Exact Mass: 334.02899859999997
Exact Mass Matches: 334.02899859999997
Found 343 metabolites which its exact mass value is equals to given mass value 334.02899859999997,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Nicotinamide ribotide
Acquisition and generation of the data is financially supported in part by CREST/JST. COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS β-nicotinamide mononucleotide (β-NM) is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD+ intermediate. The pharmacological activities of β-nicotinamide mononucleotide include its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity[1].
Glycerophosphoinositol
Glycerophosphoinositol (CAS: 16824-65-0), also known as 1-(sn-glycero-3-phospho)-1D-myo-inositol, is produced through deacylation by phospholipase B of the essential phospholipid phosphatidylinositol. Glycerophosphoinositols are ubiquitous phosphoinositide metabolites involved in the control of several cell functions. They exert their actions both intracellularly and by rapidly equilibrating across the plasma membrane. Their transport is mediated by the Glut2 transporter, the human ortholog of GIT1 (PMID: 17141226). Glycerophosphoinositol is a substrate for glycerophosphoinositol inositolphosphodiesterase (EC 3.1.4.43) and is involved in the following reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O = glycerol + 1D-myo-inositol 1-phosphate. It is also a substrate for glycerophosphoinositol glycerophosphodiesterase (EC 3.1.4.44) which catalyzes the chemical reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate. Isolated from beef liver. Glycerylphosphoinositol is found in animal foods.
2-(alpha-D-Galactosyl)-sn-glycerol 3-phosphate
1-alpha-D-galactosyl-sn-glycerol 3-phosphate
Lormetazepam
Lormetazepam, also known as methyllorazepam or (+-)-lorazepam, is a member of the class of compounds known as 1,4-benzodiazepines. 1,4-benzodiazepines are organic compounds containing a benzene ring fused to a 1,4-azepine. Lormetazepam is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Lormetazepam can be found in potato, which makes lormetazepam a potential biomarker for the consumption of this food product. Lormetazepam is a non-carcinogenic (not listed by IARC) potentially toxic compound. Lormetazepam is a drug which is used for the treatment of short-term insomnia [l927. The Dutch, British, and French system called the System of Objectified Judgement Analysis for assessing whether drugs should be included in drug formularies based on clinical efficacy, adverse effects, pharmacokinetic properties, toxicity, and drug interactions was used to assess lormetazepam. A Dutch analysis using the system found that lormetazepam could be suitable to be included in drug prescribing formularies, although zolpidem, zopiclone, and temazepam had higher scores and thus can be seen as relatively favorable . The primary manifestation of overdosage ranges from drowsiness to coma and symptoms may include ataxia, hypotension, hypotonia, respiratory depression which may lead to death [L927]. Lormetazepam (INN, or methyl-lorazepam, is a drug which is a short to intermediate acting 3-hydroxy benzodiazepine derivative. It possesses hypnotic, anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Lormetazepam is considered a hypnotic benzodiazepine and is officially indicated for moderate to severe insomnia. Lormetazepam is a short-acting benzodiazepine and is sometimes used in patients who have difficulty in maintaining sleep or falling asleep. Hypnotics should only be used on a short-term basis or, in those with chronic insomnia, on an occasional basis. D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives N - Nervous system > N05 - Psycholeptics > N05C - Hypnotics and sedatives > N05CD - Benzodiazepine derivatives C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C1012 - Benzodiazepine C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent
3,3',4',5,6,7,8-Heptahydroxyflavone
3,3,4,5,6,7,8-Heptahydroxyflavone is isolated from petals of African marigold (Tagetes erecta
Hovenitin I
Hovenitin II is a constituent of the seeds and fruit of Hovenia dulcis (raisin tree). Constituent of the seeds and fruit of Hovenia dulcis (raisin tree).
Xanthotoxol arabinoside
Xanthotoxol arabinoside is found in herbs and spices. Xanthotoxol arabinoside is a constituent of Ruta graveolens (rue)
2-Methyl-1,4-naphthalenediol bis(dihydrogen phosphate)
Prothrombogenic vitamin. Prothrombogenic vitamin
Menadiol disulfate
Menadiol disulfate is a synthetic vitamin K analogue; prothrombogenic agent. Synthetic vitamin K analogue; prothrombogenic agent
5-(3',4',5'-Trihydroxyphenyl)-gamma-valerolactone-O-methyl-O-sulphate
C12H14O9S (334.03585140000007)
5-(3,4,5-Trihydroxyphenyl)-gamma-valerolactone-O-methyl-O-sulphate belongs to the family of Methoxyphenols and Derivatives. These are compounds containing a methoxy group attached to the benzene ring of a phenol moiety.
(4-Sulfamoylphenyl) 4-(diaminomethylideneamino)benzoate
C14H14N4O4S (334.07357240000005)
6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide
C12H6N4O6S (334.00080560000004)
(5R,6S)-3-(2-Carbamoyloxyethylsulfanyl)-6-(1-hydroxyethyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
1-(2,4-Dichlorobenzyl)-1H-indazole-3-carbohydrazide
Adjudin is an extensively studied male contraceptive with a superior mitochondria-inhibitory effect. Adjudin is also a potent Cl- channel blocker.
2-[(4-Benzamidophenyl)sulfonylamino]acetic acid
C15H14N2O5S (334.06233940000004)
Chlorethylclonidine
C13H17Cl3N4 (334.05187320000005)
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D009676 - Noxae > D000477 - Alkylating Agents
Chlorsulfaquinoxaline
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor > C1748 - Topoisomerase Inhibitor D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
Salacinol
(2s)-7-Tert-Butyl-6-Chloro-2-(Trifluoromethyl)-2h-Chromene-3-Carboxylic Acid
NMNH
Nmnh is a member of the class of compounds known as nicotinamide nucleotides. Nicotinamide nucleotides are pyridine nucleotides, in which the pyridine base is nicotinamide or a derivative thereof. Nmnh is soluble (in water) and a moderately acidic compound (based on its pKa). Nmnh can be found in a number of food items such as yautia, common grape, rocket salad (sspecies), and oval-leaf huckleberry, which makes nmnh a potential biomarker for the consumption of these food products.
Cedrin
Cedrin is a natural product found in Cedrus deodara with data available.
Amaronol B
(-)-2-((3,5-Dihydroxy-4-methoxyphenyl)methyl)-2,4,6-trihydroxy-3(2H)-benzofuranone is a member of aurones. Amaronol B is a natural product found in Pseudolarix amabilis and Larix kaempferi with data available.
Dehydrodolineone
3-[5-(2-Pyridyl)-2-thienyl]prop-2-ynyl N-phenylcarbamate
3-Nitro-2,6-bis(3-pyridyloxy)benzonitrile
C17H10N4O4 (334.07020200000005)
1,3,6-Trihydroxy-2,5,7-trimethoxy-9H-xanthene-9-one
cephalosol|methyl 8-hydroxy-10-methoxy-3-methyl-5,7-dioxo-5,7-dihydro-1H-furo[3,4-c]isochromen-3-yl-acetate
3-(2,4-dihydroxy-6-methylbenzoyloxy)-2,4-dihydroxy-6-methylbenzoic acid|papulosic acid
afrostyraxthioside C|methylsulfonylthiomethyl 1-thio-beta-D-glucopyranoside
8-hydroxy-2-[1-hydroxyethyl]-5,7-dimethoxynaphtho[2,3-b] thiophene-4,9-dione
C16H14O6S (334.05110640000004)
Tri-Me ether-4-Chloro-1, 3, 6-trihydroxy-8-methylxanthone
9H-Xanthen-9-one, 1,3,8-trihydroxy-2,4,6-trimethoxy-
2-Chloro-1,3,6-trimethoxy-8-methyl-9H-xanthen-9-one
β-Nicotinamide mononucleotide
β-nicotinamide mononucleotide (β-NM) is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD+ intermediate. The pharmacological activities of β-nicotinamide mononucleotide include its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity[1].
(2S,3S)-3,5,7-trihydroxy-6-methyl-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one
6-chloro-4,5,7-trihydroxy-9,10-dioxoanthracene-2-carboxylic acid
(2S,3S)-3,5,7-trihydroxy-6-methyl-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one
Nicotinamide mononucleotide
COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS β-nicotinamide mononucleotide (β-NM) is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD+ intermediate. The pharmacological activities of β-nicotinamide mononucleotide include its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity[1].
Lormetazepam
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives N - Nervous system > N05 - Psycholeptics > N05C - Hypnotics and sedatives > N05CD - Benzodiazepine derivatives C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C1012 - Benzodiazepine C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent
(2S,3S)-3,5,7-trihydroxy-6-methyl-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one [IIN-based: Match]
Loramet
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives N - Nervous system > N05 - Psycholeptics > N05C - Hypnotics and sedatives > N05CD - Benzodiazepine derivatives C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C1012 - Benzodiazepine C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent
6-chloro-4,5,7-trihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid
4-([2,2-bithiophen]-5-yl)but-3-yne-1,2-diyl diacetate
Magnesium oratate
A - Alimentary tract and metabolism > A12 - Mineral supplements > A12C - Other mineral supplements > A12CC - Magnesium
5-(3-BUTYLUREIDO)-2-ETHOXYBENZENESULFONYLCHLORIDE
C13H19ClN2O4S (334.07540040000004)
Hexafluoro-2,3-bis-(trifluoromethyl)-2,3-butanediol
C6H2F12O2 (333.98631759999995)
[7-chloro-5-(2-chlorophenyl)-1-methyl-2,3-dihydro-1,4-benzodiazepin-2-yl]methanol
C17H16Cl2N2O (334.06396259999997)
3-[4-[(4-CHLOROBENZYL)OXY]PHENYL]-5-(CHLOROMETHYL)-1,2,4-OXADIAZOLE
5-bromo-1-(2-oxo-2-pyrrolidin-1-ylethyl)indole-3-carbaldehyde
ETHYL 5-AMINO-1-(2-BROMOPHENYL)-4-CYANO-1H-PYRAZOLE-3-CARBOXYLATE
C13H11BrN4O2 (334.00653259999996)
ETHYL 5-AMINO-1-(3-BROMOPHENYL)-4-CYANO-1H-PYRAZOLE-3-CARBOXYLATE
C13H11BrN4O2 (334.00653259999996)
N-(4-chlorophenyl)-1-(pyrimidin-2-yl)-1H-pyrrole-2-sulfonamide
(2,4,6-TRIMETHYL-PHENOXY)-ACETICACID
C15H20Cl2O4 (334.07385800000003)
1H-PYRROLO[2,3-B]PYRIDINE, 4-CHLORO-2-(3,4,5-TRIMETHOXYPHENYL)-, 7-OXIDE
C16H15ClN2O4 (334.07203000000004)
3,5-BIS(TRIFLUOROMETHYL)-[1,1-BIPHENYL]-4-CARBOXYLIC ACID
C15H8F6O2 (334.04284599999994)
(Z)-2-(2,4-DICHLORO-5-FLUORO-BENZOYL)-3-ETHOXY-ACRYLIC ACID ETHYL ESTER
Methyl 3-(trifluoromethylsulfonyloxy)-2-naphthoate
C13H9F3O5S (334.01227800000004)
(4-TERT-BUTYLPHENYL)DIPHENYLSULFONIUMTRIFLATE
C15H8F6O2 (334.04284599999994)
8-CHLORO-2-(4-ISOPROPYLTHIAZOL-2-YL)-7-METHOXYQUINOLIN-4-OL
N-(3-IODO-4-METHOXY-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE
C11H15IN2O2 (334.01782399999996)
3-(N-ACETYL-L-CYSTEIN-S-YL)ACETAMINOPHEN SODIUM SALT
tert-Butyl (5-Bromo-2-(methylthio)-6-oxopyrimidin-1-yl)acetate
C11H15BrN2O3S (333.99867000000006)
3-(4-chlorophenyl)-4,5-dihydro-1-[4-(methylsulphonyl)phenyl]-1H-pyrazole
4,4-((1R,2R)-1,2-DIAMINOETHANE-1,2-DIYL)DIBENZONITRILE DIHYDROCHLORIDE
4-(bromomethyl)-1-methyl-5-phenoxy-3-(trifluoromethyl)pyrazole
ETHANONE, 1-[4-CHLORO-1-(PHENYLSULFONYL)-1H-PYRROLO[2,3-B]PYRIDIN-3-YL]-
3-Methylbutyl 2-hydroxy-5-iodobenzoate
C12H15IO3 (334.00659099999996)
methyl 3-iodo-4-[(2-methylpropan-2-yl)oxy]benzoate
C12H15IO3 (334.00659099999996)
ethyl 3-iodo-4-propan-2-yloxybenzoate
C12H15IO3 (334.00659099999996)
3-[(2-chloro-6-fluorophenyl)methyl]-7,7-dimethyl-6,8-dihydrochromene-2,5-dione
C18H16ClFO3 (334.07719480000003)
methyl 4-(4-methoxycarbonylphenyl)sulfonylbenzoate
C16H14O6S (334.05110640000004)
4-(3-(4-(TRIFLUOROMETHYL)PHENYL)-1,2,4-OXADIAZOL-5-YL)BENZOIC ACID
C16H9F3N2O3 (334.05652399999997)
4-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)THIOPHEN-2-CARBOXYLIC ACID ETHYLESTER
ethyl 7-chloro-8-cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate
4-Imidazolidinone, 2-(2,6-dichlorophenyl)-1-[(1R)-1-phenylethyl]-, (2R)-
C17H16Cl2N2O (334.06396259999997)
3,5-BIS(TRIFLUOROMETHYL)-[1,1-BIPHENYL]-3-CARBOXYLIC ACID
C15H8F6O2 (334.04284599999994)
1-[5-bromo-3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]indol-1-yl]ethanone
C16H19BrN2O (334.06806639999996)
3-(2-(2-Bromoacetamido)acetamido)-proxyl free radical
C12H21BrN3O3 (334.0766196000001)
Ethyl 5-amino-1-(4-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylate
C13H11BrN4O2 (334.00653259999996)
Propanamide, N-(4-iodo-2-methoxy-3-pyridinyl)-2,2-dimethyl-
C11H15IN2O2 (334.01782399999996)
METHYL 2-TRIFLUOROMETHANESULFONYLOXY-1-NAPHTHOATE
C13H9F3O5S (334.01227800000004)
DICHLORO(2,6,10-DODECATRIENE-1,12-DIYL)RUTHENIUM(IV)
3-Iodo-4-(3-methylbutoxy)benzoic acid
C12H15IO3 (334.00659099999996)
3-iodo-4-pentan-2-yloxybenzoic acid
C12H15IO3 (334.00659099999996)
4-(2,2-Dimethylpropoxy)-3-iodobenzoic acid
C12H15IO3 (334.00659099999996)
N,N-dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamide
1-(4-Bromophenyl)-3-(2-phenylethyl)thiourea
C15H15BrN2S (334.01392500000003)
1-Phenyl-2-[[4-(trifluoromethyl)phenyl]methylthio]imidazole
C17H13F3N2S (334.07514940000004)
3-(1-hydroxy-1H-1,2,3-benzotriazole-6-sulfonamido)benzoic acid
4-(4-morpholinyl)-3-nitro-N-(2-thiazolyl)benzamide
C14H14N4O4S (334.07357240000005)
5-[[(5,6-Dimethyl-4-thieno[2,3-d]pyrimidinyl)thio]methyl]-2-furancarboxylic acid methyl ester
1-benzyl-2-(methylsulfanyl)-4,5-dihydro-1H-imidazole hydroiodide
6-Chloro-4,5,7-trihydroxy-9,10-dihydro-9,10-dioxoanthracene-2-carboxylic acid
(9as)-4-Bromo-9a-Butyl-7-Hydroxy-1,2,9,9a-Tetrahydro-3h-Fluoren-3-One
C17H19BrO2 (334.05683339999996)
5-(6-chloro-2,3-dihydro-1,4-benzoxazin-4-yl)-N-cyclopropylthiophene-2-carboxamide
5-(4-chloro-2-hydroxy-phenoxy)-N-(5-methylisoxazol-3-yl)furan-2-carboxamide
[5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
S-formylglutathionate(1-)
The conjugate base of S-formylglutathione having anionic carboxy groups and a protonated primary amino group. COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
5-Hydroxy-6,8-dimethoxy-1,4-dioxo-3-(2-oxopropyl)naphthalene-2-carboxylic acid
(2R,3R,4S,5R,6S)-2,3,4,5,6-pentahydroxy-7-oxo-8-phosphonooxyoctanoic acid
C8H15O12P (334.03011200000003)
2-hydroxy-2-[(2R,3S,4R,5S,6R)-3,4,5,6-tetrahydroxy-6-(phosphonooxymethyl)oxan-2-yl]acetic acid
C8H15O12P (334.03011200000003)
4-Chloro-6-[5-(4-Methoxyphenyl)-1,2,3-Thiadiazol-4-Yl]benzene-1,3-Diol
5-[(2-chlorophenoxy)methyl]-N-(2-thiazolyl)-2-furancarboxamide
3-Imidazo[1,2-a]pyridinyl-diphenyl-sulfanylidenephosphorane
C19H15N2PS (334.06935200000004)
2-(4-chlorophenyl)-N-[(2-hydroxy-5-methylanilino)-sulfanylidenemethyl]acetamide
4-[5-[3-(Trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]benzoic acid
C16H9F3N2O3 (334.05652399999997)
(2s,3s)-3,5,7-Trihydroxy-6-methyl-2-(3,4,5-trihydroxyphenyl)chroman-4-one
2-(2-bromo-4-methylphenoxy)-N-(pyridin-2-ylmethyl)acetamide
N-[(2-fluorophenyl)carbamothioyl]-2-(4-methoxyphenoxy)acetamide
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3-chloro-2-methylphenyl)thiourea
5-Nitro-2-thiophenecarboxylic acid [2-oxo-2-(1-phenylethylamino)ethyl] ester
C15H14N2O5S (334.06233940000004)
2-[2-(4-Fluoroanilino)-4-thiophen-2-yl-5-thiazolyl]acetic acid
4-Amino-2-[(2,5-dichlorophenyl)-oxomethyl]isoindole-1,3-dione
2-Amino-5-[1-(carboxylatomethylcarbamoyl)-2-nitrososulfanyl-ethyl]amino-5-oxo-pentanoate
3-(4-Methoxyphenyl)-6-phenyl-4-thieno[2,3-d]pyrimidinone
4-[5-[2-(Trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]benzoic acid
C16H9F3N2O3 (334.05652399999997)
3-[3-(2-bromophenyl)acryloyl]-4-hydroxy-6-methyl-2H-pyran-2-one
4-Methyl-5-thieno[3,2-b]pyrrolecarboxylic acid [2-oxo-2-(thiophen-2-ylmethylamino)ethyl] ester
N-(3-sulamoylphenyl)-2,3-dihydro-1,4-benzodioxine-3-carboxamide
C15H14N2O5S (334.06233940000004)
6-bromo-2-[(3-methoxyphenoxy)methyl]-1H-imidazo[4,5-b]pyridin-4-ium
C14H13BrN3O2+ (334.01910780000003)
[3-(7-Hydroxy-4-oxochromen-2-yl)phenyl] hydrogen sulate
[3-(3-Hydroxy-4-oxochromen-2-yl)phenyl] hydrogen sulate
7-Hydroxy-6-methoxy-3-(1,2,5-trihydroxy-4-oxocyclohex-2-en-1-yl)chromen-4-one
3,5,7-Trihydroxy-2-(1-hydroxy-3-methoxy-4-oxocyclohex-2-en-1-yl)chromen-4-one
[1-(6,7-Dimethoxy-1,3-benzodioxol-5-yl)-3-oxopropyl] hydrogen sulate
C12H14O9S (334.03585140000007)
(2S)-2-(1,3-benzoxazol-2-ylsulfanyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)butanamide
6-Methoxytaxifolin
A pentahydroxyflavanone that is (+)-taxifolin substituted by a methoxy group at position 6.
1-(sn-Glycero-3-phospho)-1D-myo-inositol
A myo-inositol monophosphate derivative that is 1D-myo-inositol substituted at position 1 by an sn-glycero-3-phospho group.
5-(3,4,5-Trihydroxyphenyl)-gamma-valerolactone-O-methyl-O-sulphate
C12H14O9S (334.03585140000007)
NMNH(2-)
An organophosphate oxoanion arising from deprotonation of the phosphate OH groups of NMNH; major species at pH 7.3.
GSK-1482160
C14H14ClF3N2O2 (334.06958499999996)
GSK-1482160 is an orally available negative allosteric modulator of the P2X7 receptor. P2X7 receptors are involved in the production of pro-inflammatory cytokines, such as Il-1β, by central and peripheral immune cells. GSK-1482160 has the potential for the research of inflammation diseases[1].
H4R antagonist 1
C11H11BrN8 (334.02899859999997)
H4R antagonist 1 is a potent and highly selective histamine H4 receptor (H4R) antagonist with an IC50 of 27 nM. H4R antagonist 1 does not show any noticeable binding affinity to other subtypes of histamine receptors, H1R, H2R, and H3R[1].
2-(3,5-dihydroxy-4-methoxyphenyl)-3,5,7-trihydroxy-2,3-dihydro-1-benzopyran-4-one
methyl 4-chloro-3,8-dihydroxy-6-methyl-9-oxoxanthene-1-carboxylate
methyl (5r,5as)-5,10,11-trihydroxy-8-methyl-1-oxo-5h-oxepino[4,3-b]chromene-5a-carboxylate
13-bromo-4-methyl-4,10-diazatetracyclo[8.6.1.0⁵,¹⁷.0¹¹,¹⁶]heptadeca-1(17),11,13,15-tetraen-9-ol
C16H19BrN2O (334.06806639999996)
10-bromo-2-chloro-3,7,11,11-tetramethylspiro[5.5]undec-7-en-3-ol
2-chloro-1,3-dihydroxy-6-(hydroxymethyl)-8-methoxyanthracene-9,10-dione
3,5-dihydroxy-2-(2-methoxy-2-oxoethyl)phenyl 3,4-dihydroxybenzoate
(1r,2r,3'r,4s,4'r)-3'-bromo-4'-chloro-1,3,3,4'-tetramethyl-7-oxaspiro[bicyclo[2.2.1]heptane-2,1'-cyclohexane]
n-[(4s)-4-(5-bromo-1h-indol-3-yl)-3,4,5,6-tetrahydropyrimidin-2-yl]ethanimidic acid
(1r,2r,3r,3'r,4s,4'r)-3'-bromo-4'-chloro-1,3,4,4'-tetramethyl-7-oxaspiro[bicyclo[2.2.1]heptane-2,1'-cyclohexane]
methyl 5,10,11-trihydroxy-4-methyl-1-oxo-5h-oxepino[4,3-b]chromene-5a-carboxylate
methyl 4-chloro-2,8-dihydroxy-6-methyl-9-oxoxanthene-1-carboxylate
(2r)-1-(acetyloxy)-4-{[2,2'-bithiophen]-5-yl}but-3-yn-2-yl acetate
1-chloro-2,4-dihydroxy-7-(hydroxymethyl)-5-methoxyanthracene-9,10-dione
1-[(6s)-1,4,6,9,10-pentahydroxy-7-methoxy-6h-benzo[c]chromen-2-yl]ethanone
(5s)-5-[(6-bromo-1h-indol-3-yl)methyl]-2-imino-1,3-dimethylimidazolidin-4-one
8-bromo-9-chloro-1,4,9-trimethyl-5-methylidenespiro[5.5]undecan-1-ol
6-[(1e,3s,4s)-3-bromo-4-chloro-4-methylcyclohexylidene]-2-methylhept-2-en-4-ol
8-bromo-9-chloro-1,1,9-trimethyl-5-methylidenespiro[5.5]undecan-3-ol
(4s)-6-[(1e,3s,4s)-4-bromo-3-chloro-4-methylcyclohexylidene]-2-methylhept-2-en-4-ol
methyl (1r)-9-hydroxy-1,7-bis(hydroxymethyl)-10-oxopyrano[4,3-b]chromene-1-carboxylate
3,5,6,7-tetrahydroxy-2-(2,3,4-trihydroxyphenyl)chromen-4-one
methyl 7,11,15-trihydroxy-14-methyl-9-oxo-2,12-dioxatricyclo[8.5.0.0³,⁸]pentadeca-3,5,7,10,13-pentaene-1-carboxylate
6-[(1e,3s,4s)-4-bromo-3-chloro-4-methylcyclohexylidene]-2-methylhept-2-en-4-ol
3-[(2r)-3,3-dichloro-2-hydroxypropyl]-5,8-dihydroxy-6-methoxyisochromen-1-one
(2s)-2-[(3,5-dihydroxy-4-methoxyphenyl)methyl]-2,4,6-trihydroxy-1-benzofuran-3-one
(2s,3s,6s,10r)-10-bromo-2-chloro-3,7,11,11-tetramethylspiro[5.5]undec-7-en-3-ol
8-bromo-2-chloro-3,7,7-trimethyl-11-methylidenespiro[5.5]undecan-3-ol
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-6-methoxy-2,3-dihydro-1-benzopyran-4-one
5'-bromo-4'-chloro-1,3,3,4'-tetramethyl-7-oxaspiro[bicyclo[2.2.1]heptane-2,1'-cyclohexane]
methyl 2-{6-hydroxy-8-methoxy-1-methyl-3,5-dioxofuro[3,4-c]isochromen-1-yl}acetate
(2r,3r)-3,5,7-trihydroxy-6-methyl-2-(3,4,5-trihydroxyphenyl)-2,3-dihydro-1-benzopyran-4-one
(2r,3r)-2-(3,5-dihydroxy-4-methoxyphenyl)-3,5,7-trihydroxy-2,3-dihydro-1-benzopyran-4-one
(3s,6r,8s,9s)-8-bromo-9-chloro-1,1,9-trimethyl-5-methylidenespiro[5.5]undecan-3-ol
3-(3,3-dichloro-2-hydroxypropyl)-5,8-dihydroxy-6-methoxyisochromen-1-one
9-bromo-8-chloro-1,1,9-trimethyl-5-methylidenespiro[5.5]undecan-3-ol
3-hydroxy-2-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propoxyphosphonic acid
(2r)-2-[(3,5-dihydroxy-4-methoxyphenyl)methyl]-2,4,6-trihydroxy-1-benzofuran-3-one
6-[(1z)-4-bromo-3-chloro-4-methylcyclohexylidene]-2-methylhept-2-en-4-ol
hexahydroxy-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dione
(3s,4s)-5,10-dihydroxy-4,7-dimethoxy-3-methyl-3h,4h-naphtho[2,3-c]pyran-1,6,9-trione
methyl (5r,5as)-5,10,11-trihydroxy-4-methyl-1-oxo-5h-oxepino[4,3-b]chromene-5a-carboxylate
(2r,3s)-2-(3,5-dihydroxy-4-methoxyphenyl)-3,5,7-trihydroxy-2,3-dihydro-1-benzopyran-4-one
methyl (1s,2s,6s)-6-(2,6-dihydroxy-4-methylbenzoyl)-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-ene-1-carboxylate
3,5,7-trihydroxy-6-methyl-2-(3,4,5-trihydroxyphenyl)-2,3-dihydro-1-benzopyran-4-one
(6s,8r)-8-bromo-2-chloro-3,7,7-trimethyl-11-methylidenespiro[5.5]undecan-3-ol
(9r)-13-bromo-4-methyl-4,10-diazatetracyclo[8.6.1.0⁵,¹⁷.0¹¹,¹⁶]heptadeca-1(17),11,13,15-tetraen-9-ol
C16H19BrN2O (334.06806639999996)
methyl 2-[2,6-dihydroxy-4-(hydroxymethyl)benzoyl]-3,6-dihydroxybenzoate
8-chloro-9,10-dihydroxy-3-methyl-1-propyl-1h-cyclohexa[g]isochromene-6,7-dione
methyl 2-chloro-8-hydroxy-6-(hydroxymethyl)-9-oxoxanthene-1-carboxylate
(4s,7s)-4-benzyl-7-(2-methylpropyl)-1,2,3,5,6-pentathiepane
methyl 5,10,11-trihydroxy-8-methyl-1-oxo-5h-oxepino[4,3-b]chromene-5a-carboxylate
1-{1,4,6,9,10-pentahydroxy-7-methoxy-6h-benzo[c]chromen-2-yl}ethanone
methyl 2-[(1s)-6-hydroxy-8-methoxy-1-methyl-3,5-dioxofuro[3,4-c]isochromen-1-yl]acetate
methyl (4r,5r)-4,5,7-trihydroxy-3-methyl-6-oxo-4h-oxepino[2,3-b]chromene-5-carboxylate
methyl 4,5,7-trihydroxy-9-methyl-6-oxo-4h-oxepino[2,3-b]chromene-5-carboxylate
n-[4-(5-bromo-1h-indol-3-yl)-3,4,5,6-tetrahydropyrimidin-2-yl]ethanimidic acid
3'-bromo-4'-chloro-1,3,4,4'-tetramethyl-7-oxaspiro[bicyclo[2.2.1]heptane-2,1'-cyclohexane]
(5r,9r)-13-bromo-4-methyl-4,10-diazatetracyclo[8.6.1.0⁵,¹⁷.0¹¹,¹⁶]heptadeca-1(17),11,13,15-tetraen-9-ol
C16H19BrN2O (334.06806639999996)
(5s,9s)-13-bromo-4-methyl-4,10-diazatetracyclo[8.6.1.0⁵,¹⁷.0¹¹,¹⁶]heptadeca-1(17),11,13,15-tetraen-9-ol
C16H19BrN2O (334.06806639999996)
(2s,3r)-2-(3,5-dihydroxy-4-methoxyphenyl)-3,5,7-trihydroxy-2,3-dihydro-1-benzopyran-4-one
(5s,9r)-13-bromo-4-methyl-4,10-diazatetracyclo[8.6.1.0⁵,¹⁷.0¹¹,¹⁶]heptadeca-1(17),11,13,15-tetraen-9-ol
C16H19BrN2O (334.06806639999996)