Gene Association: PHLDA3

UniProt Search: PHLDA3 (PROTEIN_CODING)
Function Description: pleckstrin homology like domain family A member 3

found 18 associated metabolites with current gene based on the text mining result from the pubmed database.

4-(Dimethylamino)azobenzene

N,N-dimethyl-4-[(Z)-2-phenyldiazen-1-yl]aniline

C14H15N3 (225.1266)


4-(Dimethylamino)azobenzene is formerly used as a food dye, use discontinued.Methyl yellow, or C.I. 11020, is a chemical compound which may be used as a pH indicator. In aqueous solution at low pH, methyl yellow appears red. Between pH 2.9 and 4.0, methyl yellow undergoes a transition, to become yellow above pH 4.0. As "butter yellow" the agent had been used as a food additive before its toxicity was recognized (Opie EL). (Wikipedia Formerly used as a food dye, use discontinued D009676 - Noxae > D002273 - Carcinogens D004396 - Coloring Agents

   

2,4-Toluenediamine

2,4-Diaminotoluene, monohydrochloride

C7H10N2 (122.0844)


2,4-toluenediamine belongs to the family of Toluenes. These are compounds containing a benzene ring which bears a methane group. D009676 - Noxae > D002273 - Carcinogens D009676 - Noxae > D009153 - Mutagens

   

2-Methoxy-5-methylaniline

2-Methoxy-5-methylaniline

C8H11NO (137.0841)


CONFIDENCE standard compound; INTERNAL_ID 745; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5210; ORIGINAL_PRECURSOR_SCAN_NO 5208 CONFIDENCE standard compound; INTERNAL_ID 745; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5226; ORIGINAL_PRECURSOR_SCAN_NO 5223 CONFIDENCE standard compound; INTERNAL_ID 745; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5212; ORIGINAL_PRECURSOR_SCAN_NO 5211 CONFIDENCE standard compound; INTERNAL_ID 745; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5203; ORIGINAL_PRECURSOR_SCAN_NO 5201 CONFIDENCE standard compound; INTERNAL_ID 745; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5197; ORIGINAL_PRECURSOR_SCAN_NO 5194 CONFIDENCE standard compound; INTERNAL_ID 745; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5219; ORIGINAL_PRECURSOR_SCAN_NO 5218 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 1002

   

3,3'-Dimethylbenzidine

3,3-dimethyl-[1,1-biphenyl]-4,4-diamine

C14H16N2 (212.1313)


CONFIDENCE standard compound; INTERNAL_ID 2434

   

N-NITROSOMORPHOLINE

alpha-Acetoxy-N-nitrosomorpholine

C4H8N2O2 (116.0586)


CONFIDENCE standard compound; EAWAG_UCHEM_ID 3454 CONFIDENCE standard compound; INTERNAL_ID 4127 CONFIDENCE standard compound; INTERNAL_ID 8689 D009676 - Noxae > D002273 - Carcinogens D009676 - Noxae > D009153 - Mutagens

   

Allyl alcohol

2-Propenyl alcohol

C3H6O (58.0419)


Allyl alcohol is found in onion-family vegetables. Allyl alcohol is present in garlic (Allium sativum).Allyl alcohol is an organic compound with the structural formula CH2=CHCH2OH. Like many alcohols, it is a water soluble, colourless liquid, but it is more toxic than typical small alcohols. Allyl alcohol is used as a raw material for the production of glycerol, but is used as a precursor to many specialized compounds. Allyl alcohol is the smallest representative of the allylic alcohols. (Wikipedia Present in garlic (Allium sativum)

   

P-Dichlorobenzene

1,4-Dichlorobenzene (acd/name 4.0)

C6H4Cl2 (145.969)


1,4-Dichlorobenzene (p-DCB, para-dichlorobenzene) is an organic compound with the formula C6H4Cl2. This colorless solid has a strong odor. In terms of its structure, the molecule consists of two chlorine atoms substituted for hydrogen at opposing sites on a benzene ring. p-DCB is used a pesticide and a deodorant, most familiarly in mothballs in which it is a replacement for the more traditional naphthalene. p-DCB is also used as a precursor in the production of the polymer poly(p-phenylene sulfide). D010575 - Pesticides > D007306 - Insecticides D009676 - Noxae > D002273 - Carcinogens D016573 - Agrochemicals

   

2-Nitrofluorene

2-Nitro-9H-fluorene

C13H9NO2 (211.0633)


D004785 - Environmental Pollutants > D000393 - Air Pollutants D009676 - Noxae > D009153 - Mutagens

   

2,6-Dinitrotoluene

1-Methyl-2,6-dinitrobenzene

C7H6N2O4 (182.0328)


   

2,4-Diaminotoluene

2,4-Diaminotoluene

C7H10N2 (122.0844)


An aminotoluene that is para-toluidine with an additional amino group at position 2. D009676 - Noxae > D002273 - Carcinogens D009676 - Noxae > D009153 - Mutagens

   

1,4-DICHLOROBENZENE

1,4-DICHLOROBENZENE

C6H4Cl2 (145.969)


D010575 - Pesticides > D007306 - Insecticides D009676 - Noxae > D002273 - Carcinogens D016573 - Agrochemicals

   

ALLYL ALCOHOL

ALLYL ALCOHOL

C3H6O (58.0419)


A propenol in which the C=C bond connects C-2 and C-3. It is has been found in garlic (Allium sativum). Formerly used as a herbicide for the control of various grass and weed seeds.

   

N-NITROSOMORPHOLINE

N-NITROSOMORPHOLINE

C4H8N2O2 (116.0586)


D009676 - Noxae > D002273 - Carcinogens D009676 - Noxae > D009153 - Mutagens

   

Methyl Yellow

4-(Dimethylamino)azobenzene

C14H15N3 (225.1266)


D009676 - Noxae > D002273 - Carcinogens D004396 - Coloring Agents

   

Para-Cresidine

2-Methoxy-5-methylaniline

C8H11NO (137.0841)


   

2,6-DNT

2,6-DINITROTOLUENE

C7H6N2O4 (182.0328)


   

2-Nitrofluorene

2-Nitro-9H-fluorene

C13H9NO2 (211.0633)


D004785 - Environmental Pollutants > D000393 - Air Pollutants D009676 - Noxae > D009153 - Mutagens

   

3,3-dimethylbenzidine

3,3-dimethylbenzidine

C14H16N2 (212.1313)