2,4-Quinolinediol (BioDeep_00001871896)

Main id: BioDeep_00000001215

 


代谢物信息卡片


4-Hydroxyquinolin-2(1H)-one

化学式: C9H7NO2 (161.0477)
中文名称: 2,4-二羟基喹啉, 2,4-喹啉二醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=CC(=O)N2)O
InChI: InChI=1S/C9H7NO2/c11-8-5-9(12)10-7-4-2-1-3-6(7)8/h1-5H,(H2,10,11,12)



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 CDK5, CEL, CNR1, CNR2, PLA2G12A, TNK1
Peripheral membrane protein 1 TNK1
Endoplasmic reticulum membrane 1 CD4
Nucleus 1 CDK5
cytosol 2 CDK5, DCTN5
dendrite 2 CDK5, CNR2
centrosome 1 DCTN5
nucleoplasm 2 CDK5, DCTN5
Cell membrane 3 CD4, CDK5, CNR1
lamellipodium 1 CDK5
Cell projection, axon 1 CNR1
Cell projection, growth cone 1 CDK5
Multi-pass membrane protein 1 CNR1
Synapse 1 CDK5
cell junction 1 CDK5
glutamatergic synapse 1 CNR1
growth cone 2 CDK5, CNR1
neuromuscular junction 1 CDK5
neuronal cell body 1 CDK5
presynaptic membrane 1 CNR1
Presynapse 2 CDK5, CNR1
plasma membrane 6 CD4, CDK5, CNR1, CNR2, IGHE, TNK1
Membrane 2 CDK5, TNK1
axon 2 CDK5, CNR1
extracellular exosome 1 CEL
endoplasmic reticulum 1 CNR2
extracellular space 2 CEL, IGHE
filopodium 1 CDK5
postsynaptic density 1 CDK5
protein kinase 5 complex 1 CDK5
Single-pass type I membrane protein 2 CD4, IGHE
Secreted 2 CEL, PLA2G12A
extracellular region 3 CEL, IGHE, PLA2G12A
Mitochondrion outer membrane 1 CNR1
mitochondrial outer membrane 1 CNR1
nuclear membrane 1 DCTN5
external side of plasma membrane 1 CD4
actin cytoskeleton 1 CNR1
perikaryon 2 CDK5, CNR2
Early endosome 1 CD4
postsynaptic membrane 1 CNR2
Cell projection, lamellipodium 1 CDK5
Membrane raft 2 CD4, CNR1
Cytoplasm, cytoskeleton 1 DCTN5
GABA-ergic synapse 1 CNR1
neuron projection 1 CDK5
IgE immunoglobulin complex 1 IGHE
[Isoform 2]: Cell membrane 1 IGHE
Chromosome, centromere, kinetochore 1 DCTN5
Cell projection, dendrite 1 CNR2
[Isoform 1]: Cytoplasm 1 CDK5
endoplasmic reticulum lumen 1 CD4
dynactin complex 1 DCTN5
kinetochore 1 DCTN5
clathrin-coated endocytic vesicle membrane 1 CD4
extrinsic component of cytoplasmic side of plasma membrane 1 CNR2
[Isoform 3]: Cell membrane 1 IGHE
cyclin-dependent protein kinase holoenzyme complex 1 CDK5
T cell receptor complex 1 CD4
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE


文献列表

  • Giordano Rampioni, Christian Pustelny, Matthew P Fletcher, Victoria J Wright, Mary Bruce, Kendra P Rumbaugh, Stephan Heeb, Miguel Cámara, Paul Williams. Transcriptomic analysis reveals a global alkyl-quinolone-independent regulatory role for PqsE in facilitating the environmental adaptation of Pseudomonas aeruginosa to plant and animal hosts. Environmental microbiology. 2010 Jun; 12(6):1659-73. doi: 10.1111/j.1462-2920.2010.02214.x. [PMID: 20406282]
  • Takeshi Fuchigami, Terushi Haradahira, Noriko Fujimoto, Yumiko Nojiri, Takahiro Mukai, Fumihiko Yamamoto, Takashi Okauchi, Jun Maeda, Kazutoshi Suzuki, Tetsuya Suhara, Hiroshi Yamaguchi, Mikako Ogawa, Yasuhiro Magata, Minoru Maeda. Development of N-[11C]methylamino 4-hydroxy-2(1H)-quinolone derivatives as PET radioligands for the glycine-binding site of NMDA receptors. Bioorganic & medicinal chemistry. 2009 Aug; 17(15):5665-75. doi: 10.1016/j.bmc.2009.06.014. [PMID: 19586774]
  • Anthony Fardet, Rafael Llorach, Jean-François Martin, Catherine Besson, Bernard Lyan, Estelle Pujos-Guillot, Augustin Scalbert. A liquid chromatography-quadrupole time-of-flight (LC-QTOF)-based metabolomic approach reveals new metabolic effects of catechin in rats fed high-fat diets. Journal of proteome research. 2008 Jun; 7(6):2388-98. doi: 10.1021/pr800034h. [PMID: 18484765]
  • Amal M El-Shennawy, Amira H Mohamed, Mohamed Abass. Studies on parasitologic and haematologic activities of an enaminone derivative of 4-hydroxyquinolin-2(1H)-one against murine schistosomiasis mansoni. MedGenMed : Medscape general medicine. 2007 Jan; 9(1):15. doi: . [PMID: 17435624]