, N Jonsson, H O Sjögren. Pharmacoangiography in experimental tumours. Evaluation of vasoactive drugs.
Acta radiologica: diagnosis.
1976 May; 17(3):329-42. doi:
10.1177/028418517601700310. [PMID: 937051] - W A Pettinger. Drug therapy: clonidine, a new antihypertensive drug.
The New England journal of medicine.
1975 Dec; 293(23):1179-80. doi:
10.1056/nejm197512042932306. [PMID: 1102978] - P Castner, H W Goldman, D Lehr. Participation of cholinergic circuits in renin induced drinking.
Life sciences.
1975 Feb; 16(4):573-83. doi:
NULL. [PMID: 1123960] - J L Falk, M Tang, R W Bryant. Dipsogenic action of diazoxide: a pharmacologic analysis.
The Journal of pharmacology and experimental therapeutics.
1974 Jul; 190(1):154-64. doi:
NULL. [PMID: 4152587] - J Bruna. [Pharmacodynamic lymphography (author's transl)].
Rontgen-Blatter; Zeitschrift fur Rontgen-Technik und medizinisch-wissenschaftliche Photographie.
1974 May; 27(5):262-6. doi:
NULL. [PMID: 4838870] - M S Sohel, D M Brahamankar, C T Chopde, A K Dorle. Influence of adrenergic blockers and antilipemic agents on pharmacodynamic actions of morphine in carbon tetrachloride-treated rats.
Toxicology and applied pharmacology.
1974 Mar; 27(3):477-83. doi:
10.1016/0041-008x(74)90026-x. [PMID: 4852425] - F J Macri, S J Cevario. The induction of aqueous humor formation by the use of Ach+eserine.
Investigative ophthalmology.
1973 Dec; 12(12):910-6. doi:
NULL. [PMID: 4768595] - N Wagner, T J Degnan. Hyperaggregation effect in idiopathic thrombocytopenia and multiple transfused patients.
Journal of clinical pathology.
1973 Sep; 26(9):697-9. doi:
10.1136/jcp.26.9.697. [PMID: 4752412] - K M Bron, J W Stilley, A P Shapiro. Renal arteriography enhanced by tolazoline. Value in the diagnosis of polyarteritis nodosa complicated by perinephric hematoma.
Radiology.
1971 May; 99(2):295-301. doi:
10.1148/99.2.295. [PMID: 4396521] - W J Dempster. The nature of experimental second-set kidney transplant rejection. 2. The mimicking of the haemodynamic upset by pharmacological and other means.
British journal of experimental pathology.
1971 Apr; 52(2):172-85. doi:
NULL. [PMID: 4325831] - D Lehr, M Krukowski, R Chau. Acute myocardial injury produced by sympathomimetic amines.
Israel journal of medical sciences.
1969 Jul; 5(4):519-24. doi:
NULL. [PMID: 5820469] - D Lehr. Tissue electrolyte alteration in disseminated myocardial necrosis.
Annals of the New York Academy of Sciences.
1969 Jan; 156(1):344-78. doi:
10.1111/j.1749-6632.1969.tb16739.x. [PMID: 5291140] - H Frisius, K H Beyer. [A severe quinine poisoning: clinic, toxicology and therapy].
Archiv fur Toxikologie.
1969; 24(2):201-13. doi:
NULL. [PMID: 5764884] - D Rehbinder, W Deckers. [Metabolic effects of Catapres].
Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie.
1968; 261(2):162-75. doi:
". [PMID: 4235048] - D Lehr, J Mallow, M Krukowski. Copious drinking and simultaneous inhibition of urine flow elicited by beta-adrenergic stimulation and contrary effect of alpha-adrenergic stimulation.
The Journal of pharmacology and experimental therapeutics.
1967 Oct; 158(1):150-63. doi:
NULL. [PMID: 6054075] - B R Rennick. Transport mechanisms for renal tubular excretion of creatinine in the chicken.
The American journal of physiology.
1967 May; 212(5):1131-4. doi:
10.1152/ajplegacy.1967.212.5.1131. [PMID: 6023870] - H G Götz. [Obstetric drugs. 16].
Pharmazeutische Praxis.
1967; 9(?):265-70. doi:
". [PMID: 4893528] - A FARAH, M FRAZER. STUDIES ON THE RATE OF RUNOUT OF N-METHYLNICOTIAMIDE FROM DOG RENAL SLICES.
The Journal of pharmacology and experimental therapeutics.
1964 Aug; 145(?):187-93. doi:
NULL. [PMID: 14214416] - K HASHIMOTO, S KUMAKURA, N TAIRA. VASCULAR REFLEX RESPONSES INDUCED BY AN INTRAARTERIAL INJECTION OF AZAAZEPINOPHENOTHIAZINE, ANDROMEDOTOXIN, VERATRIDINE, BRADYKININ AND KALLIKREIN AND BLOCKING ACTION OF SODIUM SALICYLATE.
The Japanese journal of physiology.
1964 Jun; 14(?):299-308. doi:
10.2170/jjphysiol.14.299. [PMID: 14187438] - C R BOSHART, T C SMITH, L WILL, A PIRRE, J PERRINE, I RINGLER. ACTION OF PHENTOLAMINE ON RAT ADIPOSE TISSUE.
The Journal of pharmacology and experimental therapeutics.
1964 Feb; 143(?):221-9. doi:
". [PMID: 14163996] - E SANNER. STUDIES ON THE EXCRETION MECHANISM OF SEROTONIN (5-HYDROXYTRYPTAMINE) IN THE CHICKEN KIDNEY.
Acta physiologica Scandinavica.
1963 Aug; 58(?):330-41. doi:
10.1111/j.1748-1716.1963.tb02655.x. [PMID: 14085185] - E SANNER. TUBULAR EXCRETION OF DOPAMINE (3-HYDROXYTYRAMINE) BY THE CHICKEN KIDNEY.
Acta pharmacologica et toxicologica.
1963; 20(?):375-84. doi:
10.1111/j.1600-0773.1964.tb01760.x. [PMID: 14162822] - A KANDEL, R E GREEN, R L VOLLE, L PETERS. Observations concerning the renal tubular transport of priscoline (tolazoline).
The Journal of pharmacology and experimental therapeutics.
1958 Mar; 122(3):327-34. doi:
NULL. [PMID: 13539758] - T D ULLMANN, J A STEIN. The effect of benzazoline (2-benzyl-4,5-imidazoline hydrochloride) (priscoline) on renal function in hypertensive man.
Angiology.
1955 Feb; 6(1):37-46. doi:
10.1177/000331975500600104. [PMID: 14350294] - J W McCUBBIN, I H PAGE. Modification of the hypotensive action of 1-hydrazinophthalazine (apresoline) by priscoline, hexamethonium and section of the carotid sinus and aortic buffer nerves in normal and renal hypertensive dogs.
The American journal of the medical sciences.
1953 Dec; 226(6):632-5. doi:
10.1097/00000441-195312000-00005. [PMID: 13104415] - J ORLOFF, L ARONOW, R W BERLINER. The transport of priscoline by the renal tubules.
The Journal of pharmacology and experimental therapeutics.
1953 Oct; 109(2):214-7. doi:
NULL. [PMID: 13097354] - R G JANES, L S BOEKE. Influence of niacin and priscoline on ketonuria, liver glycogen and liver lipid.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1952 Aug; 80(4):591-4. doi:
10.3181/00379727-80-19702. [PMID: 12983353] - W G YOUNG, J S HARRIS, W C SEALY, M J WARE. Production of neurogenic afferent renal vasoconstriction in humans and dogs by 2-benzyl-4,5-imidazoline HCl (priscoline).
Journal of applied physiology.
1950 Aug; 3(2):77-83. doi:
10.1152/jappl.1950.3.2.77. [PMID: 14774324]
