Bis(2-ethylhexyl) phthalate (BioDeep_00000001128)

 

Secondary id: BioDeep_00000001135, BioDeep_00000399859, BioDeep_00000415898

human metabolite blood metabolite Exogenous Industrial Pollutants


代谢物信息卡片


1,2-Benzenedicarboxylic acid bis(2-ethylhexyl) ester

化学式: C24H38O4 (390.277)
中文名称: 邻苯二甲酸二辛酯
谱图信息: 最多检出来源 Homo sapiens(blood) 37.55%

Reviewed

Last reviewed on 2024-10-11.

Cite this Page

Bis(2-ethylhexyl) phthalate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/bis(2-ethylhexyl)_phthalate (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000001128). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: c1ccc(c(c1)C(=O)OC[C@@H](CCCC)CC)C(=O)OC[C@@H](CCCC)CC
InChI: InChI=1S/C24H38O4/c1-5-9-13-19(7-3)17-27-23(25)21-15-11-12-16-22(21)24(26)28-18-20(8-4)14-10-6-2/h11-12,15-16,19-20H,5-10,13-14,17-18H2,1-4H3

描述信息

Di(2-ethylhexyl) phthlate (DEHP) is a manufactured chemical that is commonly added to plastics to make them flexible. DEHP is a colorless liquid with almost no odor. DEHP is present in plastic products such as wall coverings, tablecloths, floor tiles, furniture upholstery, shower curtains, garden hoses, swimming pool liners, rainwear, baby pants, dolls, some toys, shoes, automobile upholstery and tops, packaging film and sheets, sheathing for wire and cable, medical tubing, and blood storage bags.

Di(2-ethylhexyl) phthalate is a colorless to pale yellow oily liquid. Nearly odorless. (USCG, 1999)

Bis(2-ethylhexyl) phthalate is a phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid. It has a role as an apoptosis inhibitor, an androstane receptor agonist and a plasticiser. It is a phthalate ester and a diester.

Dioctyl phthalate. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=8033-53-2 (retrieved 2024-10-11) (CAS RN: 117-81-7). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

同义名列表

43 个代谢物同义名

1,2-Benzenedicarboxylic acid bis(2-ethylhexyl) ester; 1,2-Benzenedicarboxylate bis(2-ethylhexyl) ester; 1,2-bis(2-ethylhexyl) benzene-1,2-dicarboxylate; Phthalic acid bis(2-ethylhexyl) ester; Phthalic acid di(2-ethylhexyl) ester; Di(2-ethylhexyl)orthophthalic acid; Bis(2-ethylhexyl) O-phthalic acid; Phthalate bis(2-ethylhexyl) ester; Phthalate di(2-ethylhexyl) ester; Di(2-ethylhexyl)phthalate (DEHP); Di(2-ethylhexyl) O-phthalic acid; Bis(2-ethylhexyl)phthalic acid; Di(2-ethylhexyl)orthophthalate; Di(2-ethylhexyl)phthalic acid; Bis(2-ethylhexyl) O-phthalate; Bis(ethylhexyl) phthalic acid; Di(ethylhexyl) phthalic acid; Di(2-ethylhexyl) O-phthalate; Bis(2-ethylhexyl) phthalate; di(2-ethylhexyl) phthalate; 2-Ethylhexyl phthalic acid; Bis(2-ethylhexyl)phthalate; Di-iso-octyl phthalic acid; Di-sec-octyl phthalic acid; Diethylhexyl phthalic acid; Bis(ethylhexyl) phthalate; Di(ethylhexyl) phthalate; Di-2-ethylhexylphthalate; Di 2 ethylhexylphthalate; Phthalate, diethylhexyl; Diethylhexyl phthalate; Di-sec-octyl phthalate; 2-Ethylhexyl phthalate; Di-iso-octyl phthalate; Dioctyl phthalic acid; Octyl phthalic acid; Phthalate, dioctyl; Dioctyl phthalate; Octyl phthalate; etalon; DEHP; Ergoplast FDO; ESBO-D 82



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ABCB1, ALB, CYP1A1, MTOR, NR1I3, PGR, PTGS2, TSHB
Peripheral membrane protein 4 CYP11A1, CYP1A1, MTOR, PTGS2
Endoplasmic reticulum membrane 5 CYP19A1, CYP1A1, MTOR, PTGS2, STAR
Mitochondrion membrane 1 CYP11A1
Nucleus 5 ALB, MTOR, NR1I3, PGR, PPARA
cytosol 7 ACOX1, ALB, LEP, LIPE, MTOR, NR1I3, PGR
dendrite 1 MTOR
phagocytic vesicle 1 MTOR
centrosome 1 ALB
nucleoplasm 4 MTOR, NR1I3, PGR, PPARA
Cell membrane 3 ABCB1, LIPE, STAR
Cytoplasmic side 1 MTOR
Multi-pass membrane protein 3 ABCB1, CYP19A1, TM2D1
Golgi apparatus membrane 1 MTOR
cell surface 1 ABCB1
Golgi apparatus 1 ALB
Golgi membrane 1 MTOR
lysosomal membrane 1 MTOR
mitochondrial inner membrane 2 CYP11A1, CYP1A1
neuronal cell body 1 KISS1
Cytoplasm, cytosol 1 LIPE
Lysosome 1 MTOR
plasma membrane 4 ABCB1, PGR, STAR, TM2D1
Membrane 7 ABCB1, ACOX1, CYP11A1, CYP19A1, LIPE, MTOR, TM2D1
apical plasma membrane 2 ABCB1, KISS1
caveola 2 LIPE, PTGS2
extracellular exosome 3 ABCB1, ALB, SHBG
Lysosome membrane 1 MTOR
endoplasmic reticulum 3 ALB, CYP19A1, PTGS2
extracellular space 6 ALB, AMH, INSL3, KISS1, LEP, TSHB
perinuclear region of cytoplasm 1 INSL3
mitochondrion 3 CYP11A1, CYP1A1, STAR
protein-containing complex 2 ALB, PTGS2
intracellular membrane-bounded organelle 1 CYP1A1
Microsome membrane 4 CYP19A1, CYP1A1, MTOR, PTGS2
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 1 STAR
Secreted 6 ALB, AMH, INSL3, LEP, SHBG, TSHB
extracellular region 7 ALB, AMH, INSL3, KISS1, LEP, SHBG, TSHB
Mitochondrion outer membrane 1 MTOR
mitochondrial outer membrane 2 MTOR, PGR
mitochondrial matrix 2 CYP11A1, STAR
anchoring junction 1 ALB
Apical cell membrane 1 ABCB1
Mitochondrion inner membrane 2 CYP11A1, CYP1A1
Cytoplasm, cytoskeleton 1 NR1I3
Peroxisome 1 ACOX1
peroxisomal matrix 1 ACOX1
peroxisomal membrane 1 ACOX1
Nucleus, PML body 1 MTOR
PML body 1 MTOR
mitochondrial intermembrane space 1 STAR
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
ciliary basal body 1 ALB
chromatin 3 NR1I3, PGR, PPARA
cytoskeleton 1 NR1I3
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
nuclear envelope 1 MTOR
Endomembrane system 1 MTOR
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
endoplasmic reticulum lumen 2 ALB, PTGS2
platelet alpha granule lumen 1 ALB
external side of apical plasma membrane 1 ABCB1
Cytoplasmic vesicle, phagosome 1 MTOR
[Isoform 4]: Mitochondrion outer membrane 1 PGR
ciliary transition fiber 1 ALB


文献列表

  • Yu Hao, Xuan'en Tian, Fengmei Yan, Xiuqin Wang, Jing Huang, Ling Li. Effect of MEHP on testosterone synthesis via Sirt1/Foxo1/Rab7 signaling pathway inhibition of lipophagy in TM3 cells. Ecotoxicology and environmental safety. 2024 Jun; 277(?):116394. doi: 10.1016/j.ecoenv.2024.116394. [PMID: 38663197]
  • Kai Li, Yiping Zhang, Ludi Li, Kanglong Cui, Yingzi Li, Chunying Li, Yufei Dai, Wusheng Xiao, Qi Wang. Identification of sensitive endpoints for the assessment of phthalates-induced reproductive and developmental toxicity: A literature mining study. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024 Jun; 188(?):114686. doi: 10.1016/j.fct.2024.114686. [PMID: 38663762]
  • Xiaowen Sun, Xue Zhang, Zhi Li, Tan Wang, Jie Zeng, Yongxuan Liu, Zhe Li, Lin Li. Efficient remediation of di-(2-ethylhexyl) phthalate and plant-growth promotion with the application of a phosphate-solubilizing compound microbial agent. The Science of the total environment. 2024 May; 926(?):171904. doi: 10.1016/j.scitotenv.2024.171904. [PMID: 38527548]
  • Shucong Chen, Hang Liu, Yulian Sun, Shuxian Li, Yixuan Shi, Zhipeng Cheng, Hongkai Zhu, Hongwen Sun. Phthalate Biomarkers Composition in Relation to Fatty Liver: Evidence from Epidemiologic and in vivo studies. The Science of the total environment. 2024 May; 924(?):171607. doi: 10.1016/j.scitotenv.2024.171607. [PMID: 38461993]
  • Jiten Singh, Ashok Jangra, Dinesh Kumar. Recent advances in toxicological research of di-(2-ethylhexyl)-phthalate: Focus on endoplasmic reticulum stress pathway. Chemosphere. 2024 May; 356(?):141922. doi: 10.1016/j.chemosphere.2024.141922. [PMID: 38593956]
  • Gül Kaplan, Merih Beler, Ismail Ünal, Atakan Karagöz, Gizem Eğilmezer, Ünsal Veli Üstündağ, Derya Cansız, A Ata Alturfan, Ebru Emekli-Alturfan. Diethylhexyl phthalate exposure amplifies oxidant and inflammatory response in fetal hyperglycemia model predisposing insulin resistance in zebrafish embryos. Toxicology and industrial health. 2024 May; 40(5):232-243. doi: 10.1177/07482337241238475. [PMID: 38467557]
  • Xianxu Li, Shichang Hu, Nan Jiang, Xiangfeng Yao, Can Wang, Qian Wang, Zhongkang Yang, Jun Wang. Biotoxicity responses of zebrafish in environmentally relevant concentration of di (2-ethylhexyl) phthalate. Environmental toxicology and pharmacology. 2024 Apr; 107(?):104423. doi: 10.1016/j.etap.2024.104423. [PMID: 38521434]
  • Yu Zhu, Xiang-Yu Ma, Ling-Ge Cui, Ya-Ru Xu, Chen-Xi Li, Milton Talukder, Xue-Nan Li, Jin-Long Li. Di (2-ethylhexyl) phthalate induced lipophagy-related renal ferroptosis in quail (Coturnix japonica). The Science of the total environment. 2024 Apr; 919(?):170724. doi: 10.1016/j.scitotenv.2024.170724. [PMID: 38325449]
  • Yun Bo Zhang, Jiang Li Li, Jie Tian, Xiao Lin Na. Effect of Maternal DEHP Exposure on Lipid Metabolism in Adult Male Rats and the Antagonistic Effect of Genistein. Biomedical and environmental sciences : BES. 2024 Mar; 37(3):315-319. doi: 10.3967/bes2024.034. [PMID: 38582995]
  • Xia Wang, Dinggang Li, Xiangqin Zheng, Yifan Hong, Jie Zhao, Wei Deng, Mingxin Wang, Lianju Shen, Chunlan Long, Guanghui Wei, Shengde Wu. Di-(2-ethylhexyl) phthalate induces ferroptosis in prepubertal mouse testes via the lipid metabolism pathway. Environmental toxicology. 2024 Mar; 39(3):1747-1758. doi: 10.1002/tox.24065. [PMID: 38050670]
  • Xiaoping Liang, Jiehua Liang, Shengqi Zhang, Haowei Yan, Tiangang Luan. Di-2-ethylhexyl phthalate disrupts hepatic lipid metabolism in obese mice by activating the LXR/SREBP-1c and PPAR-α signaling pathways. The Science of the total environment. 2024 Mar; 914(?):169919. doi: 10.1016/j.scitotenv.2024.169919. [PMID: 38199361]
  • Yu-Shun Lu, Zheng-Bo Liu, Yan-Yang Xu, Ji-Yue Sha, Di Qu, Yin-Shi Sun. Uptake and accumulation of di(2-ethylhexyl) phthalate (DEHP) in a soil-ginseng system and toxicological mechanisms on ginseng (Panax ginseng C.A. Meyer). The Science of the total environment. 2024 Mar; 914(?):170040. doi: 10.1016/j.scitotenv.2024.170040. [PMID: 38215853]
  • Jawad Ali Shah, Saif Ullah, Deyun Chen, Jianping Wu. Di-(2-ethylhexyl) phthalate (DEHP) contamination suppressed soil microbial biomass carbon and mitigated CO2 emissions against the background of alfalfa from different soils. Ecotoxicology and environmental safety. 2024 Mar; 272(?):116073. doi: 10.1016/j.ecoenv.2024.116073. [PMID: 38335580]
  • Yiyun Liu, Naima Hamid, Rakia Manzoor, Bao-Fu Zhang, Yan-Ling Liao, Jin-Xia Wang, De-Sheng Pei. PPARβ/δ-ANGPTL4 axis mediates the promotion of mono-2-ethylhexyl phthalic acid on MYCN-amplified neuroblastoma development. The Science of the total environment. 2024 Feb; 912(?):168949. doi: 10.1016/j.scitotenv.2023.168949. [PMID: 38042186]
  • Kajal Gaur, Himanshi Varshney, Iqra Subhan, Javeria Fatima, Smita Jyoti, Yasir Hasan Siddique. Evaluation of Bis(2-ethylhexyl) phthalate toxicity on the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024 Feb; 184(?):114425. doi: 10.1016/j.fct.2023.114425. [PMID: 38160779]
  • Kévin Bernal, Charbel Touma, Béatrice Le-Grand, Sophie Rose, Selenay Degerli, Valentine Genêt, Dominique Lagadic-Gossmann, Xavier Coumoul, Corinne Martin-Chouly, Sophie Langouët, Etienne B Blanc. Assessment of endocrine disruptor impacts on lipid metabolism in a fatty acid-supplemented HepaRG human hepatic cell line. Chemosphere. 2024 Feb; 349(?):140883. doi: 10.1016/j.chemosphere.2023.140883. [PMID: 38092172]
  • Yang Yang, Yue Tao, Rongyi Yang, Xiaodong Yi, Guanyu Zhong, Yanyan Gu, Ying Zhang. Ca2+ homeostasis imbalance induced by Pparg: A key factor in di (2-ethylhexyl) phthalate (DEHP)-induced cardiac dysfunction in zebrafish larvae. The Science of the total environment. 2024 Jan; ?(?):170436. doi: 10.1016/j.scitotenv.2024.170436. [PMID: 38281650]
  • Sean M Harris, Anthony L Su, John F Dou, Rita Loch-Caruso, Elana R Elkin, Sammy Jaber, Kelly M Bakulski. Placental cell conditioned media modifies hematopoietic stem cell transcriptome invitro. Placenta. 2024 Jan; 145(?):117-125. doi: 10.1016/j.placenta.2023.12.016. [PMID: 38128222]
  • Fulya Dal Yöntem, Sinem Ayaz, Şeyma Bulut, Ebru Hacıosmanoğlu Aldoğan, Müfide Aydoğan Ahbab. Endoplasmic reticulum stress and pro-inflammatory responses induced by phthalate metabolites monoethylhexyl phthalate and monobutyl phthalate in 1.1B4 pancreatic beta cells. Toxicology. 2024 Jan; 501(?):153695. doi: 10.1016/j.tox.2023.153695. [PMID: 38048874]
  • Hung-Yuan Su, Ching-Shu Lai, Kuo-Hsin Lee, Yu-Wei Chiang, Chia-Chi Chen, Ping-Chi Hsu. Prenatal exposure to low-dose di-(2-ethylhexyl) phthalate (DEHP) induces potentially hepatic lipid accumulation and fibrotic changes in rat offspring. Ecotoxicology and environmental safety. 2024 Jan; 269(?):115776. doi: 10.1016/j.ecoenv.2023.115776. [PMID: 38056127]
  • Hao Cai, Ke Li, Yilin Yin, Xiaotong Ni, Shiwen Xu. Quercetin alleviates DEHP exposure-induced pyroptosis and cytokine expression changes in grass carp L8824 cell line by inhibiting ROS/MAPK/NF-κB pathway. Fish & shellfish immunology. 2023 Dec; 143(?):109223. doi: 10.1016/j.fsi.2023.109223. [PMID: 37972744]
  • Hao-Ran Wang, Mu-Zi Li, Jia-Gen Cui, Hao Zhang, Yi Zhao, Jin-Long Li. Lycopene Prevents Phthalate-Induced Cognitive Impairment via Modulating Ferroptosis. Journal of agricultural and food chemistry. 2023 Nov; 71(44):16727-16738. doi: 10.1021/acs.jafc.3c04801. [PMID: 37871231]
  • Minling Gao, Linsen Bai, Ling Xiao, Hongchang Peng, Qiaoting Chen, Weiwen Qiu, Zhengguo Song. Micro (nano)plastics and phthalate esters drive endophytic bacteria alteration and inhibit wheat root growth. The Science of the total environment. 2023 Oct; ?(?):167734. doi: 10.1016/j.scitotenv.2023.167734. [PMID: 37827310]
  • Hongping Liao, Dandan Gao, Chunmiao Kong, Muhammad Junaid, Ye Li, Xikun Chen, Qingzhi Zheng, Guanglong Chen, Jun Wang. Trophic transfer of nanoplastics and di(2-ethylhexyl) phthalate in a freshwater food chain (Chlorella Pyrenoidosa-Daphnia magna-Micropterus salmoides) induced disturbance of lipid metabolism in fish. Journal of hazardous materials. 2023 Oct; 459(?):132294. doi: 10.1016/j.jhazmat.2023.132294. [PMID: 37591169]
  • Heng Shi, Xinhai Zhao, Peng Qin, Xianling Zhou, Sisi Liu, Chuanchuan Sun, Qiuyu Cao, Shiping Zhu, Shengyun Sun. Green tea polyphenols alleviate kidney injury induced by di(2-ethylhexyl) phthalate in mice. American journal of nephrology. 2023 Sep; ?(?):. doi: 10.1159/000534106. [PMID: 37734331]
  • Heng Shi, Xin-Hai Zhao, Qin Peng, Xian-Ling Zhou, Si-Si Liu, Chuan-Chuan Sun, Qiu-Yu Cao, Shi-Ping Zhu, Sheng-Yun Sun. Green tea polyphenols alleviate di-(2-ethylhexyl) phthalate-induced liver injury in mice. World journal of gastroenterology. 2023 Sep; 29(34):5054-5074. doi: 10.3748/wjg.v29.i34.5054. [PMID: 37753369]
  • Shivani Popli Goyal, Chakkaravarthi Saravanan. An insight into the critical role of gut microbiota in triggering the phthalate-induced toxicity and its mitigation using probiotics. The Science of the total environment. 2023 Sep; 904(?):166889. doi: 10.1016/j.scitotenv.2023.166889. [PMID: 37683852]
  • Sabir Khan, Shafia Arshad, Imran Masood, Amina Arif, Saba Abbas, Asma Waheed Qureshi, Asia Parveen, Zeemal Seemab Ameen. GC-MS Analysis of Persicaria bistorta: Uncovering the Molecular Basis of Its Traditional Medicinal Use. Applied biochemistry and biotechnology. 2023 Jul; ?(?):. doi: 10.1007/s12010-023-04580-0. [PMID: 37515679]
  • Ayoub Kdimy, Seong Jong Kim, Zulfiqar Ali, Md Imdadul H Khan, Siddharth K Tripathi, Souad El Hajjaji, Hoang V Le. Isolation of Two Plasticizers, Bis(2-Ethylhexyl) Terephthalate and Bis(2-Ethylhexyl) Phthalate, from Capparis spinosa L. Leaves. Chemistry & biodiversity. 2023 Jul; ?(?):e202300903. doi: 10.1002/cbdv.202300903. [PMID: 37505806]
  • Fitra Fauziah, Hirowati Ali, Cimi Ilmiawati, Eko Fuji Ariyanto, Dwi Dinni Aulia Bakhtra, Deslina Setria Mita, Nova Syafni, Dian Handayani. Non-monotonic dose-response of di-(2-ethylhexyl) phthalate isolated from Penicillium citrinum XT6 on adipogenesis and expression of PPARγ and GLUT4 in 3T3-L1 adipocytes. Journal of complementary & integrative medicine. 2023 Jul; ?(?):. doi: 10.1515/jcim-2023-0137. [PMID: 37474486]
  • Sammani Ramanayaka, Meththika Vithanage, Hao Zhang, Kirk T Semple. Role of soil organic matter on the retention and mobility of common plastic additives, Di(2-ethylhexyl) phthalate, bisphenol A and benzophenone, in soil. Environmental research. 2023 Jul; 236(Pt 1):116725. doi: 10.1016/j.envres.2023.116725. [PMID: 37487922]
  • Chenghong Long, Zhenru Li, Shijin Liang, Sitong Yao, Songqi Zhu, Lin Lu, Rui Cao, Yingni Chen, Yuxin Huang, Yongjiang Ma, Wei Lei, Xiaohuan Liang. Resveratrol reliefs DEHP-induced defects during human decidualization. Ecotoxicology and environmental safety. 2023 Jun; 258(?):114931. doi: 10.1016/j.ecoenv.2023.114931. [PMID: 37121080]
  • Haoyan Xiao, Yanji Liu, Hanxia Yu, Niraj Yadav, Jing He, Lige Zhang, Wenbing Tan. Combined toxicity influence of polypropylene microplastics and di-2-ethylhexyl phthalate on physiological-biochemical characteristics of cucumber (Cucumis sativus L.). Plant physiology and biochemistry : PPB. 2023 Jun; 201(?):107811. doi: 10.1016/j.plaphy.2023.107811. [PMID: 37307719]
  • Wenjie Ren, Rui Zhao, Ying Teng, Yongming Luo. Collection of Alfalfa Root Exudates to Study the Impact of Di(2-ethylhexyl) Phthalate on Metabolite Production. Journal of visualized experiments : JoVE. 2023 06; ?(196):. doi: 10.3791/64470. [PMID: 37335114]
  • Huanhuan Xing, Xiaolong Yu, Jianteng Sun, Guining Lu, Minghan Zhu, Jiahao Liang, Ling Jin, Lizhong Zhu. Interaction between Phthalate Ester and Rice Plants: Novel Transformation Pathways and Metabolic-Network Perturbations. Environmental science & technology. 2023 Jun; ?(?):. doi: 10.1021/acs.est.2c09737. [PMID: 37260373]
  • Hang Liu, Hongyang Cui, Yixuan Huang, Yi Yang, Ling Jiao, Yulan Zhou, Jianying Hu, Yi Wan. Enzyme-Catalyzed Hydrogen-Deuterium Exchange between Environmental Pollutants and Enzyme-Regulated Endogenous Metabolites. Environmental science & technology. 2023 05; 57(17):6844-6853. doi: 10.1021/acs.est.2c08056. [PMID: 37080910]
  • Qi Xu, Shuang Ding, Wen Qi, Xueting Zhang, Meng Zhang, Jiqiang Xing, Aipeng Ju, Liting Zhou, Lin Ye. JAK3/STAT5b/PPARγ Pathway Mediates the Association between Di(2-ethylhexyl) Phthalate Exposure and Lipid Metabolic Disorder in Chinese Adolescent Students. Chemical research in toxicology. 2023 Apr; ?(?):. doi: 10.1021/acs.chemrestox.2c00365. [PMID: 37093692]
  • Juan Wu, Yugang Lai, Haofeng Zhu, Xindong Yang, Xintao Ye, Anping Zhang, Jianqiang Sun. Phthalate esters and their metabolites in paired soil-crop systems from farmland in major provinces of eastern China: Pollution characteristics and implications for human exposure. The Science of the total environment. 2023 Apr; 882(?):163645. doi: 10.1016/j.scitotenv.2023.163645. [PMID: 37088394]
  • L Earl Gray. Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats. Toxicology and applied pharmacology. 2023 04; 465(?):116454. doi: 10.1016/j.taap.2023.116454. [PMID: 36921846]
  • Jones B Graceli, Charles S da Costa, Mary J Laws, Ashley R K Deviney, Daryl Meling, Jodi A Flaws. Chronic exposure to a mixture of phthalates shifts the white and brown adipose tissue phenotype in female mice. Toxicological sciences : an official journal of the Society of Toxicology. 2023 Apr; ?(?):. doi: 10.1093/toxsci/kfad032. [PMID: 37021957]
  • Huiyan Yang, Mingsheng Li, Cui Zhang, Na Li, Xiangfeng Yao, Xianxu Li, Fang Li, Jun Wang. Ecotoxicological and biochemical effects of di(2-ethylhexyl)phthalate on wheat (Jimai 22, Triticum aestivum L.). Journal of hazardous materials. 2023 04; 447(?):130816. doi: 10.1016/j.jhazmat.2023.130816. [PMID: 36680896]
  • Xiaolong Yu, Huanhuan Xing, Jianteng Sun, Xiaodong Du, Guining Lu, Lizhong Zhu. New insight into phytometabolism and phytotoxicity mechanism of widespread plasticizer di (2-ethylhexyl) phthalate in rice plants. The Science of the total environment. 2023 Apr; 880(?):163254. doi: 10.1016/j.scitotenv.2023.163254. [PMID: 37019237]
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