Fluroxypyr (BioDeep_00000001157)

   


代谢物信息卡片


Fluroxypyr

化学式: C7H5Cl2FN2O3 (253.9661)
中文名称: 氯氟吡氧乙酸
谱图信息: 最多检出来源 Rattus norvegicus(plant) 10%

分子结构信息

SMILES: C(C(=O)O)OC1=NC(=C(C(=C1Cl)N)Cl)F
InChI: InChI=1S/C7H5Cl2FN2O3/c8-3-5(11)4(9)7(12-6(3)10)15-1-2(13)14/h1H2,(H2,11,12)(H,13,14)

描述信息

D010575 - Pesticides > D006540 - Herbicides
D016573 - Agrochemicals
CONFIDENCE standard compound; EAWAG_UCHEM_ID 134
CONFIDENCE standard compound; INTERNAL_ID 56; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3625; ORIGINAL_PRECURSOR_SCAN_NO 3623
CONFIDENCE standard compound; INTERNAL_ID 56; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3620; ORIGINAL_PRECURSOR_SCAN_NO 3616
CONFIDENCE standard compound; INTERNAL_ID 56; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3623; ORIGINAL_PRECURSOR_SCAN_NO 3619
CONFIDENCE standard compound; INTERNAL_ID 56; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3622; ORIGINAL_PRECURSOR_SCAN_NO 3618

同义名列表

3 个代谢物同义名

Fluroxypyr; Fluroxypyr; Fluroxypyr



数据库引用编号

45 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ALS2, ARHGAP45, CAT, GNA12, HPGDS, MX1, MX2, PGP
Peripheral membrane protein 2 CYP1B1, MX1
Endoplasmic reticulum membrane 2 CYP1B1, MX1
Nucleus 3 ALS2, MX1, MX2
cytosol 6 ALS2, ARHGAP45, CAT, HPGDS, MX1, MX2
dendrite 1 ALS2
centrosome 1 ALS2
nucleoplasm 3 ATP2B1, HPGDS, RRS1
Cell membrane 2 ATP2B1, GNA12
Lipid-anchor 1 GNA12
lamellipodium 1 ALS2
ruffle membrane 1 ARHGAP45
Multi-pass membrane protein 1 ATP2B1
Synapse 1 ATP2B1
glutamatergic synapse 2 ALS2, ATP2B1
growth cone 1 ALS2
neuronal cell body 1 GNA12
presynaptic membrane 1 ATP2B1
plasma membrane 4 ARHGAP45, ATP2B1, BCHE, GNA12
synaptic vesicle membrane 1 ATP2B1
Membrane 6 ARHGAP45, ATP2B1, CAT, CYP1B1, MX1, MX2
basolateral plasma membrane 1 ATP2B1
extracellular exosome 2 ATP2B1, CAT
endoplasmic reticulum 1 RRS1
extracellular space 2 BCHE, PNLIP
perinuclear region of cytoplasm 1 MX1
mitochondrion 2 CAT, CYP1B1
protein-containing complex 2 ALS2, CAT
intracellular membrane-bounded organelle 5 ALS2, ATP2B1, CAT, CYP1B1, HPGDS
Microsome membrane 1 CYP1B1
postsynaptic density 1 ALS2
Secreted 2 BCHE, PNLIP
extracellular region 4 ARHGAP45, BCHE, CAT, PNLIP
mitochondrial matrix 1 CAT
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
nuclear membrane 1 MX1
dendritic spine 1 ALS2
nucleolus 1 RRS1
Early endosome 1 ALS2
vesicle 1 ALS2
Cell projection, ruffle membrane 1 ARHGAP45
Cytoplasm, perinuclear region 1 MX1
focal adhesion 2 CAT, GNA12
microtubule 2 MX1, MX2
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
lateral plasma membrane 2 ATP2B1, GNA12
ruffle 1 ALS2
neuron projection 1 GNA12
cell projection 1 ATP2B1
brush border membrane 1 GNA12
blood microparticle 1 BCHE
Basolateral cell membrane 1 ATP2B1
Nucleus, nuclear pore complex 1 MX2
nuclear pore 1 MX2
heterotrimeric G-protein complex 1 GNA12
Presynaptic cell membrane 1 ATP2B1
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 ARHGAP45, CAT
endoplasmic reticulum lumen 1 BCHE
preribosome, large subunit precursor 1 RRS1
azurophil granule lumen 1 ARHGAP45
immunological synapse 1 ATP2B1
nuclear envelope lumen 1 BCHE
condensed nuclear chromosome 1 RRS1
[Isoform 2]: Cytoplasm 1 MX1
Lateral cell membrane 1 GNA12
catalase complex 1 CAT
photoreceptor ribbon synapse 1 ATP2B1


文献列表

  • Sherry LeClere, Chenxi Wu, Philip Westra, R Douglas Sammons. Cross-resistance to dicamba, 2,4-D, and fluroxypyr in Kochia scoparia is endowed by a mutation in an AUX/IAA gene. Proceedings of the National Academy of Sciences of the United States of America. 2018 03; 115(13):E2911-E2920. doi: 10.1073/pnas.1712372115. [PMID: 29531066]
  • Alison Connolly, Kate Jones, Karen S Galea, Ioannis Basinas, Laura Kenny, Padraic McGowan, Marie Coggins. Exposure assessment using human biomonitoring for glyphosate and fluroxypyr users in amenity horticulture. International journal of hygiene and environmental health. 2017 08; 220(6):1064-1073. doi: 10.1016/j.ijheh.2017.06.008. [PMID: 28668341]
  • Nannan Pang, Yu Cui, Jiye Hu. Weather dependent dynamics of the herbicides florasulam, carfentrazone-ethyl, fluroxypyr-meptyl and fluroxypyr in wheat fields through field studies and computational simulation. Chemosphere. 2016 Dec; 165(?):320-328. doi: 10.1016/j.chemosphere.2016.09.026. [PMID: 27664521]
  • Vipan Kumar, Prashant Jha. Differences in Germination, Growth, and Fecundity Characteristics of Dicamba-Fluroxypyr-Resistant and Susceptible Kochia scoparia. PloS one. 2016; 11(8):e0161533. doi: 10.1371/journal.pone.0161533. [PMID: 27537419]
  • Lizhen Han, Degang Zhao, Cuicui Li. Isolation and 2,4-D-degrading characteristics of Cupriavidus campinensis BJ71. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]. 2015 Jun; 46(2):433-41. doi: 10.1590/s1517-838246220140211. [PMID: 26273258]
  • S Mohr, J Schott, L Hoenemann, M Feibicke. Glyceria maxima as new test species for the EU risk assessment for herbicides: a microcosm study. Ecotoxicology (London, England). 2015 Mar; 24(2):309-20. doi: 10.1007/s10646-014-1379-3. [PMID: 25380672]
  • Fabrice Marquet, Jean-Paul Payan, Dominique Beydon, Ludivine Wathier, Marie-Christine Grandclaude, Elisabeth Ferrari. In vivo and ex vivo percutaneous absorption of [14C]-bisphenol A in rats: a possible extrapolation to human absorption?. Archives of toxicology. 2011 Sep; 85(9):1035-43. doi: 10.1007/s00204-011-0651-z. [PMID: 21287149]
  • Xinyuan Xu, Zhigang Shen, Jinling Diao, Ping Zhang, Jiazhen Jiang, Zhiqiang Zhou. Stereoselective metabolism of the herbicide fluroxypyr methylheptyl ester in rabbits. Chirality. 2011 Jul; 23(6):472-8. doi: 10.1002/chir.20949. [PMID: 21462271]
  • Lei Wang, Jun Xu, Pengyue Zhao, Canping Pan. Dissipation and residues of fluroxypyr-meptyl in rice and environment. Bulletin of environmental contamination and toxicology. 2011 Apr; 86(4):449-53. doi: 10.1007/s00128-011-0218-y. [PMID: 21340457]
  • Guo Lin Wu, Jing Cui, Ling Tao, Hong Yang. Fluroxypyr triggers oxidative damage by producing superoxide and hydrogen peroxide in rice (Oryza sativa). Ecotoxicology (London, England). 2010 Jan; 19(1):124-32. doi: 10.1007/s10646-009-0396-0. [PMID: 19644752]
  • Halimah B Muhamad, Tan Yew Ai, Ismail B Sahid. Determination of the herbicide fluroxypyr in oil matrices. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2008 Feb; 43(2):134-40. doi: 10.1080/03601230701795072. [PMID: 18246505]
  • Chase Metzger, Rick Boydston, Holly Ferguson, Martin M Williams, Richard Zack, Doug Walsh. Interactions between population density of the Colorado potato beetle, Leptinotarsa decemlineata, and herbicide rate for suppression of solanaceous weeds. Journal of insect science (Online). 2008; 8(?):1-10. doi: 10.1673/031.008.3801. [PMID: 20298117]
  • M Kah, C D Brown. Changes in pesticide adsorption with time at high soil to solution ratios. Chemosphere. 2007 Jul; 68(7):1335-43. doi: 10.1016/j.chemosphere.2007.01.024. [PMID: 17320149]
  • S Vickery, P F Dodds. Incorporation of xenobiotic carboxylic acids into lipids by cultured 3T3-L1 adipocytes. Xenobiotica; the fate of foreign compounds in biological systems. 2004 Nov; 34(11-12):1025-42. doi: 10.1080/02772240400015248. [PMID: 15801546]
  • G Rijckaert, D Lepiece. Study of the selectivity of PRIMSTAR (fluroxypyr + florasulam) in two key grass species (FESRU & LOLPE) grown for seed production. Communications in agricultural and applied biological sciences. 2003; 68(4 Pt A):381-90. doi: . [PMID: 15149133]