9,13-cis-Retinoic acid (BioDeep_00000032760)

Main id: BioDeep_00000001595

 

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


(2Z,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid

化学式: C20H28O2 (300.2089188)
中文名称: 维A酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C(O)=O)=C(C)CCC1
InChI: InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+

描述信息

9,13-cis-Retinoic acid belongs to the class of organic compounds known as retinoids. These are oxygenated derivatives of 3,7-dimethyl-1-(2,6,6-trimethylcyclohex-1-enyl)nona-1,3,5,7-tetraene and derivatives thereof. Retinoids (vitamin A and its analogs) are essential dietary substances that are needed by mammals for reproduction, normal embryogenesis, growth, vision, and maintaining normal cellular differentiation and the integrity of the immune system. Within cells, retinoids regulate gene transcription acting through ligand-dependent transcription factors, the retinoic acid receptors (RARs), and the retinoid X receptors (RXRs).
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). Retinoids such as tretinoin are important regulators of cell reproduction, proliferation, and differentiation and are used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. Tretinoin also represents the class of anticancer drugs called differentiating agents and is used in the treatment of acute promyelocytic leukemia (APL). [HMDB]
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01X - Other antineoplastic agents > L01XF - Retinoids for cancer treatment
D - Dermatologicals > D10 - Anti-acne preparations > D10A - Anti-acne preparations for topical use > D10AD - Retinoids for topical use in acne
C274 - Antineoplastic Agent > C2122 - Cell Differentiating Agent > C1934 - Differentiation Inducer
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C804 - Retinoic Acid Agent
C308 - Immunotherapeutic Agent > C129820 - Antineoplastic Immunomodulating Agent
D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
D003879 - Dermatologic Agents > D007641 - Keratolytic Agents
D000970 - Antineoplastic Agents
Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.

同义名列表

20 个代谢物同义名

(2Z,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-(2E,4Z,6E,8Z)-nonatetraen-1-Oic acid; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-(2E,4Z,6E,8Z)-nonatetraen-1-Oate; 9,13-cis-Retinoic acid anion; 9,13-cis-Vitamin-alpha-acid; 9-cis,13-cis-Retinoic acid; 9,13-di-cis-retinoic acid; 9,13-cis-Vitamin-a-acid; 9-cis,13-cis-Retinoate; 9,13-cis-Retinoic acid; 9,13-Di-cis-retinoate; 9,13-cis-Retinoate; 9,13-Retinoic acid; 9,13-Di-cis-ra; Tretinoin; DcVA; Vitamin A acid; all-trans-Retinoic acid; ATRA; Retinoic acid



数据库引用编号

20 个数据库交叉引用编号

分类词条

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yoshihiro Shidoji. Induction of Hepatoma Cell Pyroptosis by Endogenous Lipid Geranylgeranoic Acid-A Comparison with Palmitic Acid and Retinoic Acid. Cells. 2024 May; 13(10):. doi: 10.3390/cells13100809. [PMID: 38786033]
  • Lindsay C Czuba, Nina Isoherranen. LX-2 Stellate Cells Are a Model System for Investigating the Regulation of Hepatic Vitamin A Metabolism and Respond to Tumor Necrosis Factor α and Interleukin 1β. Drug metabolism and disposition: the biological fate of chemicals. 2024 Apr; 52(5):442-454. doi: 10.1124/dmd.124.001679. [PMID: 38485281]
  • Yuki Mori, Masashi Masuda, Risa Yoshida-Shimizu, Saki Aoyagi, Yuichiro Adachi, Anh The Nguyen, Yusuke Maruyama, Yosuke Okumura, Yuki Kamei, Maiko Sakai, Kohta Ohnishi, Hirokazu Ohminami, Yutaka Taketani. All-trans retinoic acid induces lipophagy through the activation of the AMPK-Beclin1 signaling pathway and reduces Rubicon expression in adipocytes. The Journal of nutritional biochemistry. 2024 Apr; 126(?):109589. doi: 10.1016/j.jnutbio.2024.109589. [PMID: 38295886]
  • Cheng Zhang, Lite Ge, Huali Xie, Xiaoqian Liu, Chengfeng Xun, Yan Chen, Haiyan Chen, Ming Lu, Ping Chen. Retinoic acid induced specific changes in the phosphoproteome of C17.2 neural stem cells. Journal of cellular and molecular medicine. 2024 Apr; 28(7):e18205. doi: 10.1111/jcmm.18205. [PMID: 38506089]
  • Samuel Kesse, Yuhong Xu, Sanyuan Shi, Shanshan Jin, Shafi Ullah, Yongchao Dai, Miao He, Anjie Zheng, Fengwei Xu, Zixiu Du, Raphael N Alolga, Jinliang Peng. MDSC-targeted liposomal all-trans retinoic acid suppresses mMdscs and improves immunotherapy in HBV infection. Expert opinion on drug delivery. 2024 Feb; 21(2):347-363. doi: 10.1080/17425247.2024.2317936. [PMID: 38406829]
  • Li Sun, Meifang Zheng, Yanhang Gao, David R Brigstock, Runping Gao. Retinoic acid signaling pathway in pancreatic stellate cells: Insight into the anti-fibrotic effect and mechanism. European journal of pharmacology. 2024 Feb; ?(?):176374. doi: 10.1016/j.ejphar.2024.176374. [PMID: 38309676]
  • Suting Xiao, Yizhen Yan, Mingyin Shao, Xuan Zhou, Zhenyu Niu, Yanli Wu, Yanwu Li, Yong Cui, Yu Long, Qun Du. Kuijieling decoction regulates the Treg/Th17 cell balance in ulcerative colitis through the RA/RARα signaling pathway. Journal of ethnopharmacology. 2024 Jan; 318(Pt A):116909. doi: 10.1016/j.jep.2023.116909. [PMID: 37451490]
  • Feifan Wu, Ruichao Chen, Yu Li, Yi Wan, Jianying Hu. Unregistered Hexaphenoxycyclotriphosphazene and Its Metabolite Antagonize Retinoic Acid and Retinoic X Receptors and Cause Early Developmental Damage. Environmental science & technology. 2023 Dec; 57(49):20551-20558. doi: 10.1021/acs.est.3c07997. [PMID: 38037888]
  • Wensheng Wang, Lin Wang. Protective effect of tretinoin derivative and TXNRD1 protein on streptozotocin induced gestational diabetes via an age-rage signaling-pathway. Acta biochimica Polonica. 2023 Dec; 70(4):985-990. doi: 10.18388/abp.2020_6947. [PMID: 38060807]
  • Dan-Ping Huang, Liang-Chun Yang, Yi-Qiao Chen, Wu-Qing Wan, Dun-Hua Zhou, Hui-Rong Mai, Wan-Li Li, Li-Hua Yang, He-Kui Lan, Hui-Qin Chen, Bi-Yun Guo, Zi-Jun Zhen, Ri-Yang Liu, Guo-Hua Chen, Xiao-Qin Feng, Cong Liang, Li-Na Wang, Yu Li, Jie-Si Luo, Zhong Fan, Xue-Qun Luo, Bin Li, Yan-Lai Tang, Xiao-Li Zhang, Li-Bin Huang. Long-term outcome of children with acute promyelocytic leukemia: a randomized study of oral versus intravenous arsenic by SCCLG-APL group. Blood cancer journal. 2023 12; 13(1):178. doi: 10.1038/s41408-023-00949-w. [PMID: 38052803]
  • Jixin Chen, Shuqi Chen, Huiyan Luo, Wanyin Wu, Sumei Wang. The application of arsenic trioxide in cancer: An umbrella review of meta-analyses based on randomized controlled trials. Journal of ethnopharmacology. 2023 Nov; 316(?):116734. doi: 10.1016/j.jep.2023.116734. [PMID: 37290735]
  • Baldeep Singh, Isha Pahuja, Priyanka Yadav, Aishwarya Shaji, Shivam Chaturvedi, Anand Ranganathan, Ved Prakash Dwivedi, Gobardhan Das. Adjunct therapy with all-trans-retinoic acid improves therapeutic efficacy through immunomodulation while treating tuberculosis with antibiotics in a murine model. The Journal of infectious diseases. 2023 Oct; ?(?):. doi: 10.1093/infdis/jiad460. [PMID: 37863472]
  • Jacqueline Taylor, Leonie Uhl, Iris Moll, Sana Safatul Hasan, Lena Wiedmann, Jakob Morgenstern, Benedetto Daniele Giaimo, Tobias Friedrich, Elisenda Alsina-Sanchis, Francesca De Angelis Rigotti, Ronja Mülfarth, Sarah Kaltenbach, Darius Schenk, Felix Nickel, Thomas Fleming, David Sprinzak, Carolin Mogler, Thomas Korff, Adrian T Billeter, Beat P Müller-Stich, Mauricio Berriel Diaz, Tilman Borggrefe, Stephan Herzig, Maria Rohm, Juan Rodriguez-Vita, Andreas Fischer. Endothelial Notch1 signaling in white adipose tissue promotes cancer cachexia. Nature cancer. 2023 Sep; ?(?):. doi: 10.1038/s43018-023-00622-y. [PMID: 37749321]
  • Hamed Rezaie, Reza Alipanah-Moghadam, Farhad Jeddi, Cain C T Clark, Vahideh Aghamohammadi, Ali Nemati. Combined dandelion extract and all-trans retinoic acid induces cytotoxicity in human breast cancer cells. Scientific reports. 2023 Sep; 13(1):15074. doi: 10.1038/s41598-023-42177-z. [PMID: 37700002]
  • Jakub Maciej Surmacki, Halina Abramczyk. Confocal Raman imaging reveals the impact of retinoids on human breast cancer via monitoring the redox status of cytochrome c. Scientific reports. 2023 Sep; 13(1):15049. doi: 10.1038/s41598-023-42301-z. [PMID: 37700001]
  • Yin-Ku Lin, Chien-Yu Hsiao, Abdullah Alshetaili, Ibrahim A Aljuffali, En-Li Chen, Jia-You Fang. Lipid-based nanoformulation optimization for achieving cutaneous targeting: Niosomes as the potential candidates to fulfill this aim. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2023 Jul; 186(?):106458. doi: 10.1016/j.ejps.2023.106458. [PMID: 37137418]
  • Samiksha Sardana, Anneroos E Nederstigt, Marc P Baggelaar. S-Palmitoylation during Retinoic Acid-Induced Neuronal Differentiation of SH-SY5Y Neuroblastoma Cells. Journal of proteome research. 2023 Jun; ?(?):. doi: 10.1021/acs.jproteome.3c00151. [PMID: 37294931]
  • Xueyan Li, Xiaoqi Luo, Siru Chen, Jiayi Chen, Xue Deng, Jiahui Zhong, Hui Wu, Xuhui Huang, Changjun Wang. All-trans-retinoic acid inhibits hepatocellular carcinoma progression by targeting myeloid-derived suppressor cells and inhibiting angiogenesis. International immunopharmacology. 2023 Jun; 121(?):110413. doi: 10.1016/j.intimp.2023.110413. [PMID: 37301119]
  • Xudong Shan, Xueguang Zhang, Gelin Huang, Jiao Lv, Zixia Ye, Chuan Jiang, Xiaohui Jiang, Jianxing Cheng, Haocheng Lin, Hui Jiang, Huanxun Yue, Zhengrong Wang, Wenming Xu. A novel SNP in HUWE1 promoter confers increased risk of NOA by affecting the RA/RARα pathway in Chinese individuals. Andrology. 2023 Jun; ?(?):. doi: 10.1111/andr.13474. [PMID: 37290064]
  • Wen Cui, Zheng Xue, Ling-Ling Zhao, Ying Li, Jian-Qing Mi. [Effect of a Novel Dihydroartemisinin Dimer Containing Nitrogen Atoms SM 1044 on Apoptosis of Human Leukemia Cell Line NB4-R1]. Zhongguo shi yan xue ye xue za zhi. 2023 Jun; 31(3):659-665. doi: 10.19746/j.cnki.issn.1009-2137.2023.03.007. [PMID: 37356923]
  • Rui Pedro Moura, Eva Daniela Carvalho, Cláudia Martins, Anne des Rieux, Ana Paula Pêgo, Bruno Sarmento. Functionalized retinoic acid lipid nanocapsules promotes a two-front attack on inflammation and lack of demyelination on neurodegenerative disorders. Journal of controlled release : official journal of the Controlled Release Society. 2023 06; 358(?):43-58. doi: 10.1016/j.jconrel.2023.04.034. [PMID: 37088306]
  • Leila Parsa, Rouhollah Motafakkerazad, Sarvin Taleb Soheyli, Amin Haratian, Morteza Kosari-Nasab, Majid Mahdavi. Silymarin in combination with ATRA enhances apoptosis induction in human acute promyelocytic NB4 cells. Toxicon : official journal of the International Society on Toxinology. 2023 Jun; 228(?):107127. doi: 10.1016/j.toxicon.2023.107127. [PMID: 37085055]
  • Md Jakaria, Abdel A Belaidi, Ashley I Bush, Scott Ayton. Vitamin A metabolites inhibit ferroptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 May; 164(?):114930. doi: 10.1016/j.biopha.2023.114930. [PMID: 37236031]
  • Xinliang Wang, Chanjuan Yang, Yanrong Li, Qiang Gong, Yi Ru, Liangqi Xie, Baoguo Xiao, Xiaoming Jin, Cungen Ma, Zhi Chai, Huijie Fan. Wuzi Yanzong Pill protects neural tube defects by activating PI3K/Akt signaling pathway. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2023 May; ?(?):. doi: 10.1002/jdn.10267. [PMID: 37211717]
  • Guoshu Bi, Jiaqi Liang, Guangyao Shan, Yunyi Bian, Zhencong Chen, Yiwei Huang, Tao Lu, Ming Li, Valeria Besskaya, Mengnan Zhao, Hong Fan, Qun Wang, Boyi Gan, Cheng Zhan. Retinol saturase mediates retinoid metabolism to impair a ferroptosis defense system in cancer cells. Cancer research. 2023 May; ?(?):. doi: 10.1158/0008-5472.can-22-3977. [PMID: 37184371]
  • Reza Zolfaghari, Jessica A Bonzo, Frank J Gonzalez, A Catharine Ross. Hepatocyte Nuclear Factor 4α (HNF4α) Plays a Controlling Role in Expression of the Retinoic Acid Receptor β (RARβ) Gene in Hepatocytes. International journal of molecular sciences. 2023 May; 24(10):. doi: 10.3390/ijms24108608. [PMID: 37239961]
  • Xinliang Wang, Chanjuan Yang, Yi Ru, Liangqi Xie, Baoguo Xiao, Xiaoming Jin, Cungen Ma, Zhi Chai, Huijie Fan. An optimal combination of five main monomer components in Wuzi Yanzong Pill that prevents neural tube defects and reduces apoptosis and oxidative stress. Journal of ethnopharmacology. 2023 Apr; 313(?):116540. doi: 10.1016/j.jep.2023.116540. [PMID: 37088238]
  • Yuan-Yuan Liu, Yun-Feng Ding, Hai-Juan Sui, Wei Liu, Zhen-Qiu Zhang, Feng Li. Pilose antler (Cervus elaphus Linnaeus) polysaccharide and polypeptide extract inhibits bone resorption in high turnover type osteoporosis by stimulating the MAKP and MMP-9 signaling pathways. Journal of ethnopharmacology. 2023 Mar; 304(?):116052. doi: 10.1016/j.jep.2022.116052. [PMID: 36529246]
  • Marzieh Moazeny, Moein Dehbashi, Zohreh Hojati, Fariba Esmaeili. Investigating neural differentiation of mouse P19 embryonic stem cells in a time-dependent manner by bioinformatic, microscopic and transcriptional analyses. Molecular biology reports. 2023 Mar; 50(3):2183-2194. doi: 10.1007/s11033-022-08166-7. [PMID: 36565416]
  • Xueni You, Tianjiao Li, Youjie Cui, Wei Liu, Zechao Cheng, Wenxian Zeng, Peng Wang, Yi Zheng. Retinoic acid-induced differentiation of porcine prospermatogonia in vitro. Theriogenology. 2023 Mar; 198(?):344-355. doi: 10.1016/j.theriogenology.2023.01.007. [PMID: 36640739]
  • Q N Ye, K Zheng. Expression and function of patatin-like phospholipase domain-containing 2 in cleft palate induced by retinoic acid. The British journal of oral & maxillofacial surgery. 2023 Feb; ?(?):. doi: 10.1016/j.bjoms.2023.02.002. [PMID: 36906446]
  • Jiayi Chen, Mei Li, Yeqing Liu, Tangming Guan, Xiao Yang, Yalei Wen, Yingjie Zhu, Zeyu Xiao, Xiangchun Shen, Haoxing Zhang, Hui Tang, Tongzheng Liu. PIN1 and CDK1 cooperatively govern pVHL stability and suppressive functions. Cell death and differentiation. 2023 Feb; ?(?):. doi: 10.1038/s41418-023-01128-x. [PMID: 36813923]
  • Eshani Karmakar, Nabanita Das, Bidisha Mukherjee, Prosenjit Das, Satinath Mukhopadhyay, Sib Sankar Roy. Lipid induced alteration in retinoic acid signaling leads to mitochondrial dysfunction in HepG2 and Huh7 cells. Biochemistry and cell biology = Biochimie et biologie cellulaire. 2023 Feb; ?(?):. doi: 10.1139/bcb-2022-0266. [PMID: 36787544]
  • Andréa Carolina Pinheiro de Freitas, Roberta Balansin Rigon, Ediléia Bagatin, Gislaine Ricci Leonardi. Perspectives of topical formulations for melasma. International journal of dermatology. 2023 Feb; 62(2):260-268. doi: 10.1111/ijd.16421. [PMID: 36083295]
  • Hongru Jia, Zhangqing Wu, Jianbing Tan, Silin Wu, Chaoqun Yang, Sayed Haidar Abbas Raza, Meng Wang, Guibing Song, Yujie Shi, Linsen Zan, Wucai Yang. Lnc-TRTMFS promotes milk fat synthesis via the miR-132x/RAI14/mTOR pathway in BMECs. Journal of animal science. 2023 Jan; 101(?):. doi: 10.1093/jas/skad218. [PMID: 37367933]
  • Yu-Zhen Tan, Hao-Ran Shen, Yong-Li Wang, Qiang-Li Wang, Xue-Ping Wu, Shu-Na Yu, Hai-Jie Wang. Retinoic acid released from self-assembling peptide activates cardiomyocyte proliferation and enhances repair of infarcted myocardium. Experimental cell research. 2023 01; 422(1):113440. doi: 10.1016/j.yexcr.2022.113440. [PMID: 36481206]
  • Jian-Yong Zhao, Xiang-Kun Yuan, Rui-Zhen Luo, Li-Xin Wang, Wei Gu, Daisuke Yamane, Hui Feng. Phospholipase A and acyltransferase 4/retinoic acid receptor responder 3 at the intersection of tumor suppression and pathogen restriction. Frontiers in immunology. 2023; 14(?):1107239. doi: 10.3389/fimmu.2023.1107239. [PMID: 37063830]
  • Dan Huang, Xia Qian, Jinqing Chen, Yating Peng, Yunxia Zhu. Factors and Molecular Mechanisms of Vitamin A and Childhood Obesity Relationship: A Review. Journal of nutritional science and vitaminology. 2023; 69(3):157-163. doi: 10.3177/jnsv.69.157. [PMID: 37394420]
  • Liang Qi, Han Han, Meng-Meng Han, Ying Sun, Lei Xing, Hu-Lin Jiang, Stephen J Pandol, Ling Li. Remodeling of imbalanced extracellular matrix homeostasis for reversal of pancreatic fibrosis. Biomaterials. 2023 01; 292(?):121945. doi: 10.1016/j.biomaterials.2022.121945. [PMID: 36508773]
  • Gabriel A Aguirre, Michelle R Goulart, Jesmond Dalli, Hemant M Kocher. Arachidonate 15-lipoxygenase-mediated production of Resolvin D5n-3 DPA abrogates pancreatic stellate cell-induced cancer cell invasion. Frontiers in immunology. 2023; 14(?):1248547. doi: 10.3389/fimmu.2023.1248547. [PMID: 38035115]
  • Ya-Ting Jiao, Wen-Shu Zhang, Shan-Shan Pan, Ming-Jie Xie. [Multi-omics analysis of regulating effects of hyperoside on lipid metabolism in high-fat diet mice]. Sheng li xue bao : [Acta physiologica Sinica]. 2022 Dec; 74(6):970-978. doi: ". [PMID: 36594385]
  • Zuzana Toušová, Jana Priebojová, Jakub Javůrek, Jaroslava Večerková, Olga Lepšová-Skácelová, Eliška Sychrová, Marie Smutná, Klára Hilscherová. Estrogenic and retinoid-like activity in stagnant waters with mass occurrence of water blooms. The Science of the total environment. 2022 Dec; 852(?):158257. doi: 10.1016/j.scitotenv.2022.158257. [PMID: 36037903]
  • Johana Coronel, Jianshi Yu, Nageswara Pilli, Maureen A Kane, Jaume Amengual. The conversion of β-carotene to vitamin A in adipocytes drives the anti-obesogenic effects of β-carotene in mice. Molecular metabolism. 2022 12; 66(?):101640. doi: 10.1016/j.molmet.2022.101640. [PMID: 36400405]
  • Shenglong Zhu, Jingwei Zhang, Doudou Zhu, Xuan Jiang, Lengyun Wei, Wei Wang, Yong Q Chen. Adipose tissue plays a major role in retinoic acid-mediated metabolic homoeostasis. Adipocyte. 2022 12; 11(1):47-55. doi: 10.1080/21623945.2021.2015864. [PMID: 34957917]
  • Zhengze Lu, Houqin Liu, Ling Ma, Kebai Ren, Zhidi He, Man Li, Qin He. Micellar nanoparticles inhibit breast cancer and pulmonary metastasis by modulating the recruitment and depletion of myeloid-derived suppressor cells. Nanoscale. 2022 Dec; 14(46):17315-17330. doi: 10.1039/d2nr03880c. [PMID: 36374496]
  • Caifeng Deng, Xuan Zhao, Yuxiao Chen, Kelong Ai, Yuqing Zhang, Tao Gong, Chao Zeng, Guanghua Lei. Engineered Platelet Microparticle-Membrane Camouflaged Nanoparticles for Targeting the Golgi Apparatus of Synovial Fibroblasts to Attenuate Rheumatoid Arthritis. ACS nano. 2022 11; 16(11):18430-18447. doi: 10.1021/acsnano.2c06584. [PMID: 36342327]
  • Elisa Maria Turco, Angela Maria Giada Giovenale, Laura Sireno, Martina Mazzoni, Alessandra Cammareri, Caterina Marchioretti, Laura Goracci, Alessandra Di Veroli, Elena Marchesan, Daniel D'Andrea, Antonella Falconieri, Barbara Torres, Laura Bernardini, Maria Chiara Magnifico, Alessio Paone, Serena Rinaldo, Matteo Della Monica, Stefano D'Arrigo, Diana Postorivo, Anna Maria Nardone, Giuseppe Zampino, Roberta Onesimo, Chiara Leoni, Federico Caicci, Domenico Raimondo, Elena Binda, Laura Trobiani, Antonella De Jaco, Ada Maria Tata, Daniela Ferrari, Francesca Cutruzzolà, Gianluigi Mazzoccoli, Elena Ziviani, Maria Pennuto, Angelo Luigi Vescovi, Jessica Rosati. Retinoic acid-induced 1 gene haploinsufficiency alters lipid metabolism and causes autophagy defects in Smith-Magenis syndrome. Cell death & disease. 2022 11; 13(11):981. doi: 10.1038/s41419-022-05410-7. [PMID: 36411275]
  • Venkatram R Atigadda, Mahendra P Kashyap, Zhengrong Yang, Debasish Chattopadhyay, Nathalia Melo, Rajesh Sinha, Olga V Belyaeva, Chu-Fang Chou, Pi-Ling Chang, Natalia Y Kedishvili, Clinton J Grubbs, Matthew B Renfrow, Donald D Muccio, Craig A Elmets, Mohammad Athar. Conformationally Defined Rexinoids for the Prevention of Inflammation and Nonmelanoma Skin Cancers. Journal of medicinal chemistry. 2022 11; 65(21):14409-14423. doi: 10.1021/acs.jmedchem.2c00735. [PMID: 36318154]
  • Woan-Ruoh Lee, Tse-Hung Huang, Sindy Hu, Ahmed Alalaiwe, Pei-Wen Wang, Pei-Chi Lo, Jia-You Fang, Shih-Chun Yang. Laser-assisted nanoparticle delivery to promote skin absorption and penetration depth of retinoic acid with the aim for treating photoaging. International journal of pharmaceutics. 2022 Nov; 627(?):122162. doi: 10.1016/j.ijpharm.2022.122162. [PMID: 36122617]
  • Fathima N Cassim Bawa, Raja Gopoju, Yanyong Xu, Shuwei Hu, Yingdong Zhu, Shaoru Chen, Kavita Jadhav, Yanqiao Zhang. Retinoic Acid Receptor Alpha (RARα) in Macrophages Protects from Diet-Induced Atherosclerosis in Mice. Cells. 2022 10; 11(20):. doi: 10.3390/cells11203186. [PMID: 36291054]
  • Fathima N Cassim Bawa, Yanyong Xu, Raja Gopoju, Noel-Marie Plonski, Amy Shiyab, Shuwei Hu, Shaoru Chen, Yingdong Zhu, Kavita Jadhav, Takhar Kasumov, Yanqiao Zhang. Hepatic retinoic acid receptor alpha mediates all-trans retinoic acid's effect on diet-induced hepatosteatosis. Hepatology communications. 2022 10; 6(10):2665-2675. doi: 10.1002/hep4.2049. [PMID: 35852305]
  • Rui-Ying Guo, Jing Xiang, Li-Jun Wang, Er-Chao Li, Ji-Liang Zhang. Tributyltin exposure disrupted the locomotor activity rhythms in adult zebrafish (Danio rerio) and the mechanism involved. Aquatic toxicology (Amsterdam, Netherlands). 2022 Oct; 251(?):106287. doi: 10.1016/j.aquatox.2022.106287. [PMID: 36067546]
  • Julia S Steinhoff, Carina Wagner, Ulrike Taschler, Sascha Wulff, Marie F Kiefer, Konstantin M Petricek, Sylvia J Wowro, Moritz Oster, Roberto E Flores, Na Yang, Chen Li, Yueming Meng, Manuela Sommerfeld, Stefan Weger, Andrea Henze, Jens Raila, Achim Lass, Michael Schupp. Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces fibroblast growth factor 21 expression. Journal of lipid research. 2022 10; 63(10):100268. doi: 10.1016/j.jlr.2022.100268. [PMID: 36030930]
  • Xiying Wu, Jingjing Xuan, Qin Yu, Wei Wu, Yi Lu, Quangang Zhu, Zhongjian Chen, Jianping Qi. Converting Tretinoin into Ionic Liquids for Improving Aqueous Solubility and Permeability across Skin. Pharmaceutical research. 2022 Oct; 39(10):2421-2430. doi: 10.1007/s11095-022-03238-6. [PMID: 35352282]
  • Ting Zhang, Shaokai Huang, Jingyi Qiu, Xuangao Wu, Heng Yuan, Sunmin Park. Beneficial Effect of Gastrodia elata Blume and Poria cocos Wolf Administration on Acute UVB Irradiation by Alleviating Inflammation through Promoting the Gut-Skin Axis. International journal of molecular sciences. 2022 Sep; 23(18):. doi: 10.3390/ijms231810833. [PMID: 36142744]
  • Xiaoxiao Yu, Yannan Ma, Yanhui Luo, Gaojian Tang, Zongyou Jiang, Jiashan Zhang, Boping Ye, Zhongzuo Huang, Yicheng Luo, Min Du, Bo Wang. Neonatal vitamin A administration increases intramuscular fat by promoting angiogenesis and preadipocyte formation. Meat science. 2022 Sep; 191(?):108847. doi: 10.1016/j.meatsci.2022.108847. [PMID: 35594692]
  • Chelsee Holloway, Guo Zhong, Youn-Kyung Kim, Hong Ye, Harini Sampath, Ulrich Hammerling, Nina Isoherranen, Loredana Quadro. Retinoic acid regulates pyruvate dehydrogenase kinase 4 (Pdk4) to modulate fuel utilization in the adult heart: Insights from wild-type and β-carotene 9',10' oxygenase knockout mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2022 09; 36(9):e22513. doi: 10.1096/fj.202101910rr. [PMID: 36004605]
  • Reza Karimi-Soflou, Akbar Karkhaneh, Iman Shabani. Size-adjustable self-assembled nanoparticles through microfluidic platform promotes neuronal differentiation of mouse embryonic stem cells. Biomaterials advances. 2022 Sep; 140(?):213056. doi: 10.1016/j.bioadv.2022.213056. [PMID: 35932661]
  • Aniseh Samadi, Zohre Sartipi, Saman Ahmad Nasrollahi, Behjat Sheikholeslami, Mansour Nassiri Kashani, Mohammad Reza Rouini, Rassoul Dinarvand, Alireza Firooz. Efficacy assessments of tretinoin-loaded nano lipid carriers in acne vulgaris: a double blind, split-face randomized clinical study. Archives of dermatological research. 2022 Aug; 314(6):553-561. doi: 10.1007/s00403-021-02256-5. [PMID: 34146120]
  • Esin Yalcınkaya, Mustafa Mert Basaran, Mehmet Emin Tunckasık, Gulce Naz Yazici, Çigdem Elmas, Sinan Kocaturk. Efficiency of hypericum perforatum, povidone iodine, tincture benzoin and tretinoin on wound healing. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022 Aug; 166(?):113209. doi: 10.1016/j.fct.2022.113209. [PMID: 35688269]
  • Ge-Ge Gong, Jie Zheng, Sha Li, Ya-Li Bai, Yu-Qi Feng. Triple chemical derivatization strategy assisted liquid chromatography-mass spectrometry for determination of retinoic acids in human serum. Talanta. 2022 Aug; 245(?):123474. doi: 10.1016/j.talanta.2022.123474. [PMID: 35462137]
  • Siqi Zhang, Yi Sui, Shuang Yan, Yifei Zhang, Chong Ding, Xiaodong Su, Jingwei Xiong, Shicheng Wei. Retinoic acid and FGF10 promote the differentiation of pluripotent stem cells into salivary gland placodes. Stem cell research & therapy. 2022 07; 13(1):368. doi: 10.1186/s13287-022-03033-5. [PMID: 35902913]
  • Lourdes Sainero-Alcolado, Muhammad Mushtaq, Judit Liaño-Pons, Aida Rodriguez-Garcia, Ye Yuan, Tong Liu, María Victoria Ruiz-Pérez, Susanne Schlisio, Oscar Bedoya-Reina, Marie Arsenian-Henriksson. Expression and activation of nuclear hormone receptors result in neuronal differentiation and favorable prognosis in neuroblastoma. Journal of experimental & clinical cancer research : CR. 2022 Jul; 41(1):226. doi: 10.1186/s13046-022-02399-x. [PMID: 35850708]
  • Liu-Hua Liao, Yi-Qiao Chen, Dan-Ping Huang, Li-Na Wang, Zhong-Lu Ye, Li-Hua Yang, Hui-Rong Mai, Yu Li, Cong Liang, Jie-Si Luo, Li-Na Wang, Xue-Qun Luo, Yan-Lai Tang, Xiao-Li Zhang, Li-Bin Huang. The comparison of plasma arsenic concentration and urinary arsenic excretion during treatment with Realgar-Indigo naturalis formula and arsenic trioxide in children with acute promyelocytic leukemia. Cancer chemotherapy and pharmacology. 2022 Jul; 90(1):45-52. doi: 10.1007/s00280-022-04449-9. [PMID: 35760920]
  • Mai Barakat, Abdelaziz M Hussein, Mohamed F Salama, Amira Awadalla, Nashwa Barakat, Mohamed Serria, Mohamed El-Shafey, Mohamed El-Sherbiny, Mohamed A El Adl. Possible Underlying Mechanisms for the Renoprotective Effect of Retinoic Acid-Pretreated Wharton's Jelly Mesenchymal Stem Cells against Renal Ischemia/Reperfusion Injury. Cells. 2022 06; 11(13):. doi: 10.3390/cells11131997. [PMID: 35805083]
  • Charbel Hanna, Monique Boily, Catherine Jumarie. Pesticides Inhibit Retinoic Acid Catabolism in PLHC-1 and ZFL Fish Hepatic Cell Lines. Chemical research in toxicology. 2022 06; 35(6):1045-1058. doi: 10.1021/acs.chemrestox.2c00050. [PMID: 35608517]
  • Xiang Qian, Hong-Yan Zhang, Qing-Lin Li, Guan-Jun Ma, Zhuo Chen, Xu-Ming Ji, Chang-Yu Li, Ai-Qin Zhang. Integrated microbiome, metabolome, and proteome analysis identifies a novel interplay among commensal bacteria, metabolites and candidate targets in non-small cell lung cancer. Clinical and translational medicine. 2022 06; 12(6):e947. doi: 10.1002/ctm2.947. [PMID: 35735103]
  • Zhen Yu, Xiaoyu Xie, Xiaonan Su, Huanran Lv, Shouyang Song, Chenxi Liu, Yajing You, Miaomiao Tian, Lihui Zhu, Le Wang, Jianni Qi, Qiang Zhu. ATRA-mediated-crosstalk between stellate cells and Kupffer cells inhibits autophagy and promotes NLRP3 activation in acute liver injury. Cellular signalling. 2022 05; 93(?):110304. doi: 10.1016/j.cellsig.2022.110304. [PMID: 35278669]
  • Yuan Wang, Wenyi Hou, Haitao Li, Xuanyu Tian, Jinqiao Li, Tianming Hu, Deli Shi, Yingmei Zhang. Analysis of risk factors for early death in patients with acute promyelocytic leukaemia treated with arsenic trioxide. Annals of hematology. 2022 May; 101(5):1039-1047. doi: 10.1007/s00277-022-04788-w. [PMID: 35174404]
  • Earl H Harrison. Carotenoids, β-Apocarotenoids, and Retinoids: The Long and the Short of It. Nutrients. 2022 Mar; 14(7):. doi: 10.3390/nu14071411. [PMID: 35406024]
  • Lindsay C Czuba, Emily E Fay, Jeffrey LaFrance, Chase K Smith, Sara Shum, Sue L Moreni, Jennie Mao, Nina Isoherranen, Mary F Hebert. Plasma Retinoid Concentrations Are Altered in Pregnant Women. Nutrients. 2022 Mar; 14(7):. doi: 10.3390/nu14071365. [PMID: 35405978]
  • Catherine O'Connor, Parisa Varshosaz, Alexander R Moise. Mechanisms of Feedback Regulation of Vitamin A Metabolism. Nutrients. 2022 Mar; 14(6):. doi: 10.3390/nu14061312. [PMID: 35334970]
  • Joo-Heon Park, Hyun-Woo Choi, Myung-Geun Shin. Coexistence of Acute Promyelocytic Leukemia and Primary Plasma Cell Leukemia: Careful Consideration in Diagnosis. Annals of laboratory medicine. 2022 03; 42(2):278-281. doi: 10.3343/alm.2022.42.2.278. [PMID: 34635620]
  • Jinhui Xu, Deli Zhang, Lin Feng, Yang Liu, Qingchun Diao. The efficacy and safety of topical Tretinoin combined with superficial X-ray therapy (SXRT) in treating periungual warts. Dermatologic therapy. 2022 03; 35(3):e15295. doi: 10.1111/dth.15295. [PMID: 34967065]
  • Cristina M Ghiuzeli, Miroslav Stýblo, Jesse Saunders, Anthony Calabro, Daniel Budman, Steven Allen, Craig Devoe, Radhika Dhingra. The pharmacokinetics of therapeutic arsenic trioxide in acute promyelocytic leukemia patients. Leukemia & lymphoma. 2022 03; 63(3):653-663. doi: 10.1080/10428194.2021.1978084. [PMID: 34689693]
  • Marta Melis, Xiao-Han Tang, Nabeel Attarwala, Qiuying Chen, Carlos Prishker, Lihui Qin, Steven S Gross, Lorraine J Gudas, Steven E Trasino. A retinoic acid receptor β2 agonist protects against alcohol liver disease and modulates hepatic expression of canonical retinoid metabolism genes. BioFactors (Oxford, England). 2022 Mar; 48(2):469-480. doi: 10.1002/biof.1794. [PMID: 34687254]
  • Gregory H Babunovic, Michael A DeJesus, Barbara Bosch, Michael R Chase, Thibault Barbier, Amy K Dickey, Bryan D Bryson, Jeremy M Rock, Sarah M Fortune. CRISPR Interference Reveals That All-Trans-Retinoic Acid Promotes Macrophage Control of Mycobacterium tuberculosis by Limiting Bacterial Access to Cholesterol and Propionyl Coenzyme A. mBio. 2022 02; 13(1):e0368321. doi: 10.1128/mbio.03683-21. [PMID: 35038923]
  • Maddalena Napolitano, Luca Potestio, Mario De Lucia, Mariateresa Nocerino, Gabriella Fabbrocini, Cataldo Patruno. Alitretinoin for the treatment of severe chronic eczema of the hands. Expert opinion on pharmacotherapy. 2022 Feb; 23(2):159-167. doi: 10.1080/14656566.2021.1998457. [PMID: 34789049]
  • Maurizio Gianni', Laura Goracci, Anna Schlaefli, Alessandra Di Veroli, Mami Kurosaki, Luca Guarrera, Marco Bolis, Marika Foglia, Monica Lupi, Mario P Tschan, Gabriele Cruciani, Mineko Terao, Enrico Garattini. Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia. Cell death & disease. 2022 01; 13(1):30. doi: 10.1038/s41419-021-04476-z. [PMID: 35013142]
  • Sung-Bae Kim, Rika Fujii, Ramasamy Paulmurugan. Quantitative Imaging of Retinoic Acid Activities in Living Mammalian Cells. Methods in molecular biology (Clifton, N.J.). 2022; 2525(?):111-122. doi: 10.1007/978-1-0716-2473-9_8. [PMID: 35836063]
  • Chen Wang, Didi Zhao, Xing Shu, Kexin Wang, Tingting Wang, Xiao Lin, Daoming Zhang, Tao Xia, Shiqing Qian, Min Tang, Wanshui Yang, Anla Hu, Qihong Zhao. Protective effects of all-trans retinoic acid against gastric premalignant lesions by repressing exosomal LncHOXA10-pyruvate carboxylase axis. Journal of cancer research and clinical oncology. 2022 Jan; 148(1):121-135. doi: 10.1007/s00432-021-03820-2. [PMID: 34632533]
  • ShaoFeng Wu, Jing Fang, Fang Yu, Fang Han, Jun Xiao. Clinical Study of Intravitreal Injection of Anti-VEGF Drugs Combined with Triamcinolone Acetonide in the Treatment of Coats Disease. Computational and mathematical methods in medicine. 2022; 2022(?):9911549. doi: 10.1155/2022/9911549. [PMID: 35756410]
  • Anjie Zheng, Fang Xie, Sanyuan Shi, Shounan Liu, Jinfeng Long, Yuhong Xu. Sustained Drug Release From Liposomes for the Remodeling of Systemic Immune Homeostasis and the Tumor Microenvironment. Frontiers in immunology. 2022; 13(?):829391. doi: 10.3389/fimmu.2022.829391. [PMID: 35493504]
  • Noriko Takahashi. Inhibitory Effects of Vitamin A and Its Derivatives on Cancer Cell Growth Not Mediated by Retinoic Acid Receptors. Biological & pharmaceutical bulletin. 2022; 45(9):1213-1224. doi: 10.1248/bpb.b22-00315. [PMID: 36047189]
  • Jianfeng Li, Silvia Garavaglia, Zhaofeng Ye, Andrea Moretti, Olga V Belyaeva, Alison Beiser, Md Ibrahim, Anna Wilk, Steve McClellan, Alla V Klyuyeva, Kelli R Goggans, Natalia Y Kedishvili, E Alan Salter, Andrzej Wierzbicki, Marie E Migaud, Steven J Mullett, Nathan A Yates, Carlos J Camacho, Menico Rizzi, Robert W Sobol. A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells. Communications biology. 2021 12; 4(1):1420. doi: 10.1038/s42003-021-02949-7. [PMID: 34934174]
  • Hacer Berna Afacan Ozturk, Murat Albayrak, Senem Maral, Merih Reis Aras, Fatma Yilmaz, Pınar Akyol, Mesut Tiglioglu, Umit Yavuz Malkan. Hypercalcemia associated with the interaction between all trans retinoic acid and posaconazole in an acute promyelocytic leukemia case. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners. 2021 Dec; 27(8):2027-2029. doi: 10.1177/10781552211007889. [PMID: 33847196]
  • Zhiqing Zhong, Hong-Yan Li, Hongzhen Zhong, Wenshan Lin, Shujun Lin, Tianbiao Zhou. All-trans retinoic acid regulating angiopoietins-1 and alleviating extracellular matrix accumulation in interstitial fibrosis rats. Renal failure. 2021 Dec; 43(1):658-663. doi: 10.1080/0886022x.2021.1910046. [PMID: 33820492]
  • Shuangxue Li, Yuansheng Lei, Jieyun Lei, Hui Li. All‑trans retinoic acid promotes macrophage phagocytosis and decreases inflammation via inhibiting CD14/TLR4 in acute lung injury. Molecular medicine reports. 2021 Dec; 24(6):. doi: 10.3892/mmr.2021.12508. [PMID: 34676874]
  • Yaqi Li, Cheng-Hsin Wei, J Kalina Hodges, Michael H Green, A Catharine Ross. Priming with Retinoic Acid, an Active Metabolite of Vitamin A, Increases Vitamin A Uptake in the Small Intestine of Neonatal Rats. Nutrients. 2021 Nov; 13(12):. doi: 10.3390/nu13124275. [PMID: 34959827]
  • Benjamin L Cline, Wen Jiang, Chaebin Lee, Zhengwei Cao, Xueyuan Yang, Shuyue Zhan, Harrison Chong, Tao Zhang, Zhaoguo Han, Xuedan Wu, Li Yao, Hui Wang, Weizhong Zhang, Zibo Li, Jin Xie. Potassium Iodide Nanoparticles Enhance Radiotherapy against Breast Cancer by Exploiting the Sodium-Iodide Symporter. ACS nano. 2021 Nov; 15(11):17401-17411. doi: 10.1021/acsnano.1c01435. [PMID: 34694109]
  • V M Berlin Grace, D David Wilson, R Anushya, Siddikuzzaman. Regulation of inflammation and COX-2 gene expression in benzo (a) pyrene induced lung carcinogenesis in mice by all trans retinoic acid (ATRA). Life sciences. 2021 Nov; 285(?):119967. doi: 10.1016/j.lfs.2021.119967. [PMID: 34543639]
  • Jana Slováčková, Josef Slavík, Pavel Kulich, Josef Večeřa, Ondrej Kováč, Hana Paculová, Nicol Straková, Radek Fedr, João Pedro Silva, Félix Carvalho, Miroslav Machala, Jiřina Procházková. Polychlorinated environmental toxicants affect sphingolipid metabolism during neurogenesis in vitro. Toxicology. 2021 11; 463(?):152986. doi: 10.1016/j.tox.2021.152986. [PMID: 34627992]
  • Yupeng Liu, Fangying Yu, Suhuan Dai, Tingting Meng, Yun Zhu, Guoxi Qiu, Lijuan Wen, Xueqing Zhou, Hong Yuan, Fuqiang Hu. All-Trans Retinoic Acid and Doxorubicin Delivery by Folic Acid Modified Polymeric Micelles for the Modulation of Pin1-Mediated DOX-Induced Breast Cancer Stemness and Metastasis. Molecular pharmaceutics. 2021 11; 18(11):3966-3978. doi: 10.1021/acs.molpharmaceut.1c00220. [PMID: 34579532]
  • Wenting Hong, Dongke Xu, Xiaowei Song, Baolin Niu, Ziyan Zhuang, Yiteng Lu, Xiaohong Lei, Runjun Ma, Chao Lu, Ning Sun, Yimin Mao, Xiaobo Li. Vitamin A and retinoic acid accelerate the attenuation of intestinal adaptability upon feeding induced by high-fat diet in mice. The Journal of nutritional biochemistry. 2021 11; 97(?):108803. doi: 10.1016/j.jnutbio.2021.108803. [PMID: 34147602]
  • Botheina Ghandour, Ghassan Dbaibo, Nadine Darwiche. The unfolding role of ceramide in coordinating retinoid-based cancer therapy. The Biochemical journal. 2021 10; 478(19):3621-3642. doi: 10.1042/bcj20210368. [PMID: 34648006]
  • Subir Kumar Juin, Sathnur Pushpakumar, Utpal Sen. GYY4137 Regulates Extracellular Matrix Turnover in the Diabetic Kidney by Modulating Retinoid X Receptor Signaling. Biomolecules. 2021 10; 11(10):. doi: 10.3390/biom11101477. [PMID: 34680110]
  • Huyong Zheng, Hui Jiang, Shaoyan Hu, Ning Liao, Diying Shen, Xin Tian, Guoping Hao, Runming Jin, Jianxin Li, Yongjun Fang, Xiuli Ju, Ansheng Liu, Ningling Wang, Xiaowen Zhai, Jiashi Zhu, Qun Hu, Limin Li, Wei Liu, Lirong Sun, Li Wang, Yunpeng Dai, Xiaoqin Feng, Fu Li, Hui Liang, Xinhui Luo, Mei Yan, Qingning Yin, Yan Chen, Yueqin Han, Lijun Qu, Yanling Tao, Hui Gao, Zhixu He, Limin Lin, Jixia Luo, Kaili Pan, Jingrong Zhang, Rong Zhang, Min Zhou, Yuanyuan Zhang, Linya Wang, Ruidong Zhang, Peifang Xiao, Yayun Ling, Xiaoxia Peng, Yaguang Peng, Tianyou Wang. Arsenic Combined With All-Trans Retinoic Acid for Pediatric Acute Promyelocytic Leukemia: Report From the CCLG-APL2016 Protocol Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2021 10; 39(28):3161-3170. doi: 10.1200/jco.20.03096. [PMID: 34077242]
  • Clarissa L M da Silva Bergmann, Daniela Pochmann, Julio Bergmann, Fernanda Brasil Bocca, Isabel Proença, Jessica Marinho, Alexandre Mello, Caroline Dani. The use of retinoic acid in association with microneedling in the treatment of epidermal melasma: efficacy and oxidative stress parameters. Archives of dermatological research. 2021 Oct; 313(8):695-704. doi: 10.1007/s00403-020-02140-8. [PMID: 32978675]
  • Jianshi Yu, Weiliang Huang, Tian Liu, Amy E Defnet, Stephanie Zalesak-Kravec, Ann M Farese, Thomas J MacVittie, Maureen A Kane. Effect of Radiation on the Essential Nutrient Homeostasis and Signaling of Retinoids in a Non-human Primate Model with Minimal Bone Marrow Sparing. Health physics. 2021 10; 121(4):406-418. doi: 10.1097/hp.0000000000001477. [PMID: 34546221]