6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide (BioDeep_00000174960)
human metabolite blood metabolite
代谢物信息卡片
化学式: C12H6N4O6S (334.00080560000004)
中文名称:
谱图信息:
最多检出来源 Danio rerio(blood) 3.85%
分子结构信息
SMILES: C1=CC2=C(C(=C1)S(=O)(=O)N)C(=CC3=NC(=O)C(=O)N=C23)[N+](=O)[O-]
InChI: InChI=1S/C12H6N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H2,13,21,22)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Hannah J Seong, Adam G Carter. D1 receptor modulation of action potential firing in a subpopulation of layer 5 pyramidal neurons in the prefrontal cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2012 Aug; 32(31):10516-21. doi:
10.1523/jneurosci.1367-12.2012
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Endocrinology.
2012 May; 153(5):2323-31. doi:
10.1210/en.2011-2079
. [PMID: 22396452] - Ayano Fukuhara, Hidemitsu Nakajima, Yuya Miyamoto, Katsuaki Inoue, Satoshi Kume, Young-Ho Lee, Masanori Noda, Susumu Uchiyama, Shigeru Shimamoto, Shigenori Nishimura, Tadayasu Ohkubo, Yuji Goto, Tadayoshi Takeuchi, Takashi Inui. Drug delivery system for poorly water-soluble compounds using lipocalin-type prostaglandin D synthase.
Journal of controlled release : official journal of the Controlled Release Society.
2012 Apr; 159(1):143-50. doi:
10.1016/j.jconrel.2011.12.020
. [PMID: 22226778] - M P Kurnellas, H Li, M R Jain, S N Giraud, A B Nicot, A Ratnayake, R F Heary, S Elkabes. Reduced expression of plasma membrane calcium ATPase 2 and collapsin response mediator protein 1 promotes death of spinal cord neurons.
Cell death and differentiation.
2010 Sep; 17(9):1501-10. doi:
10.1038/cdd.2010.54
. [PMID: 20489728] - Ping Wan, Yan-Ping Zhang, Jie Yan, Yu-Xia Xu, Hong-Quan Wang, Ru Yang, Cui-Qing Zhu. Glutamate enhances the surface distribution and release of Munc18 in cerebral cortical neurons.
Neuroscience bulletin.
2010 Aug; 26(4):273-81. doi:
10.1007/s12264-010-0411-8
. [PMID: 20651809] - Thomas P Jensen, Lucy E Buckby, Ruth M Empson. Reduced expression of the 'fast' calcium transporter PMCA2a during homeostatic plasticity.
Molecular and cellular neurosciences.
2009 Jul; 41(3):364-72. doi:
10.1016/j.mcn.2009.04.011
. [PMID: 19410650] - S M Goebel-Goody, K D Davies, R M Alvestad Linger, R K Freund, M D Browning. Phospho-regulation of synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult hippocampal slices.
Neuroscience.
2009 Feb; 158(4):1446-59. doi:
10.1016/j.neuroscience.2008.11.006
. [PMID: 19041929] - K Okamoto, D F Bereiter, R Thompson, A Tashiro, D A Bereiter. Estradiol replacement modifies c-fos expression at the spinomedullary junction evoked by temporomandibular joint stimulation in ovariectomized female rats.
Neuroscience.
2008 Oct; 156(3):729-36. doi:
10.1016/j.neuroscience.2008.08.003
. [PMID: 18765271] - Rodrigo C A de Menezes, Dmitry V Zaretsky, Sumit Sarkar, Marco A P Fontes, Joseph A Dimicco. Microinjection of muscimol into the periaqueductal gray suppresses cardiovascular and neuroendocrine response to air jet stress in conscious rats.
American journal of physiology. Regulatory, integrative and comparative physiology.
2008 Sep; 295(3):R881-90. doi:
10.1152/ajpregu.00181.2008
. [PMID: 18650321] - C Busnardo, R F Tavares, J Antunes-Rodrigues, F M A Corrêa. Cardiovascular effects of L-glutamate microinjection in the supraoptic nucleus of unanaesthetized rats.
Neuropharmacology.
2007 May; 52(6):1378-84. doi:
10.1016/j.neuropharm.2007.01.011
. [PMID: 17367824] - Shyam D Rao, Sandra Anne Banack, Paul Alan Cox, John H Weiss. BMAA selectively injures motor neurons via AMPA/kainate receptor activation.
Experimental neurology.
2006 Sep; 201(1):244-52. doi:
10.1016/j.expneurol.2006.04.017
. [PMID: 16764863] - Yukari Yoshida, Keisuke Tsuzuki, Shogo Ishiuchi, Seiji Ozawa. Serum-dependence of AMPA receptor-mediated proliferation in glioma cells.
Pathology international.
2006 May; 56(5):262-71. doi:
10.1111/j.1440-1827.2006.01954.x
. [PMID: 16669875] - Wilhelm Stoffel, Rafael Körner, Dagmar Wachtmann, Bernhard U Keller. Functional analysis of glutamate transporters in excitatory synaptic transmission of GLAST1 and GLAST1/EAAC1 deficient mice.
Brain research. Molecular brain research.
2004 Sep; 128(2):170-81. doi:
10.1016/j.molbrainres.2004.06.026
. [PMID: 15363892] - Hong-Jin Shu, Lawrence N Eisenman, Deepani Jinadasa, Douglas F Covey, Charles F Zorumski, Steven Mennerick. Slow actions of neuroactive steroids at GABAA receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2004 Jul; 24(30):6667-75. doi:
10.1523/jneurosci.1399-04.2004
. [PMID: 15282269] - Sampsa Sipilä, Kristiina Huttu, Juha Voipio, Kai Kaila. GABA uptake via GABA transporter-1 modulates GABAergic transmission in the immature hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2004 Jun; 24(26):5877-80. doi:
10.1523/jneurosci.1287-04.2004
. [PMID: 15229234] - M Martínez-Sánchez, F Striggow, U H Schröder, S Kahlert, K G Reymann, G Reiser. Na(+) and Ca(2+) homeostasis pathways, cell death and protection after oxygen-glucose-deprivation in organotypic hippocampal slice cultures.
Neuroscience.
2004; 128(4):729-40. doi:
10.1016/j.neuroscience.2004.06.074
. [PMID: 15464281] - Qing Hui Chen, Joseph R Haywood, Glenn M Toney. Sympathoexcitation by PVN-injected bicuculline requires activation of excitatory amino acid receptors.
Hypertension (Dallas, Tex. : 1979).
2003 Oct; 42(4):725-31. doi:
10.1161/01.hyp.0000085197.20043.44
. [PMID: 12900439] - Attila D Kovács, Gvido Cebers, Aleta Cebere, Sture Liljequist. Loss of GABAergic neuronal phenotype in primary cerebellar cultures following blockade of glutamate reuptake.
Brain research.
2003 Jul; 977(2):209-20. doi:
10.1016/s0006-8993(03)02682-9
. [PMID: 12834881] - Xiaojun Mu, Robert D Azbill, Joe E Springer. NBQX treatment improves mitochondrial function and reduces oxidative events after spinal cord injury.
Journal of neurotrauma.
2002 Aug; 19(8):917-27. doi:
10.1089/089771502320317078
. [PMID: 12225652] - Makoto Ohgoh, Takahisa Hanada, Terence Smith, Toshihide Hashimoto, Masataka Ueno, Yoshiharu Yamanishi, Masahiko Watanabe, Yukio Nishizawa. Altered expression of glutamate transporters in experimental autoimmune encephalomyelitis.
Journal of neuroimmunology.
2002 Apr; 125(1-2):170-8. doi:
10.1016/s0165-5728(02)00029-2
. [PMID: 11960654] - E Engidawork, F Loidl, Y Chen, C Kohlhauser, S Stoeckler, E Dell'Anna, B Lubec, G Lubec, M Goiny, J Gross, K Andersson, M Herrera-Marschitz. Comparison between hypothermia and glutamate antagonism treatments on the immediate outcome of perinatal asphyxia.
Experimental brain research.
2001 Jun; 138(3):375-83. doi:
10.1007/s002210100710
. [PMID: 11460776] - S Eliasof, H B McIlvain, R E Petroski, A C Foster, J Dunlop. Pharmacological characterization of threo-3-methylglutamic acid with excitatory amino acid transporters in native and recombinant systems.
Journal of neurochemistry.
2001 Apr; 77(2):550-7. doi:
10.1046/j.1471-4159.2001.00253.x
. [PMID: 11299317] - R F Regan, Y Guo. Magnesium deprivation decreases cellular reduced glutathione and causes oxidative neuronal death in murine cortical cultures.
Brain research.
2001 Jan; 890(1):177-83. doi:
10.1016/s0006-8993(00)03156-5
. [PMID: 11164781]