Zalcitabine (BioDeep_00001867699)
Main id: BioDeep_00000001914
代谢物信息卡片
化学式: C9H13N3O3 (211.0956868)
中文名称: 2,3-二脱氧胞苷
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC(OC1CO)N2C=CC(=NC2=O)N
InChI: InChI=1S/C9H13N3O3/c10-7-3-4-12(9(14)11-7)8-2-1-6(5-13)15-8/h3-4,6,8,13H,1-2,5H2,(H2,10,11,14)/t6-,8+/m0/s1
描述信息
J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals > J05AF - Nucleoside and nucleotide reverse transcriptase inhibitors
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D018894 - Reverse Transcriptase Inhibitors
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D044966 - Anti-Retroviral Agents
C254 - Anti-Infective Agent > C281 - Antiviral Agent > C1660 - Anti-HIV Agent
D009676 - Noxae > D000963 - Antimetabolites > D015224 - Dideoxynucleosides
D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors
Zalcitabine is a potent nucleoside analogue reverse transcriptase inhibitor used in the treatment of HIV infection.
同义名列表
4 个代谢物同义名
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:10101
- KEGG: C76390
- KEGG: C07207
- KEGGdrug: D00412
- PubChem: 24066
- DrugBank: DB00943
- ChEMBL: CHEMBL853
- MeSH: Zalcitabine
- CAS: 7481-89-2
- PubChem: 9416
- NIKKAJI: J277.119E
- RefMet: Zalcitabine
- medchemexpress: HY-17392
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
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Antiviral therapy.
2004 Oct; 9(5):801-10. doi:
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. [PMID: 15535418] - Alessio Bocedi, Stefania Notaril, Pasquale Narciso, Alessandro Bolli, Mauro Fasano, Paolo Ascenzi. Binding of anti-HIV drugs to human serum albumin.
IUBMB life.
2004 Oct; 56(10):609-14. doi:
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The Journal of physiology.
2004 Aug; 558(Pt 3):807-23. doi:
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Antiviral therapy.
2004 Aug; 9(4):529-36. doi:
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Die Pharmazie.
2004 Aug; 59(8):604-7. doi:
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Hepatology (Baltimore, Md.).
2004 Feb; 39(2):311-7. doi:
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Clinical pharmacokinetics.
2004; 43(15):1071-87. doi:
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Molecular membrane biology.
2004 Jan; 21(1):1-10. doi:
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Organic & biomolecular chemistry.
2003 Nov; 1(21):3656-62. doi:
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Organic & biomolecular chemistry.
2003 Nov; 1(21):3663-9. doi:
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Antiviral therapy.
2003 Oct; 8(5):463-70. doi:
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The Journal of antimicrobial chemotherapy.
2003 Aug; 52(2):194-8. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2003 Jul; 791(1-2):137-47. doi:
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2003 Apr; 107(4):196-201. doi:
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The Cochrane database of systematic reviews.
2003; ?(4):CD002037. doi:
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2003 Jan; 10(1):50-4. doi:
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2002 Dec; 31(5):464-71. doi:
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Antimicrobial agents and chemotherapy.
2002 Dec; 46(12):3854-60. doi:
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AIDS (London, England).
2002 Nov; 16(16):2165-73. doi:
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2002 Oct; 31(2):128-36. doi:
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European journal of medical research.
2002 Aug; 7(8):341-6. doi:
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AIDS research and human retroviruses.
2002 Jul; 18(10):733-6. doi:
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2002 Jul; 30(3):271-7. doi:
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American journal of physiology. Cell physiology.
2002 Jul; 283(1):C155-68. doi:
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2002 Jun; 7(2):131-9. doi:
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Antimicrobial agents and chemotherapy.
2002 May; 46(5):1394-401. doi:
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2002 Apr; 54(1):37-45. doi:
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2002 Mar; 7(1):11-20. doi:
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2001 Dec; 52(3):281-8. doi:
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2001 Nov; 184(10):1355-7. doi:
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AIDS research and human retroviruses.
2001 Aug; 17(12):1099-105. doi:
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2001 Jul; 11(14):1897-902. doi:
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