5-Hydroxyindole-3-acetaldehyde (BioDeep_00001869030)

Main id: BioDeep_00000005888

 


代谢物信息卡片


5-Hydroxyindole-3-acetaldehyde

化学式: C10H9NO2 (175.0633)
中文名称: 5-羟基吲哚-3-乙醛
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC2=C(C=C1O)C(=CN2)CC=O
InChI: InChI=1S/C10H9NO2/c12-4-3-7-6-11-10-2-1-8(13)5-9(7)10/h1-2,4-6,11,13H,3H2

描述信息

D006133 - Growth Substances > D010937 - Plant Growth Regulators > D007210 - Indoleacetic Acids
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

2 个代谢物同义名

5-Hydroxyindole-3-acetaldehyde; 5-Hydroxyindole-3-acetaldehyde



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(10)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 CASP3, PFDN5, PIK3CA, SNCA
Peripheral membrane protein 1 CYP1B1
Endoplasmic reticulum membrane 3 CYP1A2, CYP1B1, HMOX1
Mitochondrion membrane 1 MAOA
Nucleus 5 CASP3, EMX2, HMOX1, PFDN5, SNCA
cytosol 8 AKR1A1, CASP3, HMOX1, KMO, MAOA, PFDN5, PIK3CA, SNCA
nucleoplasm 2 CASP3, HMOX1
Cytoplasmic side 2 HMOX1, MAOA
lamellipodium 1 PIK3CA
Cell projection, axon 2 EMX2, SNCA
Multi-pass membrane protein 1 KMO
Synapse 2 AKR1A1, SNCA
cell cortex 1 SNCA
glutamatergic synapse 1 CASP3
growth cone 1 SNCA
neuronal cell body 2 CASP3, SNCA
postsynapse 1 SNCA
Cytoplasm, cytosol 1 AKR1A1
Lysosome 1 SNCA
plasma membrane 2 PIK3CA, SNCA
synaptic vesicle membrane 1 SNCA
Membrane 5 CYP1B1, HMOX1, KMO, MAOA, SNCA
apical plasma membrane 1 AKR1A1
axon 2 EMX2, SNCA
extracellular exosome 1 AKR1A1
endoplasmic reticulum 1 HMOX1
extracellular space 5 AKR1A1, HMOX1, IL2, KMO, SNCA
perinuclear region of cytoplasm 3 HMOX1, PIK3CA, SNCA
intercalated disc 1 PIK3CA
mitochondrion 5 ABAT, CYP1B1, KMO, MAOA, SNCA
protein-containing complex 1 SNCA
intracellular membrane-bounded organelle 2 CYP1A2, CYP1B1
Microsome membrane 2 CYP1A2, CYP1B1
postsynaptic density 1 CASP3
Secreted 2 IL2, SNCA
extracellular region 2 IL2, SNCA
Mitochondrion outer membrane 2 KMO, MAOA
Single-pass membrane protein 1 MAOA
mitochondrial outer membrane 3 HMOX1, KMO, MAOA
mitochondrial matrix 1 ABAT
actin cytoskeleton 1 SNCA
Apical cell membrane 1 AKR1A1
chromatin 1 EMX2
supramolecular fiber 1 SNCA
intermediate filament cytoskeleton 1 PFDN5
axon terminus 1 SNCA
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
Single-pass type IV membrane protein 2 HMOX1, MAOA
prefoldin complex 1 PFDN5
death-inducing signaling complex 1 CASP3
inclusion body 1 SNCA
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
4-aminobutyrate transaminase complex 1 ABAT


文献列表

  • Saki Yoshino, Aya Hara, Hiroyuki Sakakibara, Kyuichi Kawabata, Akira Tokumura, Akari Ishisaka, Yoshichika Kawai, Junji Terao. Effect of quercetin and glucuronide metabolites on the monoamine oxidase-A reaction in mouse brain mitochondria. Nutrition (Burbank, Los Angeles County, Calif.). 2011 Jul; 27(7-8):847-52. doi: 10.1016/j.nut.2010.09.002. [PMID: 21371861]
  • Xiaochao Ma, Chi Chen, Kristopher W Krausz, Jeffrey R Idle, Frank J Gonzalez. A metabolomic perspective of melatonin metabolism in the mouse. Endocrinology. 2008 Apr; 149(4):1869-79. doi: 10.1210/en.2007-1412. [PMID: 18187545]
  • A Yazar, K Büyükafpar, G Polat, C Pata, A Kanýk, E N Tiftik, O Bağdatoğlu. The urinary 5-hydroxyindole acetic acid and plasma nitric oxide levels in irritable bowel syndrome: a preliminary study. Scottish medical journal. 2005 Feb; 50(1):27-9. doi: 10.1177/003693300505000111. [PMID: 15792386]
  • M Some, S Svensson, J O Höög, A Helander. Studies on the interaction between ethanol and serotonin metabolism in rat, using deuterated ethanol and 4-methylpyrazole. Biochemical pharmacology. 2000 Feb; 59(4):385-91. doi: 10.1016/s0006-2952(99)00336-6. [PMID: 10644046]
  • A Helander, O Tottmar. Metabolism of biogenic aldehydes in isolated human blood cells, platelets and in plasma. Biochemical pharmacology. 1987 Apr; 36(7):1077-82. doi: 10.1016/0006-2952(87)90417-5. [PMID: 2436624]
  • A Helander, O Tottmar. Metabolism of biogenic aldehydes in human blood: effects of ethanol, acetaldehyde and disulfiram. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. 1987; 1(?):193-7. doi: . [PMID: 2447900]