S-Ethyl dipropylthiocarbamate (BioDeep_00000002422)

 

Secondary id: BioDeep_00001871738

human metabolite blood metabolite


代谢物信息卡片


N,N-dipropyl(ethylsulfanyl)formamide

化学式: C9H19NOS (189.1187)
中文名称: 丙草丹, S-乙基二丙基硫代氨基甲酸酯
谱图信息: 最多检出来源 Homo sapiens(blood) 67.78%

分子结构信息

SMILES: CCCN(CCC)C(=O)SCC
InChI: InChI=1S/C9H19NOS/c1-4-7-10(8-5-2)9(11)12-6-3/h4-8H2,1-3H3



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 BRAF, MICA, PPP6C, TLR2
Peripheral membrane protein 2 ACHE, FDXR
Endosome membrane 1 LY96
Endoplasmic reticulum membrane 1 NRAS
Nucleus 5 ACHE, BRAF, CIPC, FOS, NEIL3
cytosol 5 BRAF, CIPC, FOS, NRAS, PPP6C
nucleoplasm 4 CIPC, FOS, NEIL3, PPP6C
RNA polymerase II transcription regulator complex 1 FOS
Cell membrane 4 ACHE, BRAF, MICA, NRAS
Lipid-anchor 1 NRAS
Cytoplasmic side 1 NRAS
Early endosome membrane 1 MICA
Golgi apparatus membrane 1 NRAS
Synapse 1 ACHE
cell surface 3 ACHE, MICA, TLR2
glutamatergic synapse 1 BRAF
Golgi apparatus 3 ACHE, NRAS, TLR2
Golgi membrane 1 NRAS
mitochondrial inner membrane 1 FDXR
neuromuscular junction 1 ACHE
postsynapse 1 BRAF
Cytoplasm, cytosol 1 CIPC
Lysosome 1 SGSH
Presynapse 1 BRAF
plasma membrane 6 ACHE, BRAF, LY96, MICA, NRAS, TLR2
Membrane 4 ACHE, MICA, NRAS, TLR2
extracellular exosome 3 ALDH2, NRAS, SGSH
endoplasmic reticulum 1 FOS
extracellular space 2 ACHE, MICA
lysosomal lumen 1 SGSH
perinuclear region of cytoplasm 1 ACHE
mitochondrion 4 ALDH2, BRAF, FDXR, PPP6C
intracellular membrane-bounded organelle 1 BRAF
Single-pass type I membrane protein 2 MICA, TLR2
Secreted 2 ACHE, LY96
extracellular region 2 ACHE, LY96
Single-pass membrane protein 1 MICA
Mitochondrion matrix 1 ALDH2
mitochondrial matrix 2 ALDH2, FDXR
Extracellular side 1 ACHE
external side of plasma membrane 1 MICA
nucleolus 1 CIPC
Mitochondrion inner membrane 1 FDXR
Membrane raft 1 TLR2
basement membrane 1 ACHE
receptor complex 2 LY96, TLR2
neuron projection 1 BRAF
chromatin 1 FOS
Cytoplasmic vesicle, phagosome membrane 1 TLR2
cell projection 1 TLR2
phagocytic vesicle membrane 2 MICA, TLR2
Chromosome 1 NEIL3
Secreted, extracellular space 1 LY96
Lipid-anchor, GPI-anchor 1 ACHE
Recycling endosome membrane 1 MICA
tertiary granule membrane 1 NRAS
cell body 2 BRAF, TLR2
side of membrane 1 ACHE
lipopolysaccharide receptor complex 1 LY96
secretory granule membrane 1 TLR2
nuclear matrix 1 FOS
ER to Golgi transport vesicle membrane 1 MICA
synaptic cleft 1 ACHE
protein-DNA complex 1 FOS
lumenal side of endoplasmic reticulum membrane 1 MICA
Toll-like receptor 1-Toll-like receptor 2 protein complex 1 TLR2
Toll-like receptor 2-Toll-like receptor 6 protein complex 1 TLR2
transcription factor AP-1 complex 1 FOS
[Isoform H]: Cell membrane 1 ACHE


文献列表

  • Jill Hochreiter, Elinore F McCance-Katz, Jill Lapham, Qing Ma, Gene D Morse. Disulfiram metabolite S-methyl-N,N-diethylthiocarbamate quantitation in human plasma with reverse phase ultra performance liquid chromatography and mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 May; 897(?):80-4. doi: 10.1016/j.jchromb.2012.03.035. [PMID: 22534656]
  • Gabriella Andreotti, Stella Koutros, Sonja I Berndt, Kathryn Hughes Barry, Lifang Hou, Jane A Hoppin, Dale P Sandler, Jay H Lubin, Laurie A Burdette, Jeffrey Yuenger, Meredith Yeager, Laura E Beane Freeman, Michael C R Alavanja. The Interaction between Pesticide Use and Genetic Variants Involved in Lipid Metabolism on Prostate Cancer Risk. Journal of cancer epidemiology. 2012; 2012(?):358076. doi: 10.1155/2012/358076. [PMID: 22919386]
  • María Elena Calderón-Segura, Sandra Gómez-Arroyo, Bertha Molina-Alvarez, Rafael Villalobos-Pietrini, Carmen Calderón-Ezquerro, Josefina Cortés-Eslava, Pedro Rafael Valencia-Quintana, Lucina López-González, Rubén Zúñiga-Reyes, José Sánchez-Rincón. Metabolic activation of herbicide products by Vicia faba detected in human peripheral lymphocytes using alkaline single cell gel electrophoresis. Toxicology in vitro : an international journal published in association with BIBRA. 2007 Sep; 21(6):1143-54. doi: 10.1016/j.tiv.2007.03.002. [PMID: 17482794]
  • C L Stiles, C E Sams, D K Robinson, D L Coffey, T C Mueller. Influence of metam sodium on the dissipation and residual biological activity of the herbicides EPTC and pebulate in surface soil under black plastic mulch. Journal of agricultural and food chemistry. 2000 Oct; 48(10):4681-6. doi: 10.1021/jf000564m. [PMID: 11052719]
  • B Bordás, T Kömíves, Z Szántó, A Lopata. Comparative three-dimensional quantitative structure-activity relationship study of safeners and herbicides. Journal of agricultural and food chemistry. 2000 Mar; 48(3):926-31. doi: 10.1021/jf990395+. [PMID: 10725176]
  • I Nagy, F Compernolle, K Ghys, J Vanderleyden, R De Mot. A single cytochrome P-450 system is involved in degradation of the herbicides EPTC (S-ethyl dipropylthiocarbamate) and atrazine by Rhodococcus sp. strain NI86/21. Applied and environmental microbiology. 1995 May; 61(5):2056-60. doi: 10.1128/aem.61.5.2056-2060.1995. [PMID: 7646049]
  • J R Cashman, L D Olsen, G Young, H Bern. S-oxygenation of eptam in hepatic microsomes from fresh- and saltwater striped bass (Morone saxatilis). Chemical research in toxicology. 1989 Nov; 2(6):392-9. doi: 10.1021/tx00012a007. [PMID: 2519729]
  • H Isaacs, J J Heffron, M Badenhorst. 'Picture frame' fibres in a carrier of the trait for malignant hyperpyrexia. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 1975 Nov; 49(46):1923-6. doi: NULL. [PMID: 795]