Vancomycin (BioDeep_00000002635)

 

Secondary id: BioDeep_00000422588

human metabolite blood metabolite Chemicals and Drugs


代谢物信息卡片


(1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-22-(carbamoylmethyl)-5,47-dichloro-2,18,32,35,37-pentahydroxy-19-[(2R)-4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2^{3,6}.2^{14,17}.1^{8,12}.1^{29,33}.0^{10,25}.0^{34,39}]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid

化学式: C66H75Cl2N9O24 (1447.4301770000002)
中文名称: 万古霉素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1C(C(CC(O1)OC2C(C(C(OC2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)C(C(C(=O)NC(C(=O)NC5C(=O)NC7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9O)O)C(NC(=O)C(C(C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)CC(=O)N)NC(=O)C(CC(C)C)NC)O)Cl)CO)O)O)(C)N)O
InChI: InChI=1S/C66H75Cl2N9O24/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95)

描述信息

Vancomycin is only found in individuals that have used or taken this drug. It is an antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. [PubChem]The bactericidal action of vancomycin results primarily from inhibition of cell-wall biosynthesis. Specifically, vancomycin prevents incorporation of N-acetylmuramic acid (NAM)- and N-acetylglucosamine (NAG)-peptide subunits from being incorporated into the peptidoglycan matrix; which forms the major structural component of Gram-positive cell walls. The large hydrophilic molecule is able to form hydrogen bond interactions with the terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. Normally this is a five-point interaction. This binding of vancomycin to the D-Ala-D-Ala prevents the incorporation of the NAM/NAG-peptide subunits into the peptidoglycan matrix. In addition, vancomycin alters bacterial-cell-membrane permeability and RNA synthesis. There is no cross-resistance between vancomycin and other antibiotics. Vancomycin is not active in vitro against gram-negative bacilli, mycobacteria, or fungi.
A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07A - Intestinal antiinfectives > A07AA - Antibiotics
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01X - Other antibacterials > J01XA - Glycopeptide antibacterials
S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AA - Antibiotics
C254 - Anti-Infective Agent > C258 - Antibiotic > C61101 - Glycopeptide Antibiotic
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
Vancomycin is an antibiotic for the treatment of bacterial infections.

同义名列表

55 个代谢物同义名

(1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-22-(carbamoylmethyl)-5,47-dichloro-2,18,32,35,37-pentahydroxy-19-[(2R)-4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2^{3,6}.2^{14,17}.1^{8,12}.1^{29,33}.0^{10,25}.0^{34,39}]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid; (1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-22-(carbamoylmethyl)-5,47-dichloro-2,18,32,35,37-pentahydroxy-19-[(2R)-4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2³,⁶.2¹⁴,¹⁷.1⁸,¹².1²⁹,³³.0¹⁰,²⁵.0³⁴,³⁹]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid; (1S,2R,18R,22S,25R,28R,40S)-22-(2-Amino-2-oxoethyl)-48-[2-O-(3-amino-2,3,6-trideoxy-3-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[(N-methyl-D-leucyl)amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid; (1S,2R,18R,22S,25R,28R,40S)-22-(2-Amino-2-oxoethyl)-48-[2-O-(3-amino-2,3,6-trideoxy-3-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[(N-methyl-D-leucyl)amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylate; (1S,2R,18R,22S,25R,28R,40S)-22-(2-Amino-2-oxoethyl)-48-[2-O-(3-amino-2,3,6-trideoxy-3-methyl-α-L-lyxo-hexopyranosyl)-β-D-glucopyranosyloxy]-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[(N-methyl-D-leucyl)amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid; (1S,2R,18R,22S,25R,28R,40S)-22-(2-Amino-2-oxoethyl)-48-[2-O-(3-amino-2,3,6-trideoxy-3-methyl-a-L-lyxo-hexopyranosyl)-b-D-glucopyranosyloxy]-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[(N-methyl-D-leucyl)amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid; (1S,2R,18R,22S,25R,28R,40S)-22-(2-Amino-2-oxoethyl)-48-[2-O-(3-amino-2,3,6-trideoxy-3-methyl-α-L-lyxo-hexopyranosyl)-β-D-glucopyranosyloxy]-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[(N-methyl-D-leucyl)amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylate; (1S,2R,18R,22S,25R,28R,40S)-22-(2-Amino-2-oxoethyl)-48-[2-O-(3-amino-2,3,6-trideoxy-3-methyl-a-L-lyxo-hexopyranosyl)-b-D-glucopyranosyloxy]-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[(N-methyl-D-leucyl)amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylate; (2.2Sp,3.5Sa,2.6Sp)-O(4.2),C(3.4):C(5.4),O(4.6):c(3.5),C(2.7)-tricyclo[N-methyl-D-leucyl-3-chloro-(R)-beta-hydroxy-D-tyrosyl-L-asparaginyl-D-2-(4-{[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl]oxy}phenyl)glycyl-D-2-(4-hydroxyphenyl)glycyl-3-chloro-(R)-beta-hydroxy-L-tyrosyl-L-2-(3,5-dihydroxyphenyl)glycine]; (2.2Sp,3.5Sa,2.6Sp)-O(4.2),C(3.4):C(5.4),O(4.6):c(3.5),C(2.7)-tricyclo[N-methyl-D-leucyl-3-chloro-(R)-b-hydroxy-D-tyrosyl-L-asparaginyl-D-2-(4-{[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-a-L-lyxo-hexopyranosyl)-b-D-glucopyranosyl]oxy}phenyl)glycyl-D-2-(4-hydroxyphenyl)glycyl-3-chloro-(R)-b-hydroxy-L-tyrosyl-L-2-(3,5-dihydroxyphenyl)glycine]; (2.2Sp,3.5Sa,2.6Sp)-O(4.2),C(3.4):C(5.4),O(4.6):c(3.5),C(2.7)-tricyclo[N-methyl-D-leucyl-3-chloro-(R)-β-hydroxy-D-tyrosyl-L-asparaginyl-D-2-(4-{[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-α-L-lyxo-hexopyranosyl)-β-D-glucopyranosyl]oxy}phenyl)glycyl-D-2-(4-hydroxyphenyl)glycyl-3-chloro-(R)-β-hydroxy-L-tyrosyl-L-2-(3,5-dihydroxyphenyl)glycine]; 4-Methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44; Cell pharm brand OF vancomycin hydrochloride; Ratiopharm brand OF vancomycin hydrochloride; Eli lilly brand OF vancomycin hydrochloride; Azupharma brand OF vancomycin hydrochloride; Combino brand OF vancomycin hydrochloride; Curasan brand OF vancomycin hydrochloride; Abbott brand OF vancomycin hydrochloride; Dakota brand OF vancomycin hydrochloride; Chiesi brand OF vancomycin hydrochloride; Norman brand OF vancomycin hydrochloride; Dista brand OF vancomycin hydrochloride; Lilly brand OF vancomycin hydrochloride; Vancomycin phosphate (1:2), decahydrate; Hexal brand OF vancomycin hydrochloride; MIP brand OF vancomycin hydrochloride; Vancomycin phosphate (1:2); Hydrochloride, vancomycin; Vancomycin Hydrochloride; Vancomicina combino phar; Vancomycin-ratiopharm; Sulfate, vancomycin; Vancomicina norman; Vancomicina abbott; Vancomycin sulfate; Vancomycine dakota; Vancomicina chiesi; Vancomycin hexal; Vancomycin lilly; Vanco azupharma; Vancomycin HCL; AB-vancomycin; Vancomycinum; Vancocin HCL; Vancomicina; SCHEMBL3178; Vancomycine; Vanco-saar; Vancomycin; Vancomicin; Vanco-cell; Diatracin; Vancocine; Vancocin



数据库引用编号

21 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Zhihui Liu, Meizi Zeng, Yuquan Xiao, Xiaohua Zhu, Meiling Liu, Ying Long, Haitao Li, Youyu Zhang, Shouzhuo Yao. Surface-mediated fluorescent sensor array for identification of gut microbiota and monitoring of colorectal cancer. Talanta. 2024 Jul; 274(?):126081. doi: 10.1016/j.talanta.2024.126081. [PMID: 38613947]
  • Julia Werner, Florian Umstätter, Tobias Hertlein, Eric Mühlberg, Barbro Beijer, Sabrina Wohlfart, Stefan Zimmermann, Uwe Haberkorn, Knut Ohlsen, Gert Fricker, Walter Mier, Philipp Uhl. Oral Delivery of the Vancomycin Derivative FU002 by a Surface-Modified Liposomal Nanocarrier. Advanced healthcare materials. 2024 Jun; 13(14):e2303654. doi: 10.1002/adhm.202303654. [PMID: 38387090]
  • Hai Bang Pan, Yan Cui, Zhi Hang Wu, Ying Meng, Tian Ming Wang, Qi Fu, Qian Chen, Quan Xin Chen, Bo Wang. Effect of Different Local Antibiotic Regimens on Prevention of Postoperative Infection in Clean Surgical Wounds: A Systematic Review and Network Meta-analysis. Advances in skin & wound care. 2024 Apr; 37(4):216-223. doi: 10.1097/asw.0000000000000094. [PMID: 38353666]
  • Liqiang Zhou, Shuxing Xing. A meta-analysis examining the impact of intrawound treatment on reducing deep surgical site infections during instrumented spine surgery. International wound journal. 2024 Apr; 21(4):e14554. doi: 10.1111/iwj.14554. [PMID: 38151914]
  • Jee Hoon Park, Rachel E Reviello, Patrick J Loll. Crystal structure of vancomycin bound to the resistance determinant D-alanine-D-serine. IUCrJ. 2024 Mar; ?(?):. doi: 10.1107/s2052252524000289. [PMID: 38277167]
  • Yuquan Xiao, Pei Cheng, Xiaohua Zhu, Maotian Xu, Meiling Liu, Haitao Li, Youyu Zhang, Shouzhuo Yao. Antimicrobial Agent Functional Gold Nanocluster-Mediated Multichannel Sensor Array for Bacteria Sensing. Langmuir : the ACS journal of surfaces and colloids. 2024 01; 40(4):2369-2376. doi: 10.1021/acs.langmuir.3c03612. [PMID: 38230676]
  • Atul Kumar Tiwari, Munesh Kumar Gupta, Hari Prakash Yadav, Roger J Narayan, Prem C Pandey. Aggregation-Resistant, Turn-On-Off Fluorometric Sensing of Glutathione and Nickel (II) Using Vancomycin-Conjugated Gold Nanoparticles. Biosensors. 2024 Jan; 14(1):. doi: 10.3390/bios14010049. [PMID: 38248426]
  • Jian Hu, Xinjun Han, Xiaoxue Ma, Xutao Chen, Zhenping Zhou, Peilan Peng, Zhao Yu, Yongzhi Hou, Peiru Han, Long Pang, Yali Yang, Jia Xu, Wenhui Wu. Comparative proteomic analysis of vancomycin-sensitive and vancomycin-intermediate resistant Staphylococcus aureus. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 2024 Jan; 43(1):139-153. doi: 10.1007/s10096-023-04709-3. [PMID: 37985551]
  • Rouba Yasser Al-Sroji, Shaza Al-Laham, Ahmad Almandili. Protective effects of vitamin D3 (cholecalciferol) on vancomycin-induced oxidative nephrotoxic damage in rats. Pharmaceutical biology. 2023 Dec; 61(1):755-766. doi: 10.1080/13880209.2023.2204916. [PMID: 37139624]
  • Mathias H Hansen, Martina Adamek, Dumitrita Iftime, Daniel Petras, Frauke Schuseil, Stephanie Grond, Evi Stegmann, Max J Cryle, Nadine Ziemert. Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nature communications. 2023 Nov; 14(1):7842. doi: 10.1038/s41467-023-43451-4. [PMID: 38030603]
  • Rouhallah Ramezanifard, Yekaterina A Golubeva, Alexander D Palmer, James M Slauch. TamAB is regulated by PhoPQ and functions in outer membrane homeostasis during Salmonella pathogenesis. Journal of bacteriology. 2023 10; 205(10):e0018323. doi: 10.1128/jb.00183-23. [PMID: 37728604]
  • Yunxiang Yan, Yong Liu, Juanjuan Li, Ye Li, Haoheng Wu, Hong Li, Xiang Ma, Yanqiong Tang, Yuan Tong, Kexian Yi, Quanfeng Liang, Zhu Liu. A Molecular Switch-Integrated Nanoplatform Enables Photo-Unlocked Antibacterial Drug Delivery for Synergistic Abscess Therapy. Advanced healthcare materials. 2023 10; 12(27):e2301157. doi: 10.1002/adhm.202301157. [PMID: 37392145]
  • Anaëlle Fait, Dan I Andersson, Hanne Ingmer. Evolutionary history of Staphylococcus aureus influences antibiotic resistance evolution. Current biology : CB. 2023 Jul; ?(?):. doi: 10.1016/j.cub.2023.06.082. [PMID: 37494936]
  • Zhenwei Yu, Jieqiong Liu, Haitao Yu, Ling Zhou, Yuhua Zhao, Lin Zhong, Jianping Zhu, Gang Liang, Yi Yang, Ying Zheng, Lingyan Yu, Gang Han. Should the trough concentration of vancomycin be abandoned in therapeutic drug monitoring? A multicentre, retrospective study of critically ill patients without any form of dialysis. International journal of antimicrobial agents. 2023 Jun; 61(6):106812. doi: 10.1016/j.ijantimicag.2023.106812. [PMID: 37037321]
  • Yong Lin, Liangbin Zhao, Dengpiao Xie, Lizeyu Lv, Yu Zhang, Ling Wu, Mingquan Li. Biopsy-proven granulomatous interstitial nephritis associated with vancomycin in an adult patient: a case report. The Journal of international medical research. 2023 Jun; 51(6):3000605231180052. doi: 10.1177/03000605231180052. [PMID: 37309693]
  • Gil Belofsky, Hyojin Ahn, Maxwell Zapata, Dominique Wilcox, Christine E Salomon, P Clint Spiegel. Antimicrobial Isoflavans and Other Metabolites of Dalea jamesii. Planta medica. 2023 Jun; 89(7):754-763. doi: 10.1055/a-2013-3008. [PMID: 36863394]
  • Mahir Mohammed, Usri H Ibrahim, Aimen Aljoundi, Calvin A Omolo, Nikita Devnarain, Mohammed A Gafar, Chunderika Mocktar, Thirumala Govender. Enzyme-responsive biomimetic solid lipid nanoparticles for antibiotic delivery against hyaluronidase-secreting bacteria. International journal of pharmaceutics. 2023 Apr; ?(?):122967. doi: 10.1016/j.ijpharm.2023.122967. [PMID: 37084831]
  • Santhni Subramaniam, Paul Joyce, Clive A Prestidge. Liquid crystalline lipid nanoparticles improve the antibacterial activity of tobramycin and vancomycin against intracellular Pseudomonas aeruginosa and Staphylococcus aureus. International journal of pharmaceutics. 2023 Apr; 639(?):122927. doi: 10.1016/j.ijpharm.2023.122927. [PMID: 37059243]
  • Alessandra Ottonello, Jessica A Wyllie, Oussama Yahiaoui, Shoujun Sun, Rebecca A Koelln, Joshua A Homer, Robert M Johnson, Ewan Murray, Paul Williams, Jani R Bolla, Carol V Robinson, Thomas Fallon, Tatiana P Soares da Costa, John E Moses. Shapeshifting bullvalene-linked vancomycin dimers as effective antibiotics against multidrug-resistant gram-positive bacteria. Proceedings of the National Academy of Sciences of the United States of America. 2023 Apr; 120(15):e2208737120. doi: 10.1073/pnas.2208737120. [PMID: 37011186]
  • Zhihui Liu, Xiaohua Zhu, Qiujun Lu, Meiling Liu, Haitao Li, Youyu Zhang, Yang Liu, Shouzhuo Yao. Recognition Engineering-Mediated Multichannel Sensor Array for Gut Microbiota Sensing. Analytical chemistry. 2023 Mar; ?(?):. doi: 10.1021/acs.analchem.2c04997. [PMID: 36975193]
  • Ashelyn E Sidders, Katarzyna M Kedziora, Melina Arts, Jan-Martin Daniel, Stefania de Benedetti, Jenna E Beam, Duyen T Bui, Joshua B Parsons, Tanja Schneider, Sarah E Rowe, Brian P Conlon. Antibiotic-induced accumulation of lipid II synergizes with antimicrobial fatty acids to eradicate bacterial populations. eLife. 2023 Mar; 12(?):. doi: 10.7554/elife.80246. [PMID: 36876902]
  • Kern Hast, M Rhia L Stone, Zhaojun Jia, Melih Baci, Tushar Aggarwal, Enver Cagri Izgu. Bioorthogonal Functionalization of Material Surfaces with Bioactive Molecules. ACS applied materials & interfaces. 2023 Feb; 15(4):4996-5009. doi: 10.1021/acsami.2c20942. [PMID: 36649474]
  • Mia Dželalija, Marija Kvesić, Anita Novak, Željana Fredotović, Hrvoje Kalinić, Ivica Šamanić, Marin Ordulj, Slaven Jozić, Ivana Goić Barišić, Marija Tonkić, Ana Maravić. Microbiome profiling and characterization of virulent and vancomycin-resistant Enterococcus faecium from treated and untreated wastewater, beach water and clinical sources. The Science of the total environment. 2023 Feb; 858(Pt 1):159720. doi: 10.1016/j.scitotenv.2022.159720. [PMID: 36306843]
  • Lingbing Zhang, Yandan Zhang, Xuejun Jiang, Lejiao Mao, Yinyin Xia, Yinzhen Fan, Na Li, Ziqi Jiang, Xia Qin, Yu Jiang, Gang Liu, Feng Qiu, Jun Zhang, Zhen Zou, Chengzhi Chen. Disruption of the lung-gut-brain axis is responsible for cortex damage induced by pulmonary exposure to zinc oxide nanoparticles. Toxicology. 2023 02; 485(?):153390. doi: 10.1016/j.tox.2022.153390. [PMID: 36535435]
  • Acharya Balkrishna, Sonam Sharma, Vivek Gohel, Ankita Kumari, Malini Rawat, Madhulina Maity, Sandeep Sinha, Rishabh Dev, Anurag Varshney. Renogrit attenuates Vancomycin-induced nephrotoxicity in human renal spheroids and in Sprague-Dawley rats by regulating kidney injury biomarkers and creatinine/urea clearance. PloS one. 2023; 18(11):e0293605. doi: 10.1371/journal.pone.0293605. [PMID: 37939153]
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