Chlorphenamidine (BioDeep_00001873660)
Main id: BioDeep_00000010127
代谢物信息卡片
N-(4-chloro-2-methylphenyl)-N,N-dimethylformamidine
化学式: C10H13ClN2 (196.0767)
中文名称: 甲醇中杀虫脒溶液
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C=CC(=C1)Cl)N=CN(C)C
InChI: InChI=1S/C10H13ClN2/c1-8-6-9(11)4-5-10(8)12-7-13(2)3/h4-7H,1-3H3
描述信息
D004791 - Enzyme Inhibitors > D008996 - Monoamine Oxidase Inhibitors
D004791 - Enzyme Inhibitors > D014475 - Uncoupling Agents
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals
同义名列表
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:34629
- KEGG: C14746
- PubChem: 22544
- ChEMBL: CHEMBL2288609
- ChEMBL: CHEMBL3186141
- MeSH: Chlorphenamidine
- CAS: 6164-98-3
- PubChem: 17395744
- NIKKAJI: J3.083J
- KNApSAcK: 34629
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yang-Mei-Qing Hu, Hua-Wei Feng, Shuai Liu, Chang Liu, Peng-Yan Zhao, Man Zhang, Li Zhang, Jian Zhao, Jia-Zeng Li, Xiao-Miao Yu, Hong-Sheng Liu, Jun-Feng Zhu. The preparation of polyclonal antibody against chlordimeform and establishment of detection by indirect competitive ELISA.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2022; 57(2):114-124. doi:
10.1080/03601234.2022.2029274. [PMID: 35049417] - Mohamed Ahmed Ibrahim Ahmed, Christoph Franz Adam Vogel. Toxicological Evaluation of Novel Butenolide Pesticide Flupyradifurone Against Culex quinquefasciatus (Diptera: Culicidae) Mosquitoes.
Journal of medical entomology.
2020 11; 57(6):1857-1863. doi:
10.1093/jme/tjaa118. [PMID: 32566941] - Xue Gao, Yongbin Sun, Haidan You, Yannan Dai, Hao Guo, Qingbiao Zhao. Simultaneous determination of amitraz, chlordimeform, formetanate and metabolites in human blood by liquid chromatography tandem mass spectrometry with phospholipid-removal pretreatment.
Biomedical chromatography : BMC.
2019 Apr; 33(4):e4477. doi:
10.1002/bmc.4477. [PMID: 30578570] - Xue Gao, Yanglan Tan, Hao Guo. Simultaneous determination of amitraz, chlordimeform, formetanate and their main metabolites in human urine by high performance liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 May; 1052(?):27-33. doi:
10.1016/j.jchromb.2017.03.004. [PMID: 28346886] - Mohamed Ahmed Ibrahim Ahmed, Christoph Franz Adam Vogel. The role of octopamine receptor agonists in the synergistic toxicity of certain insect growth regulators (IGRs) in controlling Dengue vector Aedes aegypti (Diptera: Culicidae) mosquito.
Acta tropica.
2016 Mar; 155(?):1-5. doi:
10.1016/j.actatropica.2015.11.015. [PMID: 26672383] - Mohamed Ahmed Ibrahim Ahmed, Christoph Franz Adam Vogel. Synergistic action of octopamine receptor agonists on the activity of selected novel insecticides for control of dengue vector Aedes aegypti (Diptera: Culicidae) mosquito.
Pesticide biochemistry and physiology.
2015 May; 120(?):51-6. doi:
10.1016/j.pestbp.2015.01.014. [PMID: 25987220] - Mohamed Ahmed Ibrahim Ahmed, Christoph F A Vogel, Fumio Matsumura. Unique biochemical and molecular biological mechanism of synergistic actions of formamidine compounds on selected pyrethroid and neonicotinoid insecticides on the fourth instar larvae of Aedes aegypti (Diptera: Culicidae).
Pesticide biochemistry and physiology.
2015 May; 120(?):57-63. doi:
10.1016/j.pestbp.2015.01.008. [PMID: 25987221] - Ren-hui He, Yu-peng Bai. [Effect of scopolamine on the acute severe chlorphenamidine poisoning patients].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
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Pest management science.
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Thrombosis and haemostasis.
2002 Jul; 88(1):137-43. doi:
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Toxicology and applied pharmacology.
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Deutsche medizinische Wochenschrift (1946).
1991 May; 116(21):816-8. doi:
10.1055/s-2008-1063684. [PMID: 2032533] - J M Goldman, R L Cooper, T L Edwards, G L Rehnberg, W K McElroy, J F Hein. Suppression of the luteinizing hormone surge by chlordimeform in ovariectomized, steroid-primed female rats.
Pharmacology & toxicology.
1991 Feb; 68(2):131-6. doi:
10.1111/j.1600-0773.1991.tb02050.x. [PMID: 1852718] - T E Stoker, J M Goldman, R L Cooper, W K McElroy. Influence of chlordimeform on alpha-adrenergic receptor-associated mechanisms of hormonal regulation in the rat: pituitary and adrenocortical secretion.
Toxicology.
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10.1016/0300-483x(91)90185-4. [PMID: 1658985] - J M Goldman, R L Cooper, S C Laws, G L Rehnberg, T L Edwards, W K McElroy, J F Hein. Chlordimeform-induced alterations in endocrine regulation within the male rat reproductive system.
Toxicology and applied pharmacology.
1990 Jun; 104(1):25-35. doi:
10.1016/0041-008x(90)90279-4. [PMID: 2113720] - D Wu, L G Costa, S D Murphy. [The effect of pesticides-CDM and AMZ on inhibition of the binding of 3H-clonidine to alpha 2-adrenoreceptor in rat forebrain tissue].
Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao.
1990 Mar; 21(1):17-21. doi:
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Neurotoxicology and teratology.
1989 Jul; 11(4):405-11. doi:
10.1016/0892-0362(89)90014-7. [PMID: 2552275] - C Lemesch, Y Wolf, E Gabai. Occupational exposure to chlordimeform in Israel.
Israel journal of medical sciences.
1987 Dec; 23(12):1261-2. doi:
NULL. [PMID: 3440752] - P H Kurtz, G Shaw, A Kelter, R J Jackson. Assessment of potential acute health effects in agricultural workers exposed during the application of chlordimeform.
Journal of occupational medicine. : official publication of the Industrial Medical Association.
1987 Jul; 29(7):592-5. doi:
NULL. [PMID: 3612336] - R Geyer, F Fattal. HPLC determination of the metabolite 4-chloro-o-toluidine in the urine of workers occupationally exposed to chlordimeform.
Journal of analytical toxicology.
1987 Jan; 11(1):24-6. doi:
10.1093/jat/11.1.24. [PMID: 3821074] - K T Maddy, J B Knaak, D B Gibbons. Monitoring the urine of pesticide applicators in California for residues of chlordimeform and its metabolites 1982-1985.
Toxicology letters.
1986 Oct; 33(1-3):37-44. doi:
10.1016/0378-4274(86)90069-x. [PMID: 3775820] - T L Johnson, C O Knowles. Formamidine-mediated inhibition of rat platelet aggregation.
General pharmacology.
1985; 16(4):321-5. doi:
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Toxicology.
1984 May; 31(2):91-8. doi:
10.1016/0300-483x(84)90001-5. [PMID: 6740694] - P J Morgan, W Mordue. 5-Hydroxytryptamine stimulates fluid secretion in locust malpighian tubules independently of cAMP.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.
1984; 79(2):305-10. doi:
10.1016/0742-8413(84)90205-6. [PMID: 6151458] - J K Pollak, W Harsas. Effects of organochlorine compounds on lipid catabolism of foetal rat liver mitochondria and microsomes.
Bulletin of environmental contamination and toxicology.
1982 Mar; 28(3):313-8. doi:
10.1007/bf01608513. [PMID: 7082871] - F Kaloyanova, A Bainova, Z Zaprianov. Inhibition of monoamine oxidase activity after combined action of chlordimeform with the antidepressant nialamide.
Archives of environmental contamination and toxicology.
1981; 10(1):1-8. doi:
10.1007/bf01057570. [PMID: 7235738] - H Iizuka, T Masuda. Residual fate of chlorphenamidine in rice plant and paddy soil.
Bulletin of environmental contamination and toxicology.
1979 Aug; 22(6):745-9. doi:
10.1007/bf02027018. [PMID: 486779] - J T Pento, C P Robinson, J A Rieger, F A Horton. The influence of chlordimeform on calcium and glucose homeostasis.
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1979 Apr; 24(1):127-42. doi:
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10.1007/978-1-4684-3593-1_47. [PMID: 121203] - D S Folland, R D Kimbrough, R E Cline, R C Swiggart, W Schaffner. Acute hemorrhagic cystitis. Industrial exposure to the pesticide chlordimeform.
JAMA.
1978 Mar; 239(11):1052-5. doi:
10.1001/jama.239.11.1052. [PMID: 628051] - C O Knowles, H J Benezet. Mammalian metabolism of chlordimeform. Formation of metabolites containing the urea moiety.
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1977 Sep; 25(5):1022-6. doi:
10.1021/jf60213a058. [PMID: 893824] - T Arima, H Morooka, T Tanigawa, M Imai, T Tsunashima, S Kita. Methemoglobinemia induced by chlorphenamidine.
Acta medica Okayama.
1976 Feb; 30(1):57-60. doi:
. [PMID: 135479] - H J Benezet, C O Knowles. N'-(4-Chloro-o-tolyl)-N-methylformamidine (demethylchlordimeform) metabolism in the rat.
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