Para-Cresidine (BioDeep_00001868220)

Main id: BioDeep_00000002224

 


代谢物信息卡片


2-Methoxy-5-methylaniline

化学式: C8H11NO (137.0841)
中文名称: 3-氨基对甲苯甲醚, 2-甲氧基-5-甲基苯胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CC(=C(C=C1)OC)N
InChI: InChI=1S/C8H11NO/c1-6-3-4-8(10-2)7(9)5-6/h3-5H,9H2,1-2H3

描述信息

同义名列表

4 个代谢物同义名

2-Methoxy-5-methylaniline; Para-Cresidine; para-Cresidine; 2-Methoxy-5-methylaniline



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 BTG2, CCNF, CCNG1, CDKN1A, GDF15, HMGB2, KRT5, MYC, PHLDA3, PLK2, RPL22, TUBB4B
Peripheral membrane protein 1 PHLDA3
Nucleus 16 AEN, BTG2, CCNF, CCNG1, CDKN1A, GDF15, HMGB2, KRT5, LRP1, MBD1, MKI67, MYC, PLK2, RPL22, TUBB4B, XPA
cytosol 8 BTG2, CCNF, CDKN1A, CLC, KRT5, PLK2, RPL22, TUBB4B
dendrite 2 CCNG1, PLK2
nuclear body 2 CDKN1A, MKI67
centrosome 2 CCNF, PLK2
nucleoplasm 8 AEN, CCNG1, CDKN1A, HMGB2, MBD1, MKI67, MYC, XPA
Cytoplasmic granule 1 CLC
cell junction 1 CCNF
glutamatergic synapse 1 RPL22
Golgi apparatus 2 GDF15, LRP1
lysosomal membrane 1 LRP1
neuronal cell body 1 CCNG1
Cytoplasm, cytosol 1 CLC
Presynapse 1 RPL22
plasma membrane 2 LRP1, PHLDA3
Membrane 5 KRT5, LRP1, MKI67, MYC, PHLDA3
basolateral plasma membrane 1 LRP1
extracellular exosome 5 BTG2, GDF15, KRT5, RPL22, TUBB4B
extracellular space 4 CLC, GDF15, HMGB2, IGF1
perinuclear region of cytoplasm 4 CCNF, CCNG1, CDKN1A, HMGB2
protein-containing complex 3 CDKN1A, HMGB2, MYC
intracellular membrane-bounded organelle 1 MBD1
Secreted 4 CLC, GDF15, HMGB2, IGF1
extracellular region 5 CLC, GDF15, HMGB2, IGF1, TUBB4B
Single-pass membrane protein 1 LRP1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 PLK2
nuclear membrane 1 AEN
Extracellular vesicle 1 TUBB4B
microtubule cytoskeleton 1 TUBB4B
nucleolus 5 AEN, CDKN1A, HMGB2, MKI67, MYC
Early endosome 1 LRP1
clathrin-coated pit 1 LRP1
Cytoplasm, perinuclear region 1 CCNF
Cytoplasm, cytoskeleton 1 TUBB4B
focal adhesion 2 LRP1, RPL22
microtubule 1 TUBB4B
collagen-containing extracellular matrix 1 CLC
intermediate filament 1 KRT5
nuclear speck 1 MBD1
Cytoplasm, cytoskeleton, microtubule organizing center 1 LRP1
receptor complex 1 LRP1
chromatin 4 HMGB2, MBD1, MYC, PLK2
mitotic spindle 1 TUBB4B
Chromosome 3 HMGB2, MBD1, MKI67
cytoskeleton 1 TUBB4B
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole 2 CCNF, PLK2
centriole 2 CCNF, PLK2
plasma membrane protein complex 1 LRP1
Nucleus, nucleolus 2 MKI67, MYC
spindle pole 1 PLK2
intercellular bridge 2 TUBB4B, XPA
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
nuclear envelope 1 MYC
axonemal microtubule 1 TUBB4B
microtubule organizing center 1 LRP1
Nucleus, nucleoplasm 1 MYC
Cell projection, dendrite 1 PLK2
Nucleus speckle 1 MBD1
exocytic vesicle 1 IGF1
nuclear matrix 1 MBD1
platelet alpha granule lumen 1 IGF1
kinetochore 1 PLK2
endocytic vesicle membrane 1 LRP1
RNA polymerase II transcription repressor complex 1 MYC
azurophil granule lumen 1 TUBB4B
Nucleus matrix 1 MBD1
ribonucleoprotein complex 1 RPL22
Rough endoplasmic reticulum 1 MYC
keratin filament 1 KRT5
condensed chromosome 1 HMGB2
cytosolic ribosome 1 RPL22
CRLF-CLCF1 complex 1 CLC
Golgi outpost 1 LRP1
cyclin-dependent protein kinase holoenzyme complex 3 CCNF, CCNG1, CDKN1A
ribosome 1 RPL22
Myc-Max complex 1 MYC
alphav-beta3 integrin-IGF-1-IGF1R complex 1 IGF1
insulin-like growth factor binding protein complex 1 IGF1
insulin-like growth factor ternary complex 1 IGF1
cytosolic large ribosomal subunit 1 RPL22
nucleotide-excision repair factor 1 complex 1 XPA
SCF ubiquitin ligase complex 1 CCNF
PCNA-p21 complex 1 CDKN1A
CNTFR-CLCF1 complex 1 CLC
[Low-density lipoprotein receptor-related protein 1 intracellular domain]: Cytoplasm 1 LRP1
nucleoplasmic reticulum 1 MYC


文献列表

  • Izet M Kapetanovic, Thomas L Horn, William D Johnson, Michael J Cwik, Carol J Detrisac, David L McCormick. Murine oncogenicity and pharmacokinetics studies of 9-cis-UAB30, an RXR agonist, for breast cancer chemoprevention. International journal of toxicology. 2010 Mar; 29(2):157-64. doi: 10.1177/1091581809360070. [PMID: 20335511]
  • T L Horn, M J Cwik, R L Morrissey, I Kapetanovic, J A Crowell, T D Booth, D L McCormick. Oncogenicity evaluation of resveratrol in p53(+/-) (p53 knockout) mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2007 Jan; 45(1):55-63. doi: 10.1016/j.fct.2006.07.015. [PMID: 16965847]
  • Carla E Torrey, James A Campbell, Debie J Hoivik, Richard T Miller, Jane S Allen, Peter C Mann, Krzysztof Selinger, Douglas Rickert, Paul M Savina, Michael J Santostefano. Evaluation of the carcinogenic potential of clofibrate in the p53+/- mouse. International journal of toxicology. 2005 Sep; 24(5):289-99. doi: 10.1080/10915810500210237. [PMID: 16257849]
  • Y F Sasaki, E Nishidate, Y Q Su, N Matsusaka, S Tsuda, N Susa, Y Furukawa, S Ueno. Organ-specific genotoxicity of the potent rodent bladder carcinogens o-anisidine and p-cresidine. Mutation research. 1998 Jan; 412(2):155-60. doi: 10.1016/s1383-5718(97)00183-6. [PMID: 9539969]
  • S E Dunn, F W Kari, J French, J R Leininger, G Travlos, R Wilson, J C Barrett. Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice. Cancer research. 1997 Nov; 57(21):4667-72. doi: . [PMID: 9354418]