2-Phospho-D-glyceric acid (BioDeep_00000003412)

Main id: BioDeep_00000018614

Secondary id: BioDeep_00001868854

human metabolite Endogenous natural product


代谢物信息卡片


(2R)-3-Hydroxy-2-(phosphonooxy)propanoic acid

化学式: C3H7O7P (185.9929402)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 0.04%

分子结构信息

SMILES: C(C(C(=O)O)OP(=O)(O)O)O
InChI: InChI=1S/C3H7O7P/c4-1-2(3(5)6)10-11(7,8)9/h2,4H,1H2,(H,5,6)(H2,7,8,9)/t2-/m1/s1

描述信息

2-Phosphoglyceric acid (2PG), or 2-phosphoglycerate, is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penultimate step in the conversion of glucose to pyruvate.; 2-Phosphoglyceric acid (2PGA) is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penultimate step in the conversion of glucose to pyruvate. Enolase catalyzes the beta-elimination reaction in a stepwise manner wherein OH- is eliminated from C3 of a discrete carbanion (enolate) intermediate. This intermediate is created by removal of the proton from C2 of 2PGA by a base in the active site. (PMID: 8994873, Wikipedia). 2-Phosphoglycerate is found in rice.
2-Phospho-D-glycerate or 2PG is an intermediate in gluconeogenesis. It is a glyceric acid which serves as the substrate in the ninth step of glycolysis. 2PG is converted by enolase into phosphoenolpyruvate (PEP), the penultimate step in the conversion of glucose to pyruvate. More specifically, 2PG can be generated from Glycerate-3-phosphate via phosphoglycerate mutase or from phosphoenolpyrvate via alpha enolase.
KEIO_ID P029

同义名列表

16 个代谢物同义名

(2R)-3-Hydroxy-2-(phosphonooxy)propanoic acid; 3-D-Hydroxy-2-phosphonooxy-propanoic acid; (2R)-3-Hydroxy-2-(phosphonooxy)propanoate; 3-D-Hydroxy-2-phosphonooxy-propanoate; D-Glyceric acid 2-phosphoric acid; D-(+)-2-Phosphoglyceric acid; D-Glyceric acid 2-phosphate; 2-Phospho-(R)-glyceric acid; 2-Phospho-D-glyceric acid; D-2-Phosphoglyceric acid; (+-)-2-phosphoglycerate; 2-Phospho-(R)-glycerate; D-Glycerate 2-phosphate; 2-phosphoglyceric acid; 2-phospho-D-Glycerate; 2-phosphoglycerate



数据库引用编号

27 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(6)

PlantCyc(0)

代谢反应

103 个相关的代谢反应过程信息。

Reactome(15)

BioCyc(22)

WikiPathways(3)

Plant Reactome(0)

INOH(3)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(60)

PharmGKB(0)

10 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ipsita Pal Bhowmick, Nirbhay Kumar, Shobhona Sharma, Isabelle Coppens, Gotam K Jarori. Plasmodium falciparum enolase: stage-specific expression and sub-cellular localization. Malaria journal. 2009 Jul; 8(?):179. doi: 10.1186/1475-2875-8-179. [PMID: 19642995]