Allidochlor (BioDeep_00000001886)

 

Secondary id: BioDeep_00001868106

human metabolite blood metabolite


代谢物信息卡片


2-chloro-N,N-bis(prop-2-en-1-yl)acetamide

化学式: C8H12ClNO (173.0607)
中文名称: 草毒死
谱图信息: 最多检出来源 Homo sapiens(blood) 99.57%

分子结构信息

SMILES: C=CCN(CC=C)C(=O)CCl
InChI: InChI=1S/C8H12ClNO/c1-3-5-10(6-4-2)8(11)7-9/h3-4H,1-2,5-7H2



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ALB, APOB, CAT, G6PD, VEGFA
Peripheral membrane protein 1 G6PD
Endosome membrane 1 APOB
Endoplasmic reticulum membrane 1 APOB
Nucleus 2 ALB, VEGFA
cytosol 5 ALB, APOB, CAT, G6PD, GSR
centrosome 1 ALB
Cell membrane 1 TNF
cell surface 3 ADIPOQ, TNF, VEGFA
Golgi apparatus 2 ALB, VEGFA
Golgi membrane 1 INS
lysosomal membrane 1 EGF
neuronal cell body 2 APOB, TNF
smooth endoplasmic reticulum 1 APOB
Cytoplasm, cytosol 1 G6PD
plasma membrane 4 APOB, EGF, IFNLR1, TNF
Membrane 5 CAT, EGF, G6PD, IFNLR1, VEGFA
extracellular exosome 7 ALB, APOB, CAT, EGF, G6PD, GSR, RETN
endoplasmic reticulum 3 ADIPOQ, ALB, VEGFA
extracellular space 16 ADIPOQ, ALB, APOB, CCL2, CRP, CXCL8, EGF, IL10, IL2, IL4, IL6, INS, LPA, RETN, TNF, VEGFA
lysosomal lumen 1 APOB
adherens junction 1 VEGFA
mitochondrion 2 CAT, GSR
protein-containing complex 2 ALB, CAT
intracellular membrane-bounded organelle 3 APOB, CAT, G6PD
Single-pass type I membrane protein 1 IFNLR1
Secreted 13 ADIPOQ, ALB, APOB, CCL2, CRP, CXCL8, IL10, IL2, IL4, IL6, INS, RETN, VEGFA
extracellular region 17 ADIPOQ, ALB, APOB, CAT, CCL2, CRP, CXCL8, EGF, IL10, IL2, IL4, IL6, INS, LPA, RETN, TNF, VEGFA
cytoplasmic side of plasma membrane 1 G6PD
mitochondrial matrix 2 CAT, GSR
anchoring junction 1 ALB
centriolar satellite 1 G6PD
external side of plasma membrane 2 GSR, TNF
Secreted, extracellular space, extracellular matrix 1 VEGFA
chylomicron 1 APOB
low-density lipoprotein particle 1 APOB
very-low-density lipoprotein particle 1 APOB
Early endosome 1 APOB
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 1 TNF
focal adhesion 1 CAT
extracellular matrix 1 VEGFA
Peroxisome 1 CAT
collagen trimer 1 ADIPOQ
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 ADIPOQ
secretory granule 1 VEGFA
ciliary basal body 1 ALB
phagocytic cup 1 TNF
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
endosome lumen 2 APOB, INS
Lipid droplet 1 APOB
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 ALB, APOB, IL6, INS
platelet alpha granule lumen 3 ALB, EGF, VEGFA
specific granule lumen 1 RETN
transport vesicle 1 INS
azurophil granule lumen 1 RETN
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
endoplasmic reticulum exit site 1 APOB
clathrin-coated endocytic vesicle membrane 2 APOB, EGF
endocytic vesicle lumen 1 APOB
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
chylomicron remnant 1 APOB
intermediate-density lipoprotein particle 1 APOB
catalase complex 1 CAT
mature chylomicron 1 APOB
interleukin-6 receptor complex 1 IL6
plasma lipoprotein particle 1 LPA
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
ciliary transition fiber 1 ALB
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Jing Xiao, Huanyu Xiang, Hongyan Xiang, Zilin Sun, Jing Xu, Hong Ren, Peng Hu, Mingli Peng. GW9662 ameliorates nonalcoholic steatohepatitis by inhibiting the PPARγ/CD36 pathway and altering the gut microbiota. European journal of pharmacology. 2023 Oct; ?(?):176113. doi: 10.1016/j.ejphar.2023.176113. [PMID: 37838102]
  • Davide Gnocchi, Marta B Afonso, Maria Maddalena Cavalluzzi, Giovanni Lentini, Giuseppe Ingravallo, Carlo Sabbà, Cecilia M P Rodrigues, Antonio Mazzocca. Inhibition of lysophosphatidic acid receptor 6 upregulated by the choline-deficient l-amino acid-defined diet prevents hepatocarcinogenesis in mice. Molecular carcinogenesis. 2023 Feb; ?(?):. doi: 10.1002/mc.23516. [PMID: 36752344]
  • Noriko Suzuki-Kemuriyama, Akari Abe, Sae Nakane, Megumi Yuki, Katsuhiro Miyajima, Dai Nakae. Nonalcoholic steatohepatitis-associated hepatocarcinogenesis in mice fed a modified choline-deficient, methionine-lowered, L-amino acid-defined diet and the role of signal changes. PloS one. 2023; 18(8):e0287657. doi: 10.1371/journal.pone.0287657. [PMID: 37535625]
  • Jian Ding, Ming Xu, Wei Du, Zhi-Qiang Fang, Hao Xu, Jing-Jing Liu, Ping Song, Chen Xu, Zhi-Wen Li, Zhen-Sheng Yue, Yu-Wei Ling, Juan-Li Duan, Kai-Shan Tao, Fei He, Lin Wang. Myeloid-specific blockade of Notch signaling ameliorates nonalcoholic fatty liver disease in mice. International journal of biological sciences. 2023; 19(6):1941-1954. doi: 10.7150/ijbs.80122. [PMID: 37063432]
  • Marta B Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F Simões, José Teixeira, Liana C Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E Castro, Paulo J Oliveira, Carina Prip-Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M P Rodrigues. RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Hepatology (Baltimore, Md.). 2022 Aug; ?(?):. doi: 10.1002/hep.32756. [PMID: 36029129]
  • B Bordás, T Kömíves, Z Szántó, A Lopata. Comparative three-dimensional quantitative structure-activity relationship study of safeners and herbicides. Journal of agricultural and food chemistry. 2000 Mar; 48(3):926-31. doi: 10.1021/jf990395+. [PMID: 10725176]