nitroglycerin (BioDeep_00001867866)
Main id: BioDeep_00000006501
代谢物信息卡片
1,2,3-Propanetriyl trinitrate
化学式: C3H5N3O9 (227.00258000000002)
中文名称: 硝酸甘油, 硝化甘油
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(CO[N+](=O)[O-])O[N+](=O)[O-])O[N+](=O)[O-]
InChI: InChI=1S/C3H5N3O9/c7-4(8)13-1-3(15-6(11)12)2-14-5(9)10/h3H,1-2H2
描述信息
C - Cardiovascular system > C05 - Vasoprotectives > C05A - Agents for treatment of hemorrhoids and anal fissures for topical use > C05AE - Muscle relaxants
C - Cardiovascular system > C01 - Cardiac therapy > C01D - Vasodilators used in cardiac diseases > C01DA - Organic nitrates
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent
D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
D053834 - Explosive Agents
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
2 个代谢物同义名
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:28787
- KEGG: C07455
- KEGGdrug: D00515
- PubChem: 4510
- DrugBank: DB00727
- ChEMBL: CHEMBL730
- MeSH: Nitroglycerin
- CAS: 9010-02-0
- CAS: 55-63-0
- PubChem: 9658
- PDB-CCD: TNG
- NIKKAJI: J4.491A
- RefMet: Nitroglycerin
分类词条
相关代谢途径
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Min Xu, Jiayan Zhang, Zhenhua Shi, Ziyang He, Yijing Zhao, Xiaoyang Ling, Wenhua Wang, Mingjie Gong. Amelioration of nitroglycerin-induced migraine in mice via Wuzhuyu decoction: Inhibition of the MZF1/PGK1 pathway and activation of NRF2 antioxidant response.
Journal of ethnopharmacology.
2024 May; 326(?):117930. doi:
10.1016/j.jep.2024.117930. [PMID: 38373662] - Rosaria Greco, Chiara Demartini, Miriam Francavilla, Anna Maria Zanaboni, Sara Facchetti, Michela Palmisani, Valentina Franco, Cristina Tassorelli. Effects of the Dual FAAH/MAGL Inhibitor AKU-005 on Trigeminal Hyperalgesia in Male Rats.
Cells.
2024 May; 13(10):. doi:
10.3390/cells13100830. [PMID: 38786051] - Guangshuang Lu, Shaobo Xiao, Fanchao Meng, Leyi Zhang, Yan Chang, Jinjing Zhao, Nan Gao, Wenjie Su, Xinghao Guo, Yingyuan Liu, Chenhao Li, Wenjing Tang, Liping Zou, Shengyuan Yu, Ruozhuo Liu. AMPK activation attenuates central sensitization in a recurrent nitroglycerin-induced chronic migraine mouse model by promoting microglial M2-type polarization.
The journal of headache and pain.
2024 Mar; 25(1):29. doi:
10.1186/s10194-024-01739-w. [PMID: 38454376] - Hui Cai, Shuxia Chen, Dongxiao Wang. Sudden diffuse spasm of multiple coronary arteries: A case report.
Medicine.
2024 Jan; 103(2):e36889. doi:
10.1097/md.0000000000036889. [PMID: 38215100] - Takayuki Yamaji, Farina Mohamad Yusoff, Shinji Kishimoto, Masato Kajikawa, Kenichi Yoshimura, Yukiko Nakano, Chikara Goto, Takahiro Harada, Aya Mizobuchi, Shunsuke Tanigawa, Tatsuya Maruhashi, Yukihito Higashi. Association of cumulative low-density lipoprotein cholesterol exposure with vascular function.
Journal of clinical lipidology.
2023 Dec; ?(?):. doi:
10.1016/j.jacl.2023.12.006. [PMID: 38185588] - Chao Ma, Chunran Zhu, Yajun Zhang, Mei Yu, Yizhi Song, Yulong Chong, Yan Yang, Chan Zhu, Yucui Jiang, Changming Wang, Shuo Cheng, Keke Jia, Guang Yu, Jia Li, Zongxiang Tang. Gastrodin alleviates NTG-induced migraine-like pain via inhibiting succinate/HIF-1α/TRPM2 signaling pathway in trigeminal ganglion.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2023 Dec; 125(?):155266. doi:
10.1016/j.phymed.2023.155266. [PMID: 38241917] - Min Xu, Zhenhua Shi, Ziyang He, Xiaoyang Ling, Wenhua Wang, Hua Liu, Mingjie Gong. Rutaecarpine alleviates migraine in nitroglycerin-induced mice by regulating PTEN/PGK1 signaling pathway to activate NRF2 antioxidant system.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2023 Aug; 166(?):115300. doi:
10.1016/j.biopha.2023.115300. [PMID: 37557014] - Qiangyuan Tian, Xiangkong Song, Liqiang Wu, Hongyan Shi. The efficacy of glyceryl trinitrate for acute intracerebral hemorrhage: A systematic review and meta-analysis.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University.
2023 Jul; ?(?):. doi:
10.17219/acem/168430. [PMID: 37486700] - Rosaria Greco, Miriam Francavilla, Chiara Demartini, Anna Maria Zanaboni, Sara Facchetti, Michela Palmisani, Valentina Franco, Cristina Tassorelli. Activity of FAAH-Inhibitor JZP327A in an Experimental Rat Model of Migraine.
International journal of molecular sciences.
2023 Jun; 24(12):. doi:
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Journal of ethnopharmacology.
2023 Jun; ?(?):116781. doi:
10.1016/j.jep.2023.116781. [PMID: 37315643] - Bin Zhou, Cheng-Li Lin, Shinsuke Kojima, Masanori Fukushima, Chung Y Hsu. Risk factors of dementia in patients with cerebral vascular diseases based on Taiwan National Health Insurance data.
Dementia and geriatric cognitive disorders.
2023 Mar; ?(?):. doi:
10.1159/000530102. [PMID: 36948166] - Yue Yang, Ke Feng, Yuting Lei, Li Qiu, Chengjiang Liu, Guofeng Li. Comparing the efficacy and safety of different analgesic strategies after open hemorrhoidectomy: a systematic review and network meta-analysis.
International journal of colorectal disease.
2023 Jan; 38(1):4. doi:
10.1007/s00384-022-04294-5. [PMID: 36609578] - Qiping Mao, Yushun Cui, Hui Du, Jiahui Wu, Maofu Zhou, Hui Ouyang, Yuling Feng, Shiling Yang. San Pian decoction can treat nitroglycerin-induced migraine in rats by inhibiting the PI3K/AKT and MAPK signaling pathways.
Journal of ethnopharmacology.
2022 Oct; 296(?):115470. doi:
10.1016/j.jep.2022.115470. [PMID: 35738471] - Zixin Li, Luchen Shan, Pei Yu. Preventive effect of tetramethylpyrazine on nitroglycerin-tolerance in rats by improving oxidative stress and ribosome homeostasis.
Biochemical and biophysical research communications.
2022 08; 618(?):141-147. doi:
10.1016/j.bbrc.2022.06.013. [PMID: 35724458] - Rosaria Greco, Chiara Demartini, Anna Maria Zanaboni, Miriam Francavilla, Angelo Reggiani, Natalia Realini, Rita Scarpelli, Daniele Piomelli, Cristina Tassorelli. Potentiation of endocannabinoids and other lipid amides prevents hyperalgesia and inflammation in a pre-clinical model of migraine.
The journal of headache and pain.
2022 Jul; 23(1):79. doi:
10.1186/s10194-022-01449-1. [PMID: 35799128] - Elena Gerasimova, Olga Yakovleva, Daniel Enikeev, Ksenia Bogatova, Anton Hermann, Rashid Giniatullin, Guzel Sitdikova. Hyperhomocysteinemia Increases Cortical Excitability and Aggravates Mechanical Hyperalgesia and Anxiety in a Nitroglycerine-Induced Migraine Model in Rats.
Biomolecules.
2022 05; 12(5):. doi:
10.3390/biom12050735. [PMID: 35625662] - Chi Teng Vong, Yulong Chen, Zhejie Chen, Caifang Gao, Fengqing Yang, Shengpeng Wang, Yitao Wang. Classical prescription Dachuanxiong Formula delays nitroglycerin-induced pain response in migraine mice through reducing endothelin-1 level and regulating fatty acid biosynthesis.
Journal of ethnopharmacology.
2022 Apr; 288(?):114992. doi:
10.1016/j.jep.2022.114992. [PMID: 35032586] - Mohan Jc, Arun Chopra, Hiremath Js, Ajay Mahajan, Tiny Nair, Saumitra Ray, Muralitharan Tr, Ajay Pandey, Sameer Srivastava, Y Shiva Kumar, Girish Navasundi, Deepak Rajan Das, Mahesh V Abhyankar, Santosh Revankar, Pradip Mate. Experts' Consensus on Use of Long-Acting Nitroglycerine in the Management of Angina and Chronic Coronary Syndrome in India.
The Journal of the Association of Physicians of India.
2022 Mar; 70(3):11-12. doi:
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The European journal of neuroscience.
2022 02; 55(4):1015-1031. doi:
10.1111/ejn.14897. [PMID: 32639078] - Hao Chen, Xueqian Tang, Jin Li, Bangyan Hu, Wenqin Yang, Meng Zhan, Tengyun Ma, Shijun Xu. IL-17 crosses the blood-brain barrier to trigger neuroinflammation: a novel mechanism in nitroglycerin-induced chronic migraine.
The journal of headache and pain.
2022 Jan; 23(1):1. doi:
10.1186/s10194-021-01374-9. [PMID: 34979902] - Xiao Jin, Shengjie Yang, Jing Lu, Yujuan Li, Yixi Zhao, Dan Li, Xinyue Wang, Longtao Liu, Min Wu. Exploring the therapeutic mechanism of Baduanjin in the treatment of elderly stable angina pectoris based on the gut microbiota-lipid metabolism spectrum: Study protocol for a randomized controlled trial.
Frontiers in public health.
2022; 10(?):1027839. doi:
10.3389/fpubh.2022.1027839. [PMID: 36388277] - Ayesha Rahman Ahmed, Senty Vun-Sang, Mohammad Iqbal. Therapeutic role of nitroglycerin against copper-nitrilotriacetate induced hepatic and renal damage.
Human & experimental toxicology.
2022 Jan; 41(?):9603271221131312. doi:
10.1177/09603271221131312. [PMID: 36305384] - Wayne Kaesemeyer, Tatsiana Suvorava. Treating Acute Decompensated Heart Failure in Patients with COVID-19 Using Intravenous Nitroglycerin in 5\% Glutathione.
American journal of cardiovascular drugs : drugs, devices, and other interventions.
2021 Nov; 21(6):589-593. doi:
10.1007/s40256-021-00474-w. [PMID: 33748918] - Yener Yazğan, Mustafa Nazıroğlu. Involvement of TRPM2 in the Neurobiology of Experimental Migraine: Focus on Oxidative Stress and Apoptosis.
Molecular neurobiology.
2021 Nov; 58(11):5581-5601. doi:
10.1007/s12035-021-02503-w. [PMID: 34370177] - Benjamin Karfunkle, Joseph Gill, Stephanie Shirey, Richard Gordon. COVID-19 Acute Respiratory Distress Syndrome and Pulmonary Embolism: A Case Report of Nebulized Nitroglycerin and Systemic Thrombolysis For Right Ventricular Failure.
The Journal of emergency medicine.
2021 11; 61(5):e103-e107. doi:
10.1016/j.jemermed.2021.07.014. [PMID: 34479748] - A Gajos-Draus, M Duda, A Beresewicz. Exercise and nitrite prevent and Nω-nitrol-L-arginine methyl ester reproduces imbalance in the nuclear factor-κB/NADPH oxidase 2 and nuclear factor erythroid 2-related factor 2/NADPH oxidase 4/endothelial nitric oxide synthase systems in diabetes.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2021 10; 72(5):. doi:
10.26402/jpp.2021.5.03. [PMID: 35158330] - Komal Latif, Arif-Ullah Khan, Muhammad Izhar Ul Haque, Komal Naeem. Bergapten Attenuates Nitroglycerin-Induced Migraine Headaches through Inhibition of Oxidative Stress and Inflammatory Mediators.
ACS chemical neuroscience.
2021 09; 12(18):3303-3313. doi:
10.1021/acschemneuro.1c00146. [PMID: 34455773] - Roberto De Icco, Rosaria Greco, Chiara Demartini, Pietro Vergobbi, Annamaria Zanaboni, Elena Tumelero, Angelo Reggiani, Natalia Realini, Grazia Sances, Valentina Grillo, Marta Allena, Cristina Tassorelli. Spinal nociceptive sensitization and plasma palmitoylethanolamide levels during experimentally induced migraine attacks.
Pain.
2021 09; 162(9):2376-2385. doi:
10.1097/j.pain.0000000000002223. [PMID: 33587406] - Wael Talaat, Sohila ElOnsy, Reda Mohammed Keshk. Fluorescent sensing for some nitric oxide donors in dosage forms and biological matrices.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2021 Aug; 257(?):119788. doi:
10.1016/j.saa.2021.119788. [PMID: 33894636] - Gökhan Yilmaz, Yusuf Tanrikulu. Short-term Results of Platelet-Rich Plasma in the Treatment of Chronic Anal Fissure: Randomized Controlled Clinical Study.
Diseases of the colon and rectum.
2021 06; 64(6):714-723. doi:
10.1097/dcr.0000000000001903. [PMID: 33399410] - Qi Huang, Wen Ting Wang, Shi Sheng Wang, De An Pei, Xiang Qian Sui. Cardiovascular magnetic resonance image analysis and mechanism study for the changes after treatments for primary microvascular angina pectoris.
Medicine.
2021 May; 100(21):e26038. doi:
10.1097/md.0000000000026038. [PMID: 34032727] - Ersin Cagri Simsek, Cenk Sari, Murat Kucukokur, Cenk Ekmekci, Ayfer Colak, Oner Ozdogan. Endothelial dysfunction in patients with myocardial ischemia or infarction and nonobstructive coronary arteries.
Journal of clinical ultrasound : JCU.
2021 May; 49(4):334-340. doi:
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British journal of pharmacology.
2021 04; 178(7):1495-1506. doi:
10.1111/bph.15362. [PMID: 33450066] - Benjamin T Daxon, Erin Lark, Luke J Matzek, Amanda R Fields, Kyle J Haselton. Nebulized Nitroglycerin for Coronavirus Disease 2019-Associated Acute Respiratory Distress Syndrome: A Case Report.
A&A practice.
2021 Feb; 15(2):e01376. doi:
10.1213/xaa.0000000000001376. [PMID: 33560642] - Xiaodong Qiu, Zhiying Tan, Wenhao Tang, Hui Ye, Xinjian Lu. Effects of controlled hypotension with restrictive transfusion on intraoperative blood loss and systemic oxygen metabolism in elderly patients who underwent lumbar fusion.
Trials.
2021 Jan; 22(1):99. doi:
10.1186/s13063-020-05015-5. [PMID: 33509270] - Hung-Ruei Tzeng, Ming Tatt Lee, Pi-Chuan Fan, Daniel E Knutson, Tzu-Hsuan Lai, Werner Sieghart, James Cook, Lih-Chu Chiou. α6GABAA Receptor Positive Modulators Alleviate Migraine-like Grimaces in Mice via Compensating GABAergic Deficits in Trigeminal Ganglia.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics.
2021 01; 18(1):569-585. doi:
10.1007/s13311-020-00951-1. [PMID: 33111258] - Fang Lu, Wen-Jun Zhang, Shuo Zhai, Yue-Wen Sun, Qiu-Jing Chen, Xiao-Lin Yang, Chun-Feng Zhang, Chong-Zhi Wang, Chun-Su Yuan. Anti-migraine effect of wine-processed Radix scutellariae: Pharmacodynamic verification in nitroglycerin-induced rats and correlation study between compounds dissolution and the fractal dimension.
Journal of ethnopharmacology.
2020 Dec; 263(?):113131. doi:
10.1016/j.jep.2020.113131. [PMID: 32730879] - Li Zhong, Jieqin Zhuang, Zilin Jin, Yanhong Chen, Bojun Chen. Effect of Chinese medicine for promoting blood circulation on microvascular angina: A systematic review and meta-analysis.
The American journal of emergency medicine.
2020 12; 38(12):2681-2692. doi:
10.1016/j.ajem.2020.07.072. [PMID: 33046314] - Abbas Raisi, Arash Kheradmand, Ghasem Farjanikish, Farshid Davoodi, Shayan Taheri. Nitroglycerin ameliorates sperm parameters, oxidative stress and testicular injury following by testicular torsion/detorsion in male rats.
Experimental and molecular pathology.
2020 12; 117(?):104563. doi:
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International journal of dermatology.
2020 Dec; 59(12):1522-1524. doi:
10.1111/ijd.15253. [PMID: 33084032] - Shinji Kishimoto, Kenji Oki, Tatsuya Maruhashi, Masato Kajikawa, Haruki Hashimoto, Yuji Takaeko, Takahiro Harada, Takayuki Yamaji, Yiming Han, Yasuki Kihara, Kazuaki Chayama, Chikara Goto, Farina Mohamad Yusoff, Ayumu Nakashima, Yukihito Higashi. A Comparison of Adrenalectomy and Eplerenone on Vascular Function in Patients with Aldosterone-producing Adenoma.
The Journal of clinical endocrinology and metabolism.
2020 11; 105(11):. doi:
10.1210/clinem/dgaa561. [PMID: 32818224] - Daniel H Craighead, Kaitlin A Freeberg, Douglas R Seals. Vascular Endothelial Function in Midlife/Older Adults Classified According to 2017 American College of Cardiology/American Heart Association Blood Pressure Guidelines.
Journal of the American Heart Association.
2020 09; 9(17):e016625. doi:
10.1161/jaha.120.016625. [PMID: 32815446] - Darren Mullane, Martin Lenihan, Ciara Hanley, Tom Wall, Irmina Bukowska, Michael Griffin, Georgina Flood. Efficacy of Glyceryl trinitrate (GTN) to facilitate the rewarming process during cardiopulmonary bypass.
Journal of cardiothoracic surgery.
2020 Aug; 15(1):214. doi:
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Shock (Augusta, Ga.).
2020 07; 54(1):119-127. doi:
10.1097/shk.0000000000001436. [PMID: 31425404] - Jiacheng Lin, Xu Zhang, Chaotong Li, Yingyan Zhang, Hanzhi Lu, Jiwei Chen, Zeyu Li, Xuejun Yang, Zhongping Wu. Evodiamine via targeting nNOS and AMPA receptor GluA1 inhibits nitroglycerin-induced migraine-like response.
Journal of ethnopharmacology.
2020 May; 254(?):112727. doi:
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Microcirculation (New York, N.Y. : 1994).
2020 05; 27(4):e12608. doi:
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BMC anesthesiology.
2020 04; 20(1):85. doi:
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Journal of ethnopharmacology.
2020 Mar; 249(?):112437. doi:
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2020 Feb; 45(3):645-654. doi:
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Inflammation.
2020 Feb; 43(1):264-273. doi:
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Molecular and cellular biochemistry.
2019 Nov; 461(1-2):205-212. doi:
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Drug research.
2019 Oct; 69(11):612-620. doi:
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European journal of clinical pharmacology.
2019 Oct; 75(10):1361-1367. doi:
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2019 Oct; 118(?):109276. doi:
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Atherosclerosis.
2019 10; 289(?):94-100. doi:
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Clinical spine surgery.
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American family physician.
2019 08; 100(3):147-157. doi:
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Scientific reports.
2019 06; 9(1):8595. doi:
10.1038/s41598-019-45022-4. [PMID: 31197231] - Zhong-Hui Pu, Cheng Peng, Xiao-Fang Xie, Min Luo, Huan Zhu, Rui Feng, Liang Xiong. Alkaloids from the rhizomes of Ligusticum striatum exert antimigraine effects through regulating 5-HT1B receptor and c-Jun.
Journal of ethnopharmacology.
2019 Jun; 237(?):39-46. doi:
10.1016/j.jep.2019.03.026. [PMID: 30880256] - Zeina Harhous, Sally Badawi, Noelle Gallo Bona, Bruno Pillot, Lionel Augeul, Melanie Paillard, George W Booz, Emmanuelle Canet-Soulas, Michel Ovize, Mazen Kurdi, Gabriel Bidaux. Critical appraisal of STAT3 pattern in adult cardiomyocytes.
Journal of molecular and cellular cardiology.
2019 06; 131(?):91-100. doi:
10.1016/j.yjmcc.2019.04.021. [PMID: 31022374] - Thomas Duflot, Lucile Moreau-Grangé, Clothilde Roche, Michèle Iacob, Julien Wils, Isabelle Rémy-Jouet, Anne-Françoise Cailleux, Matthieu Leuillier, Sylvanie Renet, Dongyang Li, Christophe Morisseau, Fabien Lamoureux, Vincent Richard, Gaëtan Prévost, Robinson Joannidès, Jérémy Bellien. Altered bioavailability of epoxyeicosatrienoic acids is associated with conduit artery endothelial dysfunction in type 2 diabetic patients.
Cardiovascular diabetology.
2019 03; 18(1):35. doi:
10.1186/s12933-019-0843-z. [PMID: 30885203] - Ying-Hsuan Tai, Hsiang-Ling Wu, Fu-Wei Su, Kuang-Yi Chang, Cheng-Hsiung Huang, Mei-Yung Tsou, Chih-Cherng Lu. The effect of high-dose nitroglycerin on the cerebral saturation and renal function in cardiac surgery: A propensity score analysis.
Journal of the Chinese Medical Association : JCMA.
2019 Feb; 82(2):120-125. doi:
10.1097/jcma.0000000000000013. [PMID: 30839502] - Fermín López-Rivera, Hector R Cintrón Martínez, Christian Castillo LaTorre, Alexis Rivera González, Jose Gabriel Rodríguez Vélez, Vanessa Fonseca Ferrer, Omar F Méndez Meléndez, Edgar J Vázquez Vargas, Hernán A González Monroig. Treatment of Hypertensive Cardiogenic Edema with Intravenous High-Dose Nitroglycerin in a Patient Presenting with Signs of Respiratory Failure: A Case Report and Review of the Literature.
The American journal of case reports.
2019 Jan; 20(?):83-90. doi:
10.12659/ajcr.913250. [PMID: 30662059] - Jiaxiao Shi, Yulin Li, Cong Xing, Peng Peng, Hongyu Shi, Han Ding, Pengyuan Zheng, Guangzhi Ning, Shiqing Feng. Urapidil, compared to nitroglycerin, has better clinical safety in the treatment of hypertensive patients with acute heart failure: a meta-analysis.
Drug design, development and therapy.
2019; 13(?):161-172. doi:
10.2147/dddt.s185972. [PMID: 30643384] - Fereshteh Farajdokht, Gisou Mohaddes, Dariush Shanehbandi, Pouran Karimi, Shirin Babri. Ghrelin attenuated hyperalgesia induced by chronic nitroglycerin: CGRP and TRPV1 as targets for migraine management.
Cephalalgia : an international journal of headache.
2018 10; 38(11):1716-1730. doi:
10.1177/0333102417748563. [PMID: 29237283] - Albane B R Maggio, Nathalie J Farpour-Lambert, Yacine Aggoun, Katia Galan, Fabrizio Montecucco, François Mach, Maurice Beghetti. Serum cardiovascular risk biomarkers in pre-pubertal obese children.
European journal of clinical investigation.
2018 Sep; 48(9):e12995. doi:
10.1111/eci.12995. [PMID: 29992540] - Samuel L Sidharta, Timothy J Baillie, Stuart Howell, Stephen J Nicholls, Natalie Montarello, Satoshi Honda, Daisuke Shishikura, Sinny Delacroix, Susan Kim, John F Beltrame, Peter J Psaltis, Stephen G Worthley, Matthew I Worthley. Evaluation of human coronary vasodilator function predicts future coronary atheroma progression.
Heart (British Cardiac Society).
2018 09; 104(17):1439-1446. doi:
10.1136/heartjnl-2017-312579. [PMID: 29496901] - Uwe Schuehly, Surya Ayalasomayajula, Jeppe Buchbjerg, Parasar Pal, Georg Golor, Margaret F Prescott, Gangadhar Sunkara, Markus Hinder, Thomas H Langenickel. Pharmacodynamic interaction between intravenous nitroglycerin and oral sacubitril/valsartan (LCZ696) in healthy subjects.
European journal of clinical pharmacology.
2018 Sep; 74(9):1121-1130. doi:
10.1007/s00228-018-2509-2. [PMID: 29974143] - Aureliusz Kolonko, Magdalena Bartmańska, Natalia Słabiak-Błaż, Piotr Kuczera, Agata Kujawa-Szewieczek, Rafał Ficek, Aleksander J Owczarek, Jerzy Chudek, Andrzej Więcek. Arterial stiffness but not endothelial dysfunction is associated with multidrug antihypertensive therapy and nondipper blood pressure pattern in kidney transplant recipients.
Medicine.
2018 Sep; 97(36):e11870. doi:
10.1097/md.0000000000011870. [PMID: 30200072] - Stefan P Janssens, Jan Bogaert, Jaroslaw Zalewski, Attila Toth, Tom Adriaenssens, Ann Belmans, Johan Bennett, Piet Claus, Walter Desmet, Christophe Dubois, Kaatje Goetschalckx, Peter Sinnaeve, Katleen Vandenberghe, Pieter Vermeersch, Arpad Lux, Zsolt Szelid, Monika Durak, Piotr Lech, Krzysztof Zmudka, Peter Pokreisz, Pascal Vranckx, Bela Merkely, Kenneth D Bloch, Frans Van de Werf. Nitric oxide for inhalation in ST-elevation myocardial infarction (NOMI): a multicentre, double-blind, randomized controlled trial.
European heart journal.
2018 08; 39(29):2717-2725. doi:
10.1093/eurheartj/ehy232. [PMID: 29800130] - Yong-Ping Bai, Jia-Xiong Zhang, Quan Sun, Ji-Peng Zhou, Jing-Min Luo, Ling-Fang He, Xing-Chi Lin, Ling-Ping Zhu, Wan-Zhou Wu, Zhen-Yu Wang, Guo-Gang Zhang. Induction of microRNA-199 by Nitric Oxide in Endothelial Cells Is Required for Nitrovasodilator Resistance via Targeting of Prostaglandin I2 Synthase.
Circulation.
2018 07; 138(4):397-411. doi:
10.1161/circulationaha.117.029206. [PMID: 29431644] - Martin Steinmetz, Dominik Nelles, Jutta Weisser-Thomas, Christian Schaefer, Georg Nickenig, Nikos Werner. Flow-mediated dilation, nitroglycerin-mediated dilation and their ratio predict successful renal denervation in mild resistant hypertension.
Clinical research in cardiology : official journal of the German Cardiac Society.
2018 Jul; 107(7):611-615. doi:
10.1007/s00392-018-1236-0. [PMID: 29644413] - Svetlana Krasnokutsky, Aaron Garza Romero, Daisy Bang, Virginia C Pike, Binita Shah, Talia F Igel, Irina Dektiarev, Yu Guo, Judy Zhong, Stuart D Katz, Michael H Pillinger. Impaired arterial responsiveness in untreated gout patients compared with healthy non-gout controls: association with serum urate and C-reactive protein.
Clinical rheumatology.
2018 Jul; 37(7):1903-1911. doi:
10.1007/s10067-018-4029-y. [PMID: 29450849] - Roman G Kuperman, Ronald T Checkai, Michael Simini, Geoffrey I Sunahara, Jalal Hawari. Energetic contaminants inhibit plant litter decomposition in soil.
Ecotoxicology and environmental safety.
2018 May; 153(?):32-39. doi:
10.1016/j.ecoenv.2018.01.052. [PMID: 29407735] - Yana Qi, Chuan Yu, Li Tang, Sheyu Li, Xin Sun. Patient characteristics associated with treatment response in patients receiving salvianolate injection for stable angina.
Journal of evidence-based medicine.
2018 May; 11(2):83-88. doi:
10.1111/jebm.12282. [PMID: 29322692] - Zahra Sepehri Sepehri, Mohammad Masoomi, Fatemeh Ruzbehi, Zohreh Kiani, Ali Akbar Nasiri, Farhad Kohan, Mahmood Sheikh Fathollahi, Mohammad Kazemi Arababadi, Derek Kennedy, Gholamreza Asadikaram Asadikaram. Comparison of serum levels of IL-6, IL-8, TGF-β and TNF-α in coronary artery diseases, stable angina and participants with normal coronary artery.
Cellular and molecular biology (Noisy-le-Grand, France).
2018 Apr; 64(5):1-6. doi:
10.14715/cmb/2018.64.5.1. [PMID: 29729688] - Derek M Yellon, Zhenhe He, Rayomand Khambata, Amrita Ahluwalia, Sean M Davidson. The GTN patch: a simple and effective new approach to cardioprotection?.
Basic research in cardiology.
2018 04; 113(3):20. doi:
10.1007/s00395-018-0681-2. [PMID: 29666943] - Lian Yi, Qiong Wu, Nan Chen, Ge Song, Chao Wang, Qiaoge Zou, Zhongling Zhang. Valproate Plays a Protective Role against Migraine by Inhibiting Protein Kinase C Signalling in Nitroglycerin-treated Mice.
Basic & clinical pharmacology & toxicology.
2018 Mar; 122(3):310-316. doi:
10.1111/bcpt.12915. [PMID: 28990289] - Jian-Wei Gao, Xue-Min Gao, Ting Zou, Tian-Meng Zhao, Dong-Hua Wang, Zong-Gui Wu, Chang-Jie Ren, Xing Wang, Nai-Zhi Geng, Ming-Jun Zhao, Qiu-Ming Liang, Xing Feng, Bai-Song Yang, Jun-Ling Shi, Qi Hua. [Effect of Xinling Wan in treatment of stable angina pectoris: a randomized, double-blinded, placebo parallel-controlled, multicenter trial].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2018 Mar; 43(6):1268-1275. doi:
10.19540/j.cnki.cjcmm.20171226.002. [PMID: 29676139] - Choon Ok Kim, Jeongyun Song, Ji Young Min, Su Jung Park, Hye Mi Lee, Hyo-Jin Byon. A comparison of the pharmacokinetic and pharmacodynamic properties of nitroglycerin according to the composition of the administration set: A preliminary study.
Medicine.
2018 Mar; 97(9):e9829. doi:
10.1097/md.0000000000009829. [PMID: 29489681] - Adriana E Bulboacă, Sorana D Bolboacă, Ioana C Stănescu, Carmen A Sfrângeu, Alina Porfire, Lucia Tefas, Angelo C Bulboacă. The effect of intravenous administration of liposomal curcumin in addition to sumatriptan treatment in an experimental migraine model in rats.
International journal of nanomedicine.
2018; 13(?):3093-3103. doi:
10.2147/ijn.s162087. [PMID: 29872296] - Nusret Acikgoz, Ertuğrul Kurtoğlu, Julide Yagmur, Yelda Kapicioglu, Mehmet Cansel, Necip Ermis. Elevated Monocyte to High-Density Lipoprotein Cholesterol Ratio and Endothelial Dysfunction in Behçet Disease.
Angiology.
2018 Jan; 69(1):65-70. doi:
10.1177/0003319717704748. [PMID: 28421814] - Ran Liu, Huarong Xu, Xiaowen Zhang, Xiaotong Wang, Ziyue Yuan, Zhenyu Sui, Dong Wang, Kaishun Bi, Qing Li. Metabolomics Strategy Using High Resolution Mass Spectrometry Reveals Novel Biomarkers and Pain-Relief Effect of Traditional Chinese Medicine Prescription Wu-Zhu-Yu Decoction Acting on Headache Modelling Rats.
Molecules (Basel, Switzerland).
2017 Dec; 22(12):. doi:
10.3390/molecules22122110. [PMID: 29258229] - Brendan M Levac, Michael A Adams, Kyra E Pyke. The impact of an acute oral phosphate load on endothelium dependent and independent brachial artery vasodilation in healthy males.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.
2017 Dec; 42(12):1307-1315. doi:
10.1139/apnm-2017-0147. [PMID: 28806532] - Gábor Nagy-Grócz, Zsuzsanna Bohár, Annamária Fejes-Szabó, Klaudia Flóra Laborc, Eleonóra Spekker, Lilla Tar, László Vécsei, Árpád Párdutz. Nitroglycerin increases serotonin transporter expression in rat spinal cord but anandamide modulated this effect.
Journal of chemical neuroanatomy.
2017 Nov; 85(?):13-20. doi:
10.1016/j.jchemneu.2017.06.002. [PMID: 28625856] - Tal Kopel, James S Kaufman, Naomi Hamburg, John S Sampalis, Joseph A Vita, Laura M Dember. Endothelium-Dependent and -Independent Vascular Function in Advanced Chronic Kidney Disease.
Clinical journal of the American Society of Nephrology : CJASN.
2017 Oct; 12(10):1588-1594. doi:
10.2215/cjn.12811216. [PMID: 28784655] - Sudarat Satitthummanid, Noppacharn Uaprasert, Smonporn Boonyaratavej Songmuang, Ponlapat Rojnuckarin, Piyaratana Tosukhowong, Pranee Sutcharitchan, Suphot Srimahachota. Depleted nitric oxide and prostaglandin E2 levels are correlated with endothelial dysfunction in β-thalassemia/HbE patients.
International journal of hematology.
2017 Sep; 106(3):366-374. doi:
10.1007/s12185-017-2247-8. [PMID: 28474291] - Nan-Kai Wang, Yun Fu, Jung-Pan Wang, Eugene Yu-Chan Kang, An-Lun Wu, Yun-Ju Tseng, Lung-Kun Yeh, Kuan-Jen Chen, Wei-Chi Wu, Wan-Jing Ho, Chi-Chun Lai. Peripheral Vascular Endothelial Dysfunction in Central Serous Chorioretinopathy.
Investigative ophthalmology & visual science.
2017 09; 58(11):4524-4529. doi:
10.1167/iovs.17-21825. [PMID: 28877318] - A Rahman, S M Vasenwala, M Iqbal. Hepatoprotective potential of glyceryl trinitrate against chemically induced oxidative stress and hepatic injury in rats.
Human & experimental toxicology.
2017 Aug; 36(8):785-794. doi:
10.1177/0960327116665675. [PMID: 27758841] - Yuliya Lytvyn, Ronnie Har, Amy Locke, Vesta Lai, Derek Fong, Andrew Advani, Bruce A Perkins, David Z I Cherney. Renal and Vascular Effects of Uric Acid Lowering in Normouricemic Patients With Uncomplicated Type 1 Diabetes.
Diabetes.
2017 07; 66(7):1939-1949. doi:
10.2337/db17-0168. [PMID: 28408434] - Vikram S Kashyap, Ryan O Lakin, Patricia Campos, Matthew Allemang, Ann Kim, Timur P Sarac, Alfred Hausladen, Jonathan S Stamler. The LargPAD Trial: Phase IIA evaluation of l-arginine infusion in patients with peripheral arterial disease.
Journal of vascular surgery.
2017 07; 66(1):187-194. doi:
10.1016/j.jvs.2016.12.127. [PMID: 28366306] - Cheng-Long Cui, Xin He, Cui-Lan Dong, Zi-Jing Song, Jun Ji, Xue Wang, Ling Wang, Jiao-Ying Wang, Wen-Juan Du, Chong-Zhi Wang, Chun-Su Yuan, Chang-Run Guo, Chun-Feng Zhang. The enhancement mechanism of wine-processed Radix Scutellaria on NTG-induced migraine rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2017 Jul; 91(?):138-146. doi:
10.1016/j.biopha.2017.04.067. [PMID: 28456113] - Adriana J van Ballegooijen, Leila Zelnick, Andrew N Hoofnagle, Naomi M Hamburg, Cassiane Robinson-Cohen, Prabir Roy-Chaudhury, Alfred K Cheung, Yan-Ting Shiu, Ian H de Boer, Jonathan Himmelfarb, Gerald Beck, Peter B Imrey, John W Kusek, Bryan Kestenbaum. Association of Vitamin D Metabolites With Arterial Function in the Hemodialysis Fistula Maturation Study.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2017 Jun; 69(6):805-814. doi:
10.1053/j.ajkd.2017.01.049. [PMID: 28359657] - Xiao-Fan Zhang, Wen-Jun Zhang, Cui-Lan Dong, Wan-Li Hu, Yu-Yao Sun, Yarigui Bao, Chun-Feng Zhang, Chang-Run Guo, Chong-Zhi Wang, Chun-Su Yuan. Analgesia effect of baicalein against NTG-induced migraine in rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2017 Jun; 90(?):116-121. doi:
10.1016/j.biopha.2017.03.052. [PMID: 28343071] - Juthamas Khamseekaew, Sirinart Kumfu, Suwakon Wongjaikam, Sasiwan Kerdphoo, Thidarat Jaiwongkam, Somdet Srichairatanakool, Suthat Fucharoen, Siriporn C Chattipakorn, Nipon Chattipakorn. Effects of iron overload, an iron chelator and a T-Type calcium channel blocker on cardiac mitochondrial biogenesis and mitochondrial dynamics in thalassemic mice.
European journal of pharmacology.
2017 Mar; 799(?):118-127. doi:
10.1016/j.ejphar.2017.02.015. [PMID: 28192097] - Jin Wu, Dongchao Yuan, Mingqian Yang, Wei Xia, Zhe Zhang, Huiyong Zhang, Yutong Fei, Guanlin Yang. Sini decoction as an adjuvant therapy for angina pectoris: a systematic review of randomized controlled trials.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2017 02; 37(1):12-22. doi:
10.1016/s0254-6272(17)30021-3. [PMID: 29956897] - Min Hou, Qing Tang, Qiang Xue, Xiaona Zhang, Yang Liu, Sheng Yang, Liechun Chen, Xiaoyu Xu. Pharmacodynamic action and mechanism of Du Liang soft capsule, a traditional Chinese medicine capsule, on treating nitroglycerin-induced migraine.
Journal of ethnopharmacology.
2017 Jan; 195(?):231-237. doi:
10.1016/j.jep.2016.11.025. [PMID: 27866934] - Kevin P Robb, Tiziana Cotechini, Camille Allaire, Arissa Sperou, Charles H Graham. Inflammation-induced fetal growth restriction in rats is associated with increased placental HIF-1α accumulation.
PloS one.
2017; 12(4):e0175805. doi:
10.1371/journal.pone.0175805. [PMID: 28423052] - Sijin Wen, Jing Ning, Sean Collins, Donald Berry. A response-adaptive design of initial therapy for emergency department patients with heart failure.
Contemporary clinical trials.
2017 01; 52(?):46-53. doi:
10.1016/j.cct.2016.11.002. [PMID: 27838474]