Citalopram (BioDeep_00000229597)
Main id: BioDeep_00000397491
human metabolite
代谢物信息卡片
化学式: C20H21FN2O (324.1638)
中文名称: 西酞普兰
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
InChI: InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3
描述信息
N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants > N06AB - Selective serotonin reuptake inhibitors
D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017367 - Selective Serotonin Reuptake Inhibitors
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents
C78272 - Agent Affecting Nervous System > C94725 - Selective Serotonin Reuptake Inhibitor
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors
C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent
EAWAG_UCHEM_ID 2901; CONFIDENCE standard compound
CONFIDENCE standard compound; EAWAG_UCHEM_ID 2901
CONFIDENCE standard compound; INTERNAL_ID 8590
D049990 - Membrane Transport Modulators
同义名列表
2 个代谢物同义名
数据库引用编号
29 个数据库交叉引用编号
- ChEBI: CHEBI:77397
- ChEBI: CHEBI:3723
- KEGG: C07572
- KEGGdrug: D07704
- PubChem: 2771
- HMDB: HMDB05038
- DrugBank: DB00215
- ChEMBL: CHEMBL549
- MeSH: Citalopram
- CAS: 59729-33-8
- MoNA: EA290101
- MoNA: EA290107
- MoNA: SM859002
- MoNA: EA290113
- MoNA: EA290105
- MoNA: EA290112
- MoNA: EA290109
- MoNA: EA290114
- MoNA: EA290106
- MoNA: EA290111
- MoNA: EA290103
- MoNA: EA290104
- MoNA: EA290108
- MoNA: EA290110
- MoNA: EA290102
- PubChem: 9775
- NIKKAJI: J18.081E
- RefMet: Citalopram
- KNApSAcK: 3723
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Deniz Bozdag, Jeroen van Voorthuizen, Nikita Korpel, Sander Lentz, Hande Gurer-Orhan, Jorke H Kamstra. Dysregulation of adipogenesis and disrupted lipid metabolism by the antidepressants citalopram and sertraline.
Toxicology and applied pharmacology.
2024 May; 486(?):116937. doi:
10.1016/j.taap.2024.116937
. [PMID: 38643950] - Yeran Hwang, Ju-Tae Sohn. Effect of lipid emulsion on neuropsychiatric drug-induced toxicity: A narrative review.
Medicine.
2024 Mar; 103(11):e37612. doi:
10.1097/md.0000000000037612
. [PMID: 38489675] - Vanessa Fabienne Abegg, Miljenko Valentin Panajatovic, Riccardo Vincenzo Mancuso, Julien Arthur Allard, Urs Duthaler, Alex Odermatt, Stephan Krähenbühl, Jamal Bouitbir. Mechanisms of hepatocellular toxicity associated with the components of St. John's Wort extract hypericin and hyperforin in HepG2 and HepaRG cells.
Toxicology letters.
2024 Jan; 393(?):1-13. doi:
10.1016/j.toxlet.2024.01.008
. [PMID: 38219807] - Radka Kodešová, Helena Švecová, Aleš Klement, Miroslav Fér, Antonín Nikodem, Ganna Fedorova, Oleksandra Rieznyk, Martin Kočárek, Alina Sadchenko, Alica Chroňáková, Roman Grabic. Contamination of water, soil, and plants by micropollutants from reclaimed wastewater and sludge from a wastewater treatment plant.
The Science of the total environment.
2023 Oct; 907(?):167965. doi:
10.1016/j.scitotenv.2023.167965
. [PMID: 37866592] - Burcu Ersoy, Marie-Louise Herzog, Wen Pan, Simone Schilling, Matthias Endres, Ria Göttert, Golo D Kronenberg, Karen Gertz. The atypical antidepressant tianeptine confers neuroprotection against oxygen-glucose deprivation.
European archives of psychiatry and clinical neuroscience.
2023 Sep; ?(?):. doi:
10.1007/s00406-023-01685-9
. [PMID: 37653354] - Aaron L Nichols, Zack Blumenfeld, Laura Luebbert, Hailey J Knox, Anand K Muthusamy, Jonathan S Marvin, Charlene H Kim, Stephen N Grant, David P Walton, Bruce N Cohen, Rebekkah Hammar, Loren Looger, Per Artursson, Dennis A Dougherty, Henry A Lester. Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2023 03; 43(13):2222-2241. doi:
10.1523/jneurosci.1519-22.2022
. [PMID: 36868853] - Zhang-Jin Zhang, Shui-Yan Zhang, Xin-Jing Yang, Zong-Shi Qin, Feng-Quan Xu, Gui-Xing Jin, Xiao-Bing Hou, Yong Liu, Ji-Fu Cai, Hai-Bing Xiao, Yat Kwan Wong, Yu Zheng, Lei Shi, Jin-Niu Zhang, Yuan-Yuan Zhao, Xue Xiao, Liu-Lu Zhang, Yue Jiao, Yu Wang, Jia-Kai He, Guo-Bing Chen, Pei-Jing Rong. Transcutaneous electrical cranial-auricular acupoint stimulation versus escitalopram for mild-to-moderate depression: An assessor-blinded, randomized, non-inferiority trial.
Psychiatry and clinical neurosciences.
2023 Mar; 77(3):168-177. doi:
10.1111/pcn.13512
. [PMID: 36445151] - Tim Boogaerts, Maarten Quireyns, Hans De Loof, Xander Bertels, Natan Van Wichelen, Bram Pussig, Jan Saevels, Lies Lahousse, Pauline Bonmariage, Wouter Hamelinck, Bert Aertgeerts, Adrian Covaci, Alexander L N van Nuijs. Do the lockdown-imposed changes in a wastewater treatment plant catchment's socio-demographics impact longitudinal temporal trends in psychoactive pharmaceutical use?.
The Science of the total environment.
2023 Feb; ?(?):162342. doi:
10.1016/j.scitotenv.2023.162342
. [PMID: 36842581] - Vasiliki G Beretsou, Maria-Christina Nika, Kyriakos Manoli, Costas Michael, Qian Sui, Lian Lundy, D Michael Revitt, Nikolaos S Thomaidis, Despo Fatta-Kassinos. Multiclass target analysis of contaminants of emerging concern including transformation products, soil bioavailability assessment and retrospective screening as tools to evaluate risks associated with reclaimed water reuse.
The Science of the total environment.
2022 Dec; 852(?):158391. doi:
10.1016/j.scitotenv.2022.158391
. [PMID: 36049679] - Mariana N Miranda, Ana R Lado Ribeiro, Adrián M T Silva, M Fernando R Pereira. Can aged microplastics be transport vectors for organic micropollutants? - Sorption and phytotoxicity tests.
The Science of the total environment.
2022 Dec; 850(?):158073. doi:
10.1016/j.scitotenv.2022.158073
. [PMID: 35981591] - Somayeh Golbaz, Mirzaman Zamanzadeh, Kamyar Yaghmaeian, Ramin Nabizadeh, Nushin Rastkari, Hadi Esfahani. Occurrence and removal of psychiatric pharmaceuticals in the Tehran South Municipal Wastewater Treatment Plant.
Environmental science and pollution research international.
2022 Nov; ?(?):. doi:
10.1007/s11356-022-23667-5
. [PMID: 36374381] - Urwa Tariq, Masood Sadiq Butt, Imran Pasha, Muhammad Naeem Faisal. Prophylactic role of olive fruit extract against cigarette smoke-induced oxidative stress in Sprague-Dawley rats.
Cell stress & chaperones.
2022 09; 27(5):545-560. doi:
10.1007/s12192-022-01291-z
. [PMID: 35951259] - Hanyi Fang, Samantha Rossano, Xingxing Wang, Nabeel Nabulsi, Brian Kelley, Krista Fowles, Jim Ropchan, Stephen M Strittmatter, Richard E Carson, Yiyun Huang. Translational PET Imaging of Spinal Cord Injury with the Serotonin Transporter Tracer [11C]AFM.
Molecular imaging and biology.
2022 08; 24(4):560-569. doi:
10.1007/s11307-021-01698-7
. [PMID: 35020138] - Asmaa M Zaazaa, Nadia N Daoud, Ola A El-Gendy, Ahmad I Al-Shafei. Neuroprotective role of Bacopa monnieri extract in modulating depression in an experimental rat model.
Journal of affective disorders.
2022 07; 308(?):229-235. doi:
10.1016/j.jad.2022.04.021
. [PMID: 35413358] - M S Zastrozhin, VYu Skryabin, F Rwere, A E Petukhov, E P Pankratenko, S A Pozdniakov, V A Ivanchenko, V V Noskov, I A Zaytsev, N V Vinokurova, D S Horyaev, R V Vlasovskih, E A Bryun, D A Sychev. Influence of CYP2C19*17 Genetic Polymorphism on the Steady-State Concentration of Escitalopram in Patients with Recurrent Depressive Disorder.
Psychopharmacology bulletin.
2022 06; 52(3):8-19. doi:
NULL
. [PMID: 35815173] - Jesús E Yepez, Jorge Juárez. Modafinil acquires reinforcing effects when combined with citalopram.
Pharmacology, biochemistry, and behavior.
2022 06; 217(?):173407. doi:
10.1016/j.pbb.2022.173407
. [PMID: 35605783] - Nichol Ml Wong, Ottavia Dipasquale, Federico Turkheimer, James L Findon, Robert H Wichers, Mihail Dimitrov, Clodagh M Murphy, Vladimira Stoencheva, Dene M Robertson, Declan G Murphy, Eileen Daly, Grainne M McAlonan. Differences in social brain function in autism spectrum disorder are linked to the serotonin transporter: A randomised placebo-controlled single-dose crossover trial.
Journal of psychopharmacology (Oxford, England).
2022 06; 36(6):723-731. doi:
10.1177/02698811221092509
. [PMID: 35491679] - Magdalene M Assimon, Patrick H Pun, Sana M Al-Khatib, M Alan Brookhart, Bradley N Gaynes, Wolfgang C Winkelmayer, Jennifer E Flythe. Proton pump inhibitors may enhance the risk of citalopram- and escitalopram-associated sudden cardiac death among patients receiving hemodialysis.
Pharmacoepidemiology and drug safety.
2022 06; 31(6):670-679. doi:
10.1002/pds.5428
. [PMID: 35285107] - Ángel A Islas, Thomas Scior. Allosteric Binding of MDMA to the Human Serotonin Transporter (hSERT) via Ensemble Binding Space Analysis with ΔG Calculations, Induced Fit Docking and Monte Carlo Simulations.
Molecules (Basel, Switzerland).
2022 May; 27(9):. doi:
10.3390/molecules27092977
. [PMID: 35566327] - Rui Zhou, Shanshan Wang, Kunze Du, Ye Shang, Jun He, Jin Li, Yaqi Yao, Yan-Xu Chang. Stereoselective enrichment and determination of citalopram enantiomers by cation-selective exhaustive injection and sweeping coupled with cyclodextrin modified electrokinetic chromatography.
Journal of chromatography. A.
2022 Apr; 1669(?):462951. doi:
10.1016/j.chroma.2022.462951
. [PMID: 35303575] - Mohammad-Hadi Karimi-Harandi, Mehdi Shabani-Nooshabadi, Rozhin Darabi. Simultaneous determination of citalopram and selegiline using an efficient electrochemical sensor based on ZIF-8 decorated with RGO and g-C3N4 in real samples.
Analytica chimica acta.
2022 Apr; 1203(?):339662. doi:
10.1016/j.aca.2022.339662
. [PMID: 35361426] - Rachel G Zsido, Eóin N Molloy, Elena Cesnaite, Gergana Zheleva, Nathalie Beinhölzl, Ulrike Scharrer, Fabian A Piecha, Ralf Regenthal, Arno Villringer, Vadim V Nikulin, Julia Sacher. One-week escitalopram intake alters the excitation-inhibition balance in the healthy female brain.
Human brain mapping.
2022 04; 43(6):1868-1881. doi:
10.1002/hbm.25760
. [PMID: 35064716] - Shaoyuan Li, Peijing Rong, Yu Wang, Guixing Jin, Xiaobing Hou, Suxia Li, Xue Xiao, Wei Zhou, Yue Wu, Yaping Liu, Yue Zhang, Bin Zhao, Yiting Huang, Jin Cao, Helen Chen, Sierra Hodges, Mark Vangel, Jian Kong. Comparative Effectiveness of Transcutaneous Auricular Vagus Nerve Stimulation vs Citalopram for Major Depressive Disorder: A Randomized Trial.
Neuromodulation : journal of the International Neuromodulation Society.
2022 Apr; 25(3):450-460. doi:
10.1016/j.neurom.2021.10.021
. [PMID: 35088753] - Fei Duan, Man-Man Li, Wei-Xia Li, Jin-Fa Tang, Zhi-Wan Wang. [Serum metabolomics of chronic obstructive pulmonary disease with lung-Qi deficiency syndrome].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2022 Apr; 47(8):2251-2256. doi:
10.19540/j.cnki.cjcmm.20211203.501
. [PMID: 35531742] - Anna M Becker, Friederike Holze, Tanja Grandinetti, Aaron Klaiber, Vanja E Toedtli, Karolina E Kolaczynska, Urs Duthaler, Nimmy Varghese, Anne Eckert, Edna Grünblatt, Matthias E Liechti. Acute Effects of Psilocybin After Escitalopram or Placebo Pretreatment in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Subjects.
Clinical pharmacology and therapeutics.
2022 04; 111(4):886-895. doi:
10.1002/cpt.2487
. [PMID: 34743319] - Ralph Gradisch, Dániel Szöllősi, Marco Niello, Erika Lazzarin, Harald H Sitte, Thomas Stockner. Occlusion of the human serotonin transporter is mediated by serotonin-induced conformational changes in the bundle domain.
The Journal of biological chemistry.
2022 03; 298(3):101613. doi:
10.1016/j.jbc.2022.101613
. [PMID: 35065961] - Xiaokang Li, Jinwen Li, Yunyuan Huang, Qi Gong, Yan Fu, Yixiang Xu, Junyang Huang, Haolan You, Dong Zhang, Dan Zhang, Fei Mao, Jin Zhu, Huan Wang, Haiyan Zhang, Jian Li. The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression.
European journal of medicinal chemistry.
2022 Feb; 229(?):114045. doi:
10.1016/j.ejmech.2021.114045
. [PMID: 34922191] - Weiwei Xue, Tingting Fu, Shengzhe Deng, Fengyuan Yang, Jingyi Yang, Feng Zhu. Molecular Mechanism for the Allosteric Inhibition of the Human Serotonin Transporter by Antidepressant Escitalopram.
ACS chemical neuroscience.
2022 02; 13(3):340-351. doi:
10.1021/acschemneuro.1c00694
. [PMID: 35041375] - Anders Sørensen, Henricus G Ruhé, Klaus Munkholm. The relationship between dose and serotonin transporter occupancy of antidepressants-a systematic review.
Molecular psychiatry.
2022 01; 27(1):192-201. doi:
10.1038/s41380-021-01285-w
. [PMID: 34548628] - Chih-Wei Hsu, Wei-Ting Tseng, Liang-Jen Wang, Yao-Hsu Yang, Hung-Yu Kao, Pao-Yen Lin. Comparative effectiveness of antidepressants on geriatric depression: Real-world evidence from a population-based study.
Journal of affective disorders.
2022 01; 296(?):609-615. doi:
10.1016/j.jad.2021.10.009
. [PMID: 34655698] - Carlos Eduardo Miranda de Sousa, Noely Camila Tavares Cavalcanti Bedor, Giovana Damasceno Sousa, Guilherme Henrique Onório de Oliveira, Leila Bastos Leal, Danilo Cesar Galindo Bedor, Whocely Victor de Castro, Davi Pereira de Santana. Selective LC-MS/MS determination of citalopram enantiomers and application to a pharmacokinetic evaluation of generic and reference formulations.
Biomedical chromatography : BMC.
2022 Jan; 36(1):e5237. doi:
10.1002/bmc.5237
. [PMID: 34469601] - Thomas J F Angenoorth, Stevan Stankovic, Marco Niello, Marion Holy, Simon D Brandt, Harald H Sitte, Julian Maier. Interaction Profiles of Central Nervous System Active Drugs at Human Organic Cation Transporters 1-3 and Human Plasma Membrane Monoamine Transporter.
International journal of molecular sciences.
2021 Nov; 22(23):. doi:
10.3390/ijms222312995
. [PMID: 34884800] - Olof R Hjorth, Andreas Frick, Malin Gingnell, Johanna M Hoppe, Vanda Faria, Sara Hultberg, Iman Alaie, Kristoffer N T Månsson, Jörgen Rosén, Margareta Reis, Kurt Wahlstedt, My Jonasson, Mark Lubberink, Gunnar Antoni, Mats Fredrikson, Tomas Furmark. Expectancy effects on serotonin and dopamine transporters during SSRI treatment of social anxiety disorder: a randomized clinical trial.
Translational psychiatry.
2021 11; 11(1):559. doi:
10.1038/s41398-021-01682-3
. [PMID: 34732695] - Robert Suchting, Charles E Green, Constanza de Dios, Jessica Vincent, F Gerard Moeller, Scott D Lane, Joy M Schmitz. Citalopram for treatment of cocaine use disorder: A Bayesian drop-the-loser randomized clinical trial.
Drug and alcohol dependence.
2021 11; 228(?):109054. doi:
10.1016/j.drugalcdep.2021.109054
. [PMID: 34600245] - Tomiko Oskotsky, Ivana Maric, Alice Tang, Boris Oskotsky, Ronald J Wong, Nima Aghaeepour, Marina Sirota, David K Stevenson. Mortality Risk Among Patients With COVID-19 Prescribed Selective Serotonin Reuptake Inhibitor Antidepressants.
JAMA network open.
2021 11; 4(11):e2133090. doi:
10.1001/jamanetworkopen.2021.33090
. [PMID: 34779847] - Jeremiah B Joyce, Caroline W Grant, Duan Liu, Siamak MahmoudianDehkordi, Rima Kaddurah-Daouk, Michelle Skime, Joanna Biernacka, Mark A Frye, Taryn Mayes, Thomas Carmody, Paul E Croarkin, Liewei Wang, Richard Weinshilboum, William V Bobo, Madhukar H Trivedi, Arjun P Athreya. Multi-omics driven predictions of response to acute phase combination antidepressant therapy: a machine learning approach with cross-trial replication.
Translational psychiatry.
2021 10; 11(1):513. doi:
10.1038/s41398-021-01632-z
. [PMID: 34620827] - Lobna A Abdelwahab, Omneya O Galal, Sahar S Abd El-Rahman, Amany I El-Brairy, Mahmoud M Khattab, Aiman S El-Khatib. Targeting the Oxytocin System to Ameliorate Early Life Depressive-Like Behaviors in Maternally-Separated Rats.
Biological & pharmaceutical bulletin.
2021 Oct; 44(10):1445-1457. doi:
10.1248/bpb.b21-00247
. [PMID: 34349049] - Takashi Shiroyama, Kouji Fukuyama, Motohiro Okada. Distinct Effects of Escitalopram and Vortioxetine on Astroglial L-Glutamate Release Associated with Connexin43.
International journal of molecular sciences.
2021 Sep; 22(18):. doi:
10.3390/ijms221810013
. [PMID: 34576176] - Lyndsey L Anderson, Peter T Doohan, Lachlan Oldfield, Richard C Kevin, Jonathon C Arnold, Maximus Berger, G Paul Amminger, Iain S McGregor. Citalopram and Cannabidiol: In Vitro and In Vivo Evidence of Pharmacokinetic Interactions Relevant to the Treatment of Anxiety Disorders in Young People.
Journal of clinical psychopharmacology.
2021 Sep; 41(5):525-533. doi:
10.1097/jcp.0000000000001427
. [PMID: 34121064] - Line Skute Bråten, Tore Haslemo, Marin M Jukic, Maxim Ivanov, Magnus Ingelman-Sundberg, Espen Molden, Marianne Kristiansen Kringen. A Novel CYP2C-Haplotype Associated With Ultrarapid Metabolism of Escitalopram.
Clinical pharmacology and therapeutics.
2021 09; 110(3):786-793. doi:
10.1002/cpt.2233
. [PMID: 33759177] - Gwenn S Smith, Hiroto Kuwabara, Neda F Gould, Najilla Nassery, Alena Savonenko, Jin Hui Joo, Kristin L Bigos, Michael Kraut, James Brasic, Daniel P Holt, Andrew W Hall, William B Mathews, Robert F Dannals, Ayon Nandi, Clifford I Workman. Molecular imaging of the serotonin transporter availability and occupancy by antidepressant treatment in late-life depression.
Neuropharmacology.
2021 08; 194(?):108447. doi:
10.1016/j.neuropharm.2021.108447
. [PMID: 33450276] - Eóin N Molloy, Rachel G Zsido, Fabian A Piecha, Nathalie Beinhölzl, Ulrike Scharrer, Gergana Zheleva, Ralf Regenthal, Bernhard Sehm, Vadim V Nikulin, Harald E Möller, Arno Villringer, Julia Sacher, Karsten Mueller. Decreased thalamo-cortico connectivity during an implicit sequence motor learning task and 7 days escitalopram intake.
Scientific reports.
2021 07; 11(1):15060. doi:
10.1038/s41598-021-94009-7
. [PMID: 34301974] - Yang Shen, Xiao Yang, Gaofei Li, Jiayu Gao, Ying Liang. The change of gut microbiota in MDD patients under SSRIs treatment.
Scientific reports.
2021 07; 11(1):14918. doi:
10.1038/s41598-021-94481-1
. [PMID: 34290352] - Merve Sarıkaya, Halil Ibrahim Ulusoy, Ummugulsum Morgul, Songül Ulusoy, Angela Tartaglia, Erkan Yılmaz, Mustafa Soylak, Marcello Locatelli, Abuzar Kabir. Sensitive determination of Fluoxetine and Citalopram antidepressants in urine and wastewater samples by liquid chromatography coupled with photodiode array detector.
Journal of chromatography. A.
2021 Jul; 1648(?):462215. doi:
10.1016/j.chroma.2021.462215
. [PMID: 34000593] - Zhongxia Shen, Feng Wang, Lijun Cui, Lie Ren, Xiujuan Hong, Yonggui Yuan, Xinhua Shen. Higher baseline serum adiponectin predicts better treatment remission in patients with generalized anxiety disorder treated with escitalopram.
Annals of palliative medicine.
2021 07; 10(7):7634-7643. doi:
10.21037/apm-21-1542
. [PMID: 34353051] - Gao Tu, Tingting Fu, Fengyuan Yang, Jingyi Yang, Zhao Zhang, Xiaojun Yao, Weiwei Xue, Feng Zhu. Understanding the Polypharmacological Profiles of Triple Reuptake Inhibitors by Molecular Simulation.
ACS chemical neuroscience.
2021 06; 12(11):2013-2026. doi:
10.1021/acschemneuro.1c00127
. [PMID: 33977725] - Marina Sagud, Matea Nikolac Perkovic, Anja Dvojkovic, Nenad Jaksic, Bjanka Vuksan-Cusa, Maja Zivkovic, Zorana Kusevic, Alma Mihaljevic-Peles, Nela Pivac. Distinct association of plasma BDNF concentration and cognitive function in depressed patients treated with vortioxetine or escitalopram.
Psychopharmacology.
2021 Jun; 238(6):1575-1584. doi:
10.1007/s00213-021-05790-2
. [PMID: 33560444] - Pierre Baumann, Gilles Bertschy, Fritz Ramseier, Rico Nil. Plasma Concentrations and Cardiovascular Effects of Citalopram Enantiomers After Oral Versus Infusion Citalopram Therapy in Dextromethorphan-Mephenytoin-Phenotyped Patients With Major Depression.
Therapeutic drug monitoring.
2021 06; 43(3):436-442. doi:
10.1097/ftd.0000000000000824
. [PMID: 33060488] - Eóin N Molloy, Karsten Mueller, Nathalie Beinhölzl, Maria Blöchl, Fabian A Piecha, André Pampel, Christopher J Steele, Ulrike Scharrer, Gergana Zheleva, Ralf Regenthal, Bernhard Sehm, Vadim V Nikulin, Harald E Möller, Arno Villringer, Julia Sacher. Modulation of premotor cortex response to sequence motor learning during escitalopram intake.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2021 06; 41(6):1449-1462. doi:
10.1177/0271678x20965161
. [PMID: 33148103] - Jiajia Duan, Yu Huang, Xunmin Tan, Tingjia Chai, Jing Wu, Hanping Zhang, Yifan Li, Xi Hu, Peng Zheng, Ping Ji, Libo Zhao, Deyu Yang, Liang Fang, Jinlin Song, Peng Xie. Characterization of gut microbiome in mice model of depression with divergent response to escitalopram treatment.
Translational psychiatry.
2021 05; 11(1):303. doi:
10.1038/s41398-021-01428-1
. [PMID: 34016954] - Or Burstein, Noam Simon, Yaarit Simchon-Tenenbaum, Moshe Rehavi, Motty Franko, Alon Shamir, Ravid Doron. Moderation of the transgenerational transference of antenatal stress-induced anxiety.
Translational psychiatry.
2021 05; 11(1):268. doi:
10.1038/s41398-021-01383-x
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Pakistan journal of pharmaceutical sciences.
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