Menadiol diphosphate (BioDeep_00000617869)
代谢物信息卡片
化学式: C11H12O8P2 (334.0007412)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C2=CC=CC=C2C(=C1)OP(=O)(O)O)OP(=O)(O)O
InChI: InChI=1S/C11H12O8P2/c1-7-6-10(18-20(12,13)14)8-4-2-3-5-9(8)11(7)19-21(15,16)17/h2-6H,1H3,(H2,12,13,14)(H2,15,16,17)
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:134713
- PubChem: 8556
- Metlin: METLIN88651
- DrugBank: DB14650
- ChEMBL: CHEMBL1201348
- CAS: 84-98-0
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jennifer Susan Lees, Kenneth Mangion, Elaine Rutherford, Miles D Witham, Rosemary Woodward, Giles Roditi, Tracey Hopkins, Katriona Brooksbank, Alan G Jardine, Patrick B Mark. Vitamin K for kidney transplant organ recipients: investigating vessel stiffness (ViKTORIES): study rationale and protocol of a randomised controlled trial.
Open heart.
2020 07; 7(2):. doi:
10.1136/openhrt-2019-001070. [PMID: 32675297] - Dean Lim, Robert J Morgan, Steven Akman, Kim Margolin, Brian I Carr, Lucille Leong, Oluwole Odujinrin, James H Doroshow. Phase I trial of menadiol diphosphate (vitamin K3) in advanced malignancy.
Investigational new drugs.
2005 Jun; 23(3):235-9. doi:
10.1007/s10637-005-6731-2. [PMID: 15868379] - J Kruk, K Strzalka. Redox changes of cytochrome b(559) in the presence of plastoquinones.
The Journal of biological chemistry.
2001 Jan; 276(1):86-91. doi:
10.1074/jbc.m003602200. [PMID: 11022032] - B Green, S Cairns, R Harvey, M Pettit. Phytomenadione or menadiol in the management of an elevated international normalized ratio (prothrombin time).
Alimentary pharmacology & therapeutics.
2000 Dec; 14(12):1685-9. doi:
10.1046/j.1365-2036.2000.00880.x. [PMID: 11121919] - F A Redegeld, G A Hofman, P G van de Loo, A S Koster, J Noordhoek. Nephrotoxicity of the glutathione conjugate of menadione (2-methyl-1, 4-naphthoquinone) in the isolated perfused rat kidney. Role of metabolism by gamma-glutamyltranspeptidase and probenecid-sensitive transport.
The Journal of pharmacology and experimental therapeutics.
1991 Feb; 256(2):665-9. doi:
. [PMID: 1671599] - J Vanderleyden, E Van Den Eynde, H Verachtert. Nature of the effect of adenosine 5'-monophosphate on the cyanide-insensitive respiration in mitochondria of Moniliella tomentosa.
The Biochemical journal.
1980 Jan; 186(1):309-16. doi:
10.1042/bj1860309. [PMID: 7189398] - H V DYGGVE, E SONDERGAARD, H DAM. Effect of synkavit and vikastab on bilirubin and plasma prothrombin.
Acta paediatrica.
1962 Mar; 51(?):165-8. doi:
10.1111/j.1651-2227.1962.tb06525.x. [PMID: 13888832] - H K HANEL, G HJORT, P R PURSER. Sterol synthesis after whole body roentgen irradiation. III. Effects of synkavit.
Acta radiologica.
1958 Feb; 49(2):141-4. doi:
10.3109/00016925809171498. [PMID: 13520393] - M VEST. [Question of the effect of naphthoquinone derivatives (synkavite) on serum bilirubin content of prematures].
Schweizerische medizinische Wochenschrift.
1958 Jan; 88(3):59-62. doi:
NULL. [PMID: 13528966] - S AURICCHIO, M SCOTTO, M PIAZZA, E QUAGLIARIELLO. [Conversion of 3-hydroxyarthranilic acid to quinolinic acid in presence of kidney and liver extracts of rats treated with synkayvite (2-methyl-1,4-naphthohydroquinone sodium diphosphate)].
Bollettino della Societa italiana di biologia sperimentale.
1957 Aug; 33(8-9):1239-40. doi:
NULL. [PMID: 13522892]