Diisooctyl phthalate (BioDeep_00001873894)

   


代谢物信息卡片


Diisooctyl phthalate

化学式: C24H38O4 (390.277)
中文名称: 邻苯二甲酸二异辛酯, 双邻苯二甲酸-6-甲基庚酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)CCCCCOC(=O)C1=CC=CC=C1C(=O)OCCCCCC(C)C
InChI: InChI=1S/C24H38O4/c1-19(2)13-7-5-11-17-27-23(25)21-15-9-10-16-22(21)24(26)28-18-12-6-8-14-20(3)4/h9-10,15-16,19-20H,5-8,11-14,17-18H2,1-4H3

描述信息

同义名列表

3 个代谢物同义名

Diisooctyl phthalate; Diisooctyl phthalate; Diisooctyl phthalate



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 CES1, CES2, ELANE, MAP4K4, MX2, PGR, PIK3CA, PTGS2, RUNX2, TGFB1, TLR4
Peripheral membrane protein 2 CYP27A1, PTGS2
Endosome membrane 1 TLR4
Endoplasmic reticulum membrane 3 HACD1, PTGS2, SPP1
Mitochondrion membrane 1 CYP27A1
Nucleus 6 CES1, MX2, NR1I2, PGR, RUNX2, TGFB1
cytosol 8 ACP5, CES1, CES2, ELANE, MX2, PGR, PIK3CA, RUNX2
nuclear body 1 NR1I2
phagocytic vesicle 1 ELANE
nucleoplasm 3 NR1I2, PGR, RUNX2
Cell membrane 3 SPP1, TLR4, TNF
lamellipodium 1 PIK3CA
Multi-pass membrane protein 2 HACD1, SPP1
cell surface 5 BMP2, ELANE, TGFB1, TLR4, TNF
Golgi apparatus 1 SPP1
mitochondrial inner membrane 1 CYP27A1
neuronal cell body 2 TGFB1, TNF
Lysosome 1 ACP5
plasma membrane 7 BMP2, PGR, PIK3CA, SPP1, TGFB1, TLR4, TNF
Membrane 4 ACP5, HACD1, MX2, TLR4
axon 1 TGFB1
caveola 1 PTGS2
extracellular exosome 5 AMY2A, BMP3, CES2, ELANE, SPP1
endoplasmic reticulum 4 CES1, CES2, HACD1, PTGS2
extracellular space 7 AMY2A, BMP2, BMP3, ELANE, SPP1, TGFB1, TNF
perinuclear region of cytoplasm 3 PIK3CA, SPP1, TLR4
intercalated disc 1 PIK3CA
mitochondrion 1 CYP27A1
protein-containing complex 1 PTGS2
intracellular membrane-bounded organelle 2 BMP2, CES2
Microsome membrane 1 PTGS2
Single-pass type I membrane protein 1 TLR4
Secreted 4 BMP2, BMP3, SPP1, TGFB1
extracellular region 7 AMY2A, BMP2, BMP3, ELANE, SPP1, TGFB1, TNF
mitochondrial outer membrane 1 PGR
mitochondrial matrix 1 CYP27A1
transcription regulator complex 2 NR1I2, RUNX2
external side of plasma membrane 2 TLR4, TNF
Secreted, extracellular space, extracellular matrix 1 TGFB1
Early endosome 1 TLR4
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Mitochondrion inner membrane 1 CYP27A1
Membrane raft 1 TNF
focal adhesion 1 MAP4K4
microtubule 1 MX2
extracellular matrix 1 TGFB1
collagen-containing extracellular matrix 2 ELANE, TGFB1
secretory granule 2 ELANE, TGFB1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Cell projection, ruffle 1 TLR4
ruffle 1 TLR4
receptor complex 1 TLR4
neuron projection 1 PTGS2
chromatin 3 NR1I2, PGR, RUNX2
cell projection 1 SPP1
phagocytic cup 2 TLR4, TNF
blood microparticle 1 TGFB1
Nucleus, nuclear pore complex 1 MX2
nuclear pore 1 MX2
Lipid droplet 2 CES1, CES2
[Isoform 1]: Endoplasmic reticulum membrane 1 HACD1
intermediate filament cytoskeleton 1 NR1I2
lipopolysaccharide receptor complex 1 TLR4
Golgi lumen 1 TGFB1
endoplasmic reticulum lumen 4 CES1, CES2, PTGS2, SPP1
transcription repressor complex 1 ELANE
platelet alpha granule lumen 1 TGFB1
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
specific granule lumen 1 ELANE
azurophil granule lumen 1 ELANE
Cytoplasmic vesicle, phagosome 1 ELANE
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix 1 TGFB1
[Transforming growth factor beta-1]: Secreted 1 TGFB1
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
[Isoform 4]: Mitochondrion outer membrane 1 PGR
BMP receptor complex 1 BMP2
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Ling Huang, Xunzhi Zhu, Shixing Zhou, Zhenrui Cheng, Kai Shi, Chi Zhang, Hua Shao. Phthalic Acid Esters: Natural Sources and Biological Activities. Toxins. 2021 07; 13(7):. doi: 10.3390/toxins13070495. [PMID: 34357967]
  • Mei-Ling Hou, Li-Wen Chang, Chang-Jung Chiang, Yang-Hwei Tsuang, Chi-Hung Lin, Tung-Hu Tsai. Pharmacokinetics of di-isononyl phthalate in freely moving rats by UPLC-MS/MS. International journal of pharmaceutics. 2013 Jun; 450(1-2):36-43. doi: 10.1016/j.ijpharm.2013.04.033. [PMID: 23618960]
  • Zhi-Yong Guo, Pan-Pan Gai, Jing Duan, Jin-Xia Zhai, Sha-Sha Zhao, Sui Wang, Dan-Yi Wei. Simultaneous determination of phthalates and adipates in human serum using gas chromatography-mass spectrometry with solid-phase extraction. Biomedical chromatography : BMC. 2010 Oct; 24(10):1094-9. doi: 10.1002/bmc.1410. [PMID: 20352652]
  • Xiong-Hao Lin, Yan-Bin Wu, Shan Lin, Jian-Wei Zeng, Pei-Yuan Zeng, Jin-Zhong Wu. Effects of volatile components and ethanolic extract from Eclipta prostrata on proliferation and differentiation of primary osteoblasts. Molecules (Basel, Switzerland). 2010 Jan; 15(1):241-50. doi: 10.3390/molecules15010241. [PMID: 20110887]
  • Shujuan Chen, Jiajia Liu, Hanxiang Gong, Dongliang Yang. [Identification and antibacterial activity of secondary metabolites from Taxus endophytic fungus]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 2009 Mar; 25(3):368-74. doi: . [PMID: 19621576]
  • Fariba Sharififar, Valiolah Mozaffarian, Shirin Moradkhani. Comparison of antioxidant and free radical scavenging activities of the essential oils from flowers and fruits of Otostegia persica Boiss. Pakistan journal of biological sciences : PJBS. 2007 Nov; 10(21):3895-9. doi: 10.3923/pjbs.2007.3895.3899. [PMID: 19090249]
  • Li-Xin Wang, Ling Zhang, Yu-Xia Zhang, Chun-Yan Jin, Chang-Mei Lu, Guo-Rong Wu. [The inhibitory effect of Hydrilla verticillata culture water on Microcystic aeruginosa and its mechanism]. Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology. 2006 Dec; 32(6):672-8. doi: . [PMID: 17167204]
  • You-Xia Wei, Jun-Xian Wang. [Studies on the chemical constituents of hypogeal part from Limonium bicolor]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2006 Nov; 29(11):1182-4. doi: ". [PMID: 17228660]
  • Manori J Silva, Kayoko Kato, Cynthia Wolf, Ella Samandar, Sathya S Silva, Earl L Gray, Larry L Needham, Antonia M Calafat. Urinary biomarkers of di-isononyl phthalate in rats. Toxicology. 2006 Jun; 223(1-2):101-12. doi: 10.1016/j.tox.2006.03.005. [PMID: 16697098]
  • Antonia M Calafat, Manori J Silva, John A Reidy, L Earl Gray, Ella Samandar, James L Preau, Arnetra R Herbert, Larry L Needham. Mono-(3-carboxypropyl) phthalate, a metabolite of di-n-octyl phthalate. Journal of toxicology and environmental health. Part A. 2006 Feb; 69(3-4):215-27. doi: 10.1080/15287390500227381. [PMID: 16263692]