Citalopram (BioDeep_00000001535)

human metabolite blood metabolite Chemicals and Drugs

代谢物信息卡片

1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile

化学式: C20H21FN2O (324.1637828)
中文名称: 西酞普兰
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
InChI: InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3

描述信息

Citalopram is an antidepressant drug used to treat depression associated with mood disorders. It is also used on occasion in the treatment of body dysmorphic disorder and anxiety; Citalopram belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs). It is sold under the brand-names Celexa (U.S., Forest Laboratories, Inc.), Cipramil, Seropram (Europe and Australia) and Ciazil (Australia); A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition; Citalopram is an antidepressant drug used to treat depression associated with mood disorders. It is also used on occasion in the treatment of body dysmorphic disorder and anxiety. Citalopram belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs).
Citalopram is an antidepressant drug used to treat depression associated with mood disorders. It is also used on occasion in the treatment of body dysmorphic disorder and anxiety; Citalopram belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs). It is sold under the brand-names Celexa (U.S., Forest Laboratories, Inc.), Cipramil, Seropram (Europe and Australia) and Ciazil (Australia); A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition; Citalopram is an antidepressant drug used to treat depression associated with mood disorders. It is also used on occasion in the treatment of body dysmorphic disorder and anxiety.
N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants > N06AB - Selective serotonin reuptake inhibitors
D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017367 - Selective Serotonin Reuptake Inhibitors
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents
C78272 - Agent Affecting Nervous System > C94725 - Selective Serotonin Reuptake Inhibitor
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors
C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent
D049990 - Membrane Transport Modulators

同义名列表

13 个代谢物同义名

1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; Citalopram hydrobromide; Escitalopram oxalate; Escitalopram; Nitalapram; Citalopram; Cytalopram; Bonitrile; Seropram; Lexapro; Citadur; recital; Celexa

数据库引用编号

17 个数据库交叉引用编号

ChEBI: CHEBI:77397
ChEBI: CHEBI:3723
KEGG: C07572
KEGGdrug: D07704
PubChem: 2771
HMDB: HMDB0005038
Metlin: METLIN1781
DrugBank: DB00215
ChEMBL: CHEMBL549
Wikipedia: Citalopram
MeSH: Citalopram
foodb: FDB023605
chemspider: 2669
CAS: 59729-33-8
PubChem: 9775
NIKKAJI: J18.081E
RefMet: Citalopram

分类词条

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(2)

Citalopram Action Pathway: Didemethylcitalopram + Oxygen + Water ⟶ Ammonia + Citalopram aldehyde + Hydrogen peroxide
Citalopram Metabolism Pathway: Didemethylcitalopram + Oxygen + Water ⟶ Ammonia + Citalopram aldehyde + Hydrogen peroxide

PharmGKB(0)

1 个相关的物种来源信息

9606 Homo sapiens: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Deniz Bozdag, Jeroen van Voorthuizen, Nikita Korpel, Sander Lentz, Hande Gurer-Orhan, Jorke H Kamstra. Dysregulation of adipogenesis and disrupted lipid metabolism by the antidepressants citalopram and sertraline. Toxicology and applied pharmacology. 2024 May; 486(?):116937. doi: 10.1016/j.taap.2024.116937. [PMID: 38643950]
Yeran Hwang, Ju-Tae Sohn. Effect of lipid emulsion on neuropsychiatric drug-induced toxicity: A narrative review. Medicine. 2024 Mar; 103(11):e37612. doi: 10.1097/md.0000000000037612. [PMID: 38489675]
Vanessa Fabienne Abegg, Miljenko Valentin Panajatovic, Riccardo Vincenzo Mancuso, Julien Arthur Allard, Urs Duthaler, Alex Odermatt, Stephan Krähenbühl, Jamal Bouitbir. Mechanisms of hepatocellular toxicity associated with the components of St. John's Wort extract hypericin and hyperforin in HepG2 and HepaRG cells. Toxicology letters. 2024 Jan; 393(?):1-13. doi: 10.1016/j.toxlet.2024.01.008. [PMID: 38219807]
Radka Kodešová, Helena Švecová, Aleš Klement, Miroslav Fér, Antonín Nikodem, Ganna Fedorova, Oleksandra Rieznyk, Martin Kočárek, Alina Sadchenko, Alica Chroňáková, Roman Grabic. Contamination of water, soil, and plants by micropollutants from reclaimed wastewater and sludge from a wastewater treatment plant. The Science of the total environment. 2023 Oct; 907(?):167965. doi: 10.1016/j.scitotenv.2023.167965. [PMID: 37866592]
Burcu Ersoy, Marie-Louise Herzog, Wen Pan, Simone Schilling, Matthias Endres, Ria Göttert, Golo D Kronenberg, Karen Gertz. The atypical antidepressant tianeptine confers neuroprotection against oxygen-glucose deprivation. European archives of psychiatry and clinical neuroscience. 2023 Sep; ?(?):. doi: 10.1007/s00406-023-01685-9. [PMID: 37653354]
Aaron L Nichols, Zack Blumenfeld, Laura Luebbert, Hailey J Knox, Anand K Muthusamy, Jonathan S Marvin, Charlene H Kim, Stephen N Grant, David P Walton, Bruce N Cohen, Rebekkah Hammar, Loren Looger, Per Artursson, Dennis A Dougherty, Henry A Lester. Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023 03; 43(13):2222-2241. doi: 10.1523/jneurosci.1519-22.2022. [PMID: 36868853]
Zhang-Jin Zhang, Shui-Yan Zhang, Xin-Jing Yang, Zong-Shi Qin, Feng-Quan Xu, Gui-Xing Jin, Xiao-Bing Hou, Yong Liu, Ji-Fu Cai, Hai-Bing Xiao, Yat Kwan Wong, Yu Zheng, Lei Shi, Jin-Niu Zhang, Yuan-Yuan Zhao, Xue Xiao, Liu-Lu Zhang, Yue Jiao, Yu Wang, Jia-Kai He, Guo-Bing Chen, Pei-Jing Rong. Transcutaneous electrical cranial-auricular acupoint stimulation versus escitalopram for mild-to-moderate depression: An assessor-blinded, randomized, non-inferiority trial. Psychiatry and clinical neurosciences. 2023 Mar; 77(3):168-177. doi: 10.1111/pcn.13512. [PMID: 36445151]
Tim Boogaerts, Maarten Quireyns, Hans De Loof, Xander Bertels, Natan Van Wichelen, Bram Pussig, Jan Saevels, Lies Lahousse, Pauline Bonmariage, Wouter Hamelinck, Bert Aertgeerts, Adrian Covaci, Alexander L N van Nuijs. Do the lockdown-imposed changes in a wastewater treatment plant catchment's socio-demographics impact longitudinal temporal trends in psychoactive pharmaceutical use?. The Science of the total environment. 2023 Feb; ?(?):162342. doi: 10.1016/j.scitotenv.2023.162342. [PMID: 36842581]
Vasiliki G Beretsou, Maria-Christina Nika, Kyriakos Manoli, Costas Michael, Qian Sui, Lian Lundy, D Michael Revitt, Nikolaos S Thomaidis, Despo Fatta-Kassinos. Multiclass target analysis of contaminants of emerging concern including transformation products, soil bioavailability assessment and retrospective screening as tools to evaluate risks associated with reclaimed water reuse. The Science of the total environment. 2022 Dec; 852(?):158391. doi: 10.1016/j.scitotenv.2022.158391. [PMID: 36049679]
Mariana N Miranda, Ana R Lado Ribeiro, Adrián M T Silva, M Fernando R Pereira. Can aged microplastics be transport vectors for organic micropollutants? - Sorption and phytotoxicity tests. The Science of the total environment. 2022 Dec; 850(?):158073. doi: 10.1016/j.scitotenv.2022.158073. [PMID: 35981591]
Somayeh Golbaz, Mirzaman Zamanzadeh, Kamyar Yaghmaeian, Ramin Nabizadeh, Nushin Rastkari, Hadi Esfahani. Occurrence and removal of psychiatric pharmaceuticals in the Tehran South Municipal Wastewater Treatment Plant. Environmental science and pollution research international. 2022 Nov; ?(?):. doi: 10.1007/s11356-022-23667-5. [PMID: 36374381]
Urwa Tariq, Masood Sadiq Butt, Imran Pasha, Muhammad Naeem Faisal. Prophylactic role of olive fruit extract against cigarette smoke-induced oxidative stress in Sprague-Dawley rats. Cell stress & chaperones. 2022 09; 27(5):545-560. doi: 10.1007/s12192-022-01291-z. [PMID: 35951259]
Hanyi Fang, Samantha Rossano, Xingxing Wang, Nabeel Nabulsi, Brian Kelley, Krista Fowles, Jim Ropchan, Stephen M Strittmatter, Richard E Carson, Yiyun Huang. Translational PET Imaging of Spinal Cord Injury with the Serotonin Transporter Tracer [11C]AFM. Molecular imaging and biology. 2022 08; 24(4):560-569. doi: 10.1007/s11307-021-01698-7. [PMID: 35020138]
Asmaa M Zaazaa, Nadia N Daoud, Ola A El-Gendy, Ahmad I Al-Shafei. Neuroprotective role of Bacopa monnieri extract in modulating depression in an experimental rat model. Journal of affective disorders. 2022 07; 308(?):229-235. doi: 10.1016/j.jad.2022.04.021. [PMID: 35413358]
M S Zastrozhin, VYu Skryabin, F Rwere, A E Petukhov, E P Pankratenko, S A Pozdniakov, V A Ivanchenko, V V Noskov, I A Zaytsev, N V Vinokurova, D S Horyaev, R V Vlasovskih, E A Bryun, D A Sychev. Influence of CYP2C19*17 Genetic Polymorphism on the Steady-State Concentration of Escitalopram in Patients with Recurrent Depressive Disorder. Psychopharmacology bulletin. 2022 06; 52(3):8-19. doi: NULL. [PMID: 35815173]
Jesús E Yepez, Jorge Juárez. Modafinil acquires reinforcing effects when combined with citalopram. Pharmacology, biochemistry, and behavior. 2022 06; 217(?):173407. doi: 10.1016/j.pbb.2022.173407. [PMID: 35605783]
Nichol Ml Wong, Ottavia Dipasquale, Federico Turkheimer, James L Findon, Robert H Wichers, Mihail Dimitrov, Clodagh M Murphy, Vladimira Stoencheva, Dene M Robertson, Declan G Murphy, Eileen Daly, Grainne M McAlonan. Differences in social brain function in autism spectrum disorder are linked to the serotonin transporter: A randomised placebo-controlled single-dose crossover trial. Journal of psychopharmacology (Oxford, England). 2022 06; 36(6):723-731. doi: 10.1177/02698811221092509. [PMID: 35491679]
Magdalene M Assimon, Patrick H Pun, Sana M Al-Khatib, M Alan Brookhart, Bradley N Gaynes, Wolfgang C Winkelmayer, Jennifer E Flythe. Proton pump inhibitors may enhance the risk of citalopram- and escitalopram-associated sudden cardiac death among patients receiving hemodialysis. Pharmacoepidemiology and drug safety. 2022 06; 31(6):670-679. doi: 10.1002/pds.5428. [PMID: 35285107]
Ángel A Islas, Thomas Scior. Allosteric Binding of MDMA to the Human Serotonin Transporter (hSERT) via Ensemble Binding Space Analysis with ΔG Calculations, Induced Fit Docking and Monte Carlo Simulations. Molecules (Basel, Switzerland). 2022 May; 27(9):. doi: 10.3390/molecules27092977. [PMID: 35566327]
Rui Zhou, Shanshan Wang, Kunze Du, Ye Shang, Jun He, Jin Li, Yaqi Yao, Yan-Xu Chang. Stereoselective enrichment and determination of citalopram enantiomers by cation-selective exhaustive injection and sweeping coupled with cyclodextrin modified electrokinetic chromatography. Journal of chromatography. A. 2022 Apr; 1669(?):462951. doi: 10.1016/j.chroma.2022.462951. [PMID: 35303575]
Mohammad-Hadi Karimi-Harandi, Mehdi Shabani-Nooshabadi, Rozhin Darabi. Simultaneous determination of citalopram and selegiline using an efficient electrochemical sensor based on ZIF-8 decorated with RGO and g-C3N4 in real samples. Analytica chimica acta. 2022 Apr; 1203(?):339662. doi: 10.1016/j.aca.2022.339662. [PMID: 35361426]
Rachel G Zsido, Eóin N Molloy, Elena Cesnaite, Gergana Zheleva, Nathalie Beinhölzl, Ulrike Scharrer, Fabian A Piecha, Ralf Regenthal, Arno Villringer, Vadim V Nikulin, Julia Sacher. One-week escitalopram intake alters the excitation-inhibition balance in the healthy female brain. Human brain mapping. 2022 04; 43(6):1868-1881. doi: 10.1002/hbm.25760. [PMID: 35064716]
Shaoyuan Li, Peijing Rong, Yu Wang, Guixing Jin, Xiaobing Hou, Suxia Li, Xue Xiao, Wei Zhou, Yue Wu, Yaping Liu, Yue Zhang, Bin Zhao, Yiting Huang, Jin Cao, Helen Chen, Sierra Hodges, Mark Vangel, Jian Kong. Comparative Effectiveness of Transcutaneous Auricular Vagus Nerve Stimulation vs Citalopram for Major Depressive Disorder: A Randomized Trial. Neuromodulation : journal of the International Neuromodulation Society. 2022 Apr; 25(3):450-460. doi: 10.1016/j.neurom.2021.10.021. [PMID: 35088753]
Fei Duan, Man-Man Li, Wei-Xia Li, Jin-Fa Tang, Zhi-Wan Wang. [Serum metabolomics of chronic obstructive pulmonary disease with lung-Qi deficiency syndrome]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2022 Apr; 47(8):2251-2256. doi: 10.19540/j.cnki.cjcmm.20211203.501. [PMID: 35531742]
Anna M Becker, Friederike Holze, Tanja Grandinetti, Aaron Klaiber, Vanja E Toedtli, Karolina E Kolaczynska, Urs Duthaler, Nimmy Varghese, Anne Eckert, Edna Grünblatt, Matthias E Liechti. Acute Effects of Psilocybin After Escitalopram or Placebo Pretreatment in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Subjects. Clinical pharmacology and therapeutics. 2022 04; 111(4):886-895. doi: 10.1002/cpt.2487. [PMID: 34743319]
Ralph Gradisch, Dániel Szöllősi, Marco Niello, Erika Lazzarin, Harald H Sitte, Thomas Stockner. Occlusion of the human serotonin transporter is mediated by serotonin-induced conformational changes in the bundle domain. The Journal of biological chemistry. 2022 03; 298(3):101613. doi: 10.1016/j.jbc.2022.101613. [PMID: 35065961]
Xiaokang Li, Jinwen Li, Yunyuan Huang, Qi Gong, Yan Fu, Yixiang Xu, Junyang Huang, Haolan You, Dong Zhang, Dan Zhang, Fei Mao, Jin Zhu, Huan Wang, Haiyan Zhang, Jian Li. The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression. European journal of medicinal chemistry. 2022 Feb; 229(?):114045. doi: 10.1016/j.ejmech.2021.114045. [PMID: 34922191]
Weiwei Xue, Tingting Fu, Shengzhe Deng, Fengyuan Yang, Jingyi Yang, Feng Zhu. Molecular Mechanism for the Allosteric Inhibition of the Human Serotonin Transporter by Antidepressant Escitalopram. ACS chemical neuroscience. 2022 02; 13(3):340-351. doi: 10.1021/acschemneuro.1c00694. [PMID: 35041375]
Anders Sørensen, Henricus G Ruhé, Klaus Munkholm. The relationship between dose and serotonin transporter occupancy of antidepressants-a systematic review. Molecular psychiatry. 2022 01; 27(1):192-201. doi: 10.1038/s41380-021-01285-w. [PMID: 34548628]
Chih-Wei Hsu, Wei-Ting Tseng, Liang-Jen Wang, Yao-Hsu Yang, Hung-Yu Kao, Pao-Yen Lin. Comparative effectiveness of antidepressants on geriatric depression: Real-world evidence from a population-based study. Journal of affective disorders. 2022 01; 296(?):609-615. doi: 10.1016/j.jad.2021.10.009. [PMID: 34655698]
Carlos Eduardo Miranda de Sousa, Noely Camila Tavares Cavalcanti Bedor, Giovana Damasceno Sousa, Guilherme Henrique Onório de Oliveira, Leila Bastos Leal, Danilo Cesar Galindo Bedor, Whocely Victor de Castro, Davi Pereira de Santana. Selective LC-MS/MS determination of citalopram enantiomers and application to a pharmacokinetic evaluation of generic and reference formulations. Biomedical chromatography : BMC. 2022 Jan; 36(1):e5237. doi: 10.1002/bmc.5237. [PMID: 34469601]
Thomas J F Angenoorth, Stevan Stankovic, Marco Niello, Marion Holy, Simon D Brandt, Harald H Sitte, Julian Maier. Interaction Profiles of Central Nervous System Active Drugs at Human Organic Cation Transporters 1-3 and Human Plasma Membrane Monoamine Transporter. International journal of molecular sciences. 2021 Nov; 22(23):. doi: 10.3390/ijms222312995. [PMID: 34884800]
Olof R Hjorth, Andreas Frick, Malin Gingnell, Johanna M Hoppe, Vanda Faria, Sara Hultberg, Iman Alaie, Kristoffer N T Månsson, Jörgen Rosén, Margareta Reis, Kurt Wahlstedt, My Jonasson, Mark Lubberink, Gunnar Antoni, Mats Fredrikson, Tomas Furmark. Expectancy effects on serotonin and dopamine transporters during SSRI treatment of social anxiety disorder: a randomized clinical trial. Translational psychiatry. 2021 11; 11(1):559. doi: 10.1038/s41398-021-01682-3. [PMID: 34732695]
Robert Suchting, Charles E Green, Constanza de Dios, Jessica Vincent, F Gerard Moeller, Scott D Lane, Joy M Schmitz. Citalopram for treatment of cocaine use disorder: A Bayesian drop-the-loser randomized clinical trial. Drug and alcohol dependence. 2021 11; 228(?):109054. doi: 10.1016/j.drugalcdep.2021.109054. [PMID: 34600245]
Tomiko Oskotsky, Ivana Maric, Alice Tang, Boris Oskotsky, Ronald J Wong, Nima Aghaeepour, Marina Sirota, David K Stevenson. Mortality Risk Among Patients With COVID-19 Prescribed Selective Serotonin Reuptake Inhibitor Antidepressants. JAMA network open. 2021 11; 4(11):e2133090. doi: 10.1001/jamanetworkopen.2021.33090. [PMID: 34779847]
Jeremiah B Joyce, Caroline W Grant, Duan Liu, Siamak MahmoudianDehkordi, Rima Kaddurah-Daouk, Michelle Skime, Joanna Biernacka, Mark A Frye, Taryn Mayes, Thomas Carmody, Paul E Croarkin, Liewei Wang, Richard Weinshilboum, William V Bobo, Madhukar H Trivedi, Arjun P Athreya. Multi-omics driven predictions of response to acute phase combination antidepressant therapy: a machine learning approach with cross-trial replication. Translational psychiatry. 2021 10; 11(1):513. doi: 10.1038/s41398-021-01632-z. [PMID: 34620827]
Lobna A Abdelwahab, Omneya O Galal, Sahar S Abd El-Rahman, Amany I El-Brairy, Mahmoud M Khattab, Aiman S El-Khatib. Targeting the Oxytocin System to Ameliorate Early Life Depressive-Like Behaviors in Maternally-Separated Rats. Biological & pharmaceutical bulletin. 2021 Oct; 44(10):1445-1457. doi: 10.1248/bpb.b21-00247. [PMID: 34349049]
Takashi Shiroyama, Kouji Fukuyama, Motohiro Okada. Distinct Effects of Escitalopram and Vortioxetine on Astroglial L-Glutamate Release Associated with Connexin43. International journal of molecular sciences. 2021 Sep; 22(18):. doi: 10.3390/ijms221810013. [PMID: 34576176]
Lyndsey L Anderson, Peter T Doohan, Lachlan Oldfield, Richard C Kevin, Jonathon C Arnold, Maximus Berger, G Paul Amminger, Iain S McGregor. Citalopram and Cannabidiol: In Vitro and In Vivo Evidence of Pharmacokinetic Interactions Relevant to the Treatment of Anxiety Disorders in Young People. Journal of clinical psychopharmacology. 2021 Sep; 41(5):525-533. doi: 10.1097/jcp.0000000000001427. [PMID: 34121064]
Line Skute Bråten, Tore Haslemo, Marin M Jukic, Maxim Ivanov, Magnus Ingelman-Sundberg, Espen Molden, Marianne Kristiansen Kringen. A Novel CYP2C-Haplotype Associated With Ultrarapid Metabolism of Escitalopram. Clinical pharmacology and therapeutics. 2021 09; 110(3):786-793. doi: 10.1002/cpt.2233. [PMID: 33759177]
Gwenn S Smith, Hiroto Kuwabara, Neda F Gould, Najilla Nassery, Alena Savonenko, Jin Hui Joo, Kristin L Bigos, Michael Kraut, James Brasic, Daniel P Holt, Andrew W Hall, William B Mathews, Robert F Dannals, Ayon Nandi, Clifford I Workman. Molecular imaging of the serotonin transporter availability and occupancy by antidepressant treatment in late-life depression. Neuropharmacology. 2021 08; 194(?):108447. doi: 10.1016/j.neuropharm.2021.108447. [PMID: 33450276]
Eóin N Molloy, Rachel G Zsido, Fabian A Piecha, Nathalie Beinhölzl, Ulrike Scharrer, Gergana Zheleva, Ralf Regenthal, Bernhard Sehm, Vadim V Nikulin, Harald E Möller, Arno Villringer, Julia Sacher, Karsten Mueller. Decreased thalamo-cortico connectivity during an implicit sequence motor learning task and 7 days escitalopram intake. Scientific reports. 2021 07; 11(1):15060. doi: 10.1038/s41598-021-94009-7. [PMID: 34301974]
Yang Shen, Xiao Yang, Gaofei Li, Jiayu Gao, Ying Liang. The change of gut microbiota in MDD patients under SSRIs treatment. Scientific reports. 2021 07; 11(1):14918. doi: 10.1038/s41598-021-94481-1. [PMID: 34290352]
Merve Sarıkaya, Halil Ibrahim Ulusoy, Ummugulsum Morgul, Songül Ulusoy, Angela Tartaglia, Erkan Yılmaz, Mustafa Soylak, Marcello Locatelli, Abuzar Kabir. Sensitive determination of Fluoxetine and Citalopram antidepressants in urine and wastewater samples by liquid chromatography coupled with photodiode array detector. Journal of chromatography. A. 2021 Jul; 1648(?):462215. doi: 10.1016/j.chroma.2021.462215. [PMID: 34000593]
Zhongxia Shen, Feng Wang, Lijun Cui, Lie Ren, Xiujuan Hong, Yonggui Yuan, Xinhua Shen. Higher baseline serum adiponectin predicts better treatment remission in patients with generalized anxiety disorder treated with escitalopram. Annals of palliative medicine. 2021 07; 10(7):7634-7643. doi: 10.21037/apm-21-1542. [PMID: 34353051]
Gao Tu, Tingting Fu, Fengyuan Yang, Jingyi Yang, Zhao Zhang, Xiaojun Yao, Weiwei Xue, Feng Zhu. Understanding the Polypharmacological Profiles of Triple Reuptake Inhibitors by Molecular Simulation. ACS chemical neuroscience. 2021 06; 12(11):2013-2026. doi: 10.1021/acschemneuro.1c00127. [PMID: 33977725]
Marina Sagud, Matea Nikolac Perkovic, Anja Dvojkovic, Nenad Jaksic, Bjanka Vuksan-Cusa, Maja Zivkovic, Zorana Kusevic, Alma Mihaljevic-Peles, Nela Pivac. Distinct association of plasma BDNF concentration and cognitive function in depressed patients treated with vortioxetine or escitalopram. Psychopharmacology. 2021 Jun; 238(6):1575-1584. doi: 10.1007/s00213-021-05790-2. [PMID: 33560444]
Pierre Baumann, Gilles Bertschy, Fritz Ramseier, Rico Nil. Plasma Concentrations and Cardiovascular Effects of Citalopram Enantiomers After Oral Versus Infusion Citalopram Therapy in Dextromethorphan-Mephenytoin-Phenotyped Patients With Major Depression. Therapeutic drug monitoring. 2021 06; 43(3):436-442. doi: 10.1097/ftd.0000000000000824. [PMID: 33060488]
Eóin N Molloy, Karsten Mueller, Nathalie Beinhölzl, Maria Blöchl, Fabian A Piecha, André Pampel, Christopher J Steele, Ulrike Scharrer, Gergana Zheleva, Ralf Regenthal, Bernhard Sehm, Vadim V Nikulin, Harald E Möller, Arno Villringer, Julia Sacher. Modulation of premotor cortex response to sequence motor learning during escitalopram intake. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2021 06; 41(6):1449-1462. doi: 10.1177/0271678x20965161. [PMID: 33148103]
Jiajia Duan, Yu Huang, Xunmin Tan, Tingjia Chai, Jing Wu, Hanping Zhang, Yifan Li, Xi Hu, Peng Zheng, Ping Ji, Libo Zhao, Deyu Yang, Liang Fang, Jinlin Song, Peng Xie. Characterization of gut microbiome in mice model of depression with divergent response to escitalopram treatment. Translational psychiatry. 2021 05; 11(1):303. doi: 10.1038/s41398-021-01428-1. [PMID: 34016954]
Or Burstein, Noam Simon, Yaarit Simchon-Tenenbaum, Moshe Rehavi, Motty Franko, Alon Shamir, Ravid Doron. Moderation of the transgenerational transference of antenatal stress-induced anxiety. Translational psychiatry. 2021 05; 11(1):268. doi: 10.1038/s41398-021-01383-x. [PMID: 33947833]
Nida Naz, Saeeda Nadir Ali, Amtul Qayoom, Sajid Iqbal, Shumaila Akram. Rapid and sensitive method for simultaneous determination of citalopram with antihistamines by liquid chromatography. Pakistan journal of pharmaceutical sciences. 2021 May; 34(3):835-841. doi: . [PMID: 34602404]
Anna Colombo, Francesca Giordano, Federica Giorgetti, Ilaria Di Bernardo, Monica F Bosi, Alberto Varinelli, Rita Cafaro, Paola Pileri, Irene Cetin, Emilio Clementi, Caterina A Viganò, Bernardo Dell'Osso. Correlation between pharmacokinetics and pharmacogenetics of Selective Serotonin Reuptake Inhibitors and Selective Serotonin and Noradrenaline Reuptake Inhibitors and maternal and neonatal outcomes: Results from a naturalistic study in patients with affective disorders. Human psychopharmacology. 2021 05; 36(3):e2772. doi: 10.1002/hup.2772. [PMID: 33253437]
Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
Yun Kim, Anhye Kim, Jae-Yong Chung. Population pharmacokinetic/pharmacodynamic modeling of delayed effect of escitalopram-induced QT prolongation. Journal of affective disorders. 2021 04; 285(?):120-126. doi: 10.1016/j.jad.2021.02.048. [PMID: 33647579]
Waqas Aslam, Carla R Lamb, Nadia Ali. Torsades de pointes in SARS-CoV-2 (COVID-19) pneumonia: medicine reconciliation and careful monitoring of QTc interval may help prevent cardiac complications. BMJ case reports. 2021 Mar; 14(3):. doi: 10.1136/bcr-2020-239963. [PMID: 33762277]
Siamak MahmoudianDehkordi, Ahmed T Ahmed, Sudeepa Bhattacharyya, Xianlin Han, Rebecca A Baillie, Matthias Arnold, Michelle K Skime, Lisa St John-Williams, M Arthur Moseley, J Will Thompson, Gregory Louie, Patricio Riva-Posse, W Edward Craighead, William McDonald, Ranga Krishnan, A John Rush, Mark A Frye, Boadie W Dunlop, Richard M Weinshilboum, Rima Kaddurah-Daouk. Alterations in acylcarnitines, amines, and lipids inform about the mechanism of action of citalopram/escitalopram in major depression. Translational psychiatry. 2021 03; 11(1):153. doi: 10.1038/s41398-020-01097-6. [PMID: 33654056]
Lorena Henn, Natália C Zanta, Carlos Eduardo N Girardi, Deborah Suchecki. Chronic Escitalopram Treatment Does Not Alter the Effects of Neonatal Stress on Hippocampal BDNF Levels, 5-HT1A Expression and Emotional Behaviour of Male and Female Adolescent Rats. Molecular neurobiology. 2021 Mar; 58(3):926-943. doi: 10.1007/s12035-020-02164-1. [PMID: 33063280]
Zolfaghar Aladaghlo, Siamak Javanbakht, Ali Reza Fakhari, Ahmad Shaabani. Gelatin microsphere coated Fe3O4@graphene quantum dots nanoparticles as a novel magnetic sorbent for ultrasound-assisted dispersive magnetic solid-phase extraction of tricyclic antidepressants in biological samples. Mikrochimica acta. 2021 02; 188(3):73. doi: 10.1007/s00604-021-04727-y. [PMID: 33550423]
Muhammad Shoaib, Edoardo Giacopuzzi, Oliver Pain, Chiara Fabbri, Chiara Magri, Alessandra Minelli, Cathryn M Lewis, Massimo Gennarelli. Investigating an in silico approach for prioritizing antidepressant drug prescription based on drug-induced expression profiles and predicted gene expression. The pharmacogenomics journal. 2021 02; 21(1):85-93. doi: 10.1038/s41397-020-00186-5. [PMID: 32943772]
Ahmed M Abdel-Raoof, Mohamed A Hasan, Ahmed W Madkour, Ashraf Abdel-Fattah, Maya S Eissa. Simultaneous determination of citalopram and tadalafil by the second derivative synchronous fluorescence method in biological fluids; application of Box-Behnken optimization design. Luminescence : the journal of biological and chemical luminescence. 2021 Feb; 36(1):57-65. doi: 10.1002/bio.3913. [PMID: 32678940]
Mahboobeh Shirazi, Mohamad Naser Jalalian, Masoumeh Abed, Marjan Ghaemi. The Effectiveness of Melissa Officinalis L. versus Citalopram on Quality of Life of Menopausal Women with Sleep Disorder: A Randomized Double-Blind Clinical Trial. Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia. 2021 Feb; 43(2):126-130. doi: 10.1055/s-0040-1721857. [PMID: 33465795]
Motohiro Okada, Ryusuke Matsumoto, Yoshimasa Yamamoto, Kouji Fukuyama. Effects of Subchronic Administrations of Vortioxetine, Lurasidone, and Escitalopram on Thalamocortical Glutamatergic Transmission Associated with Serotonin 5-HT7 Receptor. International journal of molecular sciences. 2021 Jan; 22(3):. doi: 10.3390/ijms22031351. [PMID: 33572981]
Jan Engelmann, Stefanie Wagner, Andreas Solheid, David P Herzog, Nadine Dreimüller, Marianne B Müller, André Tadić, Christoph Hiemke, Klaus Lieb. Tolerability of High-Dose Venlafaxine After Switch From Escitalopram in Nonresponding Patients With Major Depressive Disorder. Journal of clinical psychopharmacology. 2021 Jan; 41(1):62-66. doi: 10.1097/jcp.0000000000001312. [PMID: 33208708]
Lindsey A Sjaarda, Jeannie G Radoc, Kerry S Flannagan, Sunni L Mumford, Keewan Kim, Neil J Perkins, Robert M Silver, Enrique F Schisterman. Urinary selective serotonin reuptake inhibitors across critical windows of pregnancy establishment: a prospective cohort study of fecundability and pregnancy loss. Fertility and sterility. 2020 12; 114(6):1278-1287. doi: 10.1016/j.fertnstert.2020.06.037. [PMID: 33066974]
Alain Braillon. Serotonin transporter gene and escitalopram: depressing medical science. European journal of clinical pharmacology. 2020 11; 76(11):1621-1622. doi: 10.1007/s00228-020-02945-6. [PMID: 32591942]
Yi-Fan Shao, An-Qi Zhang, Tian-Jiao Chen, Hai-Bei Li, Zheng-Shan Chen, Jing Yin, Dong Yang, Dan-Yang Shi, Yong-Bing Liang, Chun-Yan Cheng, Rong Tan, Dong-Liang Sun, Jun-Wen Li, Min Jin. [Simultaneous determination of three antidepressant drugs in feces by HLPC-MS]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 2020 Nov; 36(6):668-672. doi: 10.12047/j.cjap.6173.2020.139. [PMID: 33719279]
Aleksandr Bregin, Maria Kaare, Toomas Jagomäe, Karina Karis, Katyayani Singh, Karita Laugus, Jürgen Innos, Este Leidmaa, Indrek Heinla, Tanel Visnapuu, Eva-Maria Oja, Kadri Kõiv, Kersti Lilleväli, Jaanus Harro, Mari-Anne Philips, Eero Vasar. Expression and impact of Lsamp neural adhesion molecule in the serotonergic neurotransmission system. Pharmacology, biochemistry, and behavior. 2020 11; 198(?):173017. doi: 10.1016/j.pbb.2020.173017. [PMID: 32828972]
Mohamed Saleh Elgawish, Mohamed A Ali, Moftah A Moustafa, Sameh M Hafeez. Toxicity Profile, Pharmacokinetic, and Drug-Drug Interaction Study of Citalopram and Sertraline Following Oral Delivery in Rat: An LC-MS/MS Method for the Simultaneous Determination in Plasma. Chemical research in toxicology. 2020 10; 33(10):2584-2592. doi: 10.1021/acs.chemrestox.0c00199. [PMID: 32957789]
G G Audley, P Frankenfeld, S Dlamini, P Raubenheimer, J Hoare, L Cairncross, R Van den Berg, M V Gule, G Calligaro. Prolonged treatment of COVID-19 pneumonia with high-flow nasal oxygen: A story of oxygen and resilience. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 2020 10; 110(12):1168-1171. doi: 10.7196/samj.2020.v110i12.15325. [PMID: 33403959]
Hisayuki Erabi, Go Okada, Chiyo Shibasaki, Daiki Setoyama, Dongchon Kang, Masahiro Takamura, Atsuo Yoshino, Manabu Fuchikami, Akiko Kurata, Takahiro A Kato, Shigeto Yamawaki, Yasumasa Okamoto. Kynurenic acid is a potential overlapped biomarker between diagnosis and treatment response for depression from metabolome analysis. Scientific reports. 2020 10; 10(1):16822. doi: 10.1038/s41598-020-73918-z. [PMID: 33033336]
Chia-Yu Chiu, Amara Sarwal, Rehan Azhar Munir, Michael Widjaja, Amna Khalid, Rajan Khanna. Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Induced by Long-Term Use of Citalopram and Short-Term Use of Naproxen. The American journal of case reports. 2020 Sep; 21(?):e926561. doi: 10.12659/ajcr.926561. [PMID: 32946431]
Toktam Sadat Firoozeei, Majid Barekatain, Mehrdad Karimi, Arman Zargaran, Shahin Akhondzadeh, Hossein Rezaeizadeh. Lavender and dodder combined herbal syrup versus citalopram in major depressive disorder with anxious distress: A double-blind randomized trial. Journal of integrative medicine. 2020 Sep; 18(5):409-415. doi: 10.1016/j.joim.2020.06.002. [PMID: 32739466]
Claudia Bartels, Michael Belz, Jonathan Vogelgsang, Philipp Hessmann, Jens Bohlken, Jens Wiltfang, Karel Kostev. To Be Continued? Long-Term Treatment Effects of Antidepressant Drug Classes and Individual Antidepressants on the Risk of Developing Dementia: A German Case-Control Study. The Journal of clinical psychiatry. 2020 08; 81(5):. doi: 10.4088/jcp.19m13205. [PMID: 32857931]
Jeffrey R Strawn, Jeffrey A Mills, Heidi Schroeder, Sarah A Mossman, Sara T Varney, Laura B Ramsey, Ethan A Poweleit, Zeruesenay Desta, Kim Cecil, Melissa P DelBello. Escitalopram in Adolescents With Generalized Anxiety Disorder: A Double-Blind, Randomized, Placebo-Controlled Study. The Journal of clinical psychiatry. 2020 08; 81(5):. doi: 10.4088/jcp.20m13396. [PMID: 32857933]
Wafa F S Badulla, Arın G Dal Poçan, Zeki Atkoşar, Göksel Arlı. Capillary Electrophoresis Method for Determination of Escitalopram Oxalate in Urine Samples and Different Dosage Forms. Journal of chromatographic science. 2020 Aug; 58(8):759-769. doi: 10.1093/chromsci/bmaa036. [PMID: 32685979]
Hui-Rong Guo, Bai-Ling Huang, Ya-Li Wang, Yan-Yan Zhang, Quan-Gang Ma, Pei-Pei Lv, Yu-Ming Ren. Effect of Escitalopram on Serum GDNF and BDNF Levels and 5-HT Level of Brain Tissue of Obsessive-Compulsive Disorder Rats. Cellular and molecular neurobiology. 2020 Aug; 40(6):991-997. doi: 10.1007/s10571-020-00788-4. [PMID: 31927718]
Etienne Weisskopf, Monia Guidi, Céline J Fischer, Myriam Bickle Graz, Etienne Beaufils, Kim An Nguyen, Mathilde Morisod Harari, Sylvie Rouiller, Sophie Rothenburger, Pascal Gaucherand, Behrouz Kassai-Koupai, Cristina Borradori Tolsa, Manuella Epiney, Jean-François Tolsa, Yvan Vial, Jean-Michel Hascoët, Olivier Claris, Chin B Eap, Alice Panchaud, Chantal Csajka. A population pharmacokinetic model for escitalopram and its major metabolite in depressive patients during the perinatal period: Prediction of infant drug exposure through breast milk. British journal of clinical pharmacology. 2020 08; 86(8):1642-1653. doi: 10.1111/bcp.14278. [PMID: 32162723]
Jens Teichert, James B Rowe, Karen D Ersche, Nikolina Skandali, Julia Sacher, Achim Aigner, Ralf Regenthal. Determination of atomoxetine or escitalopram in human plasma by HPLC: Applications in neuroscience research studies . International journal of clinical pharmacology and therapeutics. 2020 Aug; 58(8):426-438. doi: 10.5414/cp203705. [PMID: 32449675]
Rui Lima, Susana Monteiro, Eduardo D Gomes, Natália L Vasconcelos, Rita Assunção-Silva, Mónica Morais, António J Salgado, Nuno A Silva. Citalopram Administration Does Not Promote Function or Histological Recovery after Spinal Cord Injury. International journal of molecular sciences. 2020 Jul; 21(14):. doi: 10.3390/ijms21145062. [PMID: 32709070]
Julio Rodríguez-Lavado, Carlos Gallardo-Garrido, Michael Mallea, Victor Bustos, Rodrigo Osorio, Martín Hödar-Salazar, Hery Chung, Ramiro Araya-Maturana, Marcos Lorca, C David Pessoa-Mahana, Jaime Mella-Raipán, Claudio Saitz, Pablo Jaque, Miguel Reyes-Parada, Patricio Iturriaga-Vásquez, Hernán Pessoa-Mahana. Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease. European journal of medicinal chemistry. 2020 Jul; 198(?):112368. doi: 10.1016/j.ejmech.2020.112368. [PMID: 32388114]
Yu Sun, Wayne Drevets, Gustavo Turecki, Qingqin S Li. The relationship between plasma serotonin and kynurenine pathway metabolite levels and the treatment response to escitalopram and desvenlafaxine. Brain, behavior, and immunity. 2020 07; 87(?):404-412. doi: 10.1016/j.bbi.2020.01.011. [PMID: 31978524]
Stephen Murata, Michael Murphy, Debra Hoppensteadt, Jawed Fareed, Amanda Welborn, Angelos Halaris. Effects of adjunctive inflammatory modulation on IL-1β in treatment resistant bipolar depression. Brain, behavior, and immunity. 2020 07; 87(?):369-376. doi: 10.1016/j.bbi.2020.01.004. [PMID: 31923551]
N A Uvais. Psychological Impact of the COVID-19 Pandemic Among the Elderly: A Case Series From India. The primary care companion for CNS disorders. 2020 06; 22(4):. doi: 10.4088/pcc.20com02675. [PMID: 32589829]
S K L Quah, L McIver, A C Roberts, A M Santangelo. Trait Anxiety Mediated by Amygdala Serotonin Transporter in the Common Marmoset. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2020 06; 40(24):4739-4749. doi: 10.1523/jneurosci.2930-19.2020. [PMID: 32393533]
Evelien Zoons, Marina A J Tijssen, Yasmine E M Dreissen, Marenka Smit, Jan Booij. The Effect of Escitalopram on Central Serotonergic and Dopaminergic Systems in Patients with Cervical Dystonia, and Its Relationship with Clinical Treatment Effects: A Double-Blind Placebo-Controlled Trial. Biomolecules. 2020 06; 10(6):. doi: 10.3390/biom10060880. [PMID: 32521736]
Tatiyana Mandal, Laxminarayana Kurady Bairy, Podila Satya Venkata Narasimha Sharma. Association between functional polymorphisms in serotonin transporter gene (SLC6A4) and escitalopram treatment response in depressive patients in a South Indian population. European journal of clinical pharmacology. 2020 Jun; 76(6):807-814. doi: 10.1007/s00228-020-02866-4. [PMID: 32253447]
Merve Demirbugen Oz, Bora Baskak, Zuhal Uckun, Nazan Yuce Artun, Hatice Ozdemir, Tugba Kizil Ozel, Halise Devrimci Ozguven, H Sinan Suzen. Association between serotonin 2A receptor (HTR2A), serotonin transporter (SLC6A4) and brain-derived neurotrophic factor (BDNF) gene polymorphisms and citalopram/sertraline induced sexual dysfunction in MDD patients. The pharmacogenomics journal. 2020 06; 20(3):443-450. doi: 10.1038/s41397-019-0127-8. [PMID: 31792367]
Bichu Cheng, Johannes Morstein, Lucy Kate Ladefoged, Jannick Bang Maesen, Birgit Schiøtt, Steffen Sinning, Dirk Trauner. A Photoswitchable Inhibitor of the Human Serotonin Transporter. ACS chemical neuroscience. 2020 05; 11(9):1231-1237. doi: 10.1021/acschemneuro.9b00521. [PMID: 32275382]
Viviane de Sousa Tomaz, Adriano José Maia Chaves Filho, Rafaela Carneiro Cordeiro, Paloma Marinho Jucá, Michelle Verde Ramo Soares, Poliana Noronha Barroso, Larissa Maria Frota Cristino, Wei Jiang, Antônio Lúcio Teixeira, David F de Lucena, Danielle S Macedo. Antidepressants of different classes cause distinct behavioral and brain pro- and anti-inflammatory changes in mice submitted to an inflammatory model of depression. Journal of affective disorders. 2020 05; 268(?):188-200. doi: 10.1016/j.jad.2020.03.022. [PMID: 32174477]
Xuemei Wu, Hongfei Zhang, Mohammad Kowser Miah, Steve N Caritis, Raman Venkataramanan. Physiologically Based Pharmacokinetic Approach Can Successfully Predict Pharmacokinetics of Citalopram in Different Patient Populations. Journal of clinical pharmacology. 2020 04; 60(4):477-488. doi: 10.1002/jcph.1541. [PMID: 31750550]
Andre R Brunoni, Angel Carracedo, Olalla M Amigo, Ana L Pellicer, Leda Talib, Andre F Carvalho, Paulo A Lotufo, Isabela M Benseñor, Wagner Gattaz, Carolina Cappi. Association of BDNF, HTR2A, TPH1, SLC6A4, and COMT polymorphisms with tDCS and escitalopram efficacy: ancillary analysis of a double-blind, placebo-controlled trial. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). 2020 Apr; 42(2):128-135. doi: 10.1590/1516-4446-2019-0620. [PMID: 31721892]
Per Plenge, Ara M Abramyan, Gunnar Sørensen, Arne Mørk, Pia Weikop, Ulrik Gether, Benny Bang-Andersen, Lei Shi, Claus J Loland. The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter. Nature communications. 2020 03; 11(1):1491. doi: 10.1038/s41467-020-15292-y. [PMID: 32198394]
Jung Lee, Kyung Hwa Lee, Seong Hae Kim, Ji Youn Han, Soon-Beom Hong, Soo-Churl Cho, Jae-Won Kim, David Brent. Early changes of serum BDNF and SSRI response in adolescents with major depressive disorder. Journal of affective disorders. 2020 03; 265(?):325-332. doi: 10.1016/j.jad.2020.01.045. [PMID: 32090756]
Zsombor Szoke-Kovacs, Csaba More, Rita Szoke-Kovacs, Endre Mathe, Ede Frecska. Selective Inhibition of the Serotonin Transporter in the Treatment of Depression: Sertraline, Fluoxetine and Citalopram. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. 2020 Mar; 22(1):4-15. doi: . [PMID: 32329748]
Sisi Qin, Andy R Eugene, Duan Liu, Lingxin Zhang, Drew Neavin, Joanna M Biernacka, Jia Yu, Richard M Weinshilboum, Liewei Wang. Dual Roles for the TSPYL Family in Mediating Serotonin Transport and the Metabolism of Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. Clinical pharmacology and therapeutics. 2020 03; 107(3):662-670. doi: 10.1002/cpt.1692. [PMID: 31628858]
Edvaldo Vasconcelos Soares Maciel, Ana Lúcia de Toffoli, Jussara da Silva Alves, Fernando Mauro Lanças. Multidimensional Liquid Chromatography Employing a Graphene Oxide Capillary Column as the First Dimension: Determination of Antidepressant and Antiepileptic Drugs in Urine. Molecules (Basel, Switzerland). 2020 Feb; 25(5):. doi: 10.3390/molecules25051092. [PMID: 32121435]
Wenlu Pan, Kexin Lyu, Hongzheng Zhang, Cuixian Li, Peng Chen, Ming Ying, Fangyi Chen, Jie Tang. Attenuation of auditory mismatch negativity in serotonin transporter knockout mice with anxiety-related behaviors. Behavioural brain research. 2020 02; 379(?):112387. doi: 10.1016/j.bbr.2019.112387. [PMID: 31783087]
Monica Feliz R Castillo, Arielle Cohen, David Edberg, Debra Hoppensteadt, Jawed Fareed, Brendan Martin, Angelos Halaris. Vascular endothelial growth factor in bipolar depression: A potential biomarker for diagnosis and treatment outcome prediction. Psychiatry research. 2020 02; 284(?):112781. doi: 10.1016/j.psychres.2020.112781. [PMID: 31986357]