Isoproterenol (BioDeep_00000002297)

 

Secondary id: BioDeep_00001868059

human metabolite blood metabolite Chemicals and Drugs


代谢物信息卡片


4-(1-Hydroxy-2-((1-methylethyl)amino)ethyl)-1,2-benzenediol

化学式: C11H17NO3 (211.1208)
中文名称: 异丙肾上腺素, DL-异丙肾上腺素
谱图信息: 最多检出来源 Homo sapiens(blood) 37.61%

分子结构信息

SMILES: CC(C)NCC(C1=CC(=C(C=C1)O)O)O
InChI: InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3

描述信息

Isoproterenol is only found in individuals that have used or taken this drug. It is an isopropyl analog of epinephrine; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant. [PubChem]The pharmacologic effects of isoproterenol are at least in part attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic AMP. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.
R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03C - Adrenergics for systemic use > R03CB - Non-selective beta-adrenoreceptor agonists
R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03A - Adrenergics, inhalants > R03AB - Non-selective beta-adrenoreceptor agonists
C - Cardiovascular system > C01 - Cardiac therapy > C01C - Cardiac stimulants excl. cardiac glycosides > C01CA - Adrenergic and dopaminergic agents
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics
C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent > C319 - Bronchodilator
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D020011 - Protective Agents > D002316 - Cardiotonic Agents
D002317 - Cardiovascular Agents

同义名列表

46 个代谢物同义名

4-(1-Hydroxy-2-((1-methylethyl)amino)ethyl)-1,2-benzenediol; 3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol; 4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol; N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine; 3,4-Dihydroxy-a-[(isopropylamino)methyl]benzyl alcohol; 3,4-Dihydroxy-α-[(isopropylamino)methyl]benzyl alcohol; alpha-(Isopropylaminomethyl)protocatechuyl alcohol; N-Isopropyl-β-dihydroxyphenyl-β-hydroxyethylamine; N-Isopropyl-b-dihydroxyphenyl-b-hydroxyethylamine; 1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol; 1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol; Α-(isopropylaminomethyl)protocatechuyl alcohol; a-(Isopropylaminomethyl)protocatechuyl alcohol; Epinephrine isopropyl homolog; Hydrochloride, isoproterenol; Isoproterenol hydrochloride; N-Isopropylnorepinephrine; L-Isopropylnoradrenaline; N-Isopropylnoradrenaline; Noradrenaline, isopropyl; Isopropyl noradrenaline; Isopropylnorepinephrine; Isopropylnoradrenaline; Sulfate, isoproterenol; Isoproterenol chloride; Isoproterenol sulfate; Isopropyladrenaline; (+-)-Isoproterenol; Isopropylarterenol; (+-)-Isoprenaline; DL-Isoproterenol; L-Isoproterenol; Isoprenalinum; isoproterenol; Isoprenalina; Isoprenaline; Isopropydrin; Norisodrine; Isoprenalin; Isadrine; Novodrin; Euspiran; Isadrin; Izadrin; Isuprel; Isoproterenol



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 ACE, AXIN2, PPARG, PRKX
Endosome membrane 1 ADRB2
Endoplasmic reticulum membrane 1 PLN
Mitochondrion membrane 1 PLN
Nucleus 4 ADRB2, AXIN2, PPARG, PRKX
cytosol 5 AXIN2, LEP, PLIN1, PPARG, SST
dendrite 2 ADORA1, SLC8A1
mitochondrial membrane 1 PLN
centrosome 1 AXIN2
nucleoplasm 4 PPARG, PRKX, SCNN1G, SLC8A1
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 6 ACE, ADORA1, ADRB1, ADRB2, GPRC5A, SLC8A1
Multi-pass membrane protein 7 ADORA1, ADRB1, ADRB2, GPRC5A, RYR2, SCNN1G, SLC8A1
Synapse 3 ADORA1, SLC8A1, TAC1
cell junction 1 SLC8A1
Golgi apparatus 1 ADRB2
Golgi membrane 1 INS
neuronal cell body 4 ADORA1, SLC8A1, SST, TAC1
postsynapse 1 SLC8A1
presynaptic membrane 1 ADORA1
sarcolemma 2 RYR2, SLC8A1
smooth endoplasmic reticulum 1 RYR2
Lysosome 2 ACE, ADRB2
endosome 2 ACE, ADRB2
plasma membrane 10 ACE, ADORA1, ADRB1, ADRB2, AXIN2, GPRC5A, KNG1, RYR2, SCNN1G, SLC8A1
presynaptic active zone 1 ADORA1
terminal bouton 1 ADORA1
Membrane 6 ACE, ADRB2, PLIN1, PLN, RYR2, SLC8A1
apical plasma membrane 2 ADRB2, SCNN1G
axon 2 SLC8A1, TAC1
basolateral plasma membrane 1 ADORA1
extracellular exosome 4 ACE, GPRC5A, KNG1, SCNN1G
endoplasmic reticulum 2 PLIN1, PLN
extracellular space 7 ACE, INS, KNG1, LEP, PTH, SST, TAC1
perinuclear region of cytoplasm 2 PLN, PPARG
Schaffer collateral - CA1 synapse 1 ADRB1
intercalated disc 1 SLC8A1
mitochondrion 1 PLN
protein-containing complex 1 RYR2
intracellular membrane-bounded organelle 2 GPRC5A, PPARG
postsynaptic density 1 SLC8A1
Single-pass type I membrane protein 1 ACE
Secreted 5 ACE, INS, LEP, SST, VIP
extracellular region 8 ACE, INS, KNG1, LEP, PTH, SST, TAC1, VIP
Single-pass membrane protein 1 PLN
external side of plasma membrane 2 ACE, SCNN1G
dendritic spine 1 ADORA1
T-tubule 1 SLC8A1
Z disc 2 RYR2, SLC8A1
beta-catenin destruction complex 1 AXIN2
nucleolus 1 GPRC5A
Early endosome 2 ADRB1, ADRB2
vesicle 1 GPRC5A
postsynaptic membrane 1 ADORA1
Apical cell membrane 1 SCNN1G
axolemma 1 ADORA1
GABA-ergic synapse 1 SST
sarcoplasmic reticulum 2 PLN, RYR2
collagen-containing extracellular matrix 1 KNG1
receptor complex 3 ADRB2, GPRC5A, PPARG
neuron projection 1 VIP
chromatin 1 PPARG
cell periphery 1 SLC8A1
Secreted, extracellular space 1 KNG1
brush border membrane 1 ACE
blood microparticle 1 KNG1
sperm midpiece 1 ACE
endosome lumen 1 INS
Lipid droplet 1 PLIN1
Cytoplasmic vesicle membrane 1 GPRC5A
sodium channel complex 1 SCNN1G
basal plasma membrane 1 ACE
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 INS, KNG1
platelet alpha granule lumen 1 KNG1
axon terminus 1 SLC8A1
transport vesicle 1 INS
Sarcoplasmic reticulum membrane 2 PLN, RYR2
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
neuronal dense core vesicle 3 ADRB1, ADRB2, SST
calyx of Held 1 ADORA1
clathrin-coated endocytic vesicle membrane 1 ADRB2
calcium channel complex 1 RYR2
junctional sarcoplasmic reticulum membrane 1 RYR2
asymmetric synapse 1 ADORA1
[Angiotensin-converting enzyme, soluble form]: Secreted 1 ACE
[Isoform Testis-specific]: Cell membrane 1 ACE
calcium ion-transporting ATPase complex 1 PLN


文献列表

  • Linlin Liu, Mozhu Jin, Xueying Han, Deqiang Dou. Identifying biomarkers of ginseng medicines with different natures on heart failure. Journal of ethnopharmacology. 2024 Jul; 329(?):118134. doi: 10.1016/j.jep.2024.118134. [PMID: 38574777]
  • Julia G Odnoshivkina, Alexey M Petrov. 25-hydroxycholesterol triggers antioxidant signaling in mouse atria. Prostaglandins & other lipid mediators. 2024 Jun; 172(?):106834. doi: 10.1016/j.prostaglandins.2024.106834. [PMID: 38521490]
  • Jianfa Wu, Ying Cui, Weixing Ding, Jing Zhang, Lulu Wang. The protective effect of Macrostemonoside T from Allium macrostemon Bunge against Isoproterenol-Induced myocardial injury via the PI3K/Akt/mTOR signaling pathway. International immunopharmacology. 2024 May; 133(?):112086. doi: 10.1016/j.intimp.2024.112086. [PMID: 38642441]
  • Fu Peng, Minru Liao, Wenke Jin, Wei Liu, Zixiang Li, Zhichao Fan, Ling Zou, Siwei Chen, Lingjuan Zhu, Qian Zhao, Gu Zhan, Liang Ouyang, Cheng Peng, Bo Han, Jin Zhang, Leilei Fu. 2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis. Signal transduction and targeted therapy. 2024 May; 9(1):133. doi: 10.1038/s41392-024-01816-1. [PMID: 38744811]
  • Khushboo Bisht, Vipin Kumar Verma, Zia Abdullah, Vaishali Prajapati, Narang Rajiv, Jagriti Bhatia, Ruma Ray, Tapas Chandra Nag, Dharamvir Singh Arya. Arglabin: A mediator of inflammasome modulated and independent myocardial injury (PARA-AMI study). European journal of pharmacology. 2024 May; 970(?):176465. doi: 10.1016/j.ejphar.2024.176465. [PMID: 38479722]
  • Jincheng Jing, Shumei Fang, Yueting Li, Wenting Liu, Cong Wang, Yanyu Lan, Yonglin Wang, Chang Yang. An enhanced cardio-protective effect of nanoparticles loaded with active components from Polygonum orientale L. against isoproterenol-induced myocardial ischemia in rats. International journal of pharmaceutics. 2024 Apr; 655(?):124047. doi: 10.1016/j.ijpharm.2024.124047. [PMID: 38531434]
  • X Y Liao, P Liu, T F Luo, Y Li, Y Gao, F Y Pan, K C Wang. Punicalagin attenuates isoproterenol-induced myocardial infarction through nuclear factor erythroid 2-related factor 2/silent information regulator transcript-1-mediated inhibition of inflammation and cardiac stress markers in experimental animal models. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2024 Apr; 75(2):123-136. doi: 10.26402/jpp.2024.2.02. [PMID: 38736260]
  • Shweta Jaiswal, Md Meraj Anjum, Dilip Kumar Arya, Sunita Thakur, Prashant Pandey, Payal Deepak, Shubham Kanaujiya, Sneha Anand, Arjun Singh Kaushik, Vikas Mishra, Paruvathanahalli Siddalingam Rajinikanth. Surface entrenched β-sitosterol niosomes for enhanced cardioprotective activity against isoproterenol induced cardiotoxicity in rats. International journal of pharmaceutics. 2024 Mar; 653(?):123872. doi: 10.1016/j.ijpharm.2024.123872. [PMID: 38336178]
  • Shaoling Lin, Shengxi Zhang, Angyu Zhan, Jiaojiao Feng, Qianqian Yang, Tongjun Li, Zijian Liu, Quqian Mo, Hui Fan, Keke Wang, Lexun Wang. Palmatine alleviates cardiac fibrosis by inhibiting fibroblast activation through the STAT3 pathway. European journal of pharmacology. 2024 Mar; 967(?):176395. doi: 10.1016/j.ejphar.2024.176395. [PMID: 38350592]
  • Eve-Julie Tremblay, André Tchernof, Mélissa Pelletier, Denis R Joanisse, Pascale Mauriège. Plasma adiponectin/leptin ratio associates with subcutaneous abdominal and omental adipose tissue characteristics in women. BMC endocrine disorders. 2024 Mar; 24(1):39. doi: 10.1186/s12902-024-01567-8. [PMID: 38481206]
  • Xiao-Ting Zhang, Xu Zhang, Meng-Wei Wang, Chen Zhang, Rui Weng, Xu Xu, Zu-Xi Gu, Jian-Ping Gao. Multiple organs injury and myocardial energy metabolism disorders induced by isoproterenol. Toxicology. 2024 Mar; 503(?):153752. doi: 10.1016/j.tox.2024.153752. [PMID: 38369011]
  • Stanely Mainzen Prince Ponnian, Shervin Prince Stanely, Abhro Jyoti Roy. Cardioprotective effects of p-coumaric acid on tachycardia, inflammation, ion pump dysfunction, and electrolyte imbalance in isoproterenol-induced experimental myocardial infarction. Journal of biochemical and molecular toxicology. 2024 Mar; 38(3):e23668. doi: 10.1002/jbt.23668. [PMID: 38439645]
  • Bingmin Wu, Ruiyan Zheng, Minhua Ouyang, Yong Zhu, Huanjun Lu, Kaihao Liao, Yuhe Dong, Bolun Su, Junying Huang, Tian Zhong, Zhongqiu Liu, Jingyan Li. The water extract of Amydrium sinense (Engl.) H. Li ameliorates Isoproterenol-induced cardiac hypertrophy through inhibiting the NF-κB signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 Mar; 172(?):116241. doi: 10.1016/j.biopha.2024.116241. [PMID: 38330711]
  • Kai He, Xiaoying Wang, Tingting Li, Yanfei Li, Linlin Ma. Chlorogenic Acid Attenuates Isoproterenol Hydrochloride-Induced Cardiac Hypertrophy in AC16 Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway. Molecules (Basel, Switzerland). 2024 Feb; 29(4):. doi: 10.3390/molecules29040760. [PMID: 38398512]
  • Tanja Sobot, Zorislava Bajic, Ranko Skrbic, Snezana Uletilovic, Nebojsa Mandic-Kovacevic, Tanja Cvjetkovic, Ugljesa Malicevic, Djordje Djukanovic, Milica Gajic Bojic, Sanja Jovicic, Maja Barudzija, Milos P Stojiljkovic, Dragan M Djuric. Effect of folic acid on isoprenaline-induced myocardial injury in rats. Physiology international. 2024 Jan; ?(?):. doi: 10.1556/2060.2023.00291. [PMID: 38261080]
  • Huiling Luan, Zhenhui Wang, Zhenzhen Zhang, Baohua Hou, Zhenzhen Liu, Lanping Yang, Mengmeng Yang, Yile Ma, Baobao Zhang. Brassica oleracea L. extract ameliorates isoproterenol-induced myocardial injury by regulating HIF-1α-mediated glycolysis. Fitoterapia. 2024 Jan; 172(?):105715. doi: 10.1016/j.fitote.2023.105715. [PMID: 37907131]
  • Ziwei Xing, Chao Yang, Yaqian Feng, Junyao He, Cheng Peng, Dan Li. Understanding aconite's anti-fibrotic effects in cardiac fibrosis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jan; 122(?):155112. doi: 10.1016/j.phymed.2023.155112. [PMID: 37924690]
  • Shuai-Nan Zhang, Qi Liu, Xu-Zhao Li, Wu-De Yang, Ying Zhou. Sophora tonkinensis and active compounds inhibit mitochondrial impairments, inflammation, and LDLR deficiency in myocardial ischemia mice through regulating the vesicle-mediated transport pathway. Fitoterapia. 2024 Jan; 172(?):105756. doi: 10.1016/j.fitote.2023.105756. [PMID: 38007052]
  • Natalia V Belosludtseva, Lubov L Pavlik, Irina B Mikheeva, Eugeny Yu Talanov, Dmitriy A Serov, Dmitriy A Khurtin, Konstantin N Belosludtsev, Galina D Mironova. Protective Effect of Uridine on Structural and Functional Rearrangements in Heart Mitochondria after a High-Dose Isoprenaline Exposure Modelling Stress-Induced Cardiomyopathy in Rats. International journal of molecular sciences. 2023 Dec; 24(24):. doi: 10.3390/ijms242417300. [PMID: 38139129]
  • Xing-Yu Fan, Xiao-Qian Liao, Shu-Min Huang, Zi-Yi Wang, Lin Li, Zhi-Xi Hu. [Shenfu Injection improves chronic heart failure by regulating pyroptosis based on NLRP3/caspase-1 pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Dec; 48(23):6475-6482. doi: 10.19540/j.cnki.cjcmm.20230914.701. [PMID: 38212004]
  • Abhinav Rana, Thakur Uttam Singh, Meemansha Sharma, Manju Gari, Tarun Kumar, Subhashree Parida, Madhu Cholenahalli Lingaraju, Asok Kumar Mariappan, Akhilesh Kumar, Dinesh Kumar. Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model. Biotechnic & histochemistry : official publication of the Biological Stain Commission. 2023 Oct; ?(?):1-11. doi: 10.1080/10520295.2023.2260303. [PMID: 37814775]
  • Anita Yovas, Shervin Prince Stanely, Reya Issac, Stanely Mainzen Prince Ponnian. β-caryophyllene blocks reactive oxygen species-mediated hyperlipidemia in isoproterenol-induced myocardial infarcted rats. European journal of pharmacology. 2023 Oct; ?(?):176102. doi: 10.1016/j.ejphar.2023.176102. [PMID: 37827479]
  • Muthana M Jghef, Khadija Boukholda, Yassine Chtourou, Bernd L Fiebich, Mohammed Kebieche, Rachid Soulimani, Fatiha Chigr, Hamadi Fetoui. Punicalagin attenuates myocardial oxidative damage, inflammation, and apoptosis in isoproterenol-induced myocardial infarction in rats: Biochemical, immunohistochemical, and in silico molecular docking studies. Chemico-biological interactions. 2023 Oct; 385(?):110745. doi: 10.1016/j.cbi.2023.110745. [PMID: 37806379]
  • Lei Jiang, Tingchao Gao, Miao Liu, Fangxu Li. Chitosan-sodium alginate-polyethylene glycol-Ally isothiocyante nanocomposites ameliorates isoproterenol-induced myocardial infarction in rats. Journal of biochemical and molecular toxicology. 2023 Sep; ?(?):e23531. doi: 10.1002/jbt.23531. [PMID: 37724821]
  • Xuemei Zhang, Ying Zhao, Xin Zhao, Ji Zhang, Jiayu Diao, Shuo Jia, Panpan Feng, Penghua Yu, Gong Cheng. Anti-inflammatory, cardioprotective effect of gypenoside against isoproterenol-induced cardiac remodeling in rats via alteration of inflammation and gut microbiota. Inflammopharmacology. 2023 Aug; ?(?):. doi: 10.1007/s10787-023-01307-9. [PMID: 37603159]
  • Shereen S El-Mancy, Sylvia A Boshra, Osama S Elnahas, Sahar M Fayez, Nermin M Sheta. Enhancement of Bottle Gourd Oil Activity via Optimized Self-Dispersing Lipid Formulations (SDLFs) to Mitigate Isoproterenol-Evoked Cardiac Toxicity in Rats via Modulating BMP, MMP2, and miRNA-21 and miRNA-23a Genes' Expression. Molecules (Basel, Switzerland). 2023 Aug; 28(16):. doi: 10.3390/molecules28166168. [PMID: 37630419]
  • Jingyu Liao, Yuhao Zhang, Chi Ma, Gaosong Wu, Weidong Zhang. Microbiome-metabolome reveals that the Suxiao Jiuxin pill attenuates acute myocardial infarction associated with fatty acid metabolism. Journal of ethnopharmacology. 2023 Aug; 312(?):116529. doi: 10.1016/j.jep.2023.116529. [PMID: 37086873]
  • Huihui Wang, Baoping Xie, Shuotao Shi, Rong Zhang, Qi Liang, Zhongqiu Liu, Yuanyuan Cheng. Curdione inhibits ferroptosis in isoprenaline-induced myocardial infarction via regulating Keap1/Trx1/GPX4 signaling pathway. Phytotherapy research : PTR. 2023 Jul; ?(?):. doi: 10.1002/ptr.7964. [PMID: 37500597]
  • Yi Chen, Xiaoyun Guo, Yachang Zeng, Xiaoliang Mo, Siqi Hong, Hui He, Jing Li, Rachel Steinmetz, Qinghang Liu. Ferroptosis contributes to catecholamine-induced cardiotoxicity and pathological remodeling. Free radical biology & medicine. 2023 Jul; 207(?):227-238. doi: 10.1016/j.freeradbiomed.2023.07.025. [PMID: 37499888]
  • Yi-Hsin Chan, Feng-Chun Tsai, Gwo-Jyh Chang, Ying-Ju Lai, Shang-Hung Chang, Wei-Jan Chen, Yung-Hsin Yeh. CD44 regulates Epac1-mediated β-adrenergic-receptor-induced Ca2+-handling abnormalities: implication in cardiac arrhythmias. Journal of biomedical science. 2023 Jul; 30(1):55. doi: 10.1186/s12929-023-00944-0. [PMID: 37452346]
  • Anam Ali, Fatima Saqib. Ethnopharmacological basis and pharmacodynamics prospectives for folkloric claims of Rosa webbiana wall. Ex. Royle in diarrhea and asthma via In vitro, In vivo and In silico techniques. Journal of ethnopharmacology. 2023 Jun; 317(?):116696. doi: 10.1016/j.jep.2023.116696. [PMID: 37315649]
  • Miao Ye, Lingjie Ruan, Lina Huang, Haiyin Zheng, Wen Xu, Wei Xu, Lixia Chen, Hua Li. Triterpenoids with diverse skeletons from the roots of Rhus chinensis and their protective effects on isoproterenol-induced heart failure in zebrafish. Phytochemistry. 2023 Jun; 213(?):113749. doi: 10.1016/j.phytochem.2023.113749. [PMID: 37307886]
  • Anita Yovas, Shervin Prince Stanely, Stanely Mainzen Prince Ponnian. Protective effects of β-caryophyllene on mitochondrial damage and cardiac hypertrophy pathways in isoproterenol-induced myocardial infarcted rats. European journal of pharmacology. 2023 May; ?(?):175785. doi: 10.1016/j.ejphar.2023.175785. [PMID: 37207967]
  • Zijing Guo, Nan Zhang, Kexin Ma, Qinghua Lei, Guoping Ma, Baozhu Ding, Yi Zhong, Wenjie Liang, Nan Li. Establishment of a new arrhythmia model in SD rats induced by isoproterenol. Acta cardiologica. 2023 Apr; ?(?):1-10. doi: 10.1080/00015385.2023.2201726. [PMID: 37103119]
  • Meemansha Sharma, Thakur Uttam Singh, Abhinav Rana, Tarun Kumar, Manju Gari, Pashupathi Mani, Madhu Cholenahalli Lingaraju, Subhashree Parida, Vidya Singh, Monalisa Sahoo, Dinesh Kumar. Biochanin-A alleviates fibrosis and inflammation in cardiac injury in mice. Journal of biochemical and molecular toxicology. 2023 Apr; ?(?):e23360. doi: 10.1002/jbt.23360. [PMID: 37016276]
  • Doa'a G F Al-U'datt, Carole C Tranchant, Muhammad Alu'datt, Sara Abusara, Ahmed Al-Dwairi, Mohammad AlQudah, Othman Al-Shboul, Roddy Hiram, Yasemin Altuntas, Saied Jaradat, Karem H Alzoubi. Inhibition of transglutaminase 2 (TG2) ameliorates ventricular fibrosis in isoproterenol-induced heart failure in rats. Life sciences. 2023 Mar; 321(?):121564. doi: 10.1016/j.lfs.2023.121564. [PMID: 36931499]
  • Wei Wu, Qun Lu, Shan Ma, Jin-Chan Du, Kevin Huynh, Thy Duong, Zheng-Da Pang, Daniel Donner, Peter J Meikle, Xiu-Ling Deng, Xiao-Jun Du. Mitochondrial damage in a Takotsubo syndrome-like mouse model mediated by activation of b-adrenoceptor-Hippo signaling pathway. American journal of physiology. Heart and circulatory physiology. 2023 Mar; ?(?):. doi: 10.1152/ajpheart.00459.2022. [PMID: 36867446]
  • Xi Tao, Yaxin Xu, Joseph Adu-Amankwaah, Zheng Gong, Yuxuan Wang, Fei Huang, Hong Sun. β2AR against myocarditis-lipid deposition depends on estrogenic environment in stress. The Journal of endocrinology. 2023 Mar; 256(3):. doi: 10.1530/joe-22-0335. [PMID: 36633355]
  • Zorislava Bajic, Tanja Sobot, Snezana Uletilovic, Nebojsa Mandic-Kovacevic, Tanja Cvjetkovic, Ugljesa Malicevic, Đorđe Đukanović, Mladen Duran, Nikolina Vesic, Sanja Avram, Sanja Jovicic, Maja Katana, Amela Matavulj, Nenad Ponorac, Dragan Djuric, Milos P Stojiljkovic, Ranko Škrbic. CARDIOPROTECTIVE EFFECTS OF LIRAGLUTIDE PRETREATMENT ON ISOPRENALINE-INDUCED MYOCARDIAL INJURY IN RATS. Canadian journal of physiology and pharmacology. 2023 Feb; ?(?):. doi: 10.1139/cjpp-2022-0534. [PMID: 36848640]
  • Jian Xiong, Xiang Li, Hongjuan Fu, Xinye Luo, Xiao Li, Yanrong Ren, Xueying Liu, Qianhua Zheng, Wenchuan Qi, Fanrong Liang. Study on the specific expression of infrared radiation temperature on the body surface of acupoint in rats with chronic myocardial ischemic injury. Current medical imaging. 2023 Feb; ?(?):. doi: 10.2174/1573405619666230217120343. [PMID: 36799419]
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