Cyanazine (BioDeep_00000002163)

   

human metabolite blood metabolite


代谢物信息卡片


2-{[4-chloro-6-(ethylimino)-1,6-dihydro-1,3,5-triazin-2-yl]amino}-2-methylpropanenitrile

化学式: C9H13ClN6 (240.08901680000002)
中文名称: 甲醇中氰草津溶液
谱图信息: 最多检出来源 Homo sapiens(blood) 34.69%

分子结构信息

SMILES: CCN=c1nc(Cl)nc(NC(C)(C)C#N)[nH]1
InChI: InChI=1S/C9H13ClN6/c1-4-12-7-13-6(10)14-8(15-7)16-9(2,3)5-11/h4H2,1-3H3,(H2,12,13,14,15,16)

描述信息

CONFIDENCE standard compound; INTERNAL_ID 46; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7787; ORIGINAL_PRECURSOR_SCAN_NO 7785
CONFIDENCE standard compound; INTERNAL_ID 46; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7685; ORIGINAL_PRECURSOR_SCAN_NO 7683
CONFIDENCE standard compound; INTERNAL_ID 46; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7749; ORIGINAL_PRECURSOR_SCAN_NO 7747
CONFIDENCE standard compound; INTERNAL_ID 46; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7714; ORIGINAL_PRECURSOR_SCAN_NO 7710
CONFIDENCE standard compound; INTERNAL_ID 46; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7777; ORIGINAL_PRECURSOR_SCAN_NO 7774
CONFIDENCE standard compound; INTERNAL_ID 46; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7731; ORIGINAL_PRECURSOR_SCAN_NO 7729
CONFIDENCE standard compound; EAWAG_UCHEM_ID 2759
D010575 - Pesticides > D006540 - Herbicides
D016573 - Agrochemicals

同义名列表

11 个代谢物同义名

2-{[4-chloro-6-(ethylimino)-1,6-dihydro-1,3,5-triazin-2-yl]amino}-2-methylpropanenitrile; 2-([4-Chloro-6-(ethylamino)-1,3,5-triazin-2-yl]amino)-2-methylpropanenitrile; 2-[[4-Chloro-6-(ethylamino)-S-triazin-2-yl]amino]-2-methylpropionitrile; 2-Chloro-4-(1-cyano-1-methylethylamino)-6-ethylamine-1,3,5-triazine; 2-Chloro-4-(1-cyano-1-methylethylamino)-6-ethylamino-1,3,5-triazine; 2-Chloro-4-(1-cyano-1-methylethylamino)-6-ethylamino-S-triazine; Bladex 80W; Cyanazine; Fortrol; Bladex; payze



数据库引用编号

33 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Gabriella Andreotti, Laura E Beane Freeman, Joseph J Shearer, Catherine C Lerro, Stella Koutros, Christine G Parks, Aaron Blair, Charles F Lynch, Jay H Lubin, Dale P Sandler, Jonathan N Hofmann. Occupational Pesticide Use and Risk of Renal Cell Carcinoma in the Agricultural Health Study. Environmental health perspectives. 2020 06; 128(6):67011. doi: 10.1289/ehp6334. [PMID: 32692250]
  • Hongzhe Tian, Xuesong Bai, Jing Xu. Simultaneous determination of simazine, cyanazine, and atrazine in honey samples by dispersive liquid-liquid microextraction combined with high-performance liquid chromatography. Journal of separation science. 2017 Oct; 40(19):3882-3888. doi: 10.1002/jssc.201700498. [PMID: 28759149]
  • Atlasi Daneshvar, Khadija Aboulfadl, Liza Viglino, Romain Broséus, Sébastien Sauvé, Anne-Sophie Madoux-Humery, Gesa A Weyhenmeyer, Michèle Prévost. Evaluating pharmaceuticals and caffeine as indicators of fecal contamination in drinking water sources of the Greater Montreal region. Chemosphere. 2012 Jun; 88(1):131-9. doi: 10.1016/j.chemosphere.2012.03.016. [PMID: 22475153]
  • James W Simpkins, James A Swenberg, Noel Weiss, David Brusick, J Charles Eldridge, James T Stevens, Robert J Handa, Russell C Hovey, Tony M Plant, Timothy P Pastoor, Charles B Breckenridge. Atrazine and breast cancer: a framework assessment of the toxicological and epidemiological evidence. Toxicological sciences : an official journal of the Society of Toxicology. 2011 Oct; 123(2):441-59. doi: 10.1093/toxsci/kfr176. [PMID: 21768606]
  • Stefan Tukaj, Joanna Bisewska, Katarzyna Roeske, Zbigniew Tukaj. Time- and dose-dependent induction of HSP70 in Lemna minor exposed to different environmental stressors. Bulletin of environmental contamination and toxicology. 2011 Sep; 87(3):226-30. doi: 10.1007/s00128-011-0339-3. [PMID: 21681399]
  • Carlos Alvarez-Moya, Mónica Reynoso Silva, Alma Rosa Villalobos Arámbula, Alfonso Islas Sandoval, Hugo Castañeda Vasquez, Rosa María González Montes. Evaluation of genetic damage induced by glyphosate isopropylamine salt using Tradescantia bioassays. Genetics and molecular biology. 2011 Jan; 34(1):127-30. doi: 10.1590/s1415-47572010005000108. [PMID: 21637555]
  • Walid D Fakhouri, Joseph L Nuñez, Frances Trail. Atrazine binds to the growth hormone-releasing hormone receptor and affects growth hormone gene expression. Environmental health perspectives. 2010 Oct; 118(10):1400-5. doi: 10.1289/ehp.0900738. [PMID: 20529762]
  • M Waria, S D Comfort, S Onanong, T Satapanajaru, H Boparai, C Harris, D D Snow, D A Cassada. Field-scale cleanup of atrazine and cyanazine contaminated soil with a combined chemical-biological approach. Journal of environmental quality. 2009 Sep; 38(5):1803-11. doi: 10.2134/jeq2008.0361. [PMID: 19643745]
  • Jenny R Lenkowski, J Michael Reed, Lisa Deininger, Kelly A McLaughlin. Perturbation of organogenesis by the herbicide atrazine in the amphibian Xenopus laevis. Environmental health perspectives. 2008 Feb; 116(2):223-30. doi: 10.1289/ehp.10742. [PMID: 18288322]
  • Randy Outward, Clyde E Sorenson, J R Bradley. Effects of vegetated field borders on arthropods in cotton fields in eastern North Carolina. Journal of insect science (Online). 2008; 8(?):9. doi: 10.1673/031.008.0901. [PMID: 20345293]
  • Laura Delgado-Moreno, Lourdes Sánchez-Moreno, Aránzazu Peña. Assessment of olive cake as soil amendment for the controlled release of triazine herbicides. The Science of the total environment. 2007 May; 378(1-2):119-23. doi: 10.1016/j.scitotenv.2007.01.023. [PMID: 17289120]
  • Jianyi Ma, Shufeng Wang, Pinwei Wang, Liangjin Ma, Xiling Chen, Ruifu Xu. Toxicity assessment of 40 herbicides to the green alga Raphidocelis subcapitata. Ecotoxicology and environmental safety. 2006 Mar; 63(3):456-62. doi: 10.1016/j.ecoenv.2004.12.001. [PMID: 16406601]
  • J N Perry, L G Firbank, G T Champion, S J Clark, M S Heard, M J May, C Hawes, G R Squire, P Rothery, I P Woiwod, J D Pidgeon. Ban on triazine herbicides likely to reduce but not negate relative benefits of GMHT maize cropping. Nature. 2004 Mar; 428(6980):313-6. doi: 10.1038/nature02374. [PMID: 15001990]
  • William L Patzoldt, Bradley S Dixon, Patrick J Tranel. Triazine resistance in Amaranthus tuberculatus (Moq) Sauer that is not site-of-action mediated. Pest management science. 2003 Oct; 59(10):1134-42. doi: 10.1002/ps.743. [PMID: 14561071]
  • Cynthia J Hines, James A Deddens, Cynthia A F Striley, Raymond E Biagini, Dale A Shoemaker, Kenneth K Brown, Barbara A Mackenzie, R Delon Hull. Biological monitoring for selected herbicide biomarkers in the urine of exposed custom applicators: application of mixed-effect models. The Annals of occupational hygiene. 2003 Aug; 47(6):503-17. doi: 10.1093/annhyg/meg067. [PMID: 12890659]
  • Robert A McKelvey, John P Wright, Joy L Honegger. A comparison of crop and non-crop plants as sensitive indicator species for regulatory testing. Pest management science. 2002 Dec; 58(12):1161-74. doi: 10.1002/ps.504. [PMID: 12476989]
  • T C Mueller, S A Senseman, K H Carson, A S Sciumbato. Stability and recovery of triazine and chloroacetamide herbicides from pH adjusted water samples by using empore solid-phase extraction disks and gas chromatography with ion trap mass spectrometry. Journal of AOAC International. 2001 Jul; 84(4):1070-3. doi: 10.1093/jaoac/84.4.1070. [PMID: 11501907]
  • S M Schraer, D R Shaw, M Boyette, R H Coupe, E M Thurman. Comparison of enzyme-linked immunosorbent assay and gas chromatography procedures for the detection of cyanazine and metolachlor in surface water samples. Journal of agricultural and food chemistry. 2000 Dec; 48(12):5881-6. doi: 10.1021/jf991130y. [PMID: 11312764]
  • M S Bogdanffy, J C O'Connor, J F Hansen, V Gaddamidi, C S Van Pelt, J W Green, J C Cook. Chronic toxicity and oncogenicity bioassay in rats with the chloro-s-triazine herbicide cyanazine. Journal of toxicology and environmental health. Part A. 2000 Aug; 60(8):567-86. doi: 10.1080/00984100050082102. [PMID: 10983523]
  • N Gebendinger, M Radosevich. Inhibition of atrazine degradation by cyanazine and exogenous nitrogen in bacterial isolate M91-3. Applied microbiology and biotechnology. 1999 Mar; 51(3):375-81. doi: 10.1007/s002530051405. [PMID: 10222586]
  • F Liu, W Mu, J Wang, J Yu. [Study on the analytical method of s-triazine herbicide residues in soil and maize]. Se pu = Chinese journal of chromatography. 1998 Nov; 16(6):543-4. doi: . [PMID: 11938923]
  • G S Rodrigues, D Pimentel, L H Weinstein. In situ assessment of pesticide genotoxicity in an integrated pest management program I--Tradescantia micronucleus assay. Mutation research. 1998 Feb; 412(3):235-44. doi: 10.1016/s1383-5718(97)00193-9. [PMID: 9600691]
  • G S Rodrigues, D Pimentel, L H Weinstein. In situ assessment of pesticide genotoxicity in an integrated pest management program: II. Maize waxy mutation assay. Mutation research. 1998 Feb; 412(3):245-50. doi: 10.1016/s1383-5718(97)00194-0. [PMID: 9600692]
  • C Guigas, B L Pool-Zobel, J F Diehl. [The combination effects of quercetin with the herbicides atrazine, cyanazine and gesamprim in mutagenicity tests]. Zeitschrift fur Ernahrungswissenschaft. 1993 Jun; 32(2):131-8. doi: 10.1007/bf01614756. [PMID: 8379213]
  • J C Means, M J Plewa, J M Gentile. Assessment of the mutagenicity of fractions from s-triazine-treated Zea mays. Mutation research. 1988 Feb; 197(2):325-36. doi: 10.1016/0027-5107(88)90102-9. [PMID: 3123924]
  • A Pertzelan, R Keret, B Bauman, Z Josefsberg, Z Ben-Zeev, B Szoke, A M Comaru-Schally, A V Schally, Z Laron. Responsiveness of pituitary hGH to GRH1-44 in juveniles with obesity. Acta endocrinologica. 1986 Feb; 111(2):151-3. doi: 10.1530/acta.0.1110151. [PMID: 3082093]
  • M Sano. Subcellular localizations of guanylate cyclase and 3',5'-cyclic nucleotide phosphodiesterase in sea urchin sperm. Biochimica et biophysica acta. 1976 Apr; 428(2):525-31. doi: 10.1016/0304-4165(76)90061-1. [PMID: 6049]