DL-ETHIONINE (BioDeep_00001871974)
代谢物信息卡片
DL-ETHIONINE
化学式: C6H13NO2S (163.0667)
中文名称: DL-乙硫氨酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCSCCC(C(=O)O)N
InChI: InChI=1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Erik Alm, Tove Slagbrand, K Magnus Aberg, Erik Wahlström, Ingela Gustafsson, Johan Lindberg. Automated annotation and quantification of metabolites in 1H NMR data of biological origin.
Analytical and bioanalytical chemistry.
2012 Apr; 403(2):443-55. doi:
10.1007/s00216-012-5789-x. [PMID: 22362275] - Jessie Fernandez, Janet D Wright, David Hartline, Cristian F Quispe, Nandakumar Madayiputhiya, Richard A Wilson. Principles of carbon catabolite repression in the rice blast fungus: Tps1, Nmr1-3, and a MATE-family pump regulate glucose metabolism during infection.
PLoS genetics.
2012; 8(5):e1002673. doi:
10.1371/journal.pgen.1002673. [PMID: 22570632] - Soo-Jung Lee, Myung-Hee Kang, Hyesun Min. Folic acid supplementation reduces oxidative stress and hepatic toxicity in rats treated chronically with ethanol.
Nutrition research and practice.
2011 Dec; 5(6):520-6. doi:
10.4162/nrp.2011.5.6.520. [PMID: 22259676] - Suzanne Geenen, Cristina Guallar-Hoyas, Filippos Michopoulos, J Gerry Kenna, Kyle L Kolaja, Hans V Westerhoff, Paul Thomas, Ian D Wilson. HPLC-MS/MS methods for the quantitative analysis of 5-oxoproline (pyroglutamate) in rat plasma and hepatic cell line culture medium.
Journal of pharmaceutical and biomedical analysis.
2011 Nov; 56(3):655-63. doi:
10.1016/j.jpba.2011.06.001. [PMID: 21752568] - Agnès Fourcot, Dominique Couchie, Marie-Noele Chobert, Elie-Serge Zafrani, Philippe Mavier, Yannick Laperche, Arthur Brouillet. Gas6 deficiency prevents liver inflammation, steatohepatitis, and fibrosis in mice.
American journal of physiology. Gastrointestinal and liver physiology.
2011 Jun; 300(6):G1043-53. doi:
10.1152/ajpgi.00311.2010. [PMID: 21350191] - Mahmoud Rushdi Abd Ellah. The role of liver biopsy in detection of hepatic oxidative stress.
Veterinary medicine international.
2011 Feb; 2011(?):613602. doi:
10.4061/2011/613602. [PMID: 21403828] - Abbass Ghanbari-Niaki, Rahelah Soltani, Afsaneh Shemshaki, Robert R Kraemer. Effects of acute ethionine injection on plasma ghrelin and obestatin levels in trained male rats.
Metabolism: clinical and experimental.
2010 Jul; 59(7):982-7. doi:
10.1016/j.metabol.2009.10.020. [PMID: 20045146] - Schonna R Manning, John W La Claire. Prymnesins: toxic metabolites of the golden alga, Prymnesium parvum Carter (Haptophyta).
Marine drugs.
2010 Mar; 8(3):678-704. doi:
10.3390/md8030678. [PMID: 20411121] - Erik Alm, Ralf J O Torgrip, K Magnus Aberg, Ina Schuppe-Koistinen, Johan Lindberg. Time-resolved biomarker discovery in 1H-NMR data using generalized fuzzy Hough transform alignment and parallel factor analysis.
Analytical and bioanalytical chemistry.
2010 Mar; 396(5):1681-9. doi:
10.1007/s00216-009-3421-5. [PMID: 20087727] - Tuncay Baubec, Huy Q Dinh, Ales Pecinka, Branislava Rakic, Wilfried Rozhon, Bonnie Wohlrab, Arndt von Haeseler, Ortrun Mittelsten Scheid. Cooperation of multiple chromatin modifications can generate unanticipated stability of epigenetic States in Arabidopsis.
The Plant cell.
2010 Jan; 22(1):34-47. doi:
10.1105/tpc.109.072819. [PMID: 20097869] - Mahmoud R Abd Ellah, Keiji Okada, Masanobu Goryo, Akihiro Oishi, Jun Yasuda. Superoxide dismutase activity as a measure of hepatic oxidative stress in cattle following ethionine administration.
Veterinary journal (London, England : 1997).
2009 Nov; 182(2):336-41. doi:
10.1016/j.tvjl.2008.05.013. [PMID: 18585936] - Takanari Nakano, Ikuo Inoue, Shigehiro Katayama, Makoto Seo, Seiichiro Takahashi, Shigeru Hokari, Rina Shinozaki, Kazuhisa Hatayama, Tsugikazu Komoda. Lysophosphatidylcholine for efficient intestinal lipid absorption and lipoprotein secretion in caco-2 cells.
Journal of clinical biochemistry and nutrition.
2009 Sep; 45(2):227-34. doi:
10.3164/jcbn.09-25. [PMID: 19794933] - Mitsuhiro Hirode, Ko Omura, Naoki Kiyosawa, Takeki Uehara, Toshinobu Shimuzu, Atsushi Ono, Toshikazu Miyagishima, Taku Nagao, Yasuo Ohno, Tetsuro Urushidani. Gene expression profiling in rat liver treated with various hepatotoxic-compounds inducing coagulopathy.
The Journal of toxicological sciences.
2009 Jun; 34(3):281-93. doi:
10.2131/jts.34.281. [PMID: 19483382] - Runkuan Yang, Angel L Shaufl, Meaghan E Killeen, Mitchell P Fink. Ethyl pyruvate ameliorates liver injury secondary to severe acute pancreatitis.
The Journal of surgical research.
2009 May; 153(2):302-9. doi:
10.1016/j.jss.2008.04.004. [PMID: 19027919] - Jiankun Duan, Bin Hu. Separation and determination of seleno amino acids using gas chromatography hyphenated with inductively coupled plasma mass spectrometry after hollow fiber liquid phase microextraction.
Journal of mass spectrometry : JMS.
2009 May; 44(5):605-12. doi:
10.1002/jms.1533. [PMID: 19053158] - Emey Suhana Mohd Azamai, Suhaniza Sulaiman, Shafina Hanim Mohd Habib, Mee Lee Looi, Srijit Das, Nor Aini Abdul Hamid, Wan Zurinah Wan Ngah, Yasmin Anum Mohd Yusof. Chlorella vulgaris triggers apoptosis in hepatocarcinogenesis-induced rats.
Journal of Zhejiang University. Science. B.
2009 Jan; 10(1):14-21. doi:
10.1631/jzus.b0820168. [PMID: 19198018] - Isamu Yamaguchi, Kentaro Hamada, Masanori Yoshida, Hiroyuki Isayama, Shuichi Kanazashi, Koji Takeuchi. Risperidone attenuates local and systemic inflammatory responses to ameliorate diet-induced severe necrotic pancreatitis in mice: it may provide a new therapy for acute pancreatitis.
The Journal of pharmacology and experimental therapeutics.
2009 Jan; 328(1):256-62. doi:
10.1124/jpet.108.141895. [PMID: 18832108] - Hyesun Min. Effects of dietary supplementation of high-dose folic acid on biomarkers of methylating reaction in vitamin B(12)-deficient rats.
Nutrition research and practice.
2009; 3(2):122-7. doi:
10.4162/nrp.2009.3.2.122. [PMID: 20016712] - Shafina Hanim Mohd Habib, Suzana Makpol, Noor Aini Abdul Hamid, Srijit Das, Wan Zurinah Wan Ngah, Yasmin Anum Mohd Yusof. Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats.
Clinics (Sao Paulo, Brazil).
2008 Dec; 63(6):807-13. doi:
10.1590/s1807-59322008000600017. [PMID: 19061005] - Yasmin Anum Mohd Yusof, Norliza Ahmad, Srijit Das, Suhaniza Sulaiman, Nor Azian Murad. Chemopreventive efficacy of ginger (Zingiber officinale) in ethionine induced rat hepatocarcinogenesis.
African journal of traditional, complementary, and alternative medicines : AJTCAM.
2008 Oct; 6(1):87-93. doi:
10.4314/ajtcam.v6i1.57078. [PMID: 20162046] - Muhammad K Saeed, Yulin Deng, Rongji Dai. Attenuation of Biochemical Parameters in Streptozotocin-induced Diabetic Rats by Oral Administration of Extracts and Fractions of Cephalotaxus sinensis.
Journal of clinical biochemistry and nutrition.
2008 Jan; 42(?):21-8. doi:
10.3164/jcbn2008004. [PMID: 18231626] - Eleni Skordi, Ivan K S Yap, Sandrine P Claus, François-Pierre J Martin, Olivier Cloarec, Johan Lindberg, Ina Schuppe-Koistinen, Elaine Holmes, Jeremy K Nicholson. Analysis of time-related metabolic fluctuations induced by ethionine in the rat.
Journal of proteome research.
2007 Dec; 6(12):4572-81. doi:
10.1021/pr070268q. [PMID: 17966971] - Percy Ho, K F Kong, Y H Chan, Jimmy S H Tsang, Joseph T Y Wong. An unusual S-adenosylmethionine synthetase gene from dinoflagellate is methylated.
BMC molecular biology.
2007 Oct; 8(?):87. doi:
10.1186/1471-2199-8-87. [PMID: 17915037] - R Mota, F Sánchez-Bueno, J J Berenguer-Pina, D Hernández-Espinosa, P Parrilla, J Yélamos. Therapeutic treatment with poly(ADP-ribose) polymerase inhibitors attenuates the severity of acute pancreatitis and associated liver and lung injury.
British journal of pharmacology.
2007 Aug; 151(7):998-1005. doi:
10.1038/sj.bjp.0707310. [PMID: 17533414] - Keith D Gray, Misho O Simovic, Timothy S Blackwell, John W Christman, Addison K May, Kelly S Parman, William C Chapman, Steven C Stain. Activation of nuclear factor kappa B and severe hepatic necrosis may mediate systemic inflammation in choline-deficient/ethionine-supplemented diet-induced pancreatitis.
Pancreas.
2006 Oct; 33(3):260-7. doi:
10.1097/01.mpa.0000240599.95817.34. [PMID: 17003648] - Taketoshi Ogawa, Atsuhiro Sugidachi, Naoki Tanaka, Koichi Fujimoto, Jun-ichiro Fukushige, Yoshiro Tani, Fumitoshi Asai. Effects of R-102444 and its active metabolite R-96544, selective 5-HT2A receptor antagonists, on experimental acute and chronic pancreatitis: Additional evidence for possible involvement of 5-HT2A receptors in the development of experimental pancreatitis.
European journal of pharmacology.
2005 Oct; 521(1-3):156-63. doi:
10.1016/j.ejphar.2005.08.033. [PMID: 16183055] - Yasuyuki Kihara, Hiroyuki Yoshikawa, Hidekazu Honda, Ken-ichirou Fukumitsu, Taizou Yamaguchi, Makoto Otsuki. Natural disruption of group 2 phospholipase A2 gene protects against choline-deficient ethionine-supplemented diet-induced acute pancreatitis and lung injury.
Pancreas.
2005 Jul; 31(1):48-53. doi:
10.1097/01.mpa.0000168223.43709.28. [PMID: 15968247] - Jongwon Choi, Jung-Kwan Park, Kyung-Tae Lee, Kwang-Kyun Park, Won-Bae Kim, Jin-Ha Lee, Hyun-Ju Jung, Hee-Juhn Park. In vivo antihepatotoxic effects of Ligularia fischeri var. spiciformis and the identification of the active component, 3,4-dicaffeoylquinic acid.
Journal of medicinal food.
2005; 8(3):348-52. doi:
10.1089/jmf.2005.8.348. [PMID: 16176146] - Vance B Matthews, Elizabeth Klinken, George C T Yeoh. Direct effects of interleukin-6 on liver progenitor oval cells in culture.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
2004 Nov; 12(6):650-6. doi:
10.1111/j.1067-1927.2004.12605.x. [PMID: 15555057] - Lena Trulsson, Per Sandström, Tommy Sundqvist, Staffan Smeds, Thomas Gasslander, Joar Svanvik. The Influence of a load of L-arginine on serum amino acids and pancreatic apoptosis/proliferation and ATP levels in the rat.
Pancreas.
2004 Nov; 29(4):e113-20. doi:
10.1097/00006676-200411000-00165. [PMID: 15502637] - Atsushi Nitanai, Norio Katoh, Shin Oikawa, Masakazu Saitoh, Masaomi Hamada, Akihito Kutsuzawa, Tharwat Mohamed, Eiji Uchida, Daiji Endoh, Takashi Kurosawa, Hiroshi Sato. Decreases in serum apolipoprotein C-III concentration in cows with ethionine-induced fatty liver.
The Journal of veterinary medical science.
2004 Sep; 66(9):1113-8. doi:
10.1292/jvms.66.1113. [PMID: 15472476] - Runkuan Yang, Takashi Uchiyama, Sean M Alber, Xiaonan Han, Simon K Watkins, Russell L Delude, Mitchell P Fink. Ethyl pyruvate ameliorates distant organ injury in a murine model of acute necrotizing pancreatitis.
Critical care medicine.
2004 Jul; 32(7):1453-9. doi:
10.1097/01.ccm.0000130835.65462.06. [PMID: 15241088] - Fatma Aiad, Basiouny El-Gamal, Jehan Al-Meer, Zinab El-Kerdasy, Nadia Zakhary, Abdelbaset El-Aaser. Protective effect of soybean against hepatocarcinogenesis induced by DL-ethionine.
Journal of biochemistry and molecular biology.
2004 May; 37(3):370-5. doi:
10.5483/bmbrep.2004.37.3.370. [PMID: 15469721] - T Andrew Clayton, John C Lindon, Jeremy R Everett, Claude Charuel, Gilles Hanton, Jean-Loic Le Net, Jean-Pierre Provost, Jeremy K Nicholson. Hepatotoxin-induced hypercreatinaemia and hypercreatinuria: their relationship to one another, to liver damage and to weakened nutritional status.
Archives of toxicology.
2004 Feb; 78(2):86-96. doi:
10.1007/s00204-003-0515-2. [PMID: 14520508] - P Chowdhury. An exploratory study on the development of an animal model of acute pancreatitis following nicotine exposure.
Tobacco induced diseases.
2003 Sep; 1(3):213-7. doi:
10.1186/1617-9625-1-3-213. [PMID: 19570262] - Rong Di, Jungsup Kim, Melinda N Martin, Tom Leustek, Jinwoo Jhoo, Chi-Tang Ho, Nilgun E Tumer. Enhancement of the primary flavor compound methional in potato by increasing the level of soluble methionine.
Journal of agricultural and food chemistry.
2003 Sep; 51(19):5695-702. doi:
10.1021/jf030148c. [PMID: 12952421] - T Andrew Clayton, John C Lindon, Jeremy R Everett, Claude Charuel, Gilles Hanton, Jean-Loic Le Net, Jean-Pierre Provost, Jeremy K Nicholson. An hypothesis for a mechanism underlying hepatotoxin-induced hypercreatinuria.
Archives of toxicology.
2003 Apr; 77(4):208-17. doi:
10.1007/s00204-002-0431-x. [PMID: 12698236] - Yoshitaka Sakai, Atsushi Masamune, Akihiko Satoh, Jun Nishihira, Tetsuya Yamagiwa, Tooru Shimosegawa. Macrophage migration inhibitory factor is a critical mediator of severe acute pancreatitis.
Gastroenterology.
2003 Mar; 124(3):725-36. doi:
10.1053/gast.2003.50099. [PMID: 12612911] - D Papagoras, E J Giamarellos-Bourboulis, M Kanara, G Douridas, I Paraskevopoulos, G Antzaklis, P Karayannacos, H Giamarellou. Pancreatic concentrations of cefepime in experimental necrotizing pancreatitis.
Journal of chemotherapy (Florence, Italy).
2003 Feb; 15(1):43-6. doi:
10.1179/joc.2003.15.1.43. [PMID: 12678413] - Takaya Sato, Junichi Niikawa, Ichiro Usui, Tsunao Imamura, Hitoshi Yoshida, Shigeki Tanaka, Keiji Mitamura. Pancreatic regeneration after ethionine-induced acute pancreatitis in rats lacking pancreatic CCK-A receptor gene expression.
Journal of gastroenterology.
2003; 38(7):672-80. doi:
10.1007/s00535-003-1120-0. [PMID: 12898360] - Tsunao Imamura, Junichi Niikawa, Katsuya Kitamura, Akira Takahashi, Akitoshi Ikegami, Hitoshi Yoshida, Shigeki Tanaka, Keiji Mitamura. Effect of IS-741 on ethionine-induced acute pancreatitis in rats: relation to pancreatic acinar cell regeneration.
Journal of gastroenterology.
2003; 38(3):260-7. doi:
10.1007/s005350300045. [PMID: 12673449] - Kimihiro Ominato, Hiroshi Akita, Akinori Suzuki, Fumiko Kijima, Takashi Yoshino, Michiko Yoshino, Yukako Chiba, Hitoshi Onouchi, Satoshi Naito. Identification of a short highly conserved amino acid sequence as the functional region required for posttranscriptional autoregulation of the cystathionine gamma-synthase gene in Arabidopsis.
The Journal of biological chemistry.
2002 Sep; 277(39):36380-6. doi:
10.1074/jbc.m204645200. [PMID: 12121993] - Martina Wein, Noa Lavid, Stefan Lunkenbein, Efraim Lewinsohn, Wilfried Schwab, Ralf Kaldenhoff. Isolation, cloning and expression of a multifunctional O-methyltransferase capable of forming 2,5-dimethyl-4-methoxy-3(2H)-furanone, one of the key aroma compounds in strawberry fruits.
The Plant journal : for cell and molecular biology.
2002 Sep; 31(6):755-65. doi:
10.1046/j.1365-313x.2002.01396.x. [PMID: 12220266] - Derek B Goto, Makoto Ogi, Fumiko Kijima, Tomoko Kumagai, Folkert van Werven, Hitoshi Onouchi, Satoshi Naito. A single-nucleotide mutation in a gene encoding S-adenosylmethionine synthetase is associated with methionine over-accumulation phenotype in Arabidopsis thaliana.
Genes & genetic systems.
2002 Apr; 77(2):89-95. doi:
10.1266/ggs.77.89. [PMID: 12087191] - Bo Shen, Changjiang Li, Mitchell C Tarczynski. High free-methionine and decreased lignin content result from a mutation in the Arabidopsis S-adenosyl-L-methionine synthetase 3 gene.
The Plant journal : for cell and molecular biology.
2002 Feb; 29(3):371-80. doi:
10.1046/j.1365-313x.2002.01221.x. [PMID: 11844113] - M Govendir, P J Canfield, D R Emslie, A D J Watson, D B Church. Evaluation of d,l-ethionine as a mechanism for pancreatic islet regeneration in dogs.
Australian veterinary journal.
2002 Jan; 80(1-2):75-82; discussion 82. doi:
. [PMID: 12180885] - M K McMillian, E R Grant, Z Zhong, J B Parker, L Li, R A Zivin, M E Burczynski, M D Johnson. Nile Red binding to HepG2 cells: an improved assay for in vitro studies of hepatosteatosis.
In vitro & molecular toxicology.
2001; 14(3):177-90. doi:
10.1089/109793301753407948. [PMID: 11846991] - W W Barrow, E L Wright, K S Goh, N Rastogi. Activities of fluoroquinolone, macrolide, and aminoglycoside drugs combined with inhibitors of glycosylation and fatty acid and peptide biosynthesis against Mycobacterium avium.
Antimicrobial agents and chemotherapy.
1993 Apr; 37(4):652-61. doi:
10.1128/aac.37.4.652. [PMID: 8494359] - H Isaacs, J J Heffron, M Badenhorst. 'Picture frame' fibres in a carrier of the trait for malignant hyperpyrexia.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
1975 Nov; 49(46):1923-6. doi:
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