Tentoxin (BioDeep_00000002619)
代谢物信息卡片
Tentoxin
化学式: C22H30N4O4 (414.226694)
中文名称: 腾毒素
谱图信息:
最多检出来源 Mentha canadensis(plant) 94.44%
分子结构信息
SMILES: CC(C)CC1NC(=O)C(C)N(C)C(=O)CNC(=O)C(=Cc2ccccc2)N(C)C1=O
InChI: InChI=1S/C22H30N4O4/c1-14(2)11-17-22(30)26(5)18(12-16-9-7-6-8-10-16)21(29)23-13-19(27)25(4)15(3)20(28)24-17/h6-10,12,14-15,17H,11,13H2,1-5H3,(H,23,29)(H,24,28)/b18-12-/t15-,17-/m0/s1
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:9439
- KEGG: C08441
- PubChem: 5281143
- PubChem: 5398
- Metlin: METLIN66978
- KNApSAcK: C00001521
- CAS: 28540-82-1
- MoNA: AC000636
- MoNA: AC000635
- MoNA: AC000634
- MoNA: AC000633
- MoNA: AC000632
- PMhub: MS000004148
- PubChem: 10635
- PDB-CCD: TTX
- NIKKAJI: J34.249A
- RefMet: Tentoxin
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Nikola Puvača, Giuseppina Avantaggiato, Jordan Merkuri, Gorica Vuković, Vojislava Bursić, Magdalena Cara. Occurrence and Determination of Alternaria Mycotoxins Alternariol, Alternariol Monomethyl Ether, and Tentoxin in Wheat Grains by QuEChERS Method.
Toxins.
2022 11; 14(11):. doi:
10.3390/toxins14110791. [PMID: 36422965] - Xiaoting Qiao, Jing Zhang, Yunjia Yang, Jie Yin, Hong Li, Yang Xing, Bing Shao. Development of a simple and rapid LC-MS/MS method for the simultaneous quantification of five Alternaria mycotoxins in human urine.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2020 May; 1144(?):122096. doi:
10.1016/j.jchromb.2020.122096. [PMID: 32251989] - You-Hai Li, Wen-Jin Han, Xi-Wu Gui, Tao Wei, Shuang-Yan Tang, Jian-Ming Jin. Putative Nonribosomal Peptide Synthetase and Cytochrome P450 Genes Responsible for Tentoxin Biosynthesis in Alternaria alternata ZJ33.
Toxins.
2016 08; 8(8):. doi:
10.3390/toxins8080234. [PMID: 27490569] - Lieselotte De Bruyne, Christof Van Poucke, Diana Jose Di Mavungu, Nur Ain Izzati Mohd Zainudin, Lynn Vanhaecke, David De Vleesschauwer, B Gillian Turgeon, Sarah De Saeger, Monica Höfte. Comparative chemical screening and genetic analysis reveal tentoxin as a new virulence factor in Cochliobolus miyabeanus, the causal agent of brown spot disease on rice.
Molecular plant pathology.
2016 08; 17(6):805-17. doi:
10.1111/mpp.12329. [PMID: 26456797] - Panagiota Ntasiou, Charalampos Myresiotis, Sotiris Konstantinou, Euphemia Papadopoulou-Mourkidou, George S Karaoglanidis. Identification, characterization and mycotoxigenic ability of Alternaria spp. causing core rot of apple fruit in Greece.
International journal of food microbiology.
2015 Mar; 197(?):22-9. doi:
10.1016/j.ijfoodmicro.2014.12.008. [PMID: 25560914] - Ilenia Siciliano, Giuseppe Ortu, Giovanna Gilardi, Maria Lodovica Gullino, Angelo Garibaldi. Mycotoxin production in liquid culture and on plants infected with Alternaria spp. isolated from rocket and cabbage.
Toxins.
2015 Mar; 7(3):743-54. doi:
10.3390/toxins7030743. [PMID: 25751147] - Lan-Xin Shi, Steven M Theg. Energetic cost of protein import across the envelope membranes of chloroplasts.
Proceedings of the National Academy of Sciences of the United States of America.
2013 Jan; 110(3):930-5. doi:
10.1073/pnas.1115886110. [PMID: 23277572] - Erik Meiss, Hiroki Konno, Georg Groth, Toru Hisabori. Molecular processes of inhibition and stimulation of ATP synthase caused by the phytotoxin tentoxin.
The Journal of biological chemistry.
2008 Sep; 283(36):24594-9. doi:
10.1074/jbc.m802574200. [PMID: 18579520] - Claudia Schnick, Nicole Körtgen, Georg Groth. Complete inhibition of the tentoxin-resistant F1-ATPase from Escherichia coli by the phytopathogenic inhibitor tentoxin after substitution of critical residues in the alpha - and beta -subunit.
The Journal of biological chemistry.
2002 Dec; 277(52):51003-7. doi:
10.1074/jbc.m206095200. [PMID: 12399471] - Georg Groth, Toru Hisabori, Holger Lill, Dirk Bald. Substitution of a single amino acid switches the tentoxin-resistant thermophilic F1-ATPase into a tentoxin-sensitive enzyme.
The Journal of biological chemistry.
2002 Jun; 277(23):20117-9. doi:
10.1074/jbc.c200168200. [PMID: 11943766] - W C Tucker, Z Du, R Hein, Z Gromet-Elhanan, M L Richter. Role of the ATP synthase alpha-subunit in conferring sensitivity to tentoxin.
Biochemistry.
2001 Jun; 40(25):7542-8. doi:
10.1021/bi0105227. [PMID: 11412108] - W Yahyaoui, J Harnois, R Carpentier. Demonstration of thermal dissipation of absorbed quanta during energy-dependent quenching of chlorophyll fluorescence in photosynthetic membranes.
FEBS letters.
1998 Nov; 440(1-2):59-63. doi:
10.1016/s0014-5793(98)01430-6. [PMID: 9862425] - K Ramm, M Ramm, B Liebermann, G Reuter. Studies of the biosynthesis of tentoxin by Alternaria alternata.
Microbiology (Reading, England).
1994 Dec; 140 ( Pt 12)(?):3257-66. doi:
10.1099/13500872-140-12-3257. [PMID: 7881545] - G G Chen, A T Jagendorf. Chloroplast molecular chaperone-assisted refolding and reconstitution of an active multisubunit coupling factor CF1 core.
Proceedings of the National Academy of Sciences of the United States of America.
1994 Nov; 91(24):11497-501. doi:
10.1073/pnas.91.24.11497. [PMID: 7972091] - A Sommer, E Ne'eman, J C Steffens, A M Mayer, E Harel. Import, targeting, and processing of a plant polyphenol oxidase.
Plant physiology.
1994 Aug; 105(4):1301-11. doi:
10.1104/pp.105.4.1301. [PMID: 7972497] - A Avni, J D Anderson, N Holland, J D Rochaix, Z Gromet-Elhanan, M Edelman. Tentoxin sensitivity of chloroplasts determined by codon 83 of beta subunit of proton-ATPase.
Science (New York, N.Y.).
1992 Aug; 257(5074):1245-7. doi:
10.1126/science.1387730. [PMID: 1387730] - A Avni, M Edelman. Direct selection for paternal inheritance of chloroplasts in sexual progeny of Nicotiana.
Molecular & general genetics : MGG.
1991 Feb; 225(2):273-7. doi:
10.1007/bf00269859. [PMID: 2005869] - K Gwoździński, B Liebermann, I Dahse. Effects of tentoxin and dihydrotentoxin on human erythrocytes.
Cytobios.
1991; 67(270-271):183-91. doi:
. [PMID: 1666034] - E Van Volkenburgh, R E Cleland. Light-stimulated cell expansion in bean (Phaseolus vulgaris L.) leaves. I. Growth can occur without photosynthesis.
Planta.
1990 Aug; 182(1):72-6. doi:
10.1007/bf00239986. [PMID: 11538275] - F Heitz, F Kaddari, N Van Mau, J Verducci, H Raniri Seheno, R Lazaro. Ionic pores formed by cyclic peptides.
Biochimie.
1989 Jan; 71(1):71-6. doi:
10.1016/0300-9084(89)90134-x. [PMID: 2470418] - M G Klotz, E Müller, B Liebermann. Potassium transport through lipid bilayer membranes facilitated by tentoxin dimers. A new mechanism of ion carrier transport?.
Biophysical chemistry.
1987 Aug; 27(2):183-9. doi:
10.1016/0301-4622(87)80057-1. [PMID: 3663841] - F Heitz, R Jacquier, F Kaddari, J Verducci. Aggregation and ion transfer induced by tentoxin.
Biophysical chemistry.
1986 Mar; 23(3-4):245-9. doi:
10.1016/0301-4622(86)85010-4. [PMID: 3708101]