L-3-Cyanoalanine (BioDeep_00000003218)
Secondary id: BioDeep_00001869204
natural product human metabolite PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C4H6N2O2 (114.0429)
中文名称: β-氰基-L-丙氨酸
谱图信息:
最多检出来源 Homo sapiens(blood) 24.55%
分子结构信息
SMILES: C(C#N)C(C(=O)O)N
InChI: InChI=1S/C4H6N2O2/c5-2-1-3(6)4(7)8/h3H,1,6H2,(H,7,8)/t3-/m0/s1
描述信息
3-cyano-l-alanine, also known as L-beta-cyanoalanine or 3-cyanoalanine, (D)-isomer, is a member of the class of compounds known as L-alpha-amino acids. L-alpha-amino acids are alpha amino acids which have the L-configuration of the alpha-carbon atom. 3-cyano-l-alanine is soluble (in water) and an extremely strong acidic compound (based on its pKa). 3-cyano-l-alanine can be found in a number of food items such as conch, abiyuch, rubus (blackberry, raspberry), and lemon thyme, which makes 3-cyano-l-alanine a potential biomarker for the consumption of these food products. 3-cyano-l-alanine exists in all living organisms, ranging from bacteria to humans.
L-3-Cyanoalanine, also known as L-beta-cyanoalanine, belongs to the class of organic compounds known as L-alpha-amino acids. These are alpha-amino acids which have the L-configuration of the alpha-carbon atom. L-3-Cyanoalanine is a very strong basic compound (based on its pKa). L-3-Cyanoalanine exists in all living organisms, ranging from bacteria to humans. Outside of the human body, L-3-cyanoalanine has been detected, but not quantified in, several different foods, such as summer savouries, orange bell peppers, red rices, mixed nuts, and green bell peppers. This could make L-3-cyanoalanine a potential biomarker for the consumption of these foods.
同义名列表
18 个代谢物同义名
(2S)-2-Amino-3-cyanopropionic acid; (2S)-2-Amino-3-cyanopropanoic acid; L-2-Amino-3-cyanopropanoic acid; L-2-Amino-3-cyanopropionic acid; 2-Amino-3-cyanopropanoic acid; 2-Amino-3-cyanopropionic acid; 3-Cyanoalanine, (L)-isomer; beta-Cyano-L-alanine; L-beta-Cyanoalanine; β-Cyano-L-alanine; 3-cyano-L-alanine; beta-Cyanoalanine; L-β-Cyanoalanine; L-b-Cyanoalanine; L-3-Cyanoalanine; 3-Cyanoalanine; β-Cyanoalanine; 3-Cyano-L-alanine
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:16934
- KEGG: C02512
- PubChem: 439742
- HMDB: HMDB0060245
- Metlin: METLIN3241
- ChEMBL: CHEMBL4172293
- MetaCyc: CPD-603
- KNApSAcK: C00001350
- foodb: FDB030412
- chemspider: 388802
- CAS: 6232-19-5
- MoNA: PS090401
- PMhub: MS000008507
- PubChem: 5522
- PDB-CCD: ZTK
- 3DMET: B01584
- NIKKAJI: J51.820D
- KNApSAcK: 16934
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Huoyong Jiang, Nengdang Jiang, Li Wang, Jingjing Guo, Kexin Chen, Yijun Dai. Characterization of nitrilases from Variovorax boronicumulans that functions in insecticide flonicamid degradation and β-cyano-L-alanine detoxification.
Journal of applied microbiology.
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Plant signaling & behavior.
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BMC plant biology.
2018 Oct; 18(1):251. doi:
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eLife.
2014 Apr; 3(?):e02365. doi:
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Molecular plant.
2014 Jan; 7(1):231-43. doi:
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