Hexaconazole (BioDeep_00000001576)
natural product
代谢物信息卡片
化学式: C14H17Cl2N3O (313.0749)
中文名称: 己唑醇
谱图信息:
最多检出来源 Escherichia coli(natural_products) 19.46%
分子结构信息
SMILES: CCCCC(CN1C=NC=N1)(C2=C(C=C(C=C2)Cl)Cl)O
InChI: InChI=1S/C14H17Cl2N3O/c1-2-3-6-14(20,8-19-10-17-9-18-19)12-5-4-11(15)7-13(12)16/h4-5,7,9-10,20H,2-3,6,8H2,1H3
描述信息
CONFIDENCE standard compound; INTERNAL_ID 1269; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9950; ORIGINAL_PRECURSOR_SCAN_NO 9948
CONFIDENCE standard compound; INTERNAL_ID 1269; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9938; ORIGINAL_PRECURSOR_SCAN_NO 9937
CONFIDENCE standard compound; INTERNAL_ID 1269; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9900; ORIGINAL_PRECURSOR_SCAN_NO 9899
CONFIDENCE standard compound; INTERNAL_ID 1269; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9947; ORIGINAL_PRECURSOR_SCAN_NO 9942
CONFIDENCE standard compound; INTERNAL_ID 1269; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9912; ORIGINAL_PRECURSOR_SCAN_NO 9911
CONFIDENCE standard compound; INTERNAL_ID 1269; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9988; ORIGINAL_PRECURSOR_SCAN_NO 9986
同义名列表
数据库引用编号
19 个数据库交叉引用编号
- ChEBI: CHEBI:83711
- KEGG: C18466
- PubChem: 66461
- Metlin: METLIN72272
- ChEMBL: CHEMBL1898860
- CAS: 79983-71-4
- MoNA: CCMSLIB00001058590
- MoNA: CCMSLIB00001058875
- MoNA: CCMSLIB00001059043
- MoNA: LU126901
- MoNA: LU126905
- MoNA: LU126903
- MoNA: LU126904
- MoNA: LU126906
- MoNA: LU126902
- PMhub: MS000000792
- ChEBI: CHEBI:81766
- PubChem: 124489140
- KNApSAcK: 81766
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Dali Sun, Guofei Luo, Qinghai Zhang, Min Wang, Tianming Yang, Yao Wang, Junxiao Pang. Sub-chronic exposure to hexaconazole affects the lipid metabolism of rats through mTOR-PPAR-γ/SREBP1 signaling pathway mediated by oxidative stress.
Pesticide biochemistry and physiology.
2023 Dec; 197(?):105646. doi:
10.1016/j.pestbp.2023.105646
. [PMID: 38072521] - Na Yang, Junxiao Pang, Zhoubing Huang, Qinghai Zhang, Zelan Wang, Dali Sun. Enantioselective toxicity effect and mechanism of hexaconazole enantiomers to human breast cancer cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2023 Mar; 173(?):113612. doi:
10.1016/j.fct.2023.113612
. [PMID: 36681264] - Yue Deng, Rui Liu, Meiling Zheng, Chengfeng Cai, Jinling Diao, Zhiqiang Zhou. Hexaconazole Application Saves the Loss of Grey Mold Disease but Hinders Tomato Fruit Ripening in Healthy Plants.
Journal of agricultural and food chemistry.
2022 Apr; 70(13):3948-3957. doi:
10.1021/acs.jafc.2c00109
. [PMID: 35324179] - Dali Sun, Na Yang, Qinghai Zhang, Zelan Wang, Guofei Luo, Junxiao Pang. The discovery of combined toxicity effects and mechanisms of hexaconazole and arsenic to mice based on untargeted metabolomics.
Ecotoxicology and environmental safety.
2021 Dec; 226(?):112859. doi:
10.1016/j.ecoenv.2021.112859
. [PMID: 34624535] - Shuang Rong, Xinyi Tang, Huihui Liu, Junhu Xu, Zitong Yuan, Xinya Peng, Jinzhi Niu, Yan Wu, Lin He, Kun Qian. Synthesis of carbon dots@Fe3O4 and their photocatalytic degradation properties to hexaconazole.
NanoImpact.
2021 04; 22(?):100304. doi:
10.1016/j.impact.2021.100304
. [PMID: 35559982] - Farhatun Najat Maluin, Mohd Zobir Hussein, Nor Azah Yusof, Sharida Fakurazi, Zainol Maznah, Abu Seman Idris, Nur Hailini Zainol Hilmi, Leona Daniela Jeffery Daim. Residual analysis of chitosan-based agronanofungicides as a sustainable alternative in oil palm disease management.
Scientific reports.
2020 12; 10(1):22323. doi:
10.1038/s41598-020-79335-6
. [PMID: 33339951] - Soudamini Mohapatra, Lekha Siddamallaiah, Nagapooja Yogendraiah Matadha, Shambulinga Gadigeppa, Danish Poothotathil Raja, Veena Rao Udupi. Persistence and dissipation study of azoxystrobin, buprofezin, dinocap and hexaconazole on mango (Mangifera indica L.).
Environmental science and pollution research international.
2020 Sep; 27(26):32820-32828. doi:
10.1007/s11356-020-09557-8
. [PMID: 32519101] - Xiaokang An, Chunyan Tian, Jun Xu, Fengshou Dong, Xingang Liu, Xiaohu Wu, Yongquan Zheng. Characterization of hexaconazole-degrading strain Sphingobacterium multivorum and analysis of transcriptome for biodegradation mechanism.
The Science of the total environment.
2020 Jun; 722(?):137171. doi:
10.1016/j.scitotenv.2020.137171
. [PMID: 32213434] - Marjan Asadi, Hassan Sereshti. Magnetic amino-functionalized hollow silica-titania microsphere as an efficient sorbent for extraction of pesticides in green and roasted coffee beans.
Journal of separation science.
2020 Jun; 43(11):2115-2124. doi:
10.1002/jssc.201901135
. [PMID: 32115813] - Farhatun Najat Maluin, Mohd Zobir Hussein, Nor Azah Yusof, Sharida Fakurazi, Abu Seman Idris, Nur Hailini Zainol Hilmi, Leona Daniela Jeffery Daim. Chitosan-Based Agronanofungicides as a Sustainable Alternative in the Basal Stem Rot Disease Management.
Journal of agricultural and food chemistry.
2020 Apr; 68(15):4305-4314. doi:
10.1021/acs.jafc.9b08060
. [PMID: 32227887] - Farhatun Najat Maluin, Mohd Zobir Hussein, Nor Azah Yusof, Sharida Fakurazi, Abu Seman Idris, Nur Hailini Zainol Hilmi, Leona Daniela Jeffery Daim. Phytotoxicity of chitosan-based agronanofungicides in the vegetative growth of oil palm seedling.
PloS one.
2020; 15(4):e0231315. doi:
10.1371/journal.pone.0231315
. [PMID: 32315346] - Farhatun Najat Maluin, Mohd Zobir Hussein, Nor Azah Yusof, Sharida Fakurazi, Abu Seman Idris, Nur Hailini Zainol Hilmi, Leona Daniela Jeffery Daim. Preparation of Chitosan-Hexaconazole Nanoparticles as Fungicide Nanodelivery System for Combating Ganoderma Disease in Oil Palm.
Molecules (Basel, Switzerland).
2019 Jul; 24(13):. doi:
10.3390/molecules24132498
. [PMID: 31288497] - Ming Jia, Yao Wang, Dezhen Wang, Miaomiao Teng, Jin Yan, Sen Yan, Zhiyuan Meng, Ruisheng Li, Zhiqiang Zhou, Wentao Zhu. The effects of hexaconazole and epoxiconazole enantiomers on metabolic profile following exposure to zebrafish (Danio rerio) as well as the histopathological changes.
Chemosphere.
2019 Jul; 226(?):520-533. doi:
10.1016/j.chemosphere.2019.03.140
. [PMID: 30953897] - Mohammad Shahid, Mohd Saghir Khan. Fungicide tolerant Bradyrhizobium japonicum mitigate toxicity and enhance greengram production under hexaconazole stress.
Journal of environmental sciences (China).
2019 Apr; 78(?):92-108. doi:
10.1016/j.jes.2018.07.007
. [PMID: 30665660] - Duoduo Jiang, Lifang Duan, Runan Li, Xinglu Pan, Yan Tao, Xiaohu Wu, Jun Xu, Xingang Liu, Fengshou Dong, Yongquan Zheng. Evaluation of the safe application of copper nonylphenolsulfonate and hexaconazole in wax gourd under field conditions.
Ecotoxicology and environmental safety.
2018 Sep; 159(?):71-76. doi:
10.1016/j.ecoenv.2018.04.037
. [PMID: 29730411] - Pankaj Kumar, Sushil Ahlawat, Reena Chauhan, Anil Kumar, Ram Singh, Ashwani Kumar. In vitro and field efficacy of fungicides against sheath blight of rice and post-harvest fungicide residue in soil, husk, and brown rice using gas chromatography-tandem mass spectrometry.
Environmental monitoring and assessment.
2018 Aug; 190(9):503. doi:
10.1007/s10661-018-6897-7
. [PMID: 30088099] - Isshadiba F Mustafa, Mohd Zobir Hussein, Bullo Saifullah, Abu Seman Idris, Nur Hailini Z Hilmi, Sharida Fakurazi. Synthesis of (Hexaconazole-Zinc/Aluminum-Layered Double Hydroxide Nanocomposite) Fungicide Nanodelivery System for Controlling Ganoderma Disease in Oil Palm.
Journal of agricultural and food chemistry.
2018 Jan; 66(4):806-813. doi:
10.1021/acs.jafc.7b04222
. [PMID: 29281878] - Chao Ju, Jun Xu, Xiaohu Wu, Fengshou Dong, Xingang Liu, Chunyan Tian, Yongquan Zheng. Effects of hexaconazole application on soil microbes community and nitrogen transformations in paddy soils.
The Science of the total environment.
2017 Dec; 609(?):655-663. doi:
10.1016/j.scitotenv.2017.07.146
. [PMID: 28763662] - Yan-Hong Shi, Jin-Jing Xiao, Rong-Peng Feng, Yu-Ying Liu, Min Liao, Xiang-Wei Wu, Ri-Mao Hua, Hai-Qun Cao. Factors Affecting the Bioaccessibility and Intestinal Transport of Difenoconazole, Hexaconazole, and Spirodiclofen in Human Caco-2 Cells Following in Vitro Digestion.
Journal of agricultural and food chemistry.
2017 Oct; 65(41):9139-9146. doi:
10.1021/acs.jafc.7b02781
. [PMID: 28915046] - Jie Li, Cuiyu Sun, Nan Yu, Chen Wang, Tongtong Zhang, Huaiyu Bu. Hexaconazole-Cu complex improves the salt tolerance of Triticum aestivum seedlings.
Pesticide biochemistry and physiology.
2016 Feb; 127(?):90-4. doi:
10.1016/j.pestbp.2015.09.012
. [PMID: 26821663] - Pragyan Dubey, Amit Kumar Mishra, Ashok Kumar Singh. Comparative analyses of genotoxicity, oxidative stress and antioxidative defence system under exposure of methyl parathion and hexaconazole in barley (Hordeum vulgare L.).
Environmental science and pollution research international.
2015 Dec; 22(24):19848-59. doi:
10.1007/s11356-015-5216-x
. [PMID: 26286802] - Zainol Maznah, Muhamad Halimah, Sahid Ismail, Abu Seman Idris. Dissipation of the fungicide hexaconazole in oil palm plantation.
Environmental science and pollution research international.
2015 Dec; 22(24):19648-57. doi:
10.1007/s11356-015-5178-z
. [PMID: 26276276] - Qing Zhang, Liangliang Zhou, Yu Yang, Xiude Hua, Haiyan Shi, Minghua Wang. Study on the stereoselective degradation of three triazole fungicides in sediment.
Ecotoxicology and environmental safety.
2015 Jul; 117(?):1-6. doi:
10.1016/j.ecoenv.2015.03.014
. [PMID: 25814463] - Rajesh Kumar, Kishore Kumar Nair, Md Imteyaz Alam, Robin Gogoi, Pradeep Kumar Singh, Chitra Srivastava, Madhuban Gopal, Arunava Goswami. Development and Quality Control of Nanohexaconazole as an Effective Fungicide and Its Biosafety Studies on Soil Nitifiers.
Journal of nanoscience and nanotechnology.
2015 Feb; 15(2):1350-6. doi:
10.1166/jnn.2015.9088
. [PMID: 26353654] - Yan Wang, Chang Liu, Jie Gao, Chunwei Wang, Lili Cui, Aijun Li. Dissipation behavior of hexaconazole and kresoxim-methyl residues in ginseng and soil under field conditions.
Environmental monitoring and assessment.
2015 Jan; 187(1):4126. doi:
10.1007/s10661-014-4126-6
. [PMID: 25446716] - Runqiang Liu, Yijun Zhang, Lianyang Bai, Mingxian Huang, Jun Chen, Yuping Zhang. Synthesis of cellulose-2,3-bis(3,5-dimethylphenylcarbamate) in an ionic liquid and its chiral separation efficiency as stationary phase.
International journal of molecular sciences.
2014 Apr; 15(4):6161-8. doi:
10.3390/ijms15046161
. [PMID: 24733066] - K Sowndhararajan, S Marimuthu, S Manian. Integrated control of blister blight disease in tea using the biocontrol agent Ochrobactrum anthropi strain BMO-111 with chemical fungicides.
Journal of applied microbiology.
2013 May; 114(5):1491-9. doi:
10.1111/jam.12159
. [PMID: 23414338] - Yuanbo Li, Fengshou Dong, Xingang Liu, Jun Xu, Xiu Chen, Yongtao Han, Xuyang Liang, Yongquan Zheng. Studies of enantiomeric degradation of the triazole fungicide hexaconazole in tomato, cucumber, and field soil by chiral liquid chromatography-tandem mass spectrometry.
Chirality.
2013 Mar; 25(3):160-9. doi:
10.1002/chir.22121
. [PMID: 23335346] - Halimah Muhamad, Maznah Zainol, Ismail Sahid, Idris Abu Seman. Determination of hexaconazole in field samples of an oil palm plantation.
Drug testing and analysis.
2012 Aug; 4 Suppl 1(?):112-7. doi:
10.1002/dta.1351
. [PMID: 22851367] - Xinquan Wang, Hu Zhang, Hao Xu, Xiangyun Wang, Changxing Wu, Hongda Yang, Zhen Li, Qiang Wang. Enantioselective residue dissipation of hexaconazole in cucumber (Cucumis sativus L.), head cabbage (Brassica oleracea L. var. caulorapa DC.), and soils.
Journal of agricultural and food chemistry.
2012 Mar; 60(9):2212-8. doi:
10.1021/jf204523t
. [PMID: 22309697] - Munees Ahemad, Mohammad Saghir Khan. Effect of fungicides on plant growth promoting activities of phosphate solubilizing Pseudomonasputida isolated from mustard (Brassica compestris) rhizosphere.
Chemosphere.
2012 Mar; 86(9):945-50. doi:
10.1016/j.chemosphere.2011.11.013
. [PMID: 22133911] - Yuanbo Li, Fengshou Dong, Xingang Liu, Jun Xu, Jing Li, Zhiqiang Kong, Xiu Chen, Xuyang Liang, Yongquan Zheng. Simultaneous enantioselective determination of triazole fungicides in soil and water by chiral liquid chromatography/tandem mass spectrometry.
Journal of chromatography. A.
2012 Feb; 1224(?):51-60. doi:
10.1016/j.chroma.2011.12.044
. [PMID: 22209355] - Munees Ahemad, Mohammad Saghir Khan. Toxicological assessment of selective pesticides towards plant growth promoting activities of phosphate solubilizing Pseudomonas aeruginosa.
Acta microbiologica et immunologica Hungarica.
2011 Sep; 58(3):169-87. doi:
10.1556/amicr.58.2011.3.1
. [PMID: 21983319] - Munees Ahemad, Mohammad Saghir Khan. Ecotoxicological assessment of pesticides towards the plant growth promoting activities of Lentil (Lens esculentus)-specific Rhizobium sp. strain MRL3.
Ecotoxicology (London, England).
2011 Jun; 20(4):661-9. doi:
10.1007/s10646-011-0606-4
. [PMID: 21318390] - Mostafa Hojati, Seyed Ali Mohammad Modarres-Sanavy, Faezeh Ghanati, Mehdi Panahi. Hexaconazole induces antioxidant protection and apigenin-7-glucoside accumulation in Matricaria chamomilla plants subjected to drought stress.
Journal of plant physiology.
2011 May; 168(8):782-91. doi:
10.1016/j.jplph.2010.11.009
. [PMID: 21208683] - Munees Ahemad, Mohammad Saghir Khan. Effect of pesticides on plant growth promoting traits of greengram-symbiont, Bradyrhizobium sp. strain MRM6.
Bulletin of environmental contamination and toxicology.
2011 Apr; 86(4):384-8. doi:
10.1007/s00128-011-0231-1
. [PMID: 21359648] - Mayurika Goel, Prem Dureja, Archna Rani, Prem L Uniyal, Hartmut Laatsch. Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
Journal of agricultural and food chemistry.
2011 Mar; 59(6):2299-307. doi:
10.1021/jf1049613
. [PMID: 21351753] - Thomas D Baird, Marie E DeLorenzo. Descriptive and mechanistic toxicity of conazole fungicides using the model test alga Dunaliella tertiolecta (Chlorophyceae).
Environmental toxicology.
2010 Jun; 25(3):213-20. doi:
10.1002/tox.20493
. [PMID: 19382186] - S Navarro, J Fenoll, N Vela, E Ruiz, G Navarro. Photocatalytic degradation of eight pesticides in leaching water by use of ZnO under natural sunlight.
Journal of hazardous materials.
2009 Dec; 172(2-3):1303-10. doi:
10.1016/j.jhazmat.2009.07.137
. [PMID: 19729242] - Chinnachamy Karthika, Narayanan Nair Muraleedharan. Contribution of leaf growth on the disappearance of fungicides used on tea under South Indian agroclimatic conditions.
Journal of Zhejiang University. Science. B.
2009 Jun; 10(6):422-6. doi:
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. [PMID: 19489107] - R Gopi, C Abdul Jaleel, R Sairam, G M A Lakshmanan, M Gomathinayagam, R Panneerselvam. Differential effects of hexaconazole and paclobutrazol on biomass, electrolyte leakage, lipid peroxidation and antioxidant potential of Daucus carota L.
Colloids and surfaces. B, Biointerfaces.
2007 Nov; 60(2):180-6. doi:
10.1016/j.colsurfb.2007.06.003
. [PMID: 17644352] - Ganapathy Murugan Alagu Lakshmanan, Cheruth Abdul Jaleel, Muthiah Gomathinayagam, Rajaram Panneerselvam. Changes in antioxidant potential and sink-organ dry matter with pigment accumulation induced by hexaconazole in Plectranthus forskholii Briq.
Comptes rendus biologies.
2007 Nov; 330(11):814-20. doi:
10.1016/j.crvi.2007.08.008
. [PMID: 17923375] - Muthiah Gomathinayagam, Cheruth Abdul Jaleel, G M Alagu Lakshmanan, Rajaram Panneerselvam. Changes in carbohydrate metabolism by triazole growth regulators in cassava (Manihot esculenta Crantz); effects on tuber production and quality.
Comptes rendus biologies.
2007 Sep; 330(9):644-55. doi:
10.1016/j.crvi.2007.06.002
. [PMID: 17720581] - Tarun Kumar Chattapadhyay, Prem Dureja. Antifungal activity of 4-methyl-6-alkyl-2H-pyran-2-ones.
Journal of agricultural and food chemistry.
2006 Mar; 54(6):2129-33. doi:
10.1021/jf052792s
. [PMID: 16536586] - Olga Aguín, J Pedro Mansilla, María J Sainz. In vitro selection of an effective fungicide against Armillaria mellea and control of white root rot of grapevine in the field.
Pest management science.
2006 Mar; 62(3):223-8. doi:
10.1002/ps.1149
. [PMID: 16475239] - Qiu Xia Wang, Jing Qiu, Ping Wang, Gui Fang Jia, Peng Wang, Jun Ling Li, Zhi Qiang Zhou. Stereoselective kinetic study of hexaconazole enantiomers in the rabbit.
Chirality.
2005 May; 17(4):186-92. doi:
10.1002/chir.20152
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Pest management science.
2004 Sep; 60(9):875-80. doi:
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