Amikacin (BioDeep_00000003438)

 

Secondary id: BioDeep_00000408799

human metabolite blood metabolite Chemicals and Drugs Antibiotics


代谢物信息卡片


(2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide

化学式: C22H43N5O13 (585.2857228)
中文名称: 丁胺卡那霉素, 阿米卡星
谱图信息: 最多检出来源 Homo sapiens(blood) 66.67%

分子结构信息

SMILES: C(CN)[C@@H](C(=O)N[C@@H]1C[C@@H]([C@H]([C@@H]([C@H]1O[C@@H]1[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)N)O)O)O[C@@H]1[C@@H]([C@H]([C@@H]([C@@H](CN)O1)O)O)O)N)O
InChI: InChI=1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+/m0/s1

描述信息

Amikacin is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A. Similar to other aminoglycosides, amikacin disrupts bacterial protein synthesis by binding to the 30S ribosome of susceptible organisms. Binding interferes with mRNA binding and tRNA acceptor sites leading to the production of non-functional or toxic peptides. Other mechanisms not fully understood may confer the bactericidal effects of amikacin. Amikacin is also nephrotoxic and ototoxic.
D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06A - Antibiotics for topical use
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01G - Aminoglycoside antibacterials
S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AA - Antibiotics
C784 - Protein Synthesis Inhibitor > C2363 - Aminoglycoside Antibiotic
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C254 - Anti-Infective Agent > C258 - Antibiotic
KEIO_ID A239

同义名列表

60 个代谢物同义名

(2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide; O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine; O-3-Amino-3-deoxy-a-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-a-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine; O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-α-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine; 1-N-(L(-)-gamma-Amino-alpha-hydroxybutyryl)kanamycin a; 1-N-(L(-)-g-Amino-a-hydroxybutyryl)kanamycin a; Bristol myers squibb brand OF amikacin sulfate; 1-N-(L(-)-Γ-amino-α-hydroxybutyryl)kanamycin a; Bristol-myers squibb brand OF amikacin sulfate; Mead johnson brand OF amikacin sulfate; Cryopharma brand OF amikacin sulfate; Apothecon brand OF amikacin sulfate; Grossmann brand OF amikacin sulfate; Collins brand OF amikacin sulfate; Fustery brand OF amikacin sulfate; Medical brand OF amikacin sulfate; Norman brand OF amikacin sulfate; Lemery brand OF amikacin sulfate; Galen brand OF amikacin sulfate; Sons brand OF amikacin sulfate; Pisa brand OF amikacin sulfate; Rovi brand OF amikacin sulfate; Amikacin dihydrate; Medical, amikacina; Sulfate, amikacin; Normon, amikacina; Amikacina medical; Amikacin sulfate; Amikacina normon; ANTIBIOTIC BB-K8; Amikacin base; Amiglyde-V; Amikacinum; Amikayect; Amikasons; Amikacine; Amikacina; Yectamid; Amikalem; Amikavet; Amikafur; Amikacin; Amicacin; Briclin; Amiklin; Kanbine; Gamikal; Amukin; Biclin; Biklin; BB-K 8; BB K 8; Amikin; BBK 8; BB-K8; BB K8; A.M.K; Oprad; BBK8; AMK



数据库引用编号

24 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ruiyun Zhang, Xiao Huang, Qiaoli Wu, Shirun Chu, Xue Bai, Yuanyuan Zhou, Jing You, Chen Yang, Huan Tan. Multifunctional gelatin nanoparticle stabilized-Pickering emulsion hydrogel based on dextran and amikacin with controlled drug release and enhanced antibacterial capability for promoting infected wound healing. International journal of biological macromolecules. 2024 Mar; 262(Pt 2):130172. doi: 10.1016/j.ijbiomac.2024.130172. [PMID: 38360230]
  • Yuting Zhao, Peiyong Guo, Dan Li, Mengjie Liu, Junhao Zhang, Kai Yuan, Hua Zheng, Liang Liu. Preparation and evaluation of oxidized-dextran based on antibacterial hydrogel for synergistic photodynamic therapy. International journal of biological macromolecules. 2023 Dec; 253(Pt 8):127648. doi: 10.1016/j.ijbiomac.2023.127648. [PMID: 37890748]
  • Tong Xie, Jing Lin, Degui Lin, Di Zhang, Xudong Xu, Nailiang Zhu, Jiahao Lin. In vitro and in vivo antibacterial studies of volatile oil from Atractylodis Rhizoma against Staphylococcus pseudintermedius and multidrug resistant Staphylococcus pseudintermedius strains from canine pyoderma. Journal of ethnopharmacology. 2023 Oct; 319(Pt 3):117326. doi: 10.1016/j.jep.2023.117326. [PMID: 37879504]
  • Ronald Rodriguez, Nick Campbell-Kruger, Jesus Gonzalez Camba, John Berude, Rachel Fetterman, Sarah Stanley. MarR-Dependent Transcriptional Regulation of mmpSL5 Induces Ethionamide Resistance in Mycobacterium abscessus. Antimicrobial agents and chemotherapy. 2023 Mar; ?(?):e0135022. doi: 10.1128/aac.01350-22. [PMID: 36988462]
  • Claudia Vairo, Maria Villar Vidal, Rosa Maria Hernandez, Manoli Igartua, Silvia Villullas. Colistin- and Amikacin-loaded lipid-based drug delivery systems for resistant gram-negative lung and wound bacterial infections. International journal of pharmaceutics. 2023 Feb; ?(?):122739. doi: 10.1016/j.ijpharm.2023.122739. [PMID: 36801363]
  • Kaiyu Cui, Weifeng Yang, Zhiyuan Liu, Guijian Liu, Dongying Li, Yanan Sun, Gaiying He, Shuhua Ma, Yu Cao, Xuefan Jiang, Sylvie Chevalier, Pierre Cornelis, Qing Wei, Yi Wang. Chenodeoxycholic Acid-Amikacin Combination Enhances Eradication of Staphylococcus aureus. Microbiology spectrum. 2023 Feb; 11(1):e0243022. doi: 10.1128/spectrum.02430-22. [PMID: 36625660]
  • Sebile Azırak. Prevention of nephrotoxicity induced by amikacin: The role of misoprostol, A prostaglandin E1 analogue. Prostaglandins & other lipid mediators. 2023 Feb; 164(?):106682. doi: 10.1016/j.prostaglandins.2022.106682. [PMID: 36349661]
  • Laijun Yan, Haiya Ge, Yan Zhang, Nan Li. Epidemiology of pathogens and antimicrobial resistance of nosocomial urinary tract infections in patients with spinal cord injuries in China: A systematic review and meta-analysis. The journal of spinal cord medicine. 2023 Jan; ?(?):1-17. doi: 10.1080/10790268.2022.2129154. [PMID: 36622339]
  • Sedat Bilgiç, Meltem Özgöçmen, Mehmet Kaya Ozer. Thymoquinone ameliorates amikacin induced oxidative damage in rat brain tissue. Biotechnic & histochemistry : official publication of the Biological Stain Commission. 2023 Jan; 98(1):38-45. doi: 10.1080/10520295.2022.2087905. [PMID: 35811486]
  • Peiyao Jia, Xinmiao Jia, Ying Zhu, Xiaoyu Liu, Wei Yu, Rui Li, Xue Li, Mei Kang, Yingchun Xu, Qiwen Yang. Emergence of a Novel NDM-5-Producing Sequence Type 4523 Klebsiella pneumoniae Strain Causing Bloodstream Infection in China. Microbiology spectrum. 2022 10; 10(5):e0084222. doi: 10.1128/spectrum.00842-22. [PMID: 35993711]
  • Mohamad Rahmati, Ebrahim Babapoor, Mehrouz Dezfulian. Amikacin-loaded niosome nanoparticles improve amikacin activity against antibiotic-resistant Klebsiella pneumoniae strains. World journal of microbiology & biotechnology. 2022 Oct; 38(12):230. doi: 10.1007/s11274-022-03405-2. [PMID: 36184645]
  • Abdulghani Ashraf Halabi, Bassma H Elwakil, Mohamed Hagar, Zakia A Olama. Date Fruit (Phoenix dactylifera L.) Cultivar Extracts: Nanoparticle Synthesis, Antimicrobial and Antioxidant Activities. Molecules (Basel, Switzerland). 2022 Aug; 27(16):. doi: 10.3390/molecules27165165. [PMID: 36014407]
  • Xiaocui Wu, Guangkun Tan, Jinghui Yang, Yinjuan Guo, Chengchen Huang, Wei Sha, Fangyou Yu. Prediction of Mycobacterium tuberculosis drug resistance by nucleotide MALDI-TOF-MS. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2022 Aug; 121(?):47-54. doi: 10.1016/j.ijid.2022.04.061. [PMID: 35523300]
  • Taylor Abbey, Alesia Vialichka, Michele Jurkovic, Mark Biagi, Eric Wenzler. Activity of Omadacycline Alone and in Combination against Carbapenem-Nonsusceptible Acinetobacter baumannii with Varying Minocycline Susceptibility. Microbiology spectrum. 2022 06; 10(3):e0054222. doi: 10.1128/spectrum.00542-22. [PMID: 35647655]
  • Silvia Martini, Francesca Vitali, Irene Capelli, Chiara Donadei, Emanuel Raschi, Valeria Aiello, Luigi Corvaglia, Fabrizio De Ponti, Elisabetta Poluzzi, Silvia Galletti. Impact of nephrotoxic drugs on urinary biomarkers of renal function in very preterm infants. Pediatric research. 2022 06; 91(7):1715-1722. doi: 10.1038/s41390-021-01905-9. [PMID: 34897282]
  • Shahbaz Ahmad, Farooq Ali, Sadaf Anwar Qureshi, Bibi Uzma, Qismat Shakeela, Muhammad Shehryar Sabir, Sajjad Ahmad, Ijazul Haq, Atia Rasheed, Shehzad Ahmed, Muhammad Farooq. The evaluation of antibiotic susceptibility pattern and associated risk factors of UTI in tertiary care hospital of Peshawar. Pakistan journal of pharmaceutical sciences. 2022 May; 35(3(Special)):897-903. doi: NULL. [PMID: 35791585]
  • Xiaocui Wu, Guangkun Tan, Wei Sha, Haican Liu, Jinghui Yang, Yinjuan Guo, Xin Shen, Zheyuan Wu, Hongbo Shen, Fangyou Yu. Use of Whole-Genome Sequencing to Predict Mycobacterium tuberculosis Complex Drug Resistance from Early Positive Liquid Cultures. Microbiology spectrum. 2022 04; 10(2):e0251621. doi: 10.1128/spectrum.02516-21. [PMID: 35311541]
  • Bita Shahrami, Aida Sefidani Forough, Seyedeh Sana Khezrnia, Farhad Najmeddin, Amir Ahmad Arabzadeh, Mohammad Reza Rouini, Atabak Najafi, Mojtaba Mojtahedzadeh. Relationship between amikacin pharmacokinetics and biological parameters associated with organ dysfunction: a case series study of critically ill patients with intra-abdominal sepsis. European journal of hospital pharmacy : science and practice. 2022 03; 29(e1):e72-e76. doi: 10.1136/ejhpharm-2021-003089. [PMID: 34764144]
  • Saeideh Ghaffari, Ali Mohammad Hadi, Farhad Najmeddin, Bita Shahrami, Mohammad-Reza Rouini, Atabak Najafi, Mojtaba Mojtahedzadeh. Evaluation of amikacin dosing schedule in critically ill elderly patients with different stages of renal dysfunction. European journal of hospital pharmacy : science and practice. 2022 03; 29(e1):e67-e71. doi: 10.1136/ejhpharm-2021-002986. [PMID: 34588225]
  • Lijie Xu, Xuefang Cheng, Guanhua Zhu, Juanni Hu, Qin Li, Guorong Fan. Therapeutic drug monitoring of amikacin: quantification in plasma by liquid chromatography-tandem mass spectrometry and work experience of clinical pharmacists. European journal of hospital pharmacy : science and practice. 2022 03; 29(e1):e77-e82. doi: 10.1136/ejhpharm-2021-003049. [PMID: 34789474]
  • Ali Mohebbi, Abolghasem Jouyban, Mir Ali Farajzadeh, Mohammad Reza Afshar Mogaddam, Mahboob Nemati. Development of an in-syringe gas-assisted density tunable solidification of floating organic droplet-based dispersive liquid phase microextraction method coupled with HPLC-MS/MS for monitoring amikacin in biological fluids. Journal of pharmaceutical and biomedical analysis. 2022 Feb; 210(?):114552. doi: 10.1016/j.jpba.2021.114552. [PMID: 34979495]
  • Chongmei Tian, Mengyu Xing, Yaping Zhao, Xueyu Fan, Yongfeng Bai, Liping Fu, Siwei Wang. Whole genome sequencing of OXA-232-producing wzi93-KL112-O1 carbapenem-resistant Klebsiella pneumoniae in human bloodstream infection co-harboring chromosomal ISEcp1-based bla CTX-M-15 and one rmpA2-associated virulence plasmid. Frontiers in cellular and infection microbiology. 2022; 12(?):984479. doi: 10.3389/fcimb.2022.984479. [PMID: 36250056]
  • Jessica M Gilbertie, Thomas P Schaer, Julie B Engiles, Gabriela S Seiler, Bennett L Deddens, Alicia G Schubert, Megan E Jacob, Darko Stefanovski, Gordon Ruthel, Noreen J Hickok, Devorah M Stowe, Alexa Frink, Lauren V Schnabel. A Platelet-Rich Plasma-Derived Biologic Clears Staphylococcus aureus Biofilms While Mitigating Cartilage Degeneration and Joint Inflammation in a Clinically Relevant Large Animal Infectious Arthritis Model. Frontiers in cellular and infection microbiology. 2022; 12(?):895022. doi: 10.3389/fcimb.2022.895022. [PMID: 35711655]
  • Zeinab Mahmoud Saeed, Monira Ismail Khattab, Nadia Esmat Khorshid, Amal Elsayed Salem. Ellagic acid and cilostazol ameliorate amikacin-induced nephrotoxicity in rats by downregulating oxidative stress, inflammation, and apoptosis. PloS one. 2022; 17(7):e0271591. doi: 10.1371/journal.pone.0271591. [PMID: 35849599]
  • Ibtisam H Al-Azawi, Mahasin S Al-Bidiri. DISTRIBUTION OF INTEGRON III AND PHYLOGENIC CLADE AMONG MDR UROPATHOGENIC E. COLI FROM PATIENT IN AL-DIWANIYAH CITY, IRAQ. Wiadomosci lekarskie (Warsaw, Poland : 1960). 2022; 75(5 pt 2):1254-1260. doi: 10.36740/wlek202205205. [PMID: 35758440]
  • Diógenes Rodrigues, Giulia Soska Baldissera, Douglas Mathos, Aline Sartori, Alexandre P Zavascki, Maria Helena Rigatto. Amikacin for the treatment of carbapenem-resistant Klebsiella pneumoniae infections: clinical efficacy and toxicity. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]. 2021 Dec; 52(4):1913-1919. doi: 10.1007/s42770-021-00551-x. [PMID: 34191252]
  • Katie D Mauro, Christine A Culler, Alessio Vigani. Emergency treatment with intermittent hemodialysis for amikacin overdose in a cat. Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001). 2021 Nov; 31(6):813-817. doi: 10.1111/vec.13134. [PMID: 34499808]
  • K Sridharan, M Al Jufairi, O Al Segai, E Al Ansari, H Hashem Ahmed, G Husain Shaban, Z Malalla, R Al Marzooq, A Al Madhoob, K Saeed Tabbara. Biomarkers in neonates receiving potential nephrotoxic drugs. European review for medical and pharmacological sciences. 2021 Nov; 25(22):7078-7088. doi: 10.26355/eurrev_202111_27260. [PMID: 34859872]
  • Silvia Corcione, Amedeo De Nicolò, Tommaso Lupia, Francesco Vladimiro Segala, Anna Pensa, Riccardo Corgiat Loia, Maria Rosa Romeo, Giovanni Di Perri, Maurizio Stella, Antonio D'Avolio, Francesco Giuseppe De Rosa. Observed concentrations of amikacin and gentamycin in the setting of burn patients with gram-negative bacterial infections: Preliminary data from a prospective study. Therapie. 2021 Sep; 76(5):409-414. doi: 10.1016/j.therap.2020.10.003. [PMID: 33257012]
  • Alvaro G Bonilla, Lisa Causeret, Albert Torrent-Crosa. Pharmacokinetics of ceftiofur in the metacarpophalangeal joint after standing intravenous regional limb perfusion in horses. The Canadian veterinary journal = La revue veterinaire canadienne. 2021 09; 62(9):975-981. doi: NULL. [PMID: 34475583]
  • Zhili Li, Walter Perkins, David Cipolla. Robustness of aerosol delivery of amikacin liposome inhalation suspension using the eFlow® Technology. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2021 Sep; 166(?):10-18. doi: 10.1016/j.ejpb.2021.05.021. [PMID: 34082122]
  • Sabrina De Winter, Reinier van Hest, Erwin Dreesen, Pieter Annaert, Joost Wauters, Wouter Meersseman, Nele Van den Eede, Stefanie Desmet, Sandra Verelst, Peter Vanbrabant, Willy Peetermans, Isabel Spriet. Quantification and Explanation of the Variability of First-Dose Amikacin Concentrations in Critically Ill Patients Admitted to the Emergency Department: A Population Pharmacokinetic Analysis. European journal of drug metabolism and pharmacokinetics. 2021 Sep; 46(5):653-663. doi: 10.1007/s13318-021-00698-w. [PMID: 34297338]
  • Neveen Madbouly, Ayman Azmy, Abeer Salama, Azza El-Amir. The nephroprotective properties of taurine-amikacin treatment in rats are mediated through HSP25 and TLR-4 regulation. The Journal of antibiotics. 2021 09; 74(9):580-592. doi: 10.1038/s41429-021-00441-2. [PMID: 34253885]
  • Hassan Al Mana, Sathyavathi Sundararaju, Nahla O Eltai, Sara H Al-Hadidi, Mohammad Rubayet Hasan, Patrick Tang, Andrés Pérez-López. Low-level amikacin resistance induced by AAC(6')-Ib and AAC(6')-Ib-cr in extended-spectrum β-lactamase (ESBL)-producing Enterobacterales isolated from urine in children. Journal of global antimicrobial resistance. 2021 09; 26(?):42-44. doi: 10.1016/j.jgar.2021.04.026. [PMID: 34029770]
  • Jean-Baptiste Woillard, Stéphane Bouchet, Michael Fayon, Pierre Marquet, Caroline Monchaud, Stéphanie Bui. A Population Pharmacokinetic Modeling Approach to Determine the Efficacy of Intravenous Amikacin in Children with Cystic Fibrosis. Therapeutic drug monitoring. 2021 08; 43(4):499-504. doi: 10.1097/ftd.0000000000000855. [PMID: 33346630]
  • Kajsa Gustafsson, Amos J Tatz, Roee Dahan, Malka Britzi, Stefan Soback, Wiessam Abu Ahmad, Hagar Prince, Gal Kelmer. The Concentration of Metronidazole in the Distal Interphalangeal Joint following Intravenous Regional Limb Perfusion via the Cephalic Vein in Standing Horses. Veterinary and comparative orthopaedics and traumatology : V.C.O.T. 2021 Jul; 34(4):287-293. doi: 10.1055/s-0041-1726083. [PMID: 33979876]
  • Rym Medjebeur Hanna, Michael Levy, Emmanuelle Bille, Carole Hennequin, Fabrice Lesage, Jérôme Naudin, Florence Moulin, Marie Blanquer, Agathe Béranger, Sylvain Renolleau, Mehdi Oualha, Mathieu Genuini. Assessment of the Effects of a High Amikacin Dose on Plasma Peak Concentration in Critically Ill Children. Paediatric drugs. 2021 Jul; 23(4):395-401. doi: 10.1007/s40272-021-00456-0. [PMID: 34142330]
  • Paula Chávez M, Aivlys Fernández H, Rubén Hernández M, Luis Delpiano M. [Impact of the vancomycin and amikacin therapeutic monitoring in the optimization of antimicrobial dose in pediatric patients]. Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia. 2021 Jun; 38(3):317-323. doi: 10.4067/s0716-10182021000300317. [PMID: 34479286]
  • Aida Dizdarević, Melani Marić, Iram Shahzadi, Nuri Ari Efiana, Barbara Matuszczak, Andreas Bernkop-Schnürch. Imine bond formation as a tool for incorporation of amikacin in self-emulsifying drug delivery systems (SEDDS). European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2021 May; 162(?):82-91. doi: 10.1016/j.ejpb.2021.03.001. [PMID: 33737147]
  • Ahmed Aljishi, Marwan Jabr Alwazzeh, Mar Kristjansson. Pneumonia due to Mycobacterium cosmeticum in a renal transplant recipient. BMJ case reports. 2021 Mar; 14(3):. doi: 10.1136/bcr-2020-234800. [PMID: 33653829]
  • Christopher M Rubino, Nikolas J Onufrak, Jakko van Ingen, David E Griffith, Sujata M Bhavnani, Dayton W Yuen, Kevin C Mange, Kevin L Winthrop. Population Pharmacokinetic Evaluation of Amikacin Liposome Inhalation Suspension in Patients with Treatment-Refractory Nontuberculous Mycobacterial Lung Disease. European journal of drug metabolism and pharmacokinetics. 2021 Mar; 46(2):277-287. doi: 10.1007/s13318-020-00669-7. [PMID: 33595792]
  • Ying Wang, Zhichao Du, Yongdong Chen, Yugang Liu, Zhitang Yang. Meta-analysis: combination of meropenem vs ceftazidime and amikacin for empirical treatment of cancer patients with febrile neutropenia. Medicine. 2021 Feb; 100(8):e24883. doi: 10.1097/md.0000000000024883. [PMID: 33663117]
  • Roccaldo Sardella, Styliani Xiroudaki, Laura Mercolini, Samuele Sabbatini, Claudia Monari, Stefano Perito, Federica Ianni, Anna Vecchiarelli, Stefano Giovagnoli. Optimized Extraction of Amikacin from Murine Whole Blood. Molecules (Basel, Switzerland). 2021 Jan; 26(3):. doi: 10.3390/molecules26030665. [PMID: 33513993]
  • Tamara van Donge, Anne Smits, John van den Anker, Karel Allegaert. Amikacin or Vancomycin Exposure Alters the Postnatal Serum Creatinine Dynamics in Extreme Low Birth Weight Neonates. International journal of environmental research and public health. 2021 01; 18(2):. doi: 10.3390/ijerph18020662. [PMID: 33466764]
  • Ilanthamizhan Jayakumar, Jayanthi Mathaiyan, Jharna Mandal, Surendran Deepanjali, Sreerag K Sreenivasan. Impact of Therapeutic Drug Monitoring on Once-Daily Regimen of Amikacin in Patients With Urinary Tract Infection: A Prospective Observational Study. Therapeutic drug monitoring. 2020 12; 42(6):841-847. doi: 10.1097/ftd.0000000000000800. [PMID: 32947556]
  • Jesús Chato-Astrain, Isabel Chato-Astrain, David Sánchez-Porras, Óscar-Darío García-García, Fabiola Bermejo-Casares, Claudia Vairo, María Villar-Vidal, Garazi Gainza, Silvia Villullas, Roke-Iñaki Oruezabal, Ángela Ponce-Polo, Ingrid Garzón, Víctor Carriel, Fernando Campos, Miguel Alaminos. Generation of a novel human dermal substitute functionalized with antibiotic-loaded nanostructured lipid carriers (NLCs) with antimicrobial properties for tissue engineering. Journal of nanobiotechnology. 2020 Nov; 18(1):174. doi: 10.1186/s12951-020-00732-0. [PMID: 33228673]
  • Iris H Chen, David P Nicolau, Joseph L Kuti. Imipenem/Cilastatin/Relebactam Alone and in Combination against Pseudomonas aeruginosa in the In Vitro Pharmacodynamic Model. Antimicrobial agents and chemotherapy. 2020 11; 64(12):. doi: 10.1128/aac.01764-20. [PMID: 33139283]
  • Mengya Li, Lingyun Ma, Chaoyang Chen, Lili Lei, Xingyu Zhai, Daohuang Luo, Ying Zhou, Yimin Cui. Evaluation of Assays to Measure Aminoglycosides in Serum: Comparison of Accuracy and Precision Based on External Quality Assessment. Therapeutic drug monitoring. 2020 10; 42(5):710-715. doi: 10.1097/ftd.0000000000000752. [PMID: 32118804]
  • C Vairo, J Basas, M Pastor, M Palau, X Gomis, B Almirante, E Gainza, R M Hernandez, M Igartua, J Gavaldà, G Gainza. In vitro and in vivo antimicrobial activity of sodium colistimethate and amikacin-loaded nanostructured lipid carriers (NLC). Nanomedicine : nanotechnology, biology, and medicine. 2020 10; 29(?):102259. doi: 10.1016/j.nano.2020.102259. [PMID: 32619707]
  • Eva A Edward, Nelly M Mohamed, Azza S Zakaria. Resensitization of Fluconazole-Resistant Urinary Candida spp. Isolates by Amikacin through Downregulation of Efflux Pump Genes. Polish journal of microbiology. 2020 Sep; 69(1):73-84. doi: 10.33073/pjm-2020-010. [PMID: 32189482]
  • Narges Fatemi, Mohammad Reza Sharifmoghadam, Masoumeh Bahreini, Bahman Khameneh, Hanieh Shadifar. Antibacterial and Synergistic Effects of Herbal Extracts in Combination with Amikacin and Imipenem Against Multidrug-Resistant Isolates of Acinetobacter. Current microbiology. 2020 Sep; 77(9):1959-1967. doi: 10.1007/s00284-020-02105-0. [PMID: 32623484]
  • Aaron J Heffernan, Fekade B Sime, Derek S Sarovich, Michael Neely, Yarmarly Guerra-Valero, Saiyuri Naicker, Kyra Cottrell, Patrick Harris, Katherine T Andrews, David Ellwood, Steven C Wallis, Jeffrey Lipman, Keith Grimwood, Jason A Roberts. Pharmacodynamic Evaluation of Plasma and Epithelial Lining Fluid Exposures of Amikacin against Pseudomonas aeruginosa in a Dynamic In Vitro Hollow-Fiber Infection Model. Antimicrobial agents and chemotherapy. 2020 08; 64(9):. doi: 10.1128/aac.00879-20. [PMID: 32660986]
  • Katrina Chan, Kimberly R Ledesma, Weiqun Wang, Vincent H Tam. Characterization of Amikacin Drug Exposure and Nephrotoxicity in an Animal Model. Antimicrobial agents and chemotherapy. 2020 08; 64(9):. doi: 10.1128/aac.00859-20. [PMID: 32571819]
  • Catarina M Silva, Andrew A Udy, João P Baptista. Urinary Creatinine Clearance and Pharmacokinetics Studies: If We Can Measure It, Why Do We Estimate It?. Antimicrobial agents and chemotherapy. 2020 08; 64(9):. doi: 10.1128/aac.00980-20. [PMID: 32571825]
  • Jonás Samuel Pérez-Blanco, Eva María Sáez Fernández, M Victoria Calvo, José M Lanao, Ana Martín-Suárez. Amikacin initial dosage in patients with hypoalbuminaemia: an interactive tool based on a population pharmacokinetic approach. The Journal of antimicrobial chemotherapy. 2020 08; 75(8):2222-2231. doi: 10.1093/jac/dkaa158. [PMID: 32363405]
  • Irene Galani, Vassiliki Papoutsaki, Irene Karantani, Ilias Karaiskos, Lamprini Galani, Panagiota Adamou, Ioannis Deliolanis, Antigoni Kodonaki, Eleni Papadogeorgaki, Margarita Markopoulou, Sofia Maraki, Maria Damala, Eleni Prifti, Eleni Vagiakou, Efthimia Petinaki, Kimon Fountoulis, Sophia Tsiplakou, Helen Kirikou, Maria Souli, Anastasia Antoniadou, Helen Giamarellou. In vitro activity of ceftolozane/tazobactam alone and in combination with amikacin against MDR/XDR Pseudomonas aeruginosa isolates from Greece. The Journal of antimicrobial chemotherapy. 2020 08; 75(8):2164-2172. doi: 10.1093/jac/dkaa160. [PMID: 32449909]
  • Kukwah Anthony Tufon, Djike Puepi Yolande Fokam, Youmbi Sylvain Kouanou, Henry Dilonga Meriki. Case report on a swift shift in uropathogens from Shigella flexneri to Escherichia coli: a thin line between bacterial persistence and reinfection. Annals of clinical microbiology and antimicrobials. 2020 Jul; 19(1):31. doi: 10.1186/s12941-020-00374-y. [PMID: 32727466]
  • Xiaocui Wu, Rongliang Gao, Xin Shen, Yinjuan Guo, Jinghui Yang, Zheyuan Wu, Guangkun Tan, Hongxiu Wang, Fangyou Yu. Use of whole-genome sequencing to predict Mycobacterium tuberculosis drug resistance in Shanghai, China. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2020 Jul; 96(?):48-53. doi: 10.1016/j.ijid.2020.04.039. [PMID: 32339720]
  • Juliano Gasparetto, Raphael Pitta, Kassia Cordova, Katiana Garcia Kaczam, Camila Mariye de Azevedo Takara, Guilherme Leite Zanini, Marcela Abujamra, Juliette Cieslinski, Thyago Proença de Moraes, Felipe Francisco Tuon. Acute Kidney Injury in Patients Using Amikacin in Intensive Care Unit-A Paired Case-Control Study With Meropenem. American journal of therapeutics. 2020 Jul; 27(4):e403-e405. doi: 10.1097/mjt.0000000000000955. [PMID: 32000249]
  • Brian M Hoff, Marc H Scheetz, Manu Jain, Joanne F Cullina, Nathaniel J Rhodes. Exploring the Relationship between FEV1 Loss and Recovery and Aminoglycoside Pharmacokinetics in Adult Patients with Cystic Fibrosis: Implications for Clinical Dosing Strategies. Pharmacotherapy. 2020 06; 40(6):584-591. doi: 10.1002/phar.2399. [PMID: 32259317]
  • Anne Caroline Cezimbra da Silva, Lilian de Lima Feltraco Lizot, Marcos Frank Bastiani, Marina Venzon Antunes, Natália Brucker, Rafael Linden. Dried plasma spots for therapeutic monitoring of amikacin: Validation of an UHPLC-MS/MS assay and pharmacokinetic application. Journal of pharmaceutical and biomedical analysis. 2020 May; 184(?):113201. doi: 10.1016/j.jpba.2020.113201. [PMID: 32113122]
  • Norma A Aréchiga-Alvarado, Susanna E Medellín-Garibay, Rosa Del C Milán-Segovia, Arturo Ortiz-Álvarez, Martín Magaña-Aquino, Silvia Romano-Moreno. Population Pharmacokinetics of Amikacin Administered Once Daily in Patients with Different Renal Functions. Antimicrobial agents and chemotherapy. 2020 04; 64(5):. doi: 10.1128/aac.02178-19. [PMID: 32041715]
  • Farhad Najmeddin, Bita Shahrami, Sayna Azadbakht, Mehrnoush Dianatkhah, Mohammad Reza Rouini, Atabak Najafi, Arezoo Ahmadi, Hamidreza Sharifnia, Mojtaba Mojtahedzadeh. Evaluation of Epithelial Lining Fluid Concentration of Amikacin in Critically Ill Patients With Ventilator-Associated Pneumonia. Journal of intensive care medicine. 2020 Apr; 35(4):400-404. doi: 10.1177/0885066618754784. [PMID: 29471721]
  • Katrina Chan, Weiqun Wang, Kimberly R Ledesma, Taijun Yin, Vincent H Tam. A robust LC-MS/MS method for amikacin: application to cellular uptake and pharmacokinetic studies. Bioanalysis. 2020 Apr; 12(7):445-454. doi: 10.4155/bio-2020-0007. [PMID: 32343148]
  • Nesibe Korkmaz, Yunus Gurbuz, Fatih Sandikci, Gülnur Kul, Emin Ediz Tutuncu, Irfan Sencan. The Role of Ciprofloxacin Resistance and Extended-spectrum beta-lactamase (ESBL) Positivity in Infective Complications Following Prostate Biopsy. Urology journal. 2020 03; 17(2):192-197. doi: 10.22037/uj.v0i0.4755. [PMID: 31364100]
  • Jadson Soares Laudelino, Flávio Teles Farias Filho, André Falcão Pedrosa Costa, Vitorino Modesto Santos. Mycobacterium abscessus urinary tract infection: case report. Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia. 2020 Mar; 42(1):124-126. doi: 10.1590/2175-8239-jbn-2018-0260. [PMID: 31173040]
  • Mahmut Demir, Halil Kazanasmaz. Uropathogens and antibiotic resistance in the community and hospital-induced urinary tract infected children. Journal of global antimicrobial resistance. 2020 03; 20(?):68-73. doi: 10.1016/j.jgar.2019.07.019. [PMID: 31340182]
  • Šárka Studená, Eva Doleželová, Jolana Cermanová, Alena Prašnická, Drahomíra Springer, Stanislav Mičuda, Jaroslav Chládek. Evaluation of Neutrophil Gelatinase-Associated Lipocalin as a Predictor of Glomerular Filtration Rate and Amikacin Clearance During Early Rat Endotoxemia: Comparison with Traditional Endogenous and Exogenous Biomarkers. European journal of drug metabolism and pharmacokinetics. 2020 Feb; 45(1):71-80. doi: 10.1007/s13318-019-00579-3. [PMID: 31605364]
  • Jacqueline M Ogier, Paul J Lockhart, Rachel A Burt. Intravenously delivered aminoglycoside antibiotics, tobramycin and amikacin, are not ototoxic in mice. Hearing research. 2020 02; 386(?):107870. doi: 10.1016/j.heares.2019.107870. [PMID: 31864009]
  • M K Ozer, S Bilgic, I Armagan, M Savran. Thymoquinone protection from amikacin induced renal injury in rats. Biotechnic & histochemistry : official publication of the Biological Stain Commission. 2020 Feb; 95(2):129-136. doi: 10.1080/10520295.2019.1650957. [PMID: 31502890]
  • N Mbelle, J Osei Sekyere, C Feldman, N E Maningi, L Modipane, S Y Essack. Genomic analysis of two drug-resistant clinical Morganella morganii strains isolated from UTI patients in Pretoria, South Africa. Letters in applied microbiology. 2020 Jan; 70(1):21-28. doi: 10.1111/lam.13237. [PMID: 31630429]
  • Wan Xuan Selina Lim, Wen Bing Brandon Chua, Jie Min Chua, Qianyu Lee, Jer Wei Chan, Rehena Sultana, Bao Hui Poh. A Retrospective Review of the Efficiency of First-Dose Therapeutic Drug Monitoring of Gentamicin, Amikacin, and Vancomycin in the Pediatric Population. Journal of clinical pharmacology. 2020 01; 60(1):7-15. doi: 10.1002/jcph.1509. [PMID: 31448430]
  • E Dvořáčková, P Pávek, B Kováčová, J Rychlíčková, O Suchopár, M Hojný, J D Tebbens, J Vlček. Is computer-assisted aminoglycoside dosing managed by a pharmacist a safety tool of pharmacotherapy?. Physiological research. 2019 11; 68(Suppl 1):S87-S96. doi: 10.33549/physiolres.934329. [PMID: 31755294]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Paulo Caceres Guido, Mariel Perez, Alicia Halac, Mariela Ferrari, Manuel Ibarra, Nieves Licciardone, Claudio Castaños, Luis P Gravina, Cristina Jimenez, Facundo Garcia Bournissen, Paula Schaiquevich. Population pharmacokinetics of amikacin in patients with pediatric cystic fibrosis. Pediatric pulmonology. 2019 11; 54(11):1801-1810. doi: 10.1002/ppul.24468. [PMID: 31402602]
  • Naomi E Crabtree, Cathleen A Mochal-King, Pearce B Sloan, Alison L Eddy, Robert W Wills, Ashley N Meredith, Robin L Fontenot. Synovial butorphanol concentrations and mechanical nociceptive thresholds after intravenous regional limb perfusion in standing sedated horses. Veterinary surgery : VS. 2019 Nov; 48(8):1473-1482. doi: 10.1111/vsu.13309. [PMID: 31513300]
  • Ana C A Silva, Jefferson S Diodato, José W Castro, Edinardo F F Matias, Luiz E Silva, Wanderlei do Amaral, Beatriz Helena L N S Maia, Aurea P Ferriani, Amanda K Souza, Lucindo J Quintans-Júnior, Henrique D M Coutinho. Effect of the essential oils from Piper sp. and blue led lights in the enhancement of the antibiotic activity of drugs against mdr bacterial strains. Journal of photochemistry and photobiology. B, Biology. 2019 Oct; 199(?):111604. doi: 10.1016/j.jphotobiol.2019.111604. [PMID: 31473430]
  • Adrien Bouglé, Olivier Dujardin, Victoria Lepère, Nora Ait Hamou, Charles Vidal, Guillaume Lebreton, Joe-Elie Salem, Najoua El-Helali, Grégoire Petijean, Julien Amour. PHARMECMO: Therapeutic drug monitoring and adequacy of current dosing regimens of antibiotics in patients on Extracorporeal Life Support. Anaesthesia, critical care & pain medicine. 2019 10; 38(5):493-497. doi: 10.1016/j.accpm.2019.02.015. [PMID: 30831307]
  • Dong-Jin Kim, Junho Lee, Hoon Yu, Dong-Hwan Lee, Taehan Kang, Young Kyu Han, Dong Hwi Kim, So Won Kim. Nephrotoxicity of amikacin in noncritically ill patients
. Clinical nephrology. 2019 Oct; 92(4):201-207. doi: 10.5414/cn109761. [PMID: 31347498]
  • Anne Caroline Cezimbra da Silva, Lilian de Lima Feltraco Lizot, Marcos Frank Bastiani, Marina Venzon Antunes, Natália Brucker, Rafael Linden. Ready for TDM: Simultaneous quantification of amikacin, vancomycin and creatinine in human plasma employing ultra-performance liquid chromatography-tandem mass spectrometry. Clinical biochemistry. 2019 Aug; 70(?):39-45. doi: 10.1016/j.clinbiochem.2019.06.011. [PMID: 31228434]
  • Hirokazu Nakayama, Masahiro Suzuki, Kensuke Usuki, Toshiaki Kato. Amikacin Pharmacokinetics in Terminal Stage of Hematological Malignancy. Therapeutic drug monitoring. 2019 08; 41(4):533-537. doi: 10.1097/ftd.0000000000000621. [PMID: 30817701]
  • Eva María Sáez Fernández, Jonás Samuel Pérez-Blanco, José M Lanao, M Victoria Calvo, Ana Martín-Suárez. Evaluation of renal function equations to predict amikacin clearance. Expert review of clinical pharmacology. 2019 Aug; 12(8):805-813. doi: 10.1080/17512433.2019.1637253. [PMID: 31242039]
  • Antoine Guillon, François Darrouzain, Nathalie Heuzé-Vourc'h, Antoine Petitcollin, Céline Barc, Laurent Vecellio, Bénédicte Cormier, Philippe Lanotte, Pierre Sarradin, Pierre-François Dequin, Gilles Paintaud, Stephan Ehrmann. Intra-tracheal amikacin spray delivery in healthy mechanically ventilated piglets. Pulmonary pharmacology & therapeutics. 2019 08; 57(?):101807. doi: 10.1016/j.pupt.2019.101807. [PMID: 31102741]
  • Jian Wang, Shaun S Kumar, Catherine M Sherwin, Robert Ward, Gerri Baer, Gilbert J Burckart, Yaning Wang, Lynne P Yao. Renal Clearance in Newborns and Infants: Predictive Performance of Population-Based Modeling for Drug Development. Clinical pharmacology and therapeutics. 2019 06; 105(6):1462-1470. doi: 10.1002/cpt.1332. [PMID: 30565653]
  • Workineh Shibeshi, Anandi N Sheth, Addisu Admasu, Alemseged Beyene Berha, Zenebe Negash, Getnet Yimer. Nephrotoxicity and ototoxic symptoms of injectable second-line anti-tubercular drugs among patients treated for MDR-TB in Ethiopia: a retrospective cohort study. BMC pharmacology & toxicology. 2019 05; 20(1):31. doi: 10.1186/s40360-019-0313-y. [PMID: 31122273]
  • Javad Hassanzadeh, Babak Rezaei Moghadam, Ali Sobhani-Nasab, Farhad Ahmadi, Mehdi Rahimi-Nasrabadi. Specific fluorometric assay for direct determination of amikacin by molecularly imprinting polymer on high fluorescent g-C3N4 quantum dots. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2019 May; 214(?):451-458. doi: 10.1016/j.saa.2019.02.067. [PMID: 30807943]
  • Wei Zhang, Shichun Lun, Ling-Ling Liu, Shiqi Xiao, Guanfu Duan, Hendra Gunosewoyo, Fan Yang, Jie Tang, William R Bishai, Li-Fang Yu. Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II. Journal of medicinal chemistry. 2019 04; 62(7):3575-3589. doi: 10.1021/acs.jmedchem.9b00010. [PMID: 30875203]
  • Maristela P Freire, Doroti de Oliveira Garcia, Ana Paula Cury, Gabriela R Francisco, Nathamy F Dos Santos, Fernanda Spadão, Maria Fernanda Campagnari Bueno, Carlos Henrique Camargo, Flavio J de Paula, Flavia Rossi, Willian C Nahas, Elias David-Neto, Ligia C Pierrotti. The role of therapy with aminoglycoside in the outcomes of kidney transplant recipients infected with polymyxin- and carbapenem-resistant Enterobacteriaceae. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 2019 Apr; 38(4):755-765. doi: 10.1007/s10096-019-03468-4. [PMID: 30680569]
  • Seth Kwabena Amponsah, Kwabena Frimpong-Manso Opuni, Kwabena Aboagye Antwi, Victor Pouzuing Kunkpeh. Effect of aminophylline on the pharmacokinetics of amikacin in Sprague-Dawley rats. Journal of infection in developing countries. 2019 03; 13(3):251-254. doi: 10.3855/jidc.10514. [PMID: 32040456]
  • Mohamed M Abdel-Daim, Amira Ahmed, Hira Ijaz, Abdelrahman Ibrahim Abushouk, Hussien Ahmed, Ahmed Negida, Lotfi Aleya, Simona G Bungau. Influence of Spirulina platensis and ascorbic acid on amikacin-induced nephrotoxicity in rabbits. Environmental science and pollution research international. 2019 Mar; 26(8):8080-8086. doi: 10.1007/s11356-019-04249-4. [PMID: 30685861]
  • Xiaoxi Liu, Anne Smits, Yuhuan Wang, Marleen Renard, Stephanie Wead, Richard J Kagan, Daniel P Healy, Pieter De Cock, Karel Allegaert, Catherine M T Sherwin. Impact of Disease on Amikacin Pharmacokinetics and Dosing in Children. Therapeutic drug monitoring. 2019 02; 41(1):44-52. doi: 10.1097/ftd.0000000000000568. [PMID: 30299427]
  • Aiju Endo, Atsushi Nemoto, Kazumi Hanawa, Yuki Maebayashi, Yohei Hasebe, Mami Kobayashi, Atsushi Naito, Yoshifumi Kobayashi, Seiichi Yamamoto, Katsuhiko Isobe. Relationship between amikacin blood concentration and ototoxicity in low birth weight infants. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2019 Jan; 25(1):17-21. doi: 10.1016/j.jiac.2018.10.001. [PMID: 30539740]
  • Sunayana Raya, Ankit Belbase, Laxmi Dhakal, Krishna Govinda Prajapati, Reena Baidya, Nabin Kishor Bimali. In-Vitro Biofilm Formation and Antimicrobial Resistance of Escherichia coli in Diabetic and Nondiabetic Patients. BioMed research international. 2019; 2019(?):1474578. doi: 10.1155/2019/1474578. [PMID: 31641666]
  • Anthony J Garcia-Prats, Penelope C Rose, Heather R Draper, James A Seddon, Jennifer Norman, Helen M McIlleron, Anneke C Hesseling, H Simon Schaaf. Effect of Coadministration of Lidocaine on the Pain and Pharmacokinetics of Intramuscular Amikacin in Children With Multidrug-Resistant Tuberculosis: A Randomized Crossover Trial. The Pediatric infectious disease journal. 2018 12; 37(12):1199-1203. doi: 10.1097/inf.0000000000001983. [PMID: 29561515]
  • Sílvia M Illamola, Hoa Q Huynh, Xiaoxi Liu, Zubin N Bhakta, Catherine M Sherwin, Theodore G Liou, Holly Carveth, David C Young. Population Pharmacokinetics of Amikacin in Adult Patients with Cystic Fibrosis. Antimicrobial agents and chemotherapy. 2018 10; 62(10):. doi: 10.1128/aac.00877-18. [PMID: 30061295]
  • Sandrine Marchand, Matthieu Boisson, Shachi Mehta, Christophe Adier, Olivier Mimoz, Nicolas Grégoire, William Couet. Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 6. Aminoglycosides. Antimicrobial agents and chemotherapy. 2018 10; 62(10):. doi: 10.1128/aac.01261-18. [PMID: 30082284]
  • Nafees Ahmad, Shama D Ahuja, Onno W Akkerman, Jan-Willem C Alffenaar, Laura F Anderson, Parvaneh Baghaei, Didi Bang, Pennan M Barry, Mayara L Bastos, Digamber Behera, Andrea Benedetti, Gregory P Bisson, Martin J Boeree, Maryline Bonnet, Sarah K Brode, James C M Brust, Ying Cai, Eric Caumes, J Peter Cegielski, Rosella Centis, Pei-Chun Chan, Edward D Chan, Kwok-Chiu Chang, Macarthur Charles, Andra Cirule, Margareth Pretti Dalcolmo, Lia D'Ambrosio, Gerard de Vries, Keertan Dheda, Aliasgar Esmail, Jennifer Flood, Gregory J Fox, Mathilde Fréchet-Jachym, Geisa Fregona, Regina Gayoso, Medea Gegia, Maria Tarcela Gler, Sue Gu, Lorenzo Guglielmetti, Timothy H Holtz, Jennifer Hughes, Petros Isaakidis, Leah Jarlsberg, Russell R Kempker, Salmaan Keshavjee, Faiz Ahmad Khan, Maia Kipiani, Serena P Koenig, Won-Jung Koh, Afranio Kritski, Liga Kuksa, Charlotte L Kvasnovsky, Nakwon Kwak, Zhiyi Lan, Christoph Lange, Rafael Laniado-Laborín, Myungsun Lee, Vaira Leimane, Chi-Chiu Leung, Eric Chung-Ching Leung, Pei Zhi Li, Phil Lowenthal, Ethel L Maciel, Suzanne M Marks, Sundari Mase, Lawrence Mbuagbaw, Giovanni B Migliori, Vladimir Milanov, Ann C Miller, Carole D Mitnick, Chawangwa Modongo, Erika Mohr, Ignacio Monedero, Payam Nahid, Norbert Ndjeka, Max R O'Donnell, Nesri Padayatchi, Domingo Palmero, Jean William Pape, Laura J Podewils, Ian Reynolds, Vija Riekstina, Jérôme Robert, Maria Rodriguez, Barbara Seaworth, Kwonjune J Seung, Kathryn Schnippel, Tae Sun Shim, Rupak Singla, Sarah E Smith, Giovanni Sotgiu, Ganzaya Sukhbaatar, Payam Tabarsi, Simon Tiberi, Anete Trajman, Lisa Trieu, Zarir F Udwadia, Tjip S van der Werf, Nicolas Veziris, Piret Viiklepp, Stalz Charles Vilbrun, Kathleen Walsh, Janice Westenhouse, Wing-Wai Yew, Jae-Joon Yim, Nicola M Zetola, Matteo Zignol, Dick Menzies. Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis. Lancet (London, England). 2018 09; 392(10150):821-834. doi: 10.1016/s0140-6736(18)31644-1. [PMID: 30215381]
  • Murat Dogan, Mustafa Sahin, Nesibe Cetin, Mustafa Yilmaz, Buket Demirci. Utilizing prestin as a predictive marker for the early detection of outer hair cell damage. American journal of otolaryngology. 2018 Sep; 39(5):594-598. doi: 10.1016/j.amjoto.2018.07.007. [PMID: 30025743]
  • Jesus Ruiz-Ramos, Ricardo Gimeno, Francisca Pérez, Paula Ramirez, Esther Villarreal, Monica Gordon, Carlos Vicent, María Remedios Marqués, Álvaro Castellanos-Ortega. Pharmacokinetics of Amikacin in Critical Care Patients on Extracorporeal Device. ASAIO journal (American Society for Artificial Internal Organs : 1992). 2018 Sep; 64(5):686-688. doi: 10.1097/mat.0000000000000689. [PMID: 29045281]