Dibromochloromethane (BioDeep_00000010088)

 

Secondary id: BioDeep_00001873654

human metabolite


代谢物信息卡片


Dibromo-chloro-methane

化学式: CHBr2Cl (205.8133)
中文名称: 二溴一氯甲烷标准溶液, 氯二溴甲烷
谱图信息: 最多检出来源 Homo sapiens(not specific) 42%

分子结构信息

SMILES: C(Cl)(Br)Br
InChI: InChI=1S/CHBr2Cl/c2-1(3)4/h1H

描述信息

Dibromochloromethane belongs to the family of Organochlorides. These are organic compounds containing a chlorine atom

同义名列表

6 个代谢物同义名

Dibromo-chloro-methane; Dibromo(chloro)methane; DIBROMOCHLOROMETHANE; CHLORODIBROMOMETHANE; Chlorodibromomethane; Chlorodibromomethane



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ALB, AXIN2, CYP2D6, CYP2E1, ELANE, GSTT1, GSTZ1, HPGDS, KYAT1
Peripheral membrane protein 1 CYP2E1
Endoplasmic reticulum membrane 2 CYP2D6, CYP2E1
Nucleus 2 ALB, AXIN2
cytosol 8 ALB, AXIN2, ELANE, GPT, GSTT1, GSTZ1, HPGDS, KYAT1
phagocytic vesicle 1 ELANE
centrosome 2 ALB, AXIN2
nucleoplasm 1 HPGDS
Cell membrane 1 IL6R
cell surface 3 BMP2, ELANE, TPO
Golgi apparatus 1 ALB
mitochondrial inner membrane 3 ATP5ME, CYP2E1, SQOR
Cytoplasm, cytosol 1 KYAT1
plasma membrane 6 AXIN2, BCHE, BMP2, IL6R, MUC5AC, TPO
Membrane 3 CYP2D6, IL6R, TPO
apical plasma membrane 1 IL6R
axon 1 CCK
extracellular exosome 6 ALB, BMP3, ELANE, GPT, GSTT1, MUC5AC
endoplasmic reticulum 2 ALB, CYP2D6
extracellular space 10 ALB, BCHE, BMP2, BMP3, CCK, ELANE, IL6R, MUC5AC, TG, TPO
mitochondrion 5 ATP5ME, CYP2D6, GSTZ1, KYAT1, SQOR
protein-containing complex 1 ALB
intracellular membrane-bounded organelle 4 BMP2, CYP2D6, CYP2E1, HPGDS
Microsome membrane 2 CYP2D6, CYP2E1
Single-pass type I membrane protein 2 IL6R, TPO
Secreted 7 ALB, BCHE, BMP2, BMP3, CCK, MUC5AC, TG
extracellular region 9 ALB, BCHE, BMP2, BMP3, CCK, ELANE, IL6R, MUC5AC, TG
Single-pass membrane protein 1 CYP2D6
[Isoform 2]: Secreted 1 IL6R
mitochondrial matrix 1 GSTZ1
anchoring junction 1 ALB
external side of plasma membrane 1 IL6R
beta-catenin destruction complex 1 AXIN2
Mitochondrion inner membrane 1 CYP2E1
extracellular matrix 1 MUC5AC
collagen-containing extracellular matrix 1 ELANE
secretory granule 1 ELANE
receptor complex 1 IL6R
ciliary basal body 1 ALB
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 2 ALB, BCHE
Golgi lumen 1 MUC5AC
endoplasmic reticulum lumen 2 ALB, BCHE
transcription repressor complex 1 ELANE
platelet alpha granule lumen 1 ALB
specific granule lumen 1 ELANE
azurophil granule lumen 1 ELANE
nuclear envelope lumen 1 BCHE
[Isoform 1]: Cell membrane 1 IL6R
Cytoplasmic vesicle, phagosome 1 ELANE
mucus layer 1 MUC5AC
proton-transporting ATP synthase complex 1 ATP5ME
proton-transporting ATP synthase complex, coupling factor F(o) 1 ATP5ME
interleukin-6 receptor complex 1 IL6R
[Soluble interleukin-6 receptor subunit alpha]: Secreted 1 IL6R
ciliary neurotrophic factor receptor complex 1 IL6R
BMP receptor complex 1 BMP2
ciliary transition fiber 1 ALB


文献列表

  • Hui Li, Yangyang Chu, Yanping Zhu, Xiaomeng Han, Shihu Shu. Trihalomethane prediction model for water supply system based on machine learning and Log-linear regression. Environmental geochemistry and health. 2024 Jan; 46(2):31. doi: 10.1007/s10653-023-01778-3. [PMID: 38227052]
  • Naseeba Parveen, Papiya Mondal, Kumar Raja Vanapalli, Abhijit Das, Sudha Goel. Phytotoxicity of trihalomethanes and trichloroacetic acid on Vigna radiata and Allium cepa plant models. Environmental science and pollution research international. 2024 Jan; 31(4):5100-5115. doi: 10.1007/s11356-023-31419-2. [PMID: 38110686]
  • Yang Sun, Yi-Xin Wang, Vicente Mustieles, Zhilei Shan, Yu Zhang, Carmen Messerlian. Blood trihalomethane concentrations and allergic sensitization: A nationwide cross-sectional study. The Science of the total environment. 2023 Feb; ?(?):162100. doi: 10.1016/j.scitotenv.2023.162100. [PMID: 36764558]
  • Yang Sun, Yi-Xin Wang, Chong Liu, Ying-Jun Chen, Wen-Qing Lu, Carmen Messerlian. Trimester-Specific Blood Trihalomethane and Urinary Haloacetic Acid Concentrations and Adverse Birth Outcomes: Identifying Windows of Vulnerability during Pregnancy. Environmental health perspectives. 2020 10; 128(10):107001. doi: 10.1289/ehp7195. [PMID: 33026246]
  • Bin Zhou, Pan Yang, Ya-Jie Gong, Qiang Zeng, Wen-Qing Lu, Xiao-Ping Miao. Effect modification of CPY2E1 and GSTZ1 genetic polymorphisms on associations between prenatal disinfection by-products exposure and birth outcomes. Environmental pollution (Barking, Essex : 1987). 2018 Dec; 243(Pt B):1126-1133. doi: 10.1016/j.envpol.2018.09.083. [PMID: 30253304]
  • Ying Zhang, Ning Zhang, Zhiguang Niu. Health risk assessment of trihalomethanes mixtures from daily water-related activities via multi-pathway exposure based on PBPK model. Ecotoxicology and environmental safety. 2018 Nov; 163(?):427-435. doi: 10.1016/j.ecoenv.2018.07.073. [PMID: 30075445]
  • Cong Li, Feng Luo, Feilong Dong, Jingguo Zhao, Tuqiao Zhang, Guilin He, Leslie Cizmas, Virender K Sharma. Chlorine decay and trihalomethane formation following ferrate(VI) preoxidation and chlorination of drinking water. Chemosphere. 2017 Nov; 187(?):413-420. doi: 10.1016/j.chemosphere.2017.08.084. [PMID: 28863294]
  • Jelle Vlaanderen, Karin van Veldhoven, Laia Font-Ribera, Cristina M Villanueva, Marc Chadeau-Hyam, Lützen Portengen, Joan O Grimalt, Christian Zwiener, Dick Heederik, Xiangru Zhang, Paolo Vineis, Manolis Kogevinas, Roel Vermeulen. Acute changes in serum immune markers due to swimming in a chlorinated pool. Environment international. 2017 08; 105(?):1-11. doi: 10.1016/j.envint.2017.04.009. [PMID: 28478232]
  • Minashree Kumari, S K Gupta, B K Mishra. Multi-exposure cancer and non-cancer risk assessment of trihalomethanes in drinking water supplies - A case study of Eastern region of India. Ecotoxicology and environmental safety. 2015 Mar; 113(?):433-8. doi: 10.1016/j.ecoenv.2014.12.028. [PMID: 25544653]
  • Qiang Zeng, Min Li, Shao-Hua Xie, Long-Jie Gu, Jing Yue, Wen-Cheng Cao, Dan Zheng, Ai-Lin Liu, Yu-Feng Li, Wen-Qing Lu. Baseline blood trihalomethanes, semen parameters and serum total testosterone: a cross-sectional study in China. Environment international. 2013 Apr; 54(?):134-40. doi: 10.1016/j.envint.2013.01.016. [PMID: 23454109]
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  • Xin Chen, Dong Zhang, Yin-hao Lu, Wei-wei Zheng, Yu-xin Wu, Xiao Wei, Da-jun Tian, Xia Wang, Hao Zhang, Shuai Guo, Song-hui Jiang, Wei-dong Qu. [Formation and changes of regulated trihalomethanes and haloacetic acids in raw water of Yangtze River, Huangpu River and different treatment processes and pipelines network]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. 2010 Oct; 44(10):893-8. doi: ". [PMID: 21176519]
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