Wortmannin (BioDeep_00000001645)

   


代谢物信息卡片


11-(acetyloxy)-1S,6bR,7,8,9aS,10,11R,11bR-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5-h]-2-benzopyran-3,6,9-trione

化学式: C23H24O8 (428.1471104)
中文名称: 渥曼青霉素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)OC1CC2(C(CCC2=O)C3=C1C4(C(OC(=O)C5=COC(=C54)C3=O)COC)C)C
InChI: InChI=1S/C23H24O8/c1-10(24)30-13-7-22(2)12(5-6-14(22)25)16-18(13)23(3)15(9-28-4)31-21(27)11-8-29-20(17(11)23)19(16)26/h8,12-13,15H,5-7,9H2,1-4H3/t12-,13+,15+,22-,23-/m0/s1

描述信息

D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D007329 - Insulin Antagonists
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C2152 - Phosphatidylinositide 3-Kinase Inhibitor
D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents
D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor
C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor
D011838 - Radiation-Sensitizing Agents

同义名列表

3 个代谢物同义名

Wortmannin; 11-(acetyloxy)-1S,6bR,7,8,9aS,10,11R,11bR-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5-h]-2-benzopyran-3,6,9-trione; LSM-1788



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Lei Yang, Liwen Jiang. The seven rice vacuolar sorting receptors localize to prevacuolar compartments. Journal of plant physiology. 2023 Dec; 291(?):154137. doi: 10.1016/j.jplph.2023.154137. [PMID: 37984048]
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  • Ting Li, Dong Chen, Houqin Liu, Yuan Tao, Xuan He, Shuya Zang, Jiaxin Li, Ling Zhang, Man Li, Ji Liu, Qin He. Spatially targeting and regulating tumor-associated macrophages using a raspberry-like micellar system sensitizes pancreatic cancer chemoimmunotherapy. Nanoscale. 2022 Sep; 14(36):13098-13112. doi: 10.1039/d2nr03053e. [PMID: 35972382]
  • Kajal Sinha, Shiv Kumar, Bindu Rawat, Rahul Singh, Rituraj Purohit, Dinesh Kumar, Yogendra Padwad. Kutkin, iridoid glycosides enriched fraction of Picrorrhiza kurroa promotes insulin sensitivity and enhances glucose uptake by activating PI3K/Akt signaling in 3T3-L1 adipocytes. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2022 Aug; 103(?):154204. doi: 10.1016/j.phymed.2022.154204. [PMID: 35671635]
  • Larissa Smulders, Rachel Altman, Carolina Briseno, Alireza Saatchi, Leslie Wallace, Maha AlSebaye, Robert V Stahelin, Nikolas Nikolaidis. Phosphatidylinositol Monophosphates Regulate the Membrane Localization of HSPA1A, a Stress-Inducible 70-kDa Heat Shock Protein. Biomolecules. 2022 06; 12(6):. doi: 10.3390/biom12060856. [PMID: 35740982]
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